Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells.

PubWeight™: 1.67‹?› | Rank: Top 3%

🔗 View Article (PMID 20074550)

Published in Biochem Biophys Res Commun on January 13, 2010

Authors

Ying Teng1, Xiuwen Wang, Yawei Wang, Daoxin Ma

Author Affiliations

1: Department of Chemotherapy, Cancer Center, Shandong University, Jinan 250012, China.

Articles citing this

Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes. Pharmacol Rev (2012) 2.31

The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell. PLoS One (2013) 1.65

Cancer stem cells and drug resistance: the potential of nanomedicine. Nanomedicine (Lond) (2012) 1.54

Salinomycin as a drug for targeting human cancer stem cells. J Biomed Biotechnol (2012) 1.50

Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes. Mol Cancer (2013) 1.41

Aldehyde dehydrogenase 1, a potential marker for cancer stem cells in human sarcoma. PLoS One (2012) 1.19

Clinicopathological significance of non-small cell lung cancer with high prevalence of Oct-4 tumor cells. J Exp Clin Cancer Res (2012) 1.17

Epigenetic regulation of cancer stem cells in liver cancer: current concepts and clinical implications. J Hepatol (2010) 1.16

The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells. PLoS One (2012) 1.16

Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment. PLoS One (2011) 1.14

Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review. World J Exp Med (2015) 1.10

Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. J Nutr Biochem (2011) 1.10

Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells. Neuro Oncol (2012) 1.09

Wnt/β-catenin pathway as a potential prognostic and predictive marker in patients with advanced ovarian cancer. J Ovarian Res (2014) 0.98

ABC transporters in CSCs membranes as a novel target for treating tumor relapse. Front Pharmacol (2014) 0.98

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy. Oncotarget (2015) 0.97

Skeletal metastasis: treatments, mouse models, and the Wnt signaling. Chin J Cancer (2013) 0.95

Low molecular weight heparin ablates lung cancer cisplatin-resistance by inducing proteasome-mediated ABCG2 protein degradation. PLoS One (2012) 0.93

Biological rationale for the design of polymeric anti-cancer nanomedicines. J Drug Target (2012) 0.93

n-Butyl benzyl phthalate promotes breast cancer progression by inducing expression of lymphoid enhancer factor 1. PLoS One (2012) 0.91

Insulin and the lung: connecting asthma and metabolic syndrome. J Allergy (Cairo) (2013) 0.89

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine. Mol Cancer (2015) 0.89

The function of SARI in modulating epithelial-mesenchymal transition and lung adenocarcinoma metastasis. PLoS One (2012) 0.88

Evidence of the cross talk between Wnt and Notch signaling pathways in non-small-cell lung cancer (NSCLC): Notch3-siRNA weakens the effect of LiCl on the cell cycle of NSCLC cell lines. J Cancer Res Clin Oncol (2010) 0.87

Liver cancer stem cells. Int J Hepatol (2011) 0.86

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells. BMC Cancer (2015) 0.86

Long non-coding RNAs in non-small cell lung cancer as biomarkers and therapeutic targets. J Cell Mol Med (2014) 0.85

Curcumin: updated molecular mechanisms and intervention targets in human lung cancer. Int J Mol Sci (2012) 0.85

Wnt blockers inhibit the proliferation of lung cancer stem cells. Drug Des Devel Ther (2015) 0.85

Cancer stem cell theory: therapeutic implications for nanomedicine. Int J Nanomedicine (2013) 0.84

A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells. Oncotarget (2016) 0.83

Aberrant microRNAs expression in CD133⁺/CD326⁺ human lung adenocarcinoma initiating cells from A549. Mol Cells (2012) 0.83

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells. Free Radic Biol Med (2012) 0.83

Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells. Nucleus (2013) 0.83

Cancer stem cells: progress and challenges in lung cancer. Stem Cell Investig (2014) 0.83

Wnt signaling pathway pharmacogenetics in non-small cell lung cancer. Pharmacogenomics J (2014) 0.82

Stem cells in gastrointestinal cancers: The road less travelled. World J Stem Cells (2014) 0.81

HPMA copolymer-based combination therapy toxic to both prostate cancer stem/progenitor cells and differentiated cells induces durable anti-tumor effects. J Control Release (2013) 0.81

Gastric tumor-initiating CD44(+) cells and epithelial-mesenchymal transition are inhibited by γ-secretase inhibitor DAPT. Oncol Lett (2015) 0.80

Stemness and plasticity of lung cancer cells: paving the road for better therapy. Onco Targets Ther (2014) 0.80

Cancer stem cells: a metastasizing menace! Cancer Med (2016) 0.79

Targeting cancer stem cells by using the nanoparticles. Int J Nanomedicine (2015) 0.79

The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells. Cancers (Basel) (2015) 0.79

Curcumin Inhibits Gastric Carcinoma Cell Growth and Induces Apoptosis by Suppressing the Wnt/β-Catenin Signaling Pathway. Med Sci Monit (2017) 0.79

Aberrant Wnt/β-catenin signaling and elevated expression of stem cell proteins are associated with osteosarcoma side population cells of high tumorigenicity. Mol Med Rep (2015) 0.78

β-Catenin is important for cancer stem cell generation and tumorigenic activity in nasopharyngeal carcinoma. Acta Biochim Biophys Sin (Shanghai) (2016) 0.78

Prognostic value of wingless-type proteins in non-small cell lung cancer patients: a meta-analysis. Transl Lung Cancer Res (2016) 0.77

A regulatory loop containing miR-26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells. Sci Rep (2015) 0.77

Intracellular signals of lung cancer cells as possible therapeutic targets. Cancer Sci (2015) 0.77

TRAF4 enhances oral squamous cell carcinoma cell growth, invasion and migration by Wnt-β-catenin signaling pathway. Int J Clin Exp Pathol (2015) 0.77

The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt. PLoS One (2015) 0.77

β‑catenin signaling pathway regulates cisplatin resistance in lung adenocarcinoma cells by upregulating Bcl‑xl. Mol Med Rep (2016) 0.77

Lithium chloride has a biphasic effect on prostate cancer stem cells and a proportional effect on midkine levels. Oncol Lett (2016) 0.76

Reprogramming mediated radio-resistance of 3D-grown cancer cells. J Radiat Res (2015) 0.76

Feedback Activation of Basic Fibroblast Growth Factor Signaling via the Wnt/β-Catenin Pathway in Skin Fibroblasts. Front Pharmacol (2017) 0.75

Role of Wnt signaling on proliferation of menstrual blood derived stem cells. J Stem Cells Regen Med (2013) 0.75

MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer. Oncotarget (2017) 0.75

Stem/progenitor cells in endogenous repairing responses: new toolbox for the treatment of acute lung injury. J Transl Med (2016) 0.75

Combination therapy targeting both cancer stem-like cells and bulk tumor cells for improved efficacy of breast cancer treatment. Cancer Biol Ther (2016) 0.75

Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway. Oncotarget (2016) 0.75

Constitutive expression of Wnt/β‑catenin target genes promotes proliferation and invasion of liver cancer stem cells. Mol Med Rep (2016) 0.75

Genes potentially associated with cisplatin resistance of lung cancer cells. Dokl Biochem Biophys (2011) 0.75

The roles of ARHGAP10 in the proliferation, migration and invasion of lung cancer cells. Oncol Lett (2017) 0.75

Suppression of a cancer stem-like phenotype mediated by alpha-lipoic acid in human lung cancer cells through down-regulation of β-catenin and Oct-4. Cell Oncol (Dordr) (2017) 0.75

Bladder cancer stem cells: clonal origin and therapeutic perspectives. Oncotarget (2017) 0.75

Articles by these authors

Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood (2007) 2.32

Th22 and related cytokines in inflammatory and autoimmune diseases. Expert Opin Ther Targets (2012) 2.14

Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transition. Mol Biosyst (2012) 2.00

Non-sterilized fermentative production of polymer-grade L-lactic acid by a newly isolated thermophilic strain Bacillus sp. 2-6. PLoS One (2009) 1.46

Down-regulation of Notch-1 increases co-cultured Jurkat cell sensitivity to chemotherapy. Leuk Lymphoma (2009) 1.42

[Results of randomized, multicenter, double-blind phase III trial of rh-endostatin (YH-16) in treatment of advanced non-small cell lung cancer patients]. Zhongguo Fei Ai Za Zhi (2005) 1.38

Downregulated MEG3 activates autophagy and increases cell proliferation in bladder cancer. Mol Biosyst (2013) 1.37

Both CD133+ and CD133- subpopulations of A549 and H446 cells contain cancer-initiating cells. Cancer Sci (2009) 1.34

Elevated interleukin-21 correlated to Th17 and Th1 cells in patients with immune thrombocytopenia. J Clin Immunol (2009) 1.18

Elevated profile of Th17, Th1 and Tc1 cells in patients with immune thrombocytopenic purpura. Haematologica (2009) 1.11

Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines. Leuk Res (2008) 1.06

Curcumin inhibits proliferation and invasion of osteosarcoma cells through inactivation of Notch-1 signaling. FEBS J (2012) 1.05

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells. J Hematol Oncol (2013) 1.05

The imbalance of Th17/Treg in patients with uterine cervical cancer. Clin Chim Acta (2011) 1.02

Elevated profiles of Th22 cells and correlations with Th17 cells in patients with immune thrombocytopenia. Hum Immunol (2012) 1.01

RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer. Oncol Rep (2010) 1.01

Cell-mediated lysis of autologous platelets in chronic idiopathic thrombocytopenic purpura. Eur J Haematol (2006) 1.01

Use of scalp hair as indicator of human exposure to heavy metals in an electronic waste recycling area. Environ Pollut (2009) 0.99

Debromination of decabrominated diphenyl ether by resin-bound iron nanoparticles. Environ Sci Technol (2007) 0.96

Production of L-lactic acid by a thermophilic Bacillus mutant using sodium hydroxide as neutralizing agent. Bioresour Technol (2010) 0.96

Astaxanthin ameliorates lung fibrosis in vivo and in vitro by preventing transdifferentiation, inhibiting proliferation, and promoting apoptosis of activated cells. Food Chem Toxicol (2013) 0.95

Increased Th22 cells as well as Th17 cells in patients with adult T-cell acute lymphoblastic leukemia. Clin Chim Acta (2013) 0.94

miR-372 down-regulates the oncogene ATAD2 to influence hepatocellular carcinoma proliferation and metastasis. BMC Cancer (2014) 0.94

Cross-talk between Notch and EGFR signaling in human breast cancer cells. Cancer Invest (2009) 0.92

Perchlorate in sewage sludge, rice, bottled water and milk collected from different areas in China. Environ Int (2007) 0.92

Concurrent chemoradiotherapy with or without adjuvant chemotherapy in intermediate and locoregionally advanced nasopharyngeal carcinoma. Tumour Biol (2013) 0.90

Evaluation of Soxhlet extraction, accelerated solvent extraction and microwave-assisted extraction for the determination of polychlorinated biphenyls and polybrominated diphenyl ethers in soil and fish samples. Anal Chim Acta (2010) 0.90

Occurrence of perfluorinated compounds in fish from Qinghai-Tibetan Plateau. Environ Int (2009) 0.90

Seroprevalence and risk factors of human cytomegalovirus infection in the eastern Chinese population. Arch Virol (2009) 0.89

Aberrant expression of Treg-associated cytokine IL-35 along with IL-10 and TGF-β in acute myeloid leukemia. Oncol Lett (2012) 0.89

Syntaxin-11 is expressed in primary human monocytes/macrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG-opsonized target cells. Br J Haematol (2008) 0.88

Bufalin exerts antitumor effects by inducing cell cycle arrest and triggering apoptosis in pancreatic cancer cells. Tumour Biol (2013) 0.88

Spatial distribution of polychlorinated biphenyls (PCBs) and polybrominated biphenyl ethers (PBDEs) in an e-waste dismantling region in Southeast China: Use of apple snail (Ampullariidae) as a bioindicator. Chemosphere (2010) 0.88

Aberrant T helper 17 cells and related cytokines in bone marrow microenvironment of patients with acute myeloid leukemia. Clin Dev Immunol (2013) 0.87

Th17 cells in autoimmune diseases. Front Med (2015) 0.87

Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway. Carcinogenesis (2012) 0.85

Polysaccharide from Ganoderma atrum evokes antitumor activity via Toll-like receptor 4-mediated NF-κB and mitogen-activated protein kinase signaling pathways. J Agric Food Chem (2013) 0.85

Prognostic impact of δ-like ligand 4 and Notch1 in acute myeloid leukemia. Oncol Rep (2012) 0.84

Levels and distributions of hexachlorobutadiene and three chlorobenzenes in biosolids from wastewater treatment plants and in soils within and surrounding a chemical plant in China. Environ Sci Technol (2014) 0.84

Distribution of Th17 cells and Foxp3-expressing T cells in tumor-infiltrating lymphocytes in patients with uterine cervical cancer. Clin Chim Acta (2012) 0.84

Simultaneous targeting of MCL1 and ABCB1 as a novel strategy to overcome drug resistance in human leukaemia. Br J Haematol (2009) 0.84

The role of IL-21 in hematological malignancies. Cytokine (2011) 0.84

MDM2 309 polymorphism is associated with missed abortion. Hum Reprod (2009) 0.84

The p53-HDM2 gene-gene polymorphism interaction is associated with the development of missed abortion. Hum Reprod (2011) 0.84

Polybrominated diphenyl ethers (PBDEs) and mercury in fish from lakes of the Tibetan Plateau. Chemosphere (2011) 0.84

Treg cells in different forms of uterine cancer. Clin Chim Acta (2012) 0.83

Presence and partitioning behavior of polyfluorinated iodine alkanes in environmental matrices around a fluorochemical manufacturing plant: another possible source for perfluorinated carboxylic acids? Environ Sci Technol (2010) 0.83

Perspectives on the inclusion of perfluorooctane sulfonate into the Stockholm Convention on Persistent Organic Pollutants. Environ Sci Technol (2009) 0.83

Organochlorine pesticides and PCBs in fish from lakes of the Tibetan Plateau and the implications. Environ Pollut (2010) 0.83

Occurrence of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls pollution in sediments from the Haihe River and Dagu Drainage River in Tianjin City, China. Chemosphere (2007) 0.82

The impact of CDA A79C gene polymorphisms on the response and hematologic toxicity in gemcitabine-treated patients: a meta-analysis. Int J Biol Markers (2014) 0.81

Phosphoinositide-3-kinase inhibition enhances radiosensitization of cervical cancer in vivo. Int J Gynecol Cancer (2011) 0.81

More than 45% of A549 and H446 cells are cancer initiating cells: evidence from cloning and tumorigenic analyses. Oncol Rep (2009) 0.81

Optimization of H2O2 dosage in microwave-H2O2 process for sludge pretreatment with uniform design method. J Environ Sci (China) (2012) 0.80

Association of Dll4/notch and HIF-1a -VEGF signaling in the angiogenesis of missed abortion. PLoS One (2013) 0.80

IL-21 and IL-12 inhibit differentiation of Treg and TH17 cells and enhance cytotoxicity of peripheral blood mononuclear cells in patients with cervical cancer. Int J Gynecol Cancer (2011) 0.80

Paclitaxel-octreotide conjugates in tumor growth inhibition of A549 human non-small cell lung cancer xenografted into nude mice. Eur J Pharmacol (2008) 0.80

Influence of e-waste dismantling and its regulations: temporal trend, spatial distribution of heavy metals in rice grains, and its potential health risk. Environ Sci Technol (2013) 0.80

Levels and vertical distributions of PCBs, PBDEs, and OCPs in the atmospheric boundary layer: observation from the Beijing 325-m meteorological tower. Environ Sci Technol (2009) 0.79

Production of uridine 5'-monophosphate by Corynebacterium ammoniagenes ATCC 6872 using a statistically improved biocatalytic process. Appl Microbiol Biotechnol (2007) 0.79

Sludge reduction potential of the activated sludge process by integrating an oligochaete reactor. J Hazard Mater (2008) 0.79

Levels and distribution patterns of short chain chlorinated paraffins in sewage sludge of wastewater treatment plants in China. Environ Pollut (2011) 0.79

Concentrations and composition profiles of benzotriazole UV stabilizers in municipal sewage sludge in China. Environ Sci Technol (2012) 0.79

Imatinib achieved complete cytogenetic response in a CML patient received 32-year indirubin and its derivative treatment. Leuk Res (2009) 0.79

Identification and evaluation of a novel heterocyclic brominated flame retardant tris(2,3-dibromopropyl) isocyanurate in environmental matrices near a manufacturing plant in southern China. Environ Sci Technol (2009) 0.79

[Cadaver renal transplantation and multivariate analysis for graft survival: a clinical review of 2 016 cases]. Zhonghua Wai Ke Za Zhi (2002) 0.79

Tris(2,3-dibromopropyl) isocyanurate, hexabromocyclododecanes, and polybrominated diphenyl ethers in mollusks from Chinese Bohai Sea. Environ Sci Technol (2012) 0.79

Th17 and Treg cells in bone related diseases. Clin Dev Immunol (2013) 0.79

Changes in cell ultrastructure and inhibition of JAK1/STAT3 signaling pathway in CBRH-7919 cells with astaxanthin. Toxicol Mech Methods (2012) 0.79

Genistein exhibits anti-cancer effects via down-regulating FoxM1 in H446 small-cell lung cancer cells. Tumour Biol (2013) 0.79

Temporal trends of PCBs, PCDD/Fs and PBDEs in soils from an E-waste dismantling area in East China. Environ Sci Process Impacts (2013) 0.79

Notch1 signaling is irresponsible to the anti-leukemic effect of HDACis in B-ALL Nalm-6 cells. Ann Hematol (2012) 0.79

Distribution of PCBs and PBDEs in soils along the altitudinal gradients of Balang Mountain, the east edge of the Tibetan Plateau. Environ Pollut (2011) 0.78

Pathway of Toll-like receptor 7/B cell activating factor/B cell activating factor receptor plays a role in immune thrombocytopenia in vivo. PLoS One (2011) 0.78

Trace determination of airborne polyfluorinated iodine alkanes using multisorbent thermal desorption/gas chromatography/high resolution mass spectrometry. J Chromatogr A (2010) 0.78

Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) in biosolids from municipal wastewater treatment plants in China. Chemosphere (2012) 0.78

Distribution and trophic transfer of short-chain chlorinated paraffins in an aquatic ecosystem receiving effluents from a sewage treatment plant. Environ Sci Technol (2011) 0.78

Antitumor effects of cytosine deaminase and thymidine kinase fusion suicide gene under the control of mdr1 promoter in mdr1 positive leukemia cells. Leuk Lymphoma (2007) 0.78

Identification of spatial genetic boundaries using a multifractal model in human population genetics. Hum Biol (2005) 0.78

Current levels and composition profiles of emerging halogenated flame retardants and dehalogenated products in sewage sludge from municipal wastewater treatment plants in China. Environ Sci Technol (2014) 0.78

Bismuth and chromium co-doped strontium titanates and their photocatalytic properties under visible light irradiation. Phys Chem Chem Phys (2015) 0.78

Bioaccumulation of PCDD/Fs, PCBs and PBDEs by earthworms in field soils of an E-waste dismantling area in China. Environ Int (2013) 0.78

Aberrant expression and association of VEGF and Dll4/Notch pathway molecules under hypoxia in patients with lung cancer. Histol Histopathol (2013) 0.77

Behavior, fate, and mass loading of short chain chlorinated paraffins in an advanced municipal sewage treatment plant. Environ Sci Technol (2013) 0.77

Temporal trends (2005-2009) of PCDD/Fs, PCBs, PBDEs in rice hulls from an e-waste dismantling area after stricter environmental regulations. Chemosphere (2012) 0.77

Spatial distribution and inter-year variation of hexabromocyclododecane (HBCD) and tris-(2,3-dibromopropyl) isocyanurate (TBC) in farm soils at a peri-urban region. Chemosphere (2012) 0.77

Trophic transfer of mercury and methylmercury in an aquatic ecosystem impacted by municipal sewage effluents in Beijing, China. J Environ Sci (China) (2010) 0.77

Bortezomib and IL-12 produce synergetic anti-multiple myeloma effects with reduced toxicity to natural killer cells. Anticancer Drugs (2014) 0.77

Optical digital coherent detection technology enabled flexible and ultra-fast quantitative phase imaging. Opt Express (2016) 0.77

Simultaneous determination of hexabromocyclododecanes and tris (2,3-dibromopropyl) isocyanurate using LC-APCI-MS/MS. Talanta (2010) 0.77

Altitude dependence of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in surface soil from Tibetan Plateau, China. Chemosphere (2009) 0.76

Investigation of perfluorinated compounds (PFCs) in mollusks from coastal waters in the Bohai Sea of China. J Environ Monit (2009) 0.76

Distribution and temporal trends of butyltins monitored by molluscs along the Chinese Bohai coast from 2002 to 2005. Environ Int (2008) 0.76