PubRank

Caroline Hayward

Author PubWeight™ 353.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
3 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
4 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
5 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
6 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2008 12.32
7 Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010 8.55
8 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
9 Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 2007 6.47
10 SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat Genet 2008 5.93
11 New loci associated with kidney function and chronic kidney disease. Nat Genet 2010 5.58
12 Runs of homozygosity in European populations. Am J Hum Genet 2008 5.34
13 Mutations in SOX2 cause anophthalmia. Nat Genet 2003 5.03
14 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
15 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 2013 4.71
16 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
17 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
18 Genome-wide association study identifies five loci associated with lung function. Nat Genet 2009 4.10
19 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
20 Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011 3.68
21 Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet 2010 3.55
22 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
23 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
24 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
25 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
26 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet 2012 3.04
27 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011 3.03
28 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
29 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
30 Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation 2010 2.78
31 FTO genotype is associated with phenotypic variability of body mass index. Nature 2012 2.77
32 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
33 CUBN is a gene locus for albuminuria. J Am Soc Nephrol 2011 2.70
34 Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum Mol Genet 2008 2.66
35 Variability, heritability and environmental determinants of human plasma N-glycome. J Proteome Res 2009 2.39
36 Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet 2013 2.36
37 Identification of SATB2 as the cleft palate gene on 2q32-q33. Hum Mol Genet 2003 2.25
38 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet 2012 2.12
39 Cognitive change and the APOE epsilon 4 allele. Nature 2002 2.01
40 Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet 2011 1.92
41 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet 2012 1.79
42 Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits. Hum Mol Genet 2007 1.77
43 Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet 2009 1.77
44 Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 2013 1.77
45 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
46 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
47 Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome. Int J Epidemiol 2010 1.71
48 Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012 1.68
49 3000 years of solitude: extreme differentiation in the island isolates of Dalmatia, Croatia. Eur J Hum Genet 2006 1.66
50 Genes predict village of origin in rural Europe. Eur J Hum Genet 2010 1.61
51 Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet 2013 1.52
52 Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet 2013 1.49
53 Genome-wide linkage analysis of serum creatinine in three isolated European populations. Kidney Int 2009 1.48
54 Genome-wide association study of biochemical traits in Korcula Island, Croatia. Croat Med J 2009 1.45
55 Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol 2014 1.45
56 Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation. PLoS Genet 2010 1.43
57 New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8. Hum Mol Genet 2010 1.41
58 Localising loci underlying complex trait variation using Regional Genomic Relationship Mapping. PLoS One 2012 1.34
59 Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet 2012 1.29
60 Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study. Psychol Aging 2009 1.26
61 Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet 2011 1.26
62 Common genetic variants associate with serum phosphorus concentration. J Am Soc Nephrol 2010 1.20
63 Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol 2011 1.19
64 Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5. Hum Mol Genet 2006 1.19
65 Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3. Hum Mol Genet 2012 1.18
66 Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. Hum Mol Genet 2010 1.18
67 Quantifying the increase in average human heterozygosity due to urbanisation. Eur J Hum Genet 2008 1.17
68 Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat 2011 1.17
69 Recurrence of SOX2 anophthalmia syndrome with gonosomal mosaicism in a phenotypically normal mother. Am J Med Genet A 2006 1.16
70 Evidence of inbreeding depression on human height. PLoS Genet 2012 1.16
71 Complement factor D in age-related macular degeneration. Invest Ophthalmol Vis Sci 2011 1.14
72 KLOTHO genotype and cognitive ability in childhood and old age in the same individuals. Neurosci Lett 2005 1.14
73 Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet 2012 1.14
74 A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One 2011 1.13
75 Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels. PLoS Genet 2010 1.10
76 Genome-wide association study of anthropometric traits in Korcula Island, Croatia. Croat Med J 2009 1.10
77 Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Hum Genet 2012 1.09
78 Hearing function and thresholds: a genome-wide association study in European isolated populations identifies new loci and pathways. J Med Genet 2011 1.09
79 The functional COMT polymorphism, Val 158 Met, is associated with logical memory and the personality trait intellect/imagination in a cohort of healthy 79 year olds. Neurosci Lett 2005 1.08
80 Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry 2012 1.08
81 Genome-wide association uncovers shared genetic effects among personality traits and mood states. Am J Med Genet B Neuropsychiatr Genet 2012 1.08
82 Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease. PLoS One 2010 1.07
83 Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation 2011 1.05
84 Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study. BMC Med Genet 2013 1.04
85 Comparative assessment of methods for estimating individual genome-wide homozygosity-by-descent from human genomic data. BMC Genomics 2010 1.02
86 Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet 2014 1.02
87 Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet 2013 1.02
88 Apolipoprotein e gene variability and cognitive functions at age 79: a follow-up of the Scottish mental survey of 1932. Psychol Aging 2004 1.02
89 Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. Hum Mol Genet 2013 1.01
90 Genome-wide analysis of epistasis in body mass index using multiple human populations. Eur J Hum Genet 2012 1.00
91 A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. BMC Med Genet 2010 1.00
92 Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults. Hum Mol Genet 2011 0.99
93 Variation in the uric acid transporter gene SLC2A9 and its association with AAO of Parkinson's disease. J Mol Neurosci 2010 0.99
94 Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. Behav Genet 2014 0.99
95 Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study. Behav Genet 2014 0.98
96 Variation in the uric acid transporter gene (SLC2A9) and memory performance. Hum Mol Genet 2010 0.97
97 Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. PLoS Genet 2013 0.97
98 Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration. Hum Mol Genet 2013 0.97
99 A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. BMC Genet 2007 0.95
100 No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration. Eur J Hum Genet 2011 0.94
101 The power of regional heritability analysis for rare and common variant detection: simulations and application to eye biometrical traits. Front Genet 2013 0.94
102 Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am J Epidemiol 2013 0.93
103 Uncovering networks from genome-wide association studies via circular genomic permutation. G3 (Bethesda) 2012 0.93
104 Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. Obesity (Silver Spring) 2009 0.93
105 Heritabilities of ocular biometrical traits in two croatian isolates with extended pedigrees. Invest Ophthalmol Vis Sci 2009 0.91
106 Genetic influences on oxidative stress and their association with normal cognitive ageing. Neurosci Lett 2005 0.91
107 Increased level of linkage disequilibrium in rural compared with urban communities: a factor to consider in association-study design. Am J Hum Genet 2005 0.90
108 Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome. Epigenetics 2012 0.90
109 Copy number variation across European populations. PLoS One 2011 0.89
110 Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates. PLoS One 2011 0.89
111 Inference of identity by descent in population isolates and optimal sequencing studies. Eur J Hum Genet 2013 0.89
112 Apolipoprotein E is not related to memory abilities at 70 years of age. Behav Genet 2008 0.88
113 Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet 2012 0.88
114 Genetic architecture of circulating lipid levels. Eur J Hum Genet 2011 0.88
115 DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Hum Mol Genet 2013 0.88
116 Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing. Neurosci Lett 2005 0.88
117 Mutations in HNF1A result in marked alterations of plasma glycan profile. Diabetes 2012 0.87
118 Complement factor h autoantibodies and age-related macular degeneration. Invest Ophthalmol Vis Sci 2010 0.87
119 The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis. Ann Hum Genet 2010 0.86
120 Association of existing and new candidate genes for anxiety, depression and personality traits in older people. Behav Genet 2010 0.86
121 Lack of association between polymorphisms in angiotensin-converting-enzyme and methylenetetrahydrofolate reductase genes and normal cognitive ageing in humans. Neurosci Lett 2003 0.85
122 SMAD7 variant rs4939827 is associated with colorectal cancer risk in Croatian population. PLoS One 2013 0.84
123 Biochemical characterisation of the C1QTNF5 gene associated with late-onset retinal degeneration. A genetic model of age-related macular degeneration. Adv Exp Med Biol 2006 0.84
124 Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment. Hum Mol Genet 2013 0.83
125 Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies. PLoS One 2013 0.83
126 The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability. Proc Biol Sci 2014 0.82
127 Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits. Eur J Hum Genet 2011 0.82
128 Historic, demographic, and genetic evidence for increased population frequencies of CCR5Delta32 mutation in Croatian Island isolates after lethal 15th century epidemics. Croat Med J 2009 0.82
129 Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol 2013 0.82
130 Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium. Circ Cardiovasc Genet 2015 0.82
131 Association of medication with the human plasma N-glycome. J Proteome Res 2012 0.81
132 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2008 0.81
133 Genetic variation in complement regulators and susceptibility to age-related macular degeneration. Immunobiology 2011 0.81
134 The association between galactosylation of immunoglobulin G and body mass index. Prog Neuropsychopharmacol Biol Psychiatry 2013 0.81
135 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.81
136 Genetic comparison of a Croatian isolate and CEPH European founders. Genet Epidemiol 2010 0.80
137 Can genetics aggravate the health of isolated and remote populations? The case of gout, hyperuricaemia and osteoarthritis in Dalmatia. Rural Remote Health 2013 0.79
138 Lost in transition--the Island of Susak (1951-2001). Coll Antropol 2004 0.79
139 Historic exposure to plague and present-day frequency of CCR5del32 in two isolated island communities of Dalmatia, Croatia. Croat Med J 2006 0.79
140 Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Hum Genet 2014 0.79
141 Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations. Eur J Endocrinol 2013 0.77
142 Current versus lifetime depression, APOE variation, and their interaction on cognitive performance in younger and older adults. Psychosom Med 2015 0.77
143 Heritability analysis suggests comparable genetic component of mechanical pain threshold and tolerance. Pain Med 2012 0.76
144 Does inbreeding affect N-glycosylation of human plasma proteins? Mol Genet Genomics 2011 0.76
145 Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change. Neurosci Lett 2005 0.76
146 Correction: Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation. PLoS Genet 2017 0.75
147 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
148 Mediterranean diet in the southern Croatia - does it still exist? Croat Med J 2016 0.75
149 Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts. PLoS One 2012 0.75
150 Genome-wide association studies identify genetic loci for low von Willebrand factor levels. Eur J Hum Genet 2016 0.75
151 Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet 2017 0.75
152 New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circ Cardiovasc Genet 2017 0.75
153 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.75
154 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
155 Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun 2015 0.75
156 Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet 2017 0.75
157 Validation of Surrogates of Urine Osmolality in Population Studies. Am J Nephrol 2017 0.75
158 Determinants of retinal microvascular features and their relationships in two European populations. J Hypertens 2017 0.75
159 The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape. Curr Biol 2015 0.75