Published in Eur J Immunol on February 13, 2014
Adaptive immune responses to Candida albicans infection. Virulence (2015) 0.92
Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis. PLoS One (2015) 0.92
Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells. Cytokine (2015) 0.85
Brothers in arms: Th17 and Treg responses in Candida albicans immunity. PLoS Pathog (2014) 0.83
C/EBPβ Promotes Immunity to Oral Candidiasis through Regulation of β-Defensins. PLoS One (2015) 0.79
Remission of systemic lupus erythematosus disease activity with regulatory cytokine interleukin (IL)-35 in Murphy Roths Large (MRL)/lpr mice. Clin Exp Immunol (2015) 0.78
TLR-2 Signaling Promotes IL-17A Production in CD4+CD25+Foxp3+ Regulatory Cells during Oropharyngeal Candidiasis. Pathogens (2015) 0.77
Experimental autoimmune encephalomyelitis development is aggravated by Candida albicans infection. J Immunol Res (2015) 0.77
Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU). PLoS One (2016) 0.75
Regulatory CD4+CD25+ T Cells Dampen Inflammatory Disease in Murine Mycoplasma Pneumonia and Promote IL-17 and IFN-γ Responses. PLoS One (2016) 0.75
Immunoregulation in Fungal Diseases. Microorganisms (2016) 0.75
A Candida albicans Strain Expressing Mammalian Interleukin-17A Results in Early Control of Fungal Growth during Disseminated Infection. Infect Immun (2015) 0.75
Control of regulatory T cell development by the transcription factor Foxp3. Science (2003) 40.32
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med (2003) 26.05
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature (2008) 14.26
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol (1998) 11.26
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol (2010) 9.72
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol (2002) 9.18
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis (2004) 6.54
Peripheral education of the immune system by colonic commensal microbiota. Nature (2011) 5.80
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A (2006) 5.50
Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity (2012) 4.98
Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity (2011) 4.86
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur J Immunol (2007) 4.54
Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature (2012) 4.33
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc Natl Acad Sci U S A (2009) 4.10
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo. J Exp Med (2012) 3.40
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol (2004) 3.13
IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood (2009) 3.04
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. J Exp Med (2012) 2.97
Expression of Helios in peripherally induced Foxp3+ regulatory T cells. J Immunol (2011) 2.80
Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathog (2008) 2.80
Mice with disseminated candidiasis die of progressive sepsis. J Infect Dis (2005) 2.42
Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis. J Exp Med (1992) 2.37
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells. Blood (2012) 2.00
CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model. Immunity (2011) 2.00
Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology. J Immunol (2003) 1.96
IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo. J Immunol (2011) 1.89
One year prospective survey of Candida bloodstream infections in Scotland. J Med Microbiol (2007) 1.87
Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2. Immunity (2011) 1.87
Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun (2003) 1.78
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans. J Leukoc Biol (2011) 1.76
Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc. J Immunol (2007) 1.66
The changing epidemiology of healthcare-associated candidemia over three decades. Diagn Microbiol Infect Dis (2012) 1.56
Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance. J Exp Med (2011) 1.43
A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J Immunol (2007) 1.41
Early-expressed chemokines predict kidney immunopathology in experimental disseminated Candida albicans infections. PLoS One (2009) 1.31
Peripherally induced tregs - role in immune homeostasis and autoimmunity. Front Immunol (2013) 1.24
Developmental plasticity of Foxp3+ regulatory T cells. Curr Opin Immunol (2010) 1.15
Cutting edge: in the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection. J Immunol (2012) 0.96
CD4(+) T-cell responses to Epstein-Barr virus (EBV) latent membrane protein 1 in infectious mononucleosis and EBV-associated non-Hodgkin lymphoma: Th1 in active disease but Tr1 in remission. Br J Haematol (2007) 0.88
Hospital-acquired infection surveillance in a neurosurgical intensive care unit. J Hosp Infect (2006) 0.87
Mouse intravenous challenge models and applications. Methods Mol Biol (2012) 0.78
Induction of colonic regulatory T cells by indigenous Clostridium species. Science (2010) 16.71
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol (2007) 10.71
Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev (2006) 10.24
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med (2005) 7.87
Hidden killers: human fungal infections. Sci Transl Med (2012) 7.10
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med (2009) 5.55
An integrated model of the recognition of Candida albicans by the innate immune system. Nat Rev Microbiol (2008) 5.13
Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity (2012) 4.98
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches. Science (2009) 4.80
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol (2004) 4.59
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest (2006) 4.45
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A (2009) 4.25
Clinical evidence of a graft-versus-Hodgkin's-lymphoma effect after reduced-intensity allogeneic transplantation. Lancet (2005) 4.09
Candida orthopsilosis and Candida metapsilosis spp. nov. to replace Candida parapsilosis groups II and III. J Clin Microbiol (2005) 3.93
Antifungal agents: mechanisms of action. Trends Microbiol (2003) 3.74
Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J Immunol (2004) 3.62
Identification of regulatory T cells in tolerated allografts. J Exp Med (2002) 3.60
Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology (2010) 3.51
Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members. J Biol Chem (2003) 3.41
Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity (2009) 3.33
Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat. J Biol Chem (2008) 2.97
High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution. Blood (2002) 2.96
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol (2005) 2.74
Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha-induced genes in bone cells. J Leukoc Biol (2004) 2.73
Identification of common transcriptional regulatory elements in interleukin-17 target genes. J Biol Chem (2006) 2.65
Ectopic expression of URA3 can influence the virulence phenotypes and proteome of Candida albicans but can be overcome by targeted reintegration of URA3 at the RPS10 locus. Eukaryot Cell (2004) 2.63
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol (2008) 2.62
EST mining and functional expression assays identify extracellular effector proteins from the plant pathogen Phytophthora. Genome Res (2003) 2.57
Limiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen. Blood (2002) 2.56
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma. Blood (2003) 2.47
The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol (2005) 2.44
Molecular phylogenetics of Candida albicans. Eukaryot Cell (2007) 2.41
Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans. Genome Res (2009) 2.24
Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proc Natl Acad Sci U S A (2009) 2.22
Stimulation of chitin synthesis rescues Candida albicans from echinocandins. PLoS Pathog (2008) 2.19
Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy. Cytokine (2008) 2.19
Optimization and validation of multilocus sequence typing for Candida albicans. J Clin Microbiol (2003) 2.18
Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice. J Immunol (2009) 2.17
The plasticity and stability of regulatory T cells. Nat Rev Immunol (2013) 2.15
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc Natl Acad Sci U S A (2003) 2.14
Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13
Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase. Int Immunol (2004) 2.13
Niche-specific regulation of central metabolic pathways in a fungal pathogen. Cell Microbiol (2006) 2.12
Identification, immunomodulatory activity, and immunogenicity of the major helper T-cell epitope on the K blood group antigen. Blood (2012) 2.10
Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. Diabetes (2005) 2.10
Population structure and properties of Candida albicans, as determined by multilocus sequence typing. J Clin Microbiol (2005) 2.04
Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment. J Leukoc Biol (2004) 2.03
The PKC, HOG and Ca2+ signalling pathways co-ordinately regulate chitin synthesis in Candida albicans. Mol Microbiol (2007) 2.00
CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model. Immunity (2011) 2.00
Th17 cells in immunity to Candida albicans. Cell Host Microbe (2012) 1.97
CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1. Mol Cell Biol (2004) 1.96
Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans. J Biol Chem (2005) 1.95
Pattern recognition: recent insights from Dectin-1. Curr Opin Immunol (2009) 1.93
One year prospective survey of Candida bloodstream infections in Scotland. J Med Microbiol (2007) 1.87
Regulatory T cells, derived from naïve CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance. Transplantation (2005) 1.86
Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression. Proc Natl Acad Sci U S A (2007) 1.85
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol (2002) 1.85
Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. J Clin Invest (2010) 1.83
Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function. J Leukoc Biol (2011) 1.82
Fungal echinocandin resistance. Fungal Genet Biol (2009) 1.78
Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17. J Biol Chem (2004) 1.77
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans. J Leukoc Biol (2011) 1.76
IL-17 and the Th17 lineage in systemic lupus erythematosus. Curr Opin Rheumatol (2008) 1.73
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics (2007) 1.73
The fine specificity and cytokine profile of T-helper cells responsive to the alpha3 chain of type IV collagen in Goodpasture's disease. J Am Soc Nephrol (2003) 1.70
Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence. J Biol Chem (2005) 1.70
IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. J Immunol (2010) 1.69
NADPH oxidase limits innate immune responses in the lungs in mice. PLoS One (2010) 1.69
Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity. Fungal Genet Biol (2008) 1.67
1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A. Mol Cell Biol (2011) 1.67
Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression. Transplantation (2005) 1.66
Comparative genomics of MAP kinase and calcium-calcineurin signalling components in plant and human pathogenic fungi. Fungal Genet Biol (2009) 1.66
Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence. J Biol Chem (2004) 1.66
Multilocus sequence typing for differentiation of strains of Candida tropicalis. J Clin Microbiol (2005) 1.66
Interleukin-17: a novel inflammatory cytokine that bridges innate and adaptive immunity. Front Biosci (2008) 1.60
IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain. Sci Signal (2009) 1.57
Dominant transplantation tolerance impairs CD8+ T cell function but not expansion. Nat Immunol (2002) 1.55
Recognition and blocking of innate immunity cells by Candida albicans chitin. Infect Immun (2011) 1.54
Stage specific assessment of Candida albicans phagocytosis by macrophages identifies cell wall composition and morphogenesis as key determinants. PLoS Pathog (2012) 1.54
Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome. N Engl J Med (2014) 1.53
Glucose promotes stress resistance in the fungal pathogen Candida albicans. Mol Biol Cell (2009) 1.52
Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it. J Immunol (2006) 1.51
Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition. J Biol Chem (2004) 1.51
Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem (2008) 1.50
Infection-related gene expression in Candida albicans. Curr Opin Microbiol (2007) 1.50
Proteomic and phenotypic profiling of the amphibian pathogen Batrachochytrium dendrobatidis shows that genotype is linked to virulence. Mol Ecol (2009) 1.49
GFP as a quantitative reporter of gene regulation in Candida albicans. Yeast (2004) 1.47
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J Immunol (2013) 1.45