Published in Genes Cells on January 19, 2010
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev (2011) 5.60
The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell (2010) 5.06
PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis. Curr Opin Struct Biol (2013) 1.23
Reprogramming cellular events by poly(ADP-ribose)-binding proteins. Mol Aspects Med (2012) 1.11
Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR). J Biol Chem (2010) 0.99
CHFR is important for the first wave of ubiquitination at DNA damage sites. Nucleic Acids Res (2012) 0.93
Readers of poly(ADP-ribose): designed to be fit for purpose. Nucleic Acids Res (2015) 0.87
HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity. Mol Cell (2016) 0.83
Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling. Mol Aspects Med (2013) 0.81
Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins. Methods Mol Biol (2011) 0.80
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature (2008) 3.62
Spatial and temporal cellular responses to single-strand breaks in human cells. Mol Cell Biol (2003) 2.70
In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Proc Natl Acad Sci U S A (2004) 2.59
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain. EMBO Rep (2009) 2.50
Childhood neglect is associated with reduced corpus callosum area. Biol Psychiatry (2004) 2.26
Crystal structure of thymine DNA glycosylase conjugated to SUMO-1. Nature (2005) 2.11
High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. Nature (2009) 2.06
Treatment with methotrexate and low-dose corticosteroids in sarcoidosis patients with cardiac lesions. Intern Med (2014) 2.00
Structure of the UBA domain of Dsk2p in complex with ubiquitin molecular determinants for ubiquitin recognition. Structure (2005) 1.90
A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue. J Biol Chem (2002) 1.89
MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. J Exp Med (2005) 1.80
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Mol Cell (2006) 1.79
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proc Natl Acad Sci U S A (2008) 1.73
In vivo recruitment of XPC to UV-induced cyclobutane pyrimidine dimers by the DDB2 gene product. J Biol Chem (2003) 1.73
Protein structure determination in living cells by in-cell NMR spectroscopy. Nature (2009) 1.71
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc Natl Acad Sci U S A (2009) 1.65
A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses. EMBO J (2007) 1.65
DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair. J Biol Chem (2005) 1.63
Accumulation of Werner protein at DNA double-strand breaks in human cells. J Cell Sci (2005) 1.59
The ACF1 complex is required for DNA double-strand break repair in human cells. Mol Cell (2010) 1.57
The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions. DNA Repair (Amst) (2005) 1.57
Measurement of internal body time by blood metabolomics. Proc Natl Acad Sci U S A (2009) 1.56
Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant mice. Genes Dev (2002) 1.56
HMGB1 is a cofactor in mammalian base excision repair. Mol Cell (2007) 1.49
Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9. Mol Endocrinol (2004) 1.47
A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell. Nucleic Acids Res (2008) 1.47
Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains. Genes Cells (2004) 1.45
Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95. J Mol Biol (2003) 1.45
The structure and binding mode of interleukin-18. Nat Struct Biol (2003) 1.42
Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. Nat Genet (2012) 1.42
RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair. Mol Cell Biol (2007) 1.41
Structure of the ubiquitin-interacting motif of S5a bound to the ubiquitin-like domain of HR23B. J Biol Chem (2003) 1.40
Powerful skin cancer protection by a CPD-photolyase transgene. Curr Biol (2005) 1.39
Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle. Mol Cell Biol (2005) 1.37
Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei. Curr Biol (2002) 1.36
Crystal structure of the RuvA-RuvB complex: a structural basis for the Holliday junction migrating motor machinery. Mol Cell (2002) 1.35
The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells. Mol Cell (2011) 1.34
DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients. Proc Natl Acad Sci U S A (2009) 1.34
Human DNA polymerase iota protects cells against oxidative stress. EMBO J (2008) 1.31
Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols. EMBO J (2002) 1.28
Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1. Nat Struct Mol Biol (2012) 1.27
Emergence and spread of B2-ST131-O25b, B2-ST131-O16 and D-ST405 clonal groups among extended-spectrum-β-lactamase-producing Escherichia coli in Japan. J Antimicrob Chemother (2012) 1.24
Structure of the small ubiquitin-like modifier (SUMO)-interacting motif of MBD1-containing chromatin-associated factor 1 bound to SUMO-3. J Biol Chem (2008) 1.23
Intracellular phosphate serves as a signal for the regulation of the PHO pathway in Saccharomyces cerevisiae. J Biol Chem (2004) 1.22
Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1. Proc Natl Acad Sci U S A (2012) 1.22
Replication-dependent and -independent responses of RAD18 to DNA damage in human cells. J Biol Chem (2006) 1.21
Paramagnetic relaxation-based 19f MRI probe to detect protease activity. J Am Chem Soc (2007) 1.21
BLM is an early responder to DNA double-strand breaks. Biochem Biophys Res Commun (2006) 1.21
Methylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatin. Proc Natl Acad Sci U S A (2003) 1.21
Recruitment of mismatch repair proteins to the site of DNA damage in human cells. J Cell Sci (2008) 1.19
Plc1p, Arg82p, and Kcs1p, enzymes involved in inositol pyrophosphate synthesis, are essential for phosphate regulation and polyphosphate accumulation in Saccharomyces cerevisiae. J Biol Chem (2005) 1.18
Circadian behavioral rhythms in Cry1/Cry2 double-deficient mice induced by methamphetamine. J Biol Rhythms (2008) 1.17
Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging. Nat Chem (2009) 1.16
Werner syndrome protein interacts functionally with translesion DNA polymerases. Proc Natl Acad Sci U S A (2007) 1.15
Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku80. Mol Cell Biol (2008) 1.15
DNA single-strand break repair is impaired in aprataxin-related ataxia. Ann Neurol (2007) 1.14
Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells. DNA Repair (Amst) (2004) 1.14
UV light-induced DNA damage and tolerance for the survival of nucleotide excision repair-deficient human cells. J Biol Chem (2004) 1.13
Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6). J Biol Chem (2013) 1.12
Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells. Infect Immun (2002) 1.12
In-cell NMR spectroscopy of proteins inside Xenopus laevis oocytes. J Biomol NMR (2006) 1.10
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1. Oncogene (2005) 1.10
Enhanced repair of cyclobutane pyrimidine dimers and improved UV resistance in photolyase transgenic mice. EMBO J (2002) 1.09
Prognostic value of reduced left ventricular ejection fraction at start of hemodialysis therapy on cardiovascular and all-cause mortality in end-stage renal disease patients. Clin J Am Soc Nephrol (2010) 1.09
Crystal structure of SUMO-3-modified thymine-DNA glycosylase. J Mol Biol (2006) 1.09
Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities. J Mol Biol (2002) 1.08
Dissociated linkage of cytokine-inducing activity and cytotoxicity to different domains of listeriolysin O from Listeria monocytogenes. Infect Immun (2002) 1.07
DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells. DNA Repair (Amst) (2005) 1.06
Solution structure of the fibronectin type III domain from Bacillus circulans WL-12 chitinase A1. J Biol Chem (2001) 1.06
The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA. J Biol Chem (2013) 1.05
DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst) (2009) 1.05
Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin. J Biol Chem (2011) 1.04
Longitudinal study of airway dimensions in chronic obstructive pulmonary disease using computed tomography. Respirology (2008) 1.04