| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
|
N Engl J Med
|
2006
|
23.83
|
|
2
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
3
|
Genome-wide analysis of genetic loci associated with Alzheimer disease.
|
JAMA
|
2010
|
9.52
|
|
4
|
Genomewide association studies of stroke.
|
N Engl J Med
|
2009
|
5.29
|
|
5
|
Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study.
|
Circulation
|
2011
|
4.78
|
|
6
|
An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study.
|
Arch Intern Med
|
2006
|
4.23
|
|
7
|
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.
|
Lancet Neurol
|
2012
|
3.93
|
|
8
|
The amyloidogenic V122I transthyretin variant in elderly black Americans.
|
N Engl J Med
|
2015
|
3.36
|
|
9
|
Cerebral white matter lesions, retinopathy, and incident clinical stroke.
|
JAMA
|
2002
|
2.72
|
|
10
|
Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study.
|
Alzheimers Dement
|
2009
|
2.38
|
|
11
|
Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.
|
Ann Neurol
|
2011
|
2.37
|
|
12
|
Risk factors for ischemic stroke subtypes: the Atherosclerosis Risk in Communities study.
|
Stroke
|
2006
|
2.33
|
|
13
|
Twenty-two-year trends in incidence of myocardial infarction, coronary heart disease mortality, and case fatality in 4 US communities, 1987-2008.
|
Circulation
|
2012
|
2.20
|
|
14
|
Associations between inflammation and cognitive function in African Americans and European Americans.
|
J Am Geriatr Soc
|
2014
|
2.07
|
|
15
|
Cross-sectional associations of oral health measures with cognitive function in late middle-aged adults: a community-based study.
|
J Am Dent Assoc
|
2013
|
2.04
|
|
16
|
Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study.
|
Circulation
|
2011
|
1.90
|
|
17
|
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
|
Nat Genet
|
2013
|
1.82
|
|
18
|
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.
|
Nat Genet
|
2012
|
1.81
|
|
19
|
Association of plasma resistin with glomerular filtration rate and albuminuria in hypertensive adults.
|
Hypertension
|
2007
|
1.79
|
|
20
|
Common variants at 12q14 and 12q24 are associated with hippocampal volume.
|
Nat Genet
|
2012
|
1.79
|
|
21
|
Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study.
|
Stroke
|
2002
|
1.77
|
|
22
|
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.
|
Hum Mol Genet
|
2011
|
1.77
|
|
23
|
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
|
Circulation
|
2013
|
1.77
|
|
24
|
Blood pressure and white-matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) study.
|
Stroke
|
2009
|
1.70
|
|
25
|
Associations of microalbuminuria with brain atrophy and white matter hyperintensities in hypertensive sibships.
|
J Neurol Sci
|
2008
|
1.69
|
|
26
|
Relationship between circulating levels of RANTES (regulated on activation, normal T-cell expressed, and secreted) and carotid plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study.
|
Eur Heart J
|
2010
|
1.63
|
|
27
|
Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
|
PLoS Genet
|
2011
|
1.60
|
|
28
|
Sociocultural methods in the Jackson Heart Study: conceptual and descriptive overview.
|
Ethn Dis
|
2005
|
1.57
|
|
29
|
Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study.
|
Am J Epidemiol
|
2009
|
1.56
|
|
30
|
Epidemiology of pure valvular regurgitation in the large middle-aged African American cohort of the Atherosclerosis Risk in Communities study.
|
Am Heart J
|
2007
|
1.55
|
|
31
|
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.
|
Am J Hum Genet
|
2013
|
1.55
|
|
32
|
Relation between cognitive function and mortality in middle-aged adults: the atherosclerosis risk in communities study.
|
Am J Epidemiol
|
2003
|
1.54
|
|
33
|
Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort.
|
Neurology
|
2005
|
1.52
|
|
34
|
Common variants at 6q22 and 17q21 are associated with intracranial volume.
|
Nat Genet
|
2012
|
1.51
|
|
35
|
Small Brain Lesions and Incident Stroke and Mortality: A Cohort Study.
|
Ann Intern Med
|
2015
|
1.49
|
|
36
|
A comparison of serum creatinine-based methods for identifying chronic kidney disease in hypertensive individuals and their siblings.
|
Am J Hypertens
|
2006
|
1.49
|
|
37
|
Hypertension in pregnancy is a risk factor for microalbuminuria later in life.
|
J Clin Hypertens (Greenwich)
|
2013
|
1.48
|
|
38
|
Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium.
|
Stroke
|
2009
|
1.47
|
|
39
|
Risk factor profile for chronic kidney disease is similar to risk factor profile for small artery disease.
|
J Hypertens
|
2011
|
1.45
|
|
40
|
MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study.
|
Atherosclerosis
|
2009
|
1.45
|
|
41
|
25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: The NHANES-III linked mortality files.
|
Nutrition
|
2012
|
1.44
|
|
42
|
Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study.
|
J Hypertens
|
2015
|
1.44
|
|
43
|
Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.40
|
|
44
|
Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: the Atherosclerosis Risk in Communities study.
|
Circ Cardiovasc Imaging
|
2013
|
1.37
|
|
45
|
Hypertension in pregnancy as a risk factor for cardiovascular disease later in life.
|
J Hypertens
|
2010
|
1.36
|
|
46
|
Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study.
|
Vasc Med
|
2003
|
1.36
|
|
47
|
Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: the Mayo Clinic proteomic markers of arteriosclerosis study.
|
PLoS One
|
2010
|
1.34
|
|
48
|
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
|
Genet Epidemiol
|
2012
|
1.34
|
|
49
|
Heritability of leukoaraiosis in hypertensive sibships.
|
Hypertension
|
2004
|
1.29
|
|
50
|
Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age.
|
Am J Cardiol
|
2012
|
1.29
|
|
51
|
Genome-wide association of body fat distribution in African ancestry populations suggests new loci.
|
PLoS Genet
|
2013
|
1.24
|
|
52
|
Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.
|
Am J Epidemiol
|
2006
|
1.23
|
|
53
|
A whole-genome scan for stroke or myocardial infarction in family blood pressure program families.
|
Stroke
|
2008
|
1.18
|
|
54
|
Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up: the ARIC neurocognitive study.
|
Am J Epidemiol
|
2014
|
1.18
|
|
55
|
Interactions between metallopeptidase 3 polymorphism rs679620 and BMI in predicting blood pressure in African-American women with hypertension.
|
J Hypertens
|
2008
|
1.16
|
|
56
|
Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels.
|
J Comput Biol
|
2005
|
1.15
|
|
57
|
Plasma carboxy-terminal provasopressin (copeptin): a novel marker of insulin resistance and metabolic syndrome.
|
J Clin Endocrinol Metab
|
2009
|
1.11
|
|
58
|
An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program.
|
Nutr Metab (Lond)
|
2005
|
1.09
|
|
59
|
Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study.
|
J Gen Intern Med
|
2013
|
1.09
|
|
60
|
Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community-based population of middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) study.
|
Stroke
|
2003
|
1.09
|
|
61
|
Covert neurological symptoms associated with silent infarcts from midlife to older age: the Atherosclerosis Risk in Communities study.
|
Stroke
|
2012
|
1.08
|
|
62
|
Genomic susceptibility loci for brain atrophy in hypertensive sibships from the GENOA study.
|
Hypertension
|
2005
|
1.06
|
|
63
|
Troponin T and N-terminal pro-B-type natriuretic peptide: a biomarker approach to predict heart failure risk--the atherosclerosis risk in communities study.
|
Clin Chem
|
2013
|
1.06
|
|
64
|
Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project.
|
Circ Cardiovasc Genet
|
2011
|
1.06
|
|
65
|
Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study.
|
Alzheimer Dis Assoc Disord
|
2015
|
1.06
|
|
66
|
Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships.
|
J Am Soc Nephrol
|
2006
|
1.05
|
|
67
|
Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent.
|
Hepatology
|
2013
|
1.04
|
|
68
|
Migraine and white matter hyperintensities: the ARIC MRI study.
|
Neurology
|
2013
|
1.04
|
|
69
|
Admixture mapping of quantitative trait loci for blood lipids in African-Americans.
|
Hum Mol Genet
|
2009
|
1.04
|
|
70
|
Metabolomics and incident hypertension among blacks: the atherosclerosis risk in communities study.
|
Hypertension
|
2013
|
1.03
|
|
71
|
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.
|
Circ Cardiovasc Genet
|
2015
|
1.03
|
|
72
|
Vital exhaustion as a risk factor for adverse cardiac events (from the Atherosclerosis Risk In Communities [ARIC] study).
|
Am J Cardiol
|
2010
|
1.03
|
|
73
|
Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.
|
Stroke
|
2012
|
1.02
|
|
74
|
Hearing impairment and cognitive decline: a pilot study conducted within the atherosclerosis risk in communities neurocognitive study.
|
Am J Epidemiol
|
2015
|
1.01
|
|
75
|
Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study.
|
J Am Coll Cardiol
|
2009
|
1.01
|
|
76
|
A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study.
|
Atherosclerosis
|
2005
|
1.01
|
|
77
|
Association of novel risk factors with the ankle brachial index in African American and non-Hispanic white populations.
|
Mayo Clin Proc
|
2007
|
1.00
|
|
78
|
Genetics of coronary artery calcification among African Americans, a meta-analysis.
|
BMC Med Genet
|
2013
|
0.99
|
|
79
|
Orthostatic hypotension and cognitive function: the Atherosclerosis Risk in Communities Study.
|
Neuroepidemiology
|
2009
|
0.98
|
|
80
|
Hypertension in pregnancy is associated with elevated homocysteine levels later in life.
|
Am J Obstet Gynecol
|
2013
|
0.98
|
|
81
|
Is early age-related maculopathy related to cognitive function? The Atherosclerosis Risk in Communities Study.
|
Am J Ophthalmol
|
2002
|
0.97
|
|
82
|
Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.
|
Stroke
|
2014
|
0.96
|
|
83
|
Echocardiographic left ventricular mass index predicts incident stroke in African Americans: Atherosclerosis Risk in Communities (ARIC) Study.
|
Stroke
|
2007
|
0.96
|
|
84
|
Heart failure with preserved ejection fraction in African Americans: The ARIC (Atherosclerosis Risk In Communities) study.
|
JACC Heart Fail
|
2013
|
0.95
|
|
85
|
An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP).
|
Am J Hypertens
|
2006
|
0.95
|
|
86
|
Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.
|
Circ Cardiovasc Genet
|
2012
|
0.94
|
|
87
|
Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.
|
PLoS One
|
2011
|
0.94
|
|
88
|
The predictive value of left atrial size for incident ischemic stroke and all-cause mortality in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study.
|
Stroke
|
2008
|
0.94
|
|
89
|
Risk of intraparenchymal hemorrhage with magnetic resonance imaging-defined leukoaraiosis and brain infarcts.
|
Ann Neurol
|
2012
|
0.94
|
|
90
|
Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study.
|
Mov Disord
|
2015
|
0.93
|
|
91
|
Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study.
|
BMC Med Genomics
|
2009
|
0.93
|
|
92
|
Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study.
|
Eur J Heart Fail
|
2010
|
0.93
|
|
93
|
Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.
|
Hypertension
|
2007
|
0.92
|
|
94
|
Cardiovascular biomarkers and subclinical brain disease in the atherosclerosis risk in communities study.
|
Stroke
|
2013
|
0.91
|
|
95
|
Associations of candidate biomarkers of vascular disease with the ankle-brachial index and peripheral arterial disease.
|
Am J Hypertens
|
2013
|
0.90
|
|
96
|
Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study).
|
Am J Cardiol
|
2007
|
0.90
|
|
97
|
Evaluation of microarray-based DNA methylation measurement using technical replicates: the Atherosclerosis Risk In Communities (ARIC) Study.
|
BMC Bioinformatics
|
2014
|
0.90
|
|
98
|
Copy number variations associated with obesity-related traits in African Americans: a joint analysis between GENOA and HyperGEN.
|
Obesity (Silver Spring)
|
2012
|
0.89
|
|
99
|
Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program.
|
Hum Genet
|
2006
|
0.89
|
|
100
|
Biomarkers associated with pulse pressure in African-Americans and non-Hispanic whites.
|
Am J Hypertens
|
2011
|
0.89
|
|
101
|
Association of serum myeloperoxidase with the ankle-brachial index and peripheral arterial disease.
|
Vasc Med
|
2009
|
0.89
|
|
102
|
Genomic susceptibility Loci for brain atrophy, ventricular volume, and leukoaraiosis in hypertensive sibships.
|
Arch Neurol
|
2009
|
0.88
|
|
103
|
Novel genomic loci influencing plasma homocysteine levels.
|
Stroke
|
2006
|
0.88
|
|
104
|
Retinal microvascular abnormalities predict progression of brain microvascular disease: an atherosclerosis risk in communities magnetic resonance imaging study.
|
Stroke
|
2014
|
0.88
|
|
105
|
Heritability and genetic linkage of left ventricular mass, systolic and diastolic function in hypertensive African Americans (From the GENOA Study).
|
Am J Hypertens
|
2010
|
0.88
|
|
106
|
The metabolic syndrome and cognitive decline in the Atherosclerosis Risk in Communities study (ARIC).
|
Dement Geriatr Cogn Disord
|
2014
|
0.88
|
|
107
|
Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study.
|
Circ Cardiovasc Genet
|
2012
|
0.87
|
|
108
|
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.
|
BMC Med Genet
|
2009
|
0.87
|
|
109
|
Hypertension status, treatment, and control among spousal pairs in a middle-aged adult cohort.
|
Am J Epidemiol
|
2011
|
0.87
|
|
110
|
Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the atherosclerosis risk in communities study.
|
Cerebrovasc Dis
|
2008
|
0.87
|
|
111
|
Hypertension in pregnancy is a risk factor for peripheral arterial disease decades after pregnancy.
|
Atherosclerosis
|
2013
|
0.86
|
|
112
|
Association of serum osteoprotegerin with ankle-brachial index and urine albumin: creatinine ratio in African-Americans and non-Hispanic whites.
|
Atherosclerosis
|
2009
|
0.85
|
|
113
|
Heart rate variability and the risk of Parkinson disease: The Atherosclerosis Risk in Communities study.
|
Ann Neurol
|
2015
|
0.84
|
|
114
|
Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.
|
Am J Hypertens
|
2008
|
0.84
|
|
115
|
Mid-regional pro-adrenomedullin is associated with pulse pressure, left ventricular mass, and albuminuria in African Americans with hypertension.
|
Am J Hypertens
|
2009
|
0.84
|
|
116
|
Type 2 diabetes and cognitive decline over 14 years in middle-aged African Americans and whites: the ARIC Brain MRI Study.
|
Neuroepidemiology
|
2014
|
0.84
|
|
117
|
Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study.
|
Atherosclerosis
|
2011
|
0.84
|
|
118
|
Family-based association study of matrix metalloproteinase-3 and -9 haplotypes with susceptibility to ischemic white matter injury.
|
Hum Genet
|
2006
|
0.83
|
|
119
|
Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study.
|
Neurology
|
2012
|
0.83
|
|
120
|
SNP-SNP interactions dominate the genetic architecture of candidate genes associated with left ventricular mass in African-Americans of the GENOA study.
|
BMC Med Genet
|
2010
|
0.83
|
|
121
|
Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study.
|
Circ Cardiovasc Genet
|
2015
|
0.83
|
|
122
|
Plasma midregional pro-atrial natriuretic peptide is associated with blood pressure indices and hypertension severity in adults with hypertension.
|
Am J Hypertens
|
2009
|
0.82
|
|
123
|
Hypertension in pregnancy is associated with elevated C-reactive protein levels later in life.
|
J Hypertens
|
2013
|
0.82
|
|
124
|
Biomarkers of left ventricular hypertrophy and remodeling in blacks.
|
Hypertension
|
2011
|
0.82
|
|
125
|
Association of soluble cell adhesion molecules with ankle-brachial index in a biethnic cohort of predominantly hypertensive individuals.
|
Clin Chem
|
2008
|
0.81
|
|
126
|
Ethnic differences in low-density lipoprotein particle size in hypertensive adults.
|
J Clin Lipidol
|
2007
|
0.80
|
|
127
|
Vital exhaustion and retinal microvascular changes in cardiovascular disease: atherosclerosis risk in communities study.
|
Psychosom Med
|
2008
|
0.80
|
|
128
|
Relation of plasma midregional proatrial natriuretic peptide to target organ damage in adults with systemic hypertension.
|
Am J Cardiol
|
2009
|
0.80
|
|
129
|
Impact of long-term measures of glucose and blood pressure on the retinal microvasculature.
|
Atherosclerosis
|
2012
|
0.80
|
|
130
|
Genome scan for hypertension in nonobese African Americans: the National Heart, Lung, and Blood Institute Family Blood Pressure Program.
|
Am J Hypertens
|
2004
|
0.80
|
|
131
|
Is early age-related macular degeneration associated with cerebral MRI changes? The Atherosclerosis Risk in Communities study.
|
Am J Ophthalmol
|
2006
|
0.79
|
|
132
|
Physical activity and subclinical MRI cerebral infarcts: the ARIC Study.
|
J Neurol Sci
|
2009
|
0.79
|
|
133
|
Genome-wide linkage analysis for uric acid in families enriched for hypertension.
|
Nephrol Dial Transplant
|
2009
|
0.79
|
|
134
|
Association between birthweight and cognitive function in middle age: the atherosclerosis risk in communities study.
|
Ann Epidemiol
|
2011
|
0.78
|
|
135
|
Association of serum osteoprotegerin with left ventricular mass in African American adults with hypertension.
|
Am J Hypertens
|
2010
|
0.78
|
|
136
|
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J Am Soc Hypertens
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J Am Coll Cardiol
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Community Dent Oral Epidemiol
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Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations.
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The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study.
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The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity.
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