Published in BMC Bioinformatics on January 27, 2010
Polygenic modeling with bayesian sparse linear mixed models. PLoS Genet (2013) 2.59
fastSTRUCTURE: variational inference of population structure in large SNP data sets. Genetics (2014) 2.13
The Bayesian lasso for genome-wide association studies. Bioinformatics (2010) 1.99
Efficient Bayesian mixed-model analysis increases association power in large cohorts. Nat Genet (2015) 1.79
A Bayesian antedependence model for whole genome prediction. Genetics (2011) 1.45
Learning genetic epistasis using Bayesian network scoring criteria. BMC Bioinformatics (2011) 1.21
A Bayesian method and its variational approximation for prediction of genomic breeding values in multiple traits. BMC Bioinformatics (2013) 1.19
Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's disease. PLoS Genet (2013) 1.14
Estimation of quantitative trait locus effects with epistasis by variational Bayes algorithms. Genetics (2011) 1.07
PUMA: a unified framework for penalized multiple regression analysis of GWAS data. PLoS Comput Biol (2013) 1.00
Mining pure, strict epistatic interactions from high-dimensional datasets: ameliorating the curse of dimensionality. PLoS One (2012) 0.97
A Bayesian nonparametric approach for mapping dynamic quantitative traits. Genetics (2013) 0.93
A variational Bayes discrete mixture test for rare variant association. Genet Epidemiol (2014) 0.92
A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging. Bioinformatics (2012) 0.91
Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control. BMC Bioinformatics (2012) 0.91
Bayesian variable selection in searching for additive and dominant effects in genome-wide data. PLoS One (2012) 0.90
Network-guided sparse regression modeling for detection of gene-by-gene interactions. Bioinformatics (2013) 0.86
A comparative analysis of methods for predicting clinical outcomes using high-dimensional genomic datasets. J Am Med Inform Assoc (2014) 0.84
Evaluation of a two-stage framework for prediction using big genomic data. Brief Bioinform (2015) 0.80
LEAP: biomarker inference through learning and evaluating association patterns. Genet Epidemiol (2015) 0.80
Sparse expression bases in cancer reveal tumor drivers. Nucleic Acids Res (2015) 0.79
A Bayesian approach for inducing sparsity in generalized linear models with multi-category response. BMC Bioinformatics (2015) 0.79
Mixture SNPs effect on phenotype in genome-wide association studies. BMC Genomics (2015) 0.77
Controlling the Rate of GWAS False Discoveries. Genetics (2016) 0.76
A Variational Bayes Genomic-Enabled Prediction Model with Genotype × Environment Interaction. G3 (Bethesda) (2017) 0.75
A fast algorithm for Bayesian multi-locus model in genome-wide association studies. Mol Genet Genomics (2017) 0.75
A haplotype map of the human genome. Nature (2005) 105.70
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science (2007) 23.38
Personal genomes: The case of the missing heritability. Nature (2008) 19.56
Genome-wide association analysis by lasso penalized logistic regression. Bioinformatics (2009) 12.21
Estimating polygenic effects using markers of the entire genome. Genetics (2003) 8.67
A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes. Am J Hum Genet (2001) 8.47
Mapping complex disease traits with global gene expression. Nat Rev Genet (2009) 7.44
Progress and challenges in genome-wide association studies in humans. Nature (2008) 7.32
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet (2008) 6.66
Two-stage two-locus models in genome-wide association. PLoS Genet (2006) 5.60
Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes. Proc Natl Acad Sci U S A (2005) 5.21
Bayesian LASSO for quantitative trait loci mapping. Genetics (2008) 4.67
Fast and flexible simulation of DNA sequence data. Genome Res (2008) 4.45
Bayesian inference of epistatic interactions in case-control studies. Nat Genet (2007) 4.31
Accommodating linkage disequilibrium in genetic-association analyses via ridge regression. Am J Hum Genet (2008) 3.86
The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol Biol (2007) 3.01
Hierarchical generalized linear models for multiple quantitative trait locus mapping. Genetics (2009) 2.21
Mapping multiple Quantitative Trait Loci by Bayesian classification. Genetics (2004) 1.46
Advances in Bayesian multiple quantitative trait loci mapping in experimental crosses. Heredity (Edinb) (2007) 1.40
Bayesian mapping of quantitative trait loci for multiple complex traits with the use of variance components. Am J Hum Genet (2007) 1.35
Variable selection for large p small n regression models with incomplete data: mapping QTL with epistases. BMC Bioinformatics (2008) 1.18
A variational method for learning sparse and overcomplete representations. Neural Comput (2001) 0.97
Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers. Am J Respir Crit Care Med (2011) 2.12
Lung adenocarcinoma subtypes based on expression of human airway basal cell genes. Eur Respir J (2013) 1.59
Four loci explain 83% of size variation in the horse. PLoS One (2012) 1.40
PCAdmix: principal components-based assignment of ancestry along each chromosome in individuals with admixed ancestry from two or more populations. Hum Biol (2012) 1.37
RNA-Seq quantification of the human small airway epithelium transcriptome. BMC Genomics (2012) 1.28
Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking. Mol Med (2009) 1.24
Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs. Mol Ther (2011) 1.18
Adaptive gene expression divergence inferred from population genomics. PLoS Genet (2007) 1.13
Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations. BMC Genet (2012) 1.01
PUMA: a unified framework for penalized multiple regression analysis of GWAS data. PLoS Comput Biol (2013) 1.00
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Mol Vis (2010) 0.99
Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 0.94
Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar. Hum Mutat (2013) 0.92
Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control. BMC Bioinformatics (2012) 0.91
Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population. PLoS One (2012) 0.89
AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior. Hum Gene Ther (2012) 0.89
Smoking accelerates aging of the small airway epithelium. Respir Res (2014) 0.87
Evolutionary genomics: codon bias and selection on single genomes. Nature (2005) 0.86
Persistent suppression of ocular neovascularization with intravitreal administration of AAVrh.10 coding for bevacizumab. Hum Gene Ther (2011) 0.86
Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer. Cancer Res (2011) 0.85
HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors. Bioinformatics (2013) 0.83
Airway epithelial expression of TLR5 is downregulated in healthy smokers and smokers with chronic obstructive pulmonary disease. J Immunol (2012) 0.82
Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers. BMC Med Genomics (2012) 0.81
IQCB1 and PDE6B mutations cause similar early onset retinal degenerations in two closely related terrier dog breeds. Invest Ophthalmol Vis Sci (2013) 0.81
Development and use of DNA archives at veterinary teaching hospitals to investigate the genetic basis of disease in dogs. J Am Vet Med Assoc (2009) 0.81
Empirical Bayes conditional independence graphs for regulatory network recovery. Bioinformatics (2012) 0.80
Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function. PLoS One (2013) 0.79
Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats. Hum Gene Ther Clin Dev (2013) 0.78
Bayesian linkage analysis of categorical traits for arbitrary pedigree designs. PLoS One (2010) 0.78
Quantitative trait loci for the circadian clock in Neurospora crassa. Genetics (2007) 0.78
Correction: Type 2 Diabetes Risk Allele Loci in the Qatari Population. PLoS One (2016) 0.75
Differential expression of vitamin E and selenium-responsive genes by disease severity in chronic obstructive pulmonary disease. COPD (2013) 0.75
High correlation of the response of upper and lower lobe small airway epithelium to smoking. PLoS One (2013) 0.75
Fast, exact linkage analysis for categorical traits on arbitrary pedigree designs. Genet Epidemiol (2011) 0.75