PubRank

Jian'an Luan

Author PubWeight™ 300.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
3 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
4 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
5 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
6 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
7 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
8 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
9 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
10 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
11 Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents. JAMA 2012 6.43
12 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
13 The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012 4.87
14 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
15 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
16 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
17 Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000. Diabetes 2008 4.11
18 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
19 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
20 Genetic loci influencing kidney function and chronic kidney disease. Nat Genet 2010 3.75
21 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
22 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
23 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
24 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet 2011 3.18
25 Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet 2009 3.09
26 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
27 Meat consumption and prospective weight change in participants of the EPIC-PANACEA study. Am J Clin Nutr 2010 2.87
28 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
29 FTO genotype is associated with phenotypic variability of body mass index. Nature 2012 2.77
30 Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies. Am J Clin Nutr 2009 2.74
31 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
32 CUBN is a gene locus for albuminuria. J Am Soc Nephrol 2011 2.70
33 Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study. PLoS Med 2010 2.25
34 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet 2010 2.24
35 Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes 2011 2.21
36 Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene. Am J Clin Nutr 2009 2.14
37 Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action. PLoS Biol 2003 2.13
38 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
39 Type 2 diabetes is associated with a common mitochondrial variant: evidence from a population-based case-control study. Hum Mol Genet 2002 1.87
40 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
41 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
42 Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants. Am J Clin Nutr 2010 1.61
43 Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance. Cell Metab 2006 1.57
44 Longitudinal changes in weight in relation to smoking cessation in participants of the EPIC-PANACEA study. Prev Med 2011 1.55
45 Leptin-independent programming of adult body weight and adiposity in mice. Endocrinology 2011 1.49
46 Prevalence and correlates of the metabolic syndrome in a population-based sample of European youth. Am J Clin Nutr 2008 1.49
47 Digenic inheritance of severe insulin resistance in a human pedigree. Nat Genet 2002 1.36
48 Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr 2013 1.35
49 Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies. Diabetes 2007 1.35
50 Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies. Diabetes 2008 1.33
51 Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest 2010 1.33
52 A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism. Hum Mol Genet 2002 1.32
53 Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance. Diabetes 2011 1.29
54 Effect of combined movement and heart rate monitor placement on physical activity estimates during treadmill locomotion and free-living. Eur J Appl Physiol 2005 1.25
55 Adherence to the Mediterranean diet is associated with lower abdominal adiposity in European men and women. J Nutr 2009 1.22
56 Leptin predicts a worsening of the features of the metabolic syndrome independently of obesity. Obes Res 2005 1.21
57 Physical activity and gain in abdominal adiposity and body weight: prospective cohort study in 288,498 men and women. Am J Clin Nutr 2011 1.20
58 Mediterranean dietary patterns and prospective weight change in participants of the EPIC-PANACEA project. Am J Clin Nutr 2010 1.18
59 Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations. Diabetes 2003 1.01
60 Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes. Diabetes 2007 0.98
61 Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits. Diabetes 2004 0.98
62 Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. Diabetes 2004 0.94
63 Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies. Diabetes 2007 0.90
64 Typical type 2 diabetes mellitus and HFE gene mutations: a population-based case - control study. Hum Mol Genet 2003 0.88
65 Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet 2012 0.88
66 Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels. J Lipid Res 2006 0.87
67 Does physical activity energy expenditure explain the between-individual variation in plasma leptin concentrations after adjusting for differences in body composition? J Clin Endocrinol Metab 2003 0.86
68 INS VNTR class genotype and indexes of body size and obesity: population-based studies of 7,999 middle-aged men and women. Diabetes 2005 0.85
69 A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study. PLoS One 2012 0.85
70 Non-esterified fatty acid levels and physical inactivity: the relative importance of low habitual energy expenditure and cardio-respiratory fitness. Br J Nutr 2002 0.85
71 Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance. Diabetes 2005 0.84
72 Smoking and body fatness measurements: a cross-sectional analysis in the EPIC-PANACEA study. Prev Med 2009 0.84
73 Compensatory mammary growth following protein restriction during pregnancy and lactation increases early-onset mammary tumor incidence in rats. Carcinogenesis 2006 0.83
74 Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10. Hypertension 2003 0.82
75 Is there disparity between risk and incidence of cardiovascular disease after liver transplant? Transplantation 2004 0.81
76 Melanin-concentrating hormone receptor mutations and human obesity: functional analysis. Obes Res 2004 0.81
77 The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals. J Appl Physiol (1985) 2008 0.81
78 Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population. Diabetes 2003 0.80
79 PGC-1alpha genotype modifies the association of volitional energy expenditure with [OV0312]O2max. Med Sci Sports Exerc 2003 0.79
80 Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor. J Endocrinol 2004 0.76
81 Mining gene networks with application to GAW15 Problem 1. BMC Proc 2007 0.75
82 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
83 Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nat Genet 2017 0.75
84 No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits. Am J Clin Nutr 2010 0.75
85 A new sensitive and specific enzyme-linked immunosorbent assay for IgD. J Immunol Methods 2006 0.75
86 Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun 2015 0.75
87 Summary of contributions to GAW15 Group 13: candidate gene association studies. Genet Epidemiol 2007 0.75
88 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75