|
1
|
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate.
|
Cell
|
2010
|
2.91
|
|
2
|
GLI transcription factors: mediators of oncogenic Hedgehog signalling.
|
Eur J Cancer
|
2006
|
2.63
|
|
3
|
Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma.
|
Oncogene
|
2002
|
1.99
|
|
4
|
Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2.
|
Cancer Res
|
2004
|
1.98
|
|
5
|
Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway.
|
Cancer Res
|
2009
|
1.78
|
|
6
|
GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter.
|
J Invest Dermatol
|
2004
|
1.76
|
|
7
|
Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.
|
Mol Cell Biol
|
2006
|
1.72
|
|
8
|
Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.
|
Cell
|
2012
|
1.65
|
|
9
|
FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma.
|
J Invest Dermatol
|
2004
|
1.34
|
|
10
|
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells.
|
EMBO Mol Med
|
2012
|
1.27
|
|
11
|
Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes.
|
Genomics
|
2006
|
1.21
|
|
12
|
Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays.
|
J Biol Chem
|
2002
|
1.20
|
|
13
|
RNA expression profiling at the single molecule level.
|
Genome Res
|
2006
|
1.08
|
|
14
|
Non-consensus GLI binding sites in Hedgehog target gene regulation.
|
BMC Mol Biol
|
2010
|
1.07
|
|
15
|
Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
|
PLoS One
|
2013
|
1.04
|
|
16
|
The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells.
|
Oncogene
|
2004
|
1.04
|
|
17
|
Cyclopamine treatment of full-blown Hh/Ptch-associated RMS partially inhibits Hh/Ptch signaling, but not tumor growth.
|
Mol Carcinog
|
2008
|
1.04
|
|
18
|
Expression profiling of aging in the human skin.
|
Exp Gerontol
|
2006
|
0.98
|
|
19
|
GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells.
|
J Biol Chem
|
2008
|
0.97
|
|
20
|
Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation.
|
Virchows Arch
|
2009
|
0.97
|
|
21
|
Cooperative Hedgehog-EGFR signaling.
|
Front Biosci (Landmark Ed)
|
2012
|
0.95
|
|
22
|
GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes.
|
Carcinogenesis
|
2008
|
0.92
|
|
23
|
Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII.
|
Cancer Res
|
2010
|
0.91
|
|
24
|
IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site.
|
J Immunol
|
2003
|
0.91
|
|
25
|
Efficient manipulation of Hedgehog/GLI signaling using retroviral expression systems.
|
Methods Mol Biol
|
2007
|
0.91
|
|
26
|
Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.
|
Gastroenterology
|
2012
|
0.89
|
|
27
|
Gene expression pattern following photodynamic treatment of the carcinoma cell line A-431 analysed by cDNA arrays.
|
Int J Oncol
|
2002
|
0.81
|
|
28
|
Neuronal differentiation in basal cell carcinoma: possible relationship to Hedgehog pathway activation?
|
J Pathol
|
2009
|
0.80
|
|
29
|
Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis.
|
Nat Commun
|
2015
|
0.78
|
|
30
|
Expression analysis of multiple myeloma CD138 negative progenitor cells using single molecule microarray readout.
|
J Biotechnol
|
2013
|
0.78
|