Published in Mol Cell Biol on January 11, 2010
PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome. Mol Cell (2013) 1.15
The cell cycle regulated transcriptome of Trypanosoma brucei. PLoS One (2011) 1.09
Proteomic analysis reveals diverse classes of arginine methylproteins in mitochondria of trypanosomes. Mol Cell Proteomics (2012) 0.98
A second mitochondrial DNA primase is essential for cell growth and kinetoplast minicircle DNA replication in Trypanosoma brucei. Eukaryot Cell (2011) 0.87
Three mitochondrial DNA polymerases are essential for kinetoplast DNA replication and survival of bloodstream form Trypanosoma brucei. Eukaryot Cell (2011) 0.86
Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes. Nucleic Acids Res (2015) 0.85
The Arabidopsis At1g30680 gene encodes a homologue to the phage T7 gp4 protein that has both DNA primase and DNA helicase activities. BMC Plant Biol (2013) 0.84
Mitochondrial heat shock protein machinery hsp70/hsp40 is indispensable for proper mitochondrial DNA maintenance and replication. MBio (2015) 0.84
Dynamic localization of Trypanosoma brucei mitochondrial DNA polymerase ID. Eukaryot Cell (2012) 0.78
Interactions of a replication initiator with histone H1-like proteins remodel the condensed mitochondrial genome. J Biol Chem (2011) 0.78
U-insertion/deletion RNA editing multiprotein complexes and mitochondrial ribosomes in Leishmania tarentolae are located in antipodal nodes adjacent to the kinetoplast DNA. Mitochondrion (2015) 0.77
PrimPol-A new polymerase on the block. Mol Cell Oncol (2014) 0.76
A passion for parasites. J Biol Chem (2014) 0.76
PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast. J Biol Chem (2016) 0.76
Mitochondrial DNA replication: a PrimPol perspective. Biochem Soc Trans (2017) 0.75
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol (1999) 11.77
Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur J Biochem (1996) 10.23
Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters. J Biol Chem (2000) 4.96
Complex management: RNA editing in trypanosomes. Trends Biochem Sci (2005) 3.69
New culture medium for maintenance of tsetse tissues and growth of trypanosomatids. J Protozool (1977) 2.91
A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos. Proc Natl Acad Sci U S A (1982) 2.53
Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members. Nucleic Acids Res (2005) 2.49
Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination. Eukaryot Cell (2005) 2.39
Fellowship of the rings: the replication of kinetoplast DNA. Trends Parasitol (2005) 2.21
Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates. Curr Genet (2005) 2.01
Localization of a type II DNA topoisomerase to two sites at the periphery of the kinetoplast DNA of Crithidia fasciculata. Cell (1988) 1.98
Ribonucleotides associated with a gap in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum. J Biol Chem (1986) 1.97
DNA replication. J Biol Chem (1988) 1.85
Multiple mitochondrial DNA polymerases in Trypanosoma brucei. Mol Cell (2002) 1.64
Trypanosomes have six mitochondrial DNA helicases with one controlling kinetoplast maxicircle replication. Mol Cell (2009) 1.64
Kinetoplast DNA network: evolution of an improbable structure. Eukaryot Cell (2002) 1.62
RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA. EMBO J (2001) 1.62
Evolution of the protists and protistan parasites from the perspective of molecular systematics. Int J Parasitol (1998) 1.60
The structure and replication of kinetoplast DNA. Curr Mol Med (2004) 1.59
Free minicircles of kinetoplast DNA in Crithidia fasciculata. J Biol Chem (1979) 1.59
Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro. Proc Natl Acad Sci U S A (2008) 1.52
A gap at a unique location in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum. J Biol Chem (1985) 1.37
Intramitochondrial location and dynamics of Crithidia fasciculata kinetoplast minicircle replication intermediates. J Cell Biol (2001) 1.35
Structural characterization of site-specific discontinuities associated with replication origins of minicircle DNA from Crithidia fasciculata. J Biol Chem (1987) 1.33
Intramitochondrial localization of universal minicircle sequence-binding protein, a trypanosomatid protein that binds kinetoplast minicircle replication origins. J Cell Biol (2001) 1.31
Conserved sequence blocks in kinetoplast minicircles from diverse species of trypanosomes. Mol Cell Biol (1989) 1.30
Mitochondrial DNA ligases of Trypanosoma brucei. Eukaryot Cell (2005) 1.28
The kinetoplast structure-specific endonuclease I is related to the 5' exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase beta during replication. Proc Natl Acad Sci U S A (1999) 1.27
Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes. J Biol Chem (2003) 1.24
The topology of the kinetoplast DNA network. Cell (1995) 1.23
p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation. EMBO J (2007) 1.23
Nucleus-encoded histone H1-like proteins are associated with kinetoplast DNA in the trypanosomatid Crithidia fasciculata. Mol Cell Biol (1996) 1.20
Sequences within the 5' untranslated region regulate the levels of a kinetoplast DNA topoisomerase mRNA during the cell cycle. Mol Cell Biol (1996) 1.19
Role of p38 in replication of Trypanosoma brucei kinetoplast DNA. Mol Cell Biol (2006) 1.15
A mitochondrial DNA primase from the trypanosomatid Crithidia fasciculata. J Biol Chem (1997) 1.14
Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis. Annu Rev Pharmacol Toxicol (1995) 1.13
Identification of cis and trans elements involved in the cell cycle regulation of multiple genes in Crithidia fasciculata. Mol Cell Biol (1999) 1.13
Kinetoplast maxicircle DNA replication in Crithidia fasciculata and Trypanosoma brucei. Mol Cell Biol (1995) 1.10
Characterization of the Crithidia fasciculata mRNA cycling sequence binding proteins. Mol Cell Biol (2001) 1.09
A trypanosome mitochondrial RNA polymerase is required for transcription and replication. J Biol Chem (2002) 1.08
A mitochondrial topoisomerase IA essential for late theta structure resolution in African trypanosomes. Mol Microbiol (2007) 1.03
Effect of hydroxyurea on procyclic Trypanosoma brucei: an unconventional mechanism for achieving synchronous growth. Eukaryot Cell (2007) 1.02
Mitochondrial DNA ligase in Crithidia fasciculata. Proc Natl Acad Sci U S A (2004) 1.02
Synthesis and processing of kinetoplast DNA minicircles in Trypanosoma equiperdum. Mol Cell Biol (1989) 1.01
Assigning functions to genes: identification of S-phase expressed genes in Leishmania major based on post-transcriptional control elements. Nucleic Acids Res (2005) 0.98
Release of RNA polymerase from vero cell mitochondria after herpes simplex virus type 1 infection. J Virol (1990) 0.97
Disruption of the Crithidia fasciculata KAP1 gene results in structural rearrangement of the kinetoplast disc. Mol Biochem Parasitol (2001) 0.97
The Crithidia fasciculata KAP1 gene encodes a highly basic protein associated with kinetoplast DNA. Mol Biochem Parasitol (1998) 0.97
Replication of kinetoplast DNA in Trypanosoma equiperdum. Minicircle H strand fragments which map at specific locations. J Biol Chem (1989) 0.96
Redox potential regulates binding of universal minicircle sequence binding protein at the kinetoplast DNA replication origin. Eukaryot Cell (2004) 0.95
A structure-specific DNA endonuclease is enriched in kinetoplasts purified from Crithidia fasciculata. Nucleic Acids Res (1998) 0.93
Binding of the universal minicircle sequence binding protein at the kinetoplast DNA replication origin. J Biol Chem (2006) 0.93
Cell cycle-dependent localization and properties of a second mitochondrial DNA ligase in Crithidia fasciculata. Eukaryot Cell (2006) 0.90
RNA interference of Trypanosoma brucei topoisomerase IB: both subunits are essential. Mol Biochem Parasitol (2004) 0.90
Presence of multiple mRNA cycling sequence element-binding proteins in Crithidia fasciculata. J Biol Chem (2003) 0.90
Specific discontinuities in Leishmania tarentolae minicircles map within universally conserved sequence blocks. Mol Biochem Parasitol (1989) 0.89
Tandem arrangement of two genes encoding kinetoplast-associated H1 histone-like proteins. Mol Biochem Parasitol (1997) 0.86
A single-stranded DNA binding protein binds the origin of replication of the duplex kinetoplast DNA. Proc Natl Acad Sci U S A (1995) 0.86
RNA primer removal and gap filling on a model minicircle replication intermediate. Mol Biochem Parasitol (2001) 0.84
Presence of a poly(A) binding protein and two proteins with cell cycle-dependent phosphorylation in Crithidia fasciculata mRNA cycling sequence binding protein II. Eukaryot Cell (2004) 0.83
Stem-loop silencing reveals that a third mitochondrial DNA polymerase, POLID, is required for kinetoplast DNA replication in trypanosomes. Eukaryot Cell (2008) 0.83
Identification of new kinetoplast DNA replication proteins in trypanosomatids based on predicted S-phase expression and mitochondrial targeting. Eukaryot Cell (2007) 0.81
The Crithidia fasciculata RNH1 gene encodes both nuclear and mitochondrial isoforms of RNase H. Nucleic Acids Res (2001) 0.80
Specific recognition of the replication origins of the kinetoplast DNA. Acta Microbiol Immunol Hung (2002) 0.76
Mitochondrial DNA ligases of Trypanosoma brucei. Eukaryot Cell (2005) 1.28
Mitochondrial DNA ligase in Crithidia fasciculata. Proc Natl Acad Sci U S A (2004) 1.02
Sequence elements in both the intergenic space and the 3' untranslated region of the Crithidia fasciculata KAP3 gene are required for cell cycle regulation of KAP3 mRNA. Eukaryot Cell (2003) 0.96
Cell cycle-dependent localization and properties of a second mitochondrial DNA ligase in Crithidia fasciculata. Eukaryot Cell (2006) 0.90
Presence of multiple mRNA cycling sequence element-binding proteins in Crithidia fasciculata. J Biol Chem (2003) 0.90
A second mitochondrial DNA primase is essential for cell growth and kinetoplast minicircle DNA replication in Trypanosoma brucei. Eukaryot Cell (2011) 0.87
Mitochondrial histone-like DNA-binding proteins are essential for normal cell growth and mitochondrial function in Crithidia fasciculata. Eukaryot Cell (2004) 0.86
Presence of a poly(A) binding protein and two proteins with cell cycle-dependent phosphorylation in Crithidia fasciculata mRNA cycling sequence binding protein II. Eukaryot Cell (2004) 0.83
Identification of new kinetoplast DNA replication proteins in trypanosomatids based on predicted S-phase expression and mitochondrial targeting. Eukaryot Cell (2007) 0.81
Structure of discontinuities in kinetoplast DNA-associated minicircles during S phase in Crithidia fasciculata. Nucleic Acids Res (2007) 0.79