AMPA receptors and synaptic plasticity: a chemist's perspective.

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The cell biology of synaptic plasticity. Science (2011) 1.37

AMPA receptors as a molecular target in epilepsy therapy. Acta Neurol Scand Suppl (2013) 1.13

Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn. Eur J Neurosci (2010) 0.87

AMPA receptor mediated behavioral plasticity in the isolated rat spinal cord. Behav Brain Res (2012) 0.77

Chemical labelling for visualizing native AMPA receptors in live neurons. Nat Commun (2017) 0.75

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Structural basis of long-term potentiation in single dendritic spines. Nature (2004) 11.50

Specific covalent labeling of recombinant protein molecules inside live cells. Science (1998) 9.32

Learning induces long-term potentiation in the hippocampus. Science (2006) 7.46

Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking. Science (2003) 7.33

The cell biology of synaptic plasticity: AMPA receptor trafficking. Annu Rev Cell Dev Biol (2007) 6.91

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature (2009) 6.81

Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science (1999) 6.77

Storage of spatial information by the maintenance mechanism of LTP. Science (2006) 6.71

Synaptic plasticity and addiction. Nat Rev Neurosci (2007) 6.08

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving. Nature (2008) 6.01

Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell (2001) 6.00

Synaptic AMPA receptor plasticity and behavior. Neuron (2009) 5.58

Dendritic protein synthesis, synaptic plasticity, and memory. Cell (2006) 5.18

Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science (1999) 4.56

Regulatory mechanisms of AMPA receptors in synaptic plasticity. Nat Rev Neurosci (2007) 4.24

Quantum dots as cellular probes. Annu Rev Biomed Eng (2005) 4.19

The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity. Neuron (2007) 4.19

Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach. Neuron (2009) 4.18

Targeting quantum dots to surface proteins in living cells with biotin ligase. Proc Natl Acad Sci U S A (2005) 4.15

Long-lasting potentiation of synaptic transmission in the dentate area of the unanaestetized rabbit following stimulation of the perforant path. J Physiol (1973) 4.12

Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons. J Neurosci (1996) 3.97

Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature (2005) 3.88

Bright ideas for chemical biology. ACS Chem Biol (2008) 3.84

Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors. Nat Neurosci (2004) 3.64

Regulation of AMPA receptor lateral movements. Nature (2002) 3.56

Silent synapses and the emergence of a postsynaptic mechanism for LTP. Nat Rev Neurosci (2008) 3.52

Synaptic plasticity and dysconnection in schizophrenia. Biol Psychiatry (2006) 3.50

Remote control of neuronal activity with a light-gated glutamate receptor. Neuron (2007) 3.45

Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Science (2009) 3.41

Glutamate receptor dynamics in dendritic microdomains. Neuron (2008) 3.28

Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype. Nature (2000) 3.27

The interaction between Stargazin and PSD-95 regulates AMPA receptor surface trafficking. Neuron (2007) 3.25

Synaptic plasticity, memory and the hippocampus: a neural network approach to causality. Nat Rev Neurosci (2008) 3.24

Caged compounds: photorelease technology for control of cellular chemistry and physiology. Nat Methods (2007) 3.22

Synaptic plasticity: multiple forms, functions, and mechanisms. Neuropsychopharmacology (2007) 3.10

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A nomenclature for ligand-gated ion channels. Neuropharmacology (2008) 2.93

Compact biocompatible quantum dots functionalized for cellular imaging. J Am Chem Soc (2008) 2.92

Organelles and trafficking machinery for postsynaptic plasticity. Annu Rev Neurosci (2006) 2.82

Identification of a site in glutamate receptor subunits that controls calcium permeability. Science (1991) 2.53

Photoinactivation of native AMPA receptors reveals their real-time trafficking. Neuron (2005) 2.40

Photochemical control of endogenous ion channels and cellular excitability. Nat Methods (2008) 2.30

Structure and function of glutamate receptor ion channels. Annu Rev Physiol (2004) 2.29

Fluorescent labeling of recombinant proteins in living cells with FlAsH. Methods Enzymol (2000) 2.24

Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area. J Neurosci (2008) 2.15

Surface trafficking of neurotransmitter receptor: comparison between single-molecule/quantum dot strategies. J Neurosci (2007) 2.12

TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Neuron (2007) 2.07

Surface trafficking of receptors between synaptic and extrasynaptic membranes: and yet they do move! Trends Neurosci (2005) 2.07

AMPA receptor tetramerization is mediated by Q/R editing. Neuron (2003) 2.05

Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo. Nature (2003) 2.01

New concepts in synaptic biology derived from single-molecule imaging. Neuron (2008) 1.99

The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacol Rev (2005) 1.96

Presynaptic glutamate receptors: physiological functions and mechanisms of action. Nat Rev Neurosci (2008) 1.96

Molecular dissection of hippocampal theta-burst pairing potentiation. Proc Natl Acad Sci U S A (2002) 1.92

Genetically targeted chromophore-assisted light inactivation. Nat Biotechnol (2003) 1.90

Stargazin attenuates intracellular polyamine block of calcium-permeable AMPA receptors. Nat Neurosci (2007) 1.89

Synaptic transmission and plasticity in the absence of AMPA glutamate receptor GluR2 and GluR3. Neuron (2003) 1.87

Differential dependence on GluR2 expression of three characteristic features of AMPA receptors. J Neurosci (1997) 1.86

AMPA receptor trafficking and long-term potentiation. Philos Trans R Soc Lond B Biol Sci (2003) 1.85

Focal photolysis of caged glutamate produces long-term depression of hippocampal glutamate receptors. Nat Neurosci (1998) 1.78

Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents. Neuron (2007) 1.76

Molecular mechanisms controlling calcium entry through AMPA-type glutamate receptor channels. Neuron (1995) 1.76

Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement. Neuron (2001) 1.72

The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins. Pflugers Arch (2001) 1.71

Kainate receptors: pharmacology, function and therapeutic potential. Neuropharmacology (2008) 1.70

Transgenically encoded protein photoinactivation (FlAsH-FALI): acute inactivation of synaptotagmin I. Neuron (2002) 1.65

A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques. J Gen Physiol (1980) 1.59

Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice. J Physiol (2003) 1.55

Long-term potentiation of exogenous glutamate responses at single dendritic spines. Proc Natl Acad Sci U S A (2005) 1.53

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A. J Physiol (2003) 1.52

Stargazin is an AMPA receptor auxiliary subunit. Proc Natl Acad Sci U S A (2005) 1.52

It's green outside: tracking cell surface proteins with pH-sensitive GFP. Trends Neurosci (2004) 1.51

Molecular determinants of AMPA receptor subunit assembly. Trends Neurosci (2007) 1.48

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit. J Neurosci (2003) 1.43

Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins. J Pharmacol Exp Ther (1996) 1.39

AMPA receptor subunit-specific regulation by a distinct family of type II TARPs. Neuron (2008) 1.37

Reversibly caged glutamate: a photochromic agonist of ionotropic glutamate receptors. J Am Chem Soc (2007) 1.35

A single amino acid determines the subunit-specific spider toxin block of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor channels. Proc Natl Acad Sci U S A (1993) 1.29

A general approach for chemical labeling and rapid, spatially controlled protein inactivation. Proc Natl Acad Sci U S A (2004) 1.21

Desensitization properties of AMPA receptors at the cerebellar mossy fiber granule cell synapse. J Neurosci (2007) 1.20

Multiple, developmentally regulated expression mechanisms of long-term potentiation at CA1 synapses. J Neurosci (2004) 1.14

Synaptic receptor trafficking: the lateral point of view. Neuroscience (2008) 1.05

Phage display evolution of a peptide substrate for yeast biotin ligase and application to two-color quantum dot labeling of cell surface proteins. J Am Chem Soc (2007) 1.01

Critical role for TARPs in early development despite broad functional redundancy. Neuropharmacology (2008) 0.98

A subtype-selective, use-dependent inhibitor of native AMPA receptors. J Am Chem Soc (2007) 0.96

Photochemically knocking out glutamate receptors in vivo. J Am Chem Soc (2004) 0.91

Chromophore-assisted laser inactivation (CALI): probing protein function in situ with a high degree of spatial and temporal resolution. Trends Cell Biol (1996) 0.89

Polyamine toxins: development of selective ligands for ionotropic receptors. Toxicon (2005) 0.87

Flashy science: controlling neural function with light. J Neurosci (2005) 0.84

Brain plasticity and pathology in psychiatric disease: sites of action for potential therapy. Curr Opin Pharmacol (2003) 0.82

6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor. J Med Chem (2008) 0.79

Rapid photoinactivation of native AMPA receptors on live cells using ANQX. Sci STKE (2006) 0.78

A chemical-genetic approach to studying neurotrophin signaling. Neuron (2005) 2.93

Photoinactivation of native AMPA receptors reveals their real-time trafficking. Neuron (2005) 2.40

Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area. J Neurosci (2008) 2.15

TrkB kinase is required for recovery, but not loss, of cortical responses following monocular deprivation. Nat Neurosci (2008) 1.50

TrkB signaling is required for both the induction and maintenance of tissue and nerve injury-induced persistent pain. J Neurosci (2009) 0.97

A subtype-selective, use-dependent inhibitor of native AMPA receptors. J Am Chem Soc (2007) 0.96

Photochemically knocking out glutamate receptors in vivo. J Am Chem Soc (2004) 0.91

Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers. ACS Med Chem Lett (2012) 0.83

6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor. J Med Chem (2008) 0.79

Critical role of trkB receptors in reactive axonal sprouting and hyperexcitability after axonal injury. J Neurophysiol (2012) 0.79

Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. Bioorg Med Chem (2010) 0.78

Development of 5N-Bicalutamide, A High-affinity Reversible Covalent Antiandrogen. ACS Chem Biol (2017) 0.75