PubRank

Mauro Perretti

Author PubWeight™ 170.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Resolution of inflammation: state of the art, definitions and terms. FASEB J 2007 5.12
2 Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov 2004 5.08
3 Role of the immune system in chronic pain. Nat Rev Neurosci 2005 4.10
4 Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 2009 3.27
5 Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J 2002 2.13
6 Resolution of inflammation: an integrated view. EMBO Mol Med 2013 2.01
7 Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2-26). J Immunol 2005 1.68
8 Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol 2012 1.67
9 Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. Blood 2005 1.62
10 Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. Blood 2008 1.61
11 Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms. Blood 2003 1.60
12 Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J Clin Invest 2012 1.57
13 Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors. J Biol Chem 2006 1.55
14 Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. J Immunol 2011 1.52
15 Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis. J Immunol 2006 1.52
16 Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A 2013 1.49
17 Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol 2005 1.43
18 The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner. J Biol Chem 2002 1.39
19 Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis. Arthritis Rheum 2004 1.39
20 NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Proc Natl Acad Sci U S A 2002 1.36
21 Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo. J Immunol 2004 1.31
22 A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils. FASEB J 2003 1.30
23 Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages. J Immunol 2009 1.30
24 Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists. Pharmacol Ther 2010 1.29
25 Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation. Am J Pathol 2005 1.27
26 Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. Proc Natl Acad Sci U S A 2004 1.26
27 Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. Eur J Immunol 2010 1.26
28 FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J 2010 1.23
29 Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. FASEB J 2007 1.22
30 Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight. Biochem Pharmacol 2003 1.21
31 A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation. Am J Pathol 2003 1.20
32 Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J Immunol 2008 1.18
33 Melanocortin receptor signaling in RAW264.7 macrophage cell line. Peptides 2005 1.16
34 Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis Rheum 2002 1.15
35 Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow. J Leukoc Biol 2008 1.14
36 Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. J Immunol 2003 1.13
37 Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest 2015 1.13
38 Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking. FASEB J 2007 1.12
39 Ligand-specific glucocorticoid receptor activation in human platelets. Blood 2005 1.12
40 Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function. FASEB J 2007 1.11
41 Annexin-1 modulates T-cell activation and differentiation. Blood 2006 1.10
42 Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3. J Biol Chem 2007 1.10
43 Melanocortin 3 receptors control crystal-induced inflammation. FASEB J 2006 1.08
44 An overview of the effects of annexin 1 on cells involved in the inflammatory process. Mem Inst Oswaldo Cruz 2005 1.08
45 The peritoneal tumour microenvironment of high-grade serous ovarian cancer. J Pathol 2012 1.07
46 Interleukin 17 sustains rather than induces inflammation. Biochem Pharmacol 2008 1.06
47 Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis. FASEB J 2010 1.06
48 Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. EMBO Mol Med 2013 1.05
49 Inhibitory effects of TSG-6 Link module on leukocyte-endothelial cell interactions in vitro and in vivo. Microcirculation 2004 1.05
50 Formyl-peptide receptor is not involved in the protection afforded by annexin 1 in murine acute myocardial infarct. FASEB J 2004 1.05
51 Aspirin and steroids: new mechanistic findings and avenues for drug discovery. Curr Opin Pharmacol 2005 1.04
52 Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice. PLoS One 2013 1.04
53 The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties. Am J Pathol 2011 1.03
54 Endogenous galectins and the control of the host inflammatory response. J Endocrinol 2009 1.03
55 Annexin-1 modulates repair of gastric mucosal injury. Am J Physiol Gastrointest Liver Physiol 2008 1.03
56 Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3. Cell Biol Int 2006 1.02
57 Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics 2013 1.02
58 Regulation of leukocyte-endothelial interactions by glucocorticoids. Ann N Y Acad Sci 2002 1.02
59 Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. Arthritis Rheum 2011 1.01
60 Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor. J Immunol 2013 1.00
61 Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients. Mol Cell Proteomics 2005 1.00
62 Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature. J Immunol 2011 1.00
63 Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. Eur J Immunol 2007 0.99
64 Activation of PPARbeta/delta inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release. J Leukoc Biol 2009 0.99
65 Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation. Am J Pathol 2008 0.99
66 Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB J 2008 0.98
67 Up-regulation of Annexin-A1 and lipoxin A(4) in individuals with ulcerative colitis may promote mucosal homeostasis. PLoS One 2012 0.98
68 Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. Eur J Pharmacol 2009 0.98
69 Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow. J Pharmacol Exp Ther 2007 0.98
70 A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood 2013 0.98
71 A role for MC3R in modulating lung inflammation. Pulm Pharmacol Ther 2008 0.97
72 Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis. Proc Natl Acad Sci U S A 2002 0.97
73 Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature. Blood 2010 0.97
74 Chemokines as novel therapeutic targets in inflammatory diseases. Biochem Pharmacol 2002 0.96
75 The impact of endogenous annexin A1 on glucocorticoid control of inflammatory arthritis. Ann Rheum Dis 2012 0.96
76 Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate. Methods Enzymol 2010 0.96
77 Impaired phagocytic mechanism in annexin 1 null macrophages. Br J Pharmacol 2006 0.96
78 A novel peptide agonist of formyl-peptide receptor-like 1 (ALX) displays anti-inflammatory and cardioprotective effects. J Pharmacol Exp Ther 2008 0.95
79 A novel effect for annexin 1-derived peptide ac2-26: reduction of allergic inflammation in the rat. J Pharmacol Exp Ther 2005 0.95
80 Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities. J Med Chem 2007 0.94
81 Stromal cell-derived factor 1 (CXCL12) induces human cell migration into human lymph nodes transplanted into SCID mice. J Immunol 2002 0.94
82 Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes. Biochem Biophys Res Commun 2006 0.94
83 Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol 2010 0.94
84 [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse). Mol Pharmacol 2006 0.93
85 A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5. J Immunol 2007 0.93
86 IL-17A increases ADP-induced platelet aggregation. Biochem Biophys Res Commun 2011 0.92
87 Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease. J Mol Cell Cardiol 2012 0.92
88 Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function. Obesity (Silver Spring) 2013 0.91
89 The effect of galectins on leukocyte trafficking in inflammation: sweet or sour? Ann N Y Acad Sci 2012 0.91
90 Attenuation of plasma annexin A1 in human obesity. FASEB J 2012 0.91
91 An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse. Lab Invest 2010 0.91
92 Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo. J Pharmacol Exp Ther 2011 0.90
93 In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation. J Immunol 2005 0.90
94 Stimulus-dependent specificity for annexin 1 inhibition of the inflammatory nociceptive response: the involvement of the receptor for formylated peptides. Pain 2004 0.90
95 Controlling inflammation: a fat chance? J Exp Med 2005 0.89
96 Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages. Br J Pharmacol 2004 0.89
97 Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling. J Biol Chem 2012 0.89
98 Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J 2008 0.88
99 Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. Am J Pathol 2011 0.88
100 Modulation of experimental autoimmune encephalomyelitis by endogenous annexin A1. J Neuroinflammation 2009 0.88
101 Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides. J Pharmacol Exp Ther 2003 0.88
102 Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow. FASEB J 2011 0.87
103 Prednisolone exerts exquisite inhibitory properties on platelet functions. Biochem Pharmacol 2012 0.87
104 Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J 2011 0.87
105 Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. Cell Cycle 2010 0.87
106 Inhibitory control of TGF-beta1 on the activation of Rap1, CD11b, and transendothelial migration of leukocytes. FASEB J 2005 0.87
107 Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets. Int Immunopharmacol 2010 0.86
108 Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis. Am J Pathol 2007 0.85
109 Actions of translocator protein ligands on neutrophil adhesion and motility induced by G-protein coupled receptor signaling. Biochem Biophys Res Commun 2011 0.85
110 Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression. Circ Res 2013 0.85
111 Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. J Clin Invest 2014 0.85
112 Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol 2012 0.84
113 CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway. Am J Pathol 2010 0.84
114 MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct. J Leukoc Biol 2004 0.84
115 Enhanced neutrophil expression of annexin-1 in coronary artery disease. Metabolism 2009 0.83
116 Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes. Arterioscler Thromb Vasc Biol 2011 0.83
117 Control of myeloid cell trafficking in resolution. J Innate Immun 2013 0.83
118 Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. Hepatology 2014 0.83
119 Endogenous galectin-1 exerts tonic inhibition on experimental arthritis. J Immunol 2013 0.82
120 An isocratic HPLC method for the quantitation of eicosanoids in human platelets. Biomed Chromatogr 2004 0.82
121 Downstream gene activation of the receptor ALX by the agonist annexin A1. PLoS One 2010 0.82
122 Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. J Immunol 2003 0.82
123 Melanocortin receptors as novel effectors of macrophage responses in inflammation. Front Immunol 2011 0.82
124 Genetic ablation of the fpr1 gene confers protection from smoking-induced lung emphysema in mice. Am J Respir Cell Mol Biol 2012 0.82
125 Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling. PLoS One 2013 0.82
126 Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol 2011 0.82
127 Butanol-extracted lipoteichoic acid induces in vivo leukocyte adhesion. Biochem Biophys Res Commun 2007 0.81
128 Molecular engineering of short half-life small peptides (VIP, αMSH and γ₃MSH) fused to latency-associated peptide results in improved anti-inflammatory therapeutics. Ann Rheum Dis 2011 0.81
129 Annexin 1 localisation in tissue eosinophils as detected by electron microscopy. Mediators Inflamm 2002 0.81
130 Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis. BMC Immunol 2011 0.81
131 Antiflammin-2 activates the human formyl-peptide receptor like 1. ScientificWorldJournal 2006 0.81
132 The distinct alterations produced in cardiovascular functions by prednisolone and nitro-prednisolone (NCX-1015) in the rat highlight a causal role for endothelin-1. J Pharmacol Exp Ther 2004 0.81
133 Melanocortin control of cell trafficking in vascular inflammation. Adv Exp Med Biol 2010 0.81
134 Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep 2013 0.81
135 Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression. Mediators Inflamm 2013 0.80
136 An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis. J Control Release 2013 0.80
137 Gapdh gene expression is modulated by inflammatory arthritis and is not suitable for qPCR normalization. Inflammation 2014 0.80
138 Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids. Peptides 2010 0.79
139 The role of omega-3 derived resolvins in arthritis. Curr Opin Pharmacol 2013 0.79
140 Annexin-1 is an endogenous gastroprotective factor against indomethacin-induced damage. Am J Physiol Gastrointest Liver Physiol 2004 0.79
141 Editorial: to resolve or not to resolve: annexin A1 pushes resolution on track. J Leukoc Biol 2012 0.79
142 Synthesis of nitro esters of prednisolone, new compounds combining pharmacological properties of both glucocorticoids and nitric oxide. J Med Chem 2004 0.79
143 AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice. J Cell Mol Med 2014 0.78
144 Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4- CD8- T cells. Autoimmunity 2010 0.78
145 Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides. Int J Inflam 2013 0.78
146 Human RCAN3 gene expression and cell growth in endothelial cells. Int J Mol Med 2010 0.78
147 A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones. FASEB J 2002 0.78
148 Uneven modulation of the annexin 1 system in osteoblast-like cells by dexamethasone. Biochem Biophys Res Commun 2007 0.78
149 The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis. PLoS One 2013 0.78
150 Role of melanocortin receptors in the regulation of gouty inflammation. Curr Rheumatol Rep 2011 0.77
151 Novel pathways in the yin-yang of immunomodulation. Curr Opin Pharmacol 2013 0.77
152 Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis. Arterioscler Thromb Vasc Biol 2009 0.77
153 The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage. Eur J Pharmacol 2006 0.77
154 The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse. Microcirculation 2010 0.76
155 Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis. J Leukoc Biol 2010 0.76
156 Annexin-A1 protein and its relationship to cortisol in human saliva. Psychoneuroendocrinology 2012 0.75
157 Effects of cyclooxygenase-1/cyclooxygenase-2 inhibition on leukocyte/endothelial cell interactions in the rat mesentery. Eur J Pharmacol 2002 0.75
158 Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis. Shock 2017 0.75
159 Selective inhibitors of Kv11.1 regulate IL-6 expression by macrophages in response to TLR/IL-1R ligands. ScientificWorldJournal 2010 0.75
160 Acute myocardial infarction in streptozotocin-induced hyperglycaemic rats: protection by a carbon monoxide-releasing molecule (CORM-3). Naunyn Schmiedebergs Arch Pharmacol 2011 0.75
161 Distinct localization of T cell Agrin during antigen presentation--evidence for the expression of Agrin receptor(s) in antigen-presenting cells. FEBS J 2012 0.75