Published in Proc Natl Acad Sci U S A on January 13, 2010
Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue. Proc Natl Acad Sci U S A (2011) 2.15
Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides. Proc Natl Acad Sci U S A (2011) 1.65
Germline stem cells. Cold Spring Harb Perspect Biol (2011) 1.53
GLD-4-mediated translational activation regulates the size of the proliferative germ cell pool in the adult C. elegans germ line. PLoS Genet (2014) 1.44
Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline. Dev Cell (2015) 1.41
What does the concept of the stem cell niche really mean today? BMC Biol (2012) 1.32
Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the C. elegans germline. Development (2011) 1.31
The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells. Development (2010) 1.09
Stem cell proliferation versus meiotic fate decision in Caenorhabditis elegans. Adv Exp Med Biol (2013) 1.07
The C. elegans adult male germline: stem cells and sexual dimorphism. Dev Biol (2010) 1.04
Germline stem cells: origin and destiny. Cell Stem Cell (2012) 1.04
Molecular regulation of the mitosis/meiosis decision in multicellular organisms. Cold Spring Harb Perspect Biol (2011) 1.04
Cyclin E and Cdk2 control GLD-1, the mitosis/meiosis decision, and germline stem cells in Caenorhabditis elegans. PLoS Genet (2011) 1.02
The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells. Development (2012) 0.93
A DTC niche plexus surrounds the germline stem cell pool in Caenorhabditis elegans. PLoS One (2014) 0.92
The microRNA pathway controls germ cell proliferation and differentiation in C. elegans. Cell Res (2012) 0.91
Macro-level modeling of the response of C. elegans reproduction to chronic heat stress. PLoS Comput Biol (2012) 0.88
Chemokine and Fgf signalling act as opposing guidance cues in formation of the lateral line primordium. Development (2012) 0.87
Analysis of Germline Stem Cell Differentiation Following Loss of GLP-1 Notch Activity in Caenorhabditis elegans. Genetics (2015) 0.87
Mitosis-meiosis and sperm-oocyte fate decisions are separable regulatory events. Proc Natl Acad Sci U S A (2013) 0.86
A model of stem cell population dynamics: in silico analysis and in vivo validation. Development (2012) 0.86
Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets requirements of design to minimize mutation accumulation. BMC Biol (2015) 0.86
Germline stem cells: stems of the next generation. Curr Opin Cell Biol (2010) 0.84
C. elegans FOG-3/Tob can either promote or inhibit germline proliferation, depending on gene dosage and genetic context. Oncogene (2012) 0.83
GPI-anchor synthesis is indispensable for the germline development of the nematode Caenorhabditis elegans. Mol Biol Cell (2012) 0.82
C. elegans GLP-1/Notch activates transcription in a probability gradient across the germline stem cell pool. Elife (2016) 0.81
PUF-8 negatively regulates RAS/MAPK signalling to promote differentiation of C. elegans germ cells. Development (2013) 0.81
Live imaging reveals active infiltration of mitotic zone by its stem cell niche. Integr Biol (Camb) (2013) 0.80
Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways. G3 (Bethesda) (2013) 0.80
Ovarian germline stem cells: an unlimited source of oocytes? Fertil Steril (2014) 0.80
Translational activation maintains germline tissue homeostasis during adulthood. Worm (2015) 0.79
Cell-cycle quiescence maintains Caenorhabditis elegans germline stem cells independent of GLP-1/Notch. Elife (2015) 0.79
Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images. BMC Bioinformatics (2015) 0.78
Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line. PLoS Genet (2016) 0.76
Cell cycle features of C. elegans germline stem/progenitor cells vary temporally and spatially. Dev Biol (2015) 0.76
Multicolor two-photon imaging of endogenous fluorophores in living tissues by wavelength mixing. Sci Rep (2017) 0.75
Live-imaging analysis of germ cell proliferation in the C. elegans adult supports a stochastic model for stem cell proliferation. Dev Biol (2017) 0.75
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Hematopoiesis: an evolving paradigm for stem cell biology. Cell (2008) 11.95
A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A (2008) 10.09
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell (2008) 9.92
Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development (1990) 8.37
Out of Eden: stem cells and their niches. Science (2000) 8.31
Asymmetric and symmetric stem-cell divisions in development and cancer. Nature (2006) 7.32
A PUF family portrait: 3'UTR regulation as a way of life. Trends Genet (2002) 5.71
Mechanisms of asymmetric stem cell division. Cell (2008) 5.59
Stem cell niche: structure and function. Annu Rev Cell Dev Biol (2005) 5.33
glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell (1987) 5.07
EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron (2002) 5.06
The tortoise and the hair: slow-cycling cells in the stem cell race. Cell (2009) 3.90
A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans. Nature (2002) 3.90
A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans. Nature (2002) 3.54
Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans. Annu Rev Cell Dev Biol (2007) 3.26
Regeneration of male germline stem cells by spermatogonial dedifferentiation in vivo. Science (2004) 3.20
Differentiating germ cells can revert into functional stem cells in Drosophila melanogaster ovaries. Nature (2004) 3.06
gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics (1995) 2.94
Synapsis and chiasma formation in Caenorhabditis elegans require HIM-3, a meiotic chromosome core component that functions in chromosome segregation. Genes Dev (1999) 2.86
Notch signaling in stem cell systems. Stem Cells (2006) 2.82
Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science (2009) 2.73
GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Dev Biol (1996) 2.55
The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans. EMBO J (1999) 2.54
Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes Dev (1995) 2.41
Genetic regulation of entry into meiosis in Caenorhabditis elegans. Development (1998) 2.28
Cellular analyses of the mitotic region in the Caenorhabditis elegans adult germ line. Mol Biol Cell (2006) 2.23
Mouse differentiating spermatogonia can generate germinal stem cells in vivo. Nat Cell Biol (2008) 2.05
FBF-1 and FBF-2 regulate the size of the mitotic region in the C. elegans germline. Dev Cell (2004) 2.03
Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors. Development (1997) 1.94
GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans. Genetics (2004) 1.92
GLD-3, a bicaudal-C homolog that inhibits FBF to control germline sex determination in C. elegans. Dev Cell (2002) 1.78
Control of the proliferation versus meiotic development decision in the C. elegans germline through regulation of GLD-1 protein accumulation. Development (2003) 1.78
Differential timing of S phases, X chromosome replication, and meiotic prophase in the C. elegans germ line. Dev Biol (2007) 1.73
Multi-pathway control of the proliferation versus meiotic development decision in the Caenorhabditis elegans germline. Dev Biol (2004) 1.72
The gon-1 gene is required for gonadal morphogenesis in Caenorhabditis elegans. Dev Biol (1999) 1.70
The GLD-2 poly(A) polymerase activates gld-1 mRNA in the Caenorhabditis elegans germ line. Proc Natl Acad Sci U S A (2006) 1.59
EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans. Mol Biol Cell (2000) 1.52
DjPum, a homologue of Drosophila Pumilio, is essential to planarian stem cell maintenance. Development (2005) 1.46
The regulatory network controlling the proliferation-meiotic entry decision in the Caenorhabditis elegans germ line. Curr Top Dev Biol (2006) 1.39
Caenorhabditis elegans germ line: a model for stem cell biology. Dev Dyn (2007) 1.21
Quantitative analysis of germline mitosis in adult C. elegans. Dev Biol (2006) 1.20
Purpose and regulation of stem cells: a systems-biology view from the Caenorhabditis elegans germ line. J Pathol (2009) 0.92
Analysis of the C. elegans germline stem cell region. Methods Mol Biol (2008) 0.85
Casting back to stem cells. Nat Cell Biol (2009) 0.80
Asymmetric and symmetric stem-cell divisions in development and cancer. Nature (2006) 7.32
A PUF family portrait: 3'UTR regulation as a way of life. Trends Genet (2002) 5.71
A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans. Nature (2002) 3.90
A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans. Nature (2002) 3.54
Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans. Annu Rev Cell Dev Biol (2007) 3.26
A beta-catenin identified by functional rather than sequence criteria and its role in Wnt/MAPK signaling. Cell (2005) 2.26
Cellular analyses of the mitotic region in the Caenorhabditis elegans adult germ line. Mol Biol Cell (2006) 2.23
A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality. Nature (2012) 2.04
FBF-1 and FBF-2 regulate the size of the mitotic region in the C. elegans germline. Dev Cell (2004) 2.03
GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans. Genetics (2004) 1.92
Mammalian GLD-2 homologs are poly(A) polymerases. Proc Natl Acad Sci U S A (2004) 1.88
Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C. elegans. Curr Biol (2006) 1.87
GLD-3, a bicaudal-C homolog that inhibits FBF to control germline sex determination in C. elegans. Dev Cell (2002) 1.78
Germline proliferation and its control. WormBook (2005) 1.73
Genome-wide analysis of mRNA targets for Caenorhabditis elegans FBF, a conserved stem cell regulator. Proc Natl Acad Sci U S A (2010) 1.66
Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2. Curr Biol (2002) 1.63
The GLD-2 poly(A) polymerase activates gld-1 mRNA in the Caenorhabditis elegans germ line. Proc Natl Acad Sci U S A (2006) 1.59
POP-1 controls axis formation during early gonadogenesis in C. elegans. Development (2002) 1.58
FBF and its dual control of gld-1 expression in the Caenorhabditis elegans germline. Genetics (2009) 1.52
Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. PLoS Genet (2007) 1.51
Regulation of the mitosis/meiosis decision in the Caenorhabditis elegans germline. Philos Trans R Soc Lond B Biol Sci (2003) 1.48
A conserved PUF-Ago-eEF1A complex attenuates translation elongation. Nat Struct Mol Biol (2012) 1.47
GON-1 and fibulin have antagonistic roles in control of organ shape. Curr Biol (2004) 1.45
LIP-1 phosphatase controls the extent of germline proliferation in Caenorhabditis elegans. EMBO J (2005) 1.40
Dose-dependent control of proliferation and sperm specification by FOG-1/CPEB. Development (2005) 1.38
The sys-1 and sys-3 genes cooperate with Wnt signaling to establish the proximal-distal axis of the Caenorhabditis elegans gonad. Genetics (2004) 1.37
Reciprocal asymmetry of SYS-1/beta-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2007) 1.36
What does the concept of the stem cell niche really mean today? BMC Biol (2012) 1.32
C. elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis. RNA (2008) 1.32
A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity. RNA (2008) 1.25
Scratching the niche that controls Caenorhabditis elegans germline stem cells. Semin Cell Dev Biol (2009) 1.22
Redundant control of the Caenorhabditis elegans sperm/oocyte switch by PUF-8 and FBF-1, two distinct PUF RNA-binding proteins. Proc Natl Acad Sci U S A (2005) 1.22
A new look at TCF and beta-catenin through the lens of a divergent C. elegans Wnt pathway. Dev Cell (2009) 1.17
The C. elegans Hand gene controls embryogenesis and early gonadogenesis. Development (2003) 1.15
The oogenic germline starvation response in C. elegans. PLoS One (2011) 1.14
Chemical reprogramming of Caenorhabditis elegans germ cell fate. Nat Chem Biol (2009) 1.11
GLD-2/RNP-8 cytoplasmic poly(A) polymerase is a broad-spectrum regulator of the oogenesis program. Proc Natl Acad Sci U S A (2010) 1.10
Antagonism between GLD-2 binding partners controls gamete sex. Dev Cell (2009) 1.10
The C. elegans adult male germline: stem cells and sexual dimorphism. Dev Biol (2010) 1.04
Divergence of Pumilio/fem-3 mRNA binding factor (PUF) protein specificity through variations in an RNA-binding pocket. J Biol Chem (2011) 1.04
Cyclin E and Cdk2 control GLD-1, the mitosis/meiosis decision, and germline stem cells in Caenorhabditis elegans. PLoS Genet (2011) 1.02
Discovery of two GLP-1/Notch target genes that account for the role of GLP-1/Notch signaling in stem cell maintenance. Proc Natl Acad Sci U S A (2014) 0.98
RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. J Biol Chem (2012) 0.98
The C. elegans SYS-1 protein is a bona fide beta-catenin. Dev Cell (2008) 0.97
The impact of mitotic versus interphase chromatin architecture on the molecular flow of EGFP by pair correlation analysis. Biophys J (2011) 0.97
Evolution of discrete Notch-like receptors from a distant gene duplication in Caenorhabditis. Evol Dev (2002) 0.97
TRA-1/GLI controls development of somatic gonadal precursors in C. elegans. Development (2004) 0.97
Developmental expression of FOG-1/CPEB protein and its control in the Caenorhabditis elegans hermaphrodite germ line. Dev Dyn (2007) 0.97
Phosphorylation state of a Tob/BTG protein, FOG-3, regulates initiation and maintenance of the Caenorhabditis elegans sperm fate program. Proc Natl Acad Sci U S A (2011) 0.94
Cyclin D regulation of a sexually dimorphic asymmetric cell division. Dev Cell (2005) 0.93
gon-14 functions with class B and class C synthetic multivulva genes to control larval growth in Caenorhabditis elegans. Genetics (2005) 0.92
Germline stem cells and their regulation in the nematode Caenorhabditis elegans. Adv Exp Med Biol (2013) 0.91
Identification of a conserved interface between PUF and CPEB proteins. J Biol Chem (2012) 0.90
A forkhead protein controls sexual identity of the C. elegans male somatic gonad. Development (2004) 0.89
The N- or C-terminal domains of DSH-2 can activate the C. elegans Wnt/beta-catenin asymmetry pathway. Dev Biol (2009) 0.87
C. elegans HLH-2/E/Daughterless controls key regulatory cells during gonadogenesis. Dev Biol (2009) 0.86
Mitosis-meiosis and sperm-oocyte fate decisions are separable regulatory events. Proc Natl Acad Sci U S A (2013) 0.86
Germ-line induction of the Caenorhabditis elegans vulva. Proc Natl Acad Sci U S A (2006) 0.85
Analysis of the C. elegans germline stem cell region. Methods Mol Biol (2008) 0.85
The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline. Biochim Biophys Acta (2012) 0.82
Growth control by EGF repeats of the C. elegans Fibulin-1C isoform. J Cell Biol (2006) 0.81
mig-38, a novel gene that regulates distal tip cell turning during gonadogenesis in C. elegans hermaphrodites. Dev Biol (2012) 0.79
Preparation and immunolabeling of Caenorhabditis elegans. Cold Spring Harb Protoc (2009) 0.78
Tissue-specific modification of gld-2 mRNA in C. elegans: likely C-to-U editing. RNA (2004) 0.78