Published in Chem Biol Interact on January 13, 2010
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Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet (2005) 14.39
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell (2010) 14.18
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Inferring genetic networks and identifying compound mode of action via expression profiling. Science (2003) 9.10
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Wisdom of crowds for robust gene network inference. Nat Methods (2012) 6.91
Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Mol Cell (2010) 5.33
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Programmable cells: interfacing natural and engineered gene networks. Proc Natl Acad Sci U S A (2004) 4.72
How antibiotics kill bacteria: from targets to networks. Nat Rev Microbiol (2010) 4.65
Synthetic gene networks that count. Science (2009) 4.54
Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell (2008) 4.47
Cellular decision making and biological noise: from microbes to mammals. Cell (2011) 4.44
Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature (2011) 4.06
Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Mol Syst Biol (2007) 3.98
Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nat Biotechnol (2005) 3.89
Diversity-based, model-guided construction of synthetic gene networks with predicted functions. Nat Biotechnol (2009) 3.86
Bacterial charity work leads to population-wide resistance. Nature (2010) 3.50
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Vibrating insoles and balance control in elderly people. Lancet (2003) 3.48
RNA synthetic biology. Nat Biotechnol (2006) 3.37
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Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. Nature (2013) 3.02
Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A (2009) 3.01
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A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell (2007) 2.83
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell (2009) 2.74
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science (2012) 2.72
Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. Mol Cell (2012) 2.56
Combinatorial promoter design for engineering noisy gene expression. Proc Natl Acad Sci U S A (2007) 2.40
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A (2009) 2.37
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A synthetic biology framework for programming eukaryotic transcription functions. Cell (2012) 2.32
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med (2012) 2.26
Synthetic gene network for entraining and amplifying cellular oscillations. Phys Rev Lett (2002) 2.24
A network biology approach to prostate cancer. Mol Syst Biol (2007) 2.07
Noise-enhanced balance control in patients with diabetes and patients with stroke. Ann Neurol (2006) 2.06
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell (2012) 1.96
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A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol (2012) 1.93
Role of reactive oxygen species in antibiotic action and resistance. Curr Opin Microbiol (2009) 1.92
Aging, muscle activity, and balance control: physiologic changes associated with balance impairment. Gait Posture (2003) 1.84
Exposure misclassification in studies of agricultural pesticides: insights from biomonitoring. Epidemiology (2006) 1.77
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell (2013) 1.68
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc Natl Acad Sci U S A (2010) 1.66
Genetic switchboard for synthetic biology applications. Proc Natl Acad Sci U S A (2012) 1.60
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nat Biotechnol (2013) 1.59
Trends in covalency for d- and f-element metallocene dichlorides identified using chlorine K-edge X-ray absorption spectroscopy and time-dependent density functional theory. J Am Chem Soc (2009) 1.55
Tuning and controlling gene expression noise in synthetic gene networks. Nucleic Acids Res (2010) 1.52
Heterogeneous bacterial persisters and engineering approaches to eliminate them. Curr Opin Microbiol (2011) 1.47
Tunable signal processing in synthetic MAP kinase cascades. Cell (2011) 1.45
Antibiotics and the gut microbiota. J Clin Invest (2014) 1.39
Microbial persistence and the road to drug resistance. Cell Host Microbe (2013) 1.37
Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance. Proc Natl Acad Sci U S A (2013) 1.29
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Fungicidal drugs induce a common oxidative-damage cellular death pathway. Cell Rep (2013) 1.19
Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proc Natl Acad Sci U S A (2010) 1.18
Iterative plug-and-play methodology for constructing and modifying synthetic gene networks. Nat Methods (2012) 1.17
Unraveling the physiological complexities of antibiotic lethality. Annu Rev Pharmacol Toxicol (2014) 1.16
Noise-enhanced balance control in older adults. Neuroreport (2002) 1.16
Need for recovery from work: evaluating short-term effects of working hours, patterns and schedules. Ergonomics (2003) 1.16
Functional characterization of bacterial sRNAs using a network biology approach. Proc Natl Acad Sci U S A (2011) 1.14
A network biology approach to aging in yeast. Proc Natl Acad Sci U S A (2009) 1.11
Valproic acid extends Caenorhabditis elegans lifespan. Aging Cell (2008) 1.10
Regulation of physiologic actions of LRRK2: focus on autophagy. Neurodegener Dis (2011) 1.07
Chlorpyrifos exposure in farm families: results from the farm family exposure study. J Expo Sci Environ Epidemiol (2006) 1.07
Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni. Elife (2013) 1.07
Genomic approaches to deconstruct pluripotency. Annu Rev Genomics Hum Genet (2011) 1.06
Noise-enhanced vibrotactile sensitivity in older adults, patients with stroke, and patients with diabetic neuropathy. Arch Phys Med Rehabil (2002) 1.06
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Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Sci Transl Med (2014) 1.03
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Microbial environments confound antibiotic efficacy. Nat Chem Biol (2011) 0.99
Cholinesterase inhibition in chlorpyrifos workers: Characterization of biomarkers of exposure and response in relation to urinary TCPy. J Expo Sci Environ Epidemiol (2008) 0.99
Biomonitoring of 2,4-dichlorophenoxyacetic acid exposure and dose in farm families. Environ Health Perspect (2006) 0.97
Generation of spirotricyclic site-differentiated cyclotriphosphazenes: a solvent-free approach to multidentate N/O donor ligand systems. Inorg Chem (2004) 0.97
Microbiology. Antioxidant strategies to tolerate antibiotics. Science (2011) 0.95
Whole mount in situ hybridization methodology for Schistosoma mansoni. Mol Biochem Parasitol (2011) 0.95
Systems biology strikes gold. Cell (2009) 0.94
Mortality update of workers exposed to acrylonitrile in The Netherlands. J Occup Environ Med (2004) 0.92
Predicting the dynamic postural control response from quiet-stance behavior in elderly adults. J Biomech (2003) 0.92
Molecular biology. Signal processing in single cells. Science (2005) 0.91
Enhancing tactile sensation in older adults with electrical noise stimulation. Neuroreport (2002) 0.91
Incomplete follow-up in the National Cancer Institute's formaldehyde worker study and the impact on subsequent reanalyses and causal evaluations. Regul Toxicol Pharmacol (2010) 0.90
Introduction to focus issue: quantitative approaches to genetic networks. Chaos (2013) 0.89
Networking opportunities for bacteria. Cell (2008) 0.88
A weight of evidence approach to causal inference. J Clin Epidemiol (2008) 0.88
Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria. BMC Genomics (2014) 0.87
Plug-and-play with RNA. Nat Biotechnol (2005) 0.87
Increased cancer burden among pesticide applicators and others due to pesticide exposure. CA Cancer J Clin (2013) 0.87
Mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin at a trichlorophenol plant in New Zealand. J Occup Environ Med (2009) 0.86
A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite. Nat Commun (2013) 0.86