PubRank

Herman Waldmann

Author PubWeight™ 140.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 2005 10.16
2 Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity 2012 4.98
3 Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A 2009 4.25
4 Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation. Lancet 2005 4.09
5 Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J Immunol 2004 3.62
6 Identification of regulatory T cells in tolerated allografts. J Exp Med 2002 3.60
7 High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution. Blood 2002 2.96
8 Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005 2.74
9 Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen. Blood 2002 2.56
10 The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol 2005 2.44
11 Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proc Natl Acad Sci U S A 2009 2.22
12 The plasticity and stability of regulatory T cells. Nat Rev Immunol 2013 2.15
13 Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc Natl Acad Sci U S A 2003 2.14
14 Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase. Int Immunol 2004 2.13
15 Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. Diabetes 2005 2.10
16 Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood 2002 1.85
17 Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol 2002 1.85
18 Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. J Clin Invest 2010 1.83
19 Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression. Transplantation 2005 1.66
20 Dominant transplantation tolerance impairs CD8+ T cell function but not expansion. Nat Immunol 2002 1.55
21 Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it. J Immunol 2006 1.51
22 Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance. J Exp Med 2011 1.43
23 Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration. Blood 2004 1.40
24 Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients. Blood 2009 1.37
25 Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance. Proc Natl Acad Sci U S A 2007 1.34
26 Immune privilege induced by regulatory T cells in transplantation tolerance. Immunol Rev 2006 1.27
27 A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts. J Immunol 2007 1.27
28 Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms. Immunol Rev 2003 1.26
29 Regulatory T cells overexpress a subset of Th2 gene transcripts. J Immunol 2002 1.25
30 The role of Sp1 and NF-kappa B in regulating CD40 gene expression. J Biol Chem 2001 1.23
31 Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years. Am J Transplant 2005 1.22
32 mTOR signalling and metabolic regulation of T cell differentiation. Curr Opin Immunol 2010 1.20
33 IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J Immunol 2004 1.18
34 Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link. Immunol Rev 2010 1.17
35 Generation of anti-inflammatory adenosine by leukocytes is regulated by TGF-β. Eur J Immunol 2011 1.16
36 The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nat Commun 2011 1.15
37 Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation. J Immunol 2007 1.12
38 Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells. Proc Natl Acad Sci U S A 2004 1.11
39 A novel strategy to reduce the immunogenicity of biological therapies. J Immunol 2010 1.10
40 The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model. J Gen Virol 2002 1.10
41 Enhanced production of IL-10 by dendritic cells deficient in CIITA. J Immunol 2005 1.09
42 Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells. Trends Immunol 2005 1.07
43 Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen. J Immunol 2004 1.06
44 In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology. J Virol 2005 1.06
45 CD8+ lymphocytes do not mediate protection against acute superinfection 20 days after vaccination with a live attenuated simian immunodeficiency virus. J Virol 2005 1.05
46 Tmem176B and Tmem176A are associated with the immature state of dendritic cells. J Leukoc Biol 2010 1.05
47 Embryonic stem cells: overcoming the immunological barriers to cell replacement therapy. Curr Stem Cell Res Ther 2009 1.04
48 TGF-β-mediated Foxp3 gene expression is cooperatively regulated by Stat5, Creb, and AP-1 through CNS2. J Immunol 2013 1.02
49 Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: twelve-year outcomes. Arthritis Rheum 2008 1.01
50 Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. J Leukoc Biol 2007 0.97
51 Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes. J Clin Pharmacol 2010 0.96
52 Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance. Sci Transl Med 2011 0.96
53 Harnessing FOXP3+ regulatory T cells for transplantation tolerance. J Clin Invest 2014 0.95
54 Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis. Arch Ophthalmol 2004 0.95
55 Biomarkers of transplantation tolerance: more hopeful than helpful? Front Immunol 2011 0.94
56 Reconstitution of the Epstein-Barr virus-specific cytotoxic T-lymphocyte response following T-cell-depleted myeloablative and nonmyeloablative allogeneic stem cell transplantation. Blood 2003 0.94
57 TGF-β in transplantation tolerance. Curr Opin Immunol 2011 0.93
58 Embryonic stem cells and the challenge of transplantation tolerance. Trends Immunol 2004 0.93
59 Anti-CD45 monoclonal antibody YAML568: A promising radioimmunoconjugate for targeted therapy of acute leukemia. J Nucl Med 2006 0.92
60 Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity. PLoS Pathog 2013 0.92
61 Induction of immunological tolerance/hyporesponsiveness in baboons with a nondepleting CD4 antibody. J Immunol 2004 0.92
62 Structural basis for ligand-mediated mouse GITR activation. Proc Natl Acad Sci U S A 2008 0.92
63 Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells. Regen Med 2009 0.91
64 Exacerbation of delayed-type hypersensitivity responses in EBV-induced gene-3 (EBI-3)-deficient mice. Immunol Lett 2010 0.91
65 T- and B-cell immune reconstitution and clinical outcome in patients with multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell transplantation with an alemtuzumab-containing conditioning regimen followed by escalated donor lymphocyte infusions. Br J Haematol 2003 0.90
66 Infectious tolerance: therapeutic potential. Curr Opin Immunol 2010 0.90
67 Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target. PLoS One 2009 0.90
68 Dominant transplantation tolerance. Opinion. Curr Opin Immunol 2003 0.90
69 Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockade. Hum Gene Ther 2015 0.90
70 Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby. J Clin Invest 2004 0.89
71 Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice. Immunology 2010 0.89
72 Immune reconstitution at 6 months following T-cell depleted hematopoietic stem cell transplantation is predictive for treatment outcome. Transplantation 2002 0.89
73 MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation. J Immunol 2009 0.89
74 Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning. BMC Immunol 2006 0.88
75 A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across an major histocompatibility complex barrier. Stem Cells 2010 0.87
76 Resistance of regulatory T cells to glucocorticoid-induced [corrected] TNFR family-related protein (GITR) during Plasmodium yoelii infection. Eur J Immunol 2005 0.87
77 Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge. Eur J Immunol 2014 0.87
78 Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance. Transpl Int 2003 0.86
79 Reduced-intensity transplantation with in vivo T-cell depletion and adjuvant dose-escalating donor lymphocyte infusions for chemotherapy-sensitive myeloma: limited efficacy of graft-versus-tumor activity. Biol Blood Marrow Transplant 2003 0.86
80 T-cell depletion with Campath-1H "in the bag" for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival. Br J Haematol 2003 0.86
81 Regulatory cells and transplantation tolerance. Cold Spring Harb Perspect Med 2013 0.86
82 Embryonic stem cells: protecting pluripotency from alloreactivity. Curr Opin Immunol 2007 0.86
83 Alemtuzumab (CAMPATH-1H) for the treatment of acute rejection in kidney transplant recipients: long-term follow-up. Transplantation 2009 0.85
84 Induction of Immunological Tolerance as a Therapeutic Procedure. Microbiol Spectr 2016 0.83
85 Antibody-induced transplantation tolerance: the role of dominant regulation. Immunol Res 2003 0.82
86 Immunology: protection and privilege. Nature 2006 0.82
87 Enhancement of humoral and cellular immunity with an anti-glucocorticoid-induced tumour necrosis factor receptor monoclonal antibody. Immunology 2010 0.82
88 Tolerogenicity is not an absolute property of a dendritic cell. Eur J Immunol 2010 0.82
89 Foxp3 expression is required for the induction of therapeutic tissue tolerance. J Immunol 2012 0.81
90 CD3 monoclonal antibodies: a first step towards operational immune tolerance in the clinic. Rev Diabet Stud 2012 0.80
91 Embryonic stem cells: a novel source of dendritic cells for clinical applications. Int Immunopharmacol 2005 0.80
92 Ectopic transplantation of tissues under the kidney capsule. Methods Mol Biol 2007 0.80
93 Enhanced murine contact hypersensitivity by depletion of endogenous regulatory T cells in the sensitization phase. J Dermatol Sci 2010 0.79
94 Secreted and transmembrane 1A is a novel co-stimulatory ligand. PLoS One 2013 0.79
95 Serial analysis of gene expression provides new insights into regulatory T cells. Semin Immunol 2003 0.78
96 Probing dendritic cell function by guiding the differentiation of embryonic stem cells. Methods Enzymol 2003 0.78
97 Regulatory T cells and transplantation tolerance. Immunotherapy 2013 0.78
98 Cell replacement therapy and the evasion of destructive immunity. Stem Cell Rev 2005 0.78
99 Gene expression in the Gitr locus is regulated by NF-κB and Foxp3 through an enhancer. J Immunol 2014 0.78
100 Reprogramming the immune system using antibodies. Methods Mol Biol 2006 0.77
101 The new immunosuppression: just kill the T cell. Nat Med 2003 0.76
102 A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development. Int J Dev Biol 2010 0.76
103 Pediatric immunohematopoietic stem cell transplantation at a tertiary care center in Cape Town. Hematol Oncol Stem Cell Ther 2010 0.76
104 Genetic modification of dendritic cells through the directed differentiation of embryonic stem cells. Methods Mol Biol 2007 0.76
105 Preservation of recall immunity in anti-CD3-treated recent onset type 1 diabetes patients. Diabetes Metab Res Rev 2011 0.75
106 Transplantation--caught in the crossfire! Nat Immunol 2002 0.75
107 Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naïve T cells in dendritic cell clustering. Eur J Immunol 2012 0.75
108 SAGE analysis of cell types involved in tolerance induction. Methods Mol Biol 2007 0.75
109 Regulation of the immune response. Curr Opin Immunol 2010 0.75
110 Stable lines of genetically modified dendritic cells from mouse embryonic stem cells. Transplantation 2003 0.75
111 Immunological tolerance. Front Immunol 2010 0.75