Published in Cancer Res on January 26, 2010
Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro Oncol (2012) 1.96
Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol (2012) 1.93
Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer. J Appl Physiol (1985) (2012) 1.08
Inhibition of angiogenesis- and inflammation-inducing factors in human colon cancer cells in vitro and in ovo by free and nanoparticle-encapsulated redox dye, DCPIP. J Nanobiotechnology (2010) 0.88
Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-α and dendritic cell vaccine. PLoS One (2012) 0.86
Overexpression of Ras homologous C (RhoC) induces malignant transformation of hepatocytes in vitro and in nude mouse xenografts. PLoS One (2013) 0.86
Pleiotrophin is a potential colorectal cancer prognostic factor that promotes VEGF expression and induces angiogenesis in colorectal cancer. Int J Colorectal Dis (2011) 0.80
METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells. BMC Cancer (2016) 0.77
The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A (2004) 26.56
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature (2009) 11.27
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Copy number variation and selection during reprogramming to pluripotency. Nature (2011) 8.24
The knockout mouse project. Nat Genet (2004) 7.80
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell (2010) 7.51
Autocrine VEGF signaling is required for vascular homeostasis. Cell (2007) 7.37
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis (2002) 6.11
Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci U S A (2002) 5.54
Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res (2005) 4.08
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals. Genesis (2004) 3.80
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell (2005) 3.74
Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal. BMC Biotechnol (2002) 2.97
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein. Cell (2004) 2.91
Niche-mediated control of human embryonic stem cell self-renewal and differentiation. EMBO J (2007) 2.91
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell (2011) 2.89
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
Developmental and adult phenotyping directly from mutant embryonic stem cells. Proc Natl Acad Sci U S A (2007) 2.61
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2. Mol Cell Biol (2006) 2.58
Oct4 is required for primordial germ cell survival. EMBO Rep (2004) 2.56
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature (2013) 2.49
Platelets actively sequester angiogenesis regulators. Blood (2008) 2.47
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell (2008) 2.31
Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase. Nat Biotechnol (2003) 2.28
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling. Dev Biol (2003) 2.24
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis. Cell Metab (2013) 2.21
Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metab (2007) 2.12
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol (2006) 2.10
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
Transposon-mediated genome manipulation in vertebrates. Nat Methods (2009) 1.96
A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet (2004) 1.87
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development (2005) 1.82
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development (2003) 1.80
Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity. Blood (2005) 1.80
Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell (2012) 1.79
Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications. Blood (2011) 1.76
Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells. Stem Cells (2008) 1.69
Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J (2009) 1.68
Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. Genes Dev (2004) 1.65
Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development (2002) 1.63
Elevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells. Stem Cells (2012) 1.62
Functional immobilization of signaling proteins enables control of stem cell fate. Nat Methods (2008) 1.52
Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos. PLoS One (2010) 1.47
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage. Cancer Cell (2010) 1.47
Overexpression of SOCS-2 and SOCS-3 genes reverses erythroid overgrowth and IGF-I hypersensitivity of primary polycythemia vera (PV) cells. Leuk Lymphoma (2007) 1.42
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell (2009) 1.36
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells. Nucleic Acids Res (2009) 1.35
Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy. Cancer Res (2005) 1.31
Concise review: Embryonic stem cells versus induced pluripotent stem cells: the game is on. Stem Cells (2012) 1.28
The miR-17-92 cluster expands multipotent hematopoietic progenitors whereas imbalanced expression of its individual oncogenic miRNAs promotes leukemia in mice. Blood (2012) 1.27
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival. J Neurosci (2006) 1.24
Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin Cancer Res (2004) 1.23
Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures. Nat Methods (2012) 1.23
Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model. Cancer Res (2003) 1.20
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. EMBO J (2003) 1.19
Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland. Stem Cells Dev (2010) 1.17
Induced pluripotent stem cell lines derived from equine fibroblasts. Stem Cell Rev (2011) 1.17
Impaired intervertebral disc formation in the absence of Jun. Development (2003) 1.15
Donor hematopoietic cells from transgenic mice that express GFP are immunogenic in immunocompetent recipients. Hematology (2005) 1.14
Spectrums of opportunistic infections and malignancies in HIV-infected patients in tertiary care hospital, China. PLoS One (2013) 1.12
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol (2009) 1.12
The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis. Blood (2010) 1.12
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin. Development (2012) 1.11
ARS2 is a conserved eukaryotic gene essential for early mammalian development. Mol Cell Biol (2007) 1.10
Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase. Oncogene (2004) 1.10
Interview: Virus-free induction of induced pluripotent stem cells. Regen Med (2009) 1.08
Zonadhesin is essential for species specificity of sperm adhesion to the egg zona pellucida. J Biol Chem (2010) 1.08
Transgenic targeting with regulatory elements of the human CD34 gene. Blood (2002) 1.08
Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis. Biochem Biophys Res Commun (2008) 1.07
Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors. EMBO J (2003) 1.04
The roles of microRNAs in tumorigenesis and angiogenesis. Int J Physiol Pathophysiol Pharmacol (2010) 1.03
VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. EMBO Mol Med (2013) 1.00
Identification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance. Blood (2009) 1.00
Development and application of a loop-mediated isothermal amplification method on rapid detection Escherichia coli O157 strains from food samples. Mol Biol Rep (2009) 1.00
Simple piggyBac transposon-based mammalian cell expression system for inducible protein production. Proc Natl Acad Sci U S A (2013) 0.98
Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells (2008) 0.98
The splenic microenvironment is a source of proangiogenesis/inflammatory mediators accelerating the expansion of murine erythroleukemic cells. Blood (2005) 0.98
Friend virus-induced erythroleukemias: a unique and well-defined mouse model for the development of leukemia. Anticancer Res (2003) 0.96
Comment on "Failure of bone marrow cells to transdifferentiate into neural cells in vivo". Science (2003) 0.96
Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting. J Clin Invest (2013) 0.96
Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis. Biotechnol Bioeng (2003) 0.95
Alcian blue staining of the mouse fetal cartilaginous skeleton. Cold Spring Harb Protoc (2009) 0.94
The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation. Cell Rep (2013) 0.93
SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis. Development (2004) 0.93
Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms. Blood (2010) 0.93
Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways. PLoS One (2012) 0.91
Gastric acid secretion in L-histidine decarboxylase-deficient mice. Gastroenterology (2002) 0.91
c-Myb-dependent smooth muscle cell differentiation. Circ Res (2008) 0.91
Upregulated microRNA-155 expression in peripheral blood mononuclear cells and fibroblast-like synoviocytes in rheumatoid arthritis. Clin Dev Immunol (2013) 0.91
Mice with Cre recombinase activatable PDGF-C expression. Genesis (2002) 0.91
Alizarin red staining of post-natal bone in mouse. Cold Spring Harb Protoc (2009) 0.90
The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway. Stem Cells Dev (2012) 0.90
Stem cell therapy for the kidney: a cautionary tale. J Am Soc Nephrol (2010) 0.90
"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells. Mamm Genome (2005) 0.90
Screening a phage display library for a novel FGF8b-binding peptide with anti-tumor effect on prostate cancer. Exp Cell Res (2013) 0.89