Published in J Nutr on January 27, 2010
Early developmental conditioning of later health and disease: physiology or pathophysiology? Physiol Rev (2014) 1.86
Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology (2011) 1.85
Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships. Hum Genet (2012) 1.47
Delivery by caesarean section and risk of obesity in preschool age children: a prospective cohort study. Arch Dis Child (2012) 1.35
Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene. J Biol Chem (2011) 1.31
White adipose tissue development in zebrafish is regulated by both developmental time and fish size. Dev Dyn (2010) 1.19
Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons. Endocrinology (2011) 1.01
Effect of citrus flavonoids, naringin and naringenin, on metabolic syndrome and their mechanisms of action. Adv Nutr (2014) 0.99
Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes. Antioxid Redox Signal (2011) 0.97
Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome. Exp Mol Med (2015) 0.93
Healthy conversation skills: increasing competence and confidence in front-line staff. Public Health Nutr (2012) 0.90
Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action. PLoS One (2013) 0.89
A diet based on multiple functional concepts improves cardiometabolic risk parameters in healthy subjects. Nutr Metab (Lond) (2012) 0.87
Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes mellitus or obesity in pregnancy. Exp Diabetes Res (2011) 0.86
Could the improvement of obesity-related co-morbidities depend on modified gut hormones secretion? World J Gastroenterol (2014) 0.85
Do fatty acids affect fetal programming? J Health Popul Nutr (2015) 0.85
Obesity and kidney disease: differential effects of obesity on adipose tissue and kidney inflammation and fibrosis. Curr Opin Nephrol Hypertens (2015) 0.81
Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment. PLoS One (2012) 0.80
Polyphenol Rich Extract of Garcinia pedunculata Fruit Attenuates the Hyperlipidemia Induced by High Fat Diet. Front Pharmacol (2016) 0.79
Early life factors and type 2 diabetes mellitus. J Diabetes Res (2013) 0.79
Fetal programming and early identification of newborns at high risk of free radical-mediated diseases. World J Clin Pediatr (2016) 0.78
High Risk of Metabolic and Adipose Tissue Dysfunctions in Adult Male Progeny, Due to Prenatal and Adulthood Malnutrition Induced by Fructose Rich Diet. Nutrients (2016) 0.78
Water-soluble rice bran enzymatic extract attenuates dyslipidemia, hypertension and insulin resistance in obese Zucker rats. Eur J Nutr (2012) 0.78
Reduced genetic influence on childhood obesity in small for gestational age children. BMC Med Genet (2013) 0.78
Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver. BMC Med Genet (2013) 0.78
A lipid-rich gestational diet predisposes offspring to nonalcoholic fatty liver disease: a potential sequence of events. Hepat Med (2014) 0.77
Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives. Front Pharmacol (2016) 0.77
Micro-RNAs Let7e and 126 in Plasma as Markers of Metabolic Dysfunction in 10 to 12 Years Old Children. PLoS One (2015) 0.77
Moderately increased maternal dietary energy intake delays foetal skeletal muscle differentiation and maturity in pigs. Eur J Nutr (2015) 0.77
Mechanisms underlying the beneficial effect of soy protein in improving the metabolic abnormalities in the liver and skeletal muscle of dyslipemic insulin resistant rats. Eur J Nutr (2014) 0.76
The role of insulin resistance in diabetic neuropathy in Koreans with type 2 diabetes mellitus: a 6-year follow-up study. Yonsei Med J (2014) 0.76
Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. Lipids Health Dis (2015) 0.76
Extrauterine growth restriction on pulmonary vascular endothelial dysfunction in adult male rats: the role of epigenetic mechanisms. J Hypertens (2014) 0.76
Moderately decreased maternal dietary energy intake during pregnancy reduces fetal skeletal muscle mitochondrial biogenesis in the pigs. Genes Nutr (2016) 0.75
The Association between Impaired Glucose Regulation and Prognosis of Chinese Patients with Intracerebral Hemorrhage. Sci Rep (2016) 0.75
Knowledge and attitudes towards obesity among primary school children in Dar es Salaam, Tanzania. Niger Med J (2015) 0.75
Maternal Fructose Exposure Programs Metabolic Syndrome-Associated Bladder Overactivity in Young Adult Offspring. Sci Rep (2016) 0.75
385 C/A polymorphism of the fatty acid amide hydrolase gene is associated with metabolic syndrome in the Chinese Han population. Arch Med Sci (2011) 0.75
Longitudinal associations of lifestyle factors and weight status with insulin resistance (HOMA-IR) in preadolescent children: the large prospective cohort study IDEFICS. Int J Behav Nutr Phys Act (2016) 0.75
The Gut Microbiota as a Therapeutic Target in IBD and Metabolic Disease: A Role for the Bile Acid Receptors FXR and TGR5. Microorganisms (2015) 0.75
Getting big on BPA: role for BPA in obesity? Endocrinology (2011) 0.75
Maternal consumption of fish oil programs reduced adiposity in broiler chicks. Sci Rep (2017) 0.75
Dietary arginine affects the insulin signaling pathway, glucose metabolism and lipogenesis in juvenile blunt snout bream Megalobrama amblycephala. Sci Rep (2017) 0.75
Programming of Essential Hypertension: What Pediatric Cardiologists Need to Know. Pediatr Cardiol (2015) 0.75
Effect of in utero and early-life conditions on adult health and disease. N Engl J Med (2008) 14.46
Living with the past: evolution, development, and patterns of disease. Science (2004) 7.14
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr (2005) 4.57
Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol (2009) 3.25
Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes (2011) 3.18
Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology (2009) 3.11
Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol (2006) 3.02
Predictive adaptive responses and human evolution. Trends Ecol Evol (2005) 2.90
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr (2008) 2.55
The developmental origins of the metabolic syndrome. Trends Endocrinol Metab (2004) 2.55
Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br J Nutr (2007) 2.48
Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatr Res (2007) 2.47
Environmental influences during development and their later consequences for health and disease: implications for the interpretation of empirical studies. Proc Biol Sci (2005) 2.40
Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet (2009) 2.35
Metabolic plasticity during mammalian development is directionally dependent on early nutritional status. Proc Natl Acad Sci U S A (2007) 2.26
Developmental origins of disease paradigm: a mechanistic and evolutionary perspective. Pediatr Res (2004) 2.11
Non-genomic transgenerational inheritance of disease risk. Bioessays (2007) 2.07
The developmental origins of adult disease. Matern Child Nutr (2005) 2.05
Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension (2003) 2.00
Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life? Br J Nutr (2007) 1.85
Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol Metab (2010) 1.78
Evolution, development and timing of puberty. Trends Endocrinol Metab (2005) 1.75
Mechanisms of disease: in utero programming in the pathogenesis of hypertension. Nat Clin Pract Nephrol (2006) 1.71
Maternal constraint of fetal growth and its consequences. Semin Fetal Neonatal Med (2004) 1.70
Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J Nutr (2009) 1.61
The role of developmental plasticity and epigenetics in human health. Birth Defects Res C Embryo Today (2011) 1.55
Low birthweight and subsequent obesity in Japan. Lancet (2007) 1.54
Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy. Am J Physiol Regul Integr Comp Physiol (2004) 1.53
The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum Dev (2004) 1.45
Cardiovascular and endocrine responses to cutaneous electrical stimulation after fentanyl in the ovine fetus. Am J Obstet Gynecol (2004) 1.40
Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood. Proc Natl Acad Sci U S A (2007) 1.36
Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice. Br J Nutr (2009) 1.29
Maternal protein restriction in the rat impairs resistance artery but not conduit artery function in pregnant offspring. J Physiol (2002) 1.27
Life-long echoes--a critical analysis of the developmental origins of adult disease model. Biol Neonate (2004) 1.26
Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease. Biol Reprod (2007) 1.25
Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease. J Physiol (2008) 1.23
Folate supplementation during pregnancy improves offspring cardiovascular dysfunction induced by protein restriction. Hypertension (2006) 1.20
Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition. PLoS One (2011) 1.18
Early-life prevention of non-communicable diseases. Lancet (2013) 1.14
Developmental origins of health and disease: reducing the burden of chronic disease in the next generation. Genome Med (2010) 1.13
Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring. J Physiol (2008) 1.12
Prenatal programming of postnatal endocrine responses by glucocorticoids. Reproduction (2002) 1.11
Maternal protein restriction with or without folic acid supplementation during pregnancy alters the hepatic transcriptome in adult male rats. Br J Nutr (2010) 1.10
The long-term effects of prenatal development on growth and metabolism. Semin Reprod Med (2011) 1.10
Fetal and neonatal pathways to obesity. Front Horm Res (2008) 1.08
Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function. J Physiol (2008) 1.08
An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth. Clin Endocrinol (Oxf) (2012) 1.04
Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem (2012) 1.03
Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases. Epigenomics (2011) 1.01
High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep. Am J Physiol Regul Integr Comp Physiol (2007) 1.01
Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis. PLoS One (2012) 1.00
Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development. J Physiol (2008) 1.00
Human growth: evolutionary and life history perspectives. Nestle Nutr Inst Workshop Ser (2013) 0.99
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice. PLoS One (2012) 0.99
Dietary protein restriction during F0 pregnancy in rats induces transgenerational changes in the hepatic transcriptome in female offspring. PLoS One (2011) 0.98
Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro. J Physiol (2007) 0.98
Does estrogen affect the development of abnormal vascular function in offspring of rats fed a low-protein diet in pregnancy? Pediatr Res (2006) 0.98
Predictive adaptive responses in perspective. Trends Endocrinol Metab (2008) 0.96
Atorvastatin restores endothelial function in offspring of protein-restricted rats in a cholesterol-independent manner. Hypertension (2009) 0.96
Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring. Hypertension (2008) 0.95
Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep. J Physiol (2003) 0.93
Prenatal factors contribute to the emergence of kwashiorkor or marasmus in severe undernutrition: evidence for the predictive adaptation model. PLoS One (2012) 0.92
Transmission of raised blood pressure and endothelial dysfunction to the F2 generation induced by maternal protein restriction in the F0, in the absence of dietary challenge in the F1 generation. Br J Nutr (2008) 0.91
Sex- and age-specific effects of nutrition in early gestation and early postnatal life on hypothalamo-pituitary-adrenal axis and sympathoadrenal function in adult sheep. J Physiol (2010) 0.91
Associations between DNA methylation of a glucocorticoid receptor promoter and acute stress responses in a large healthy adult population are largely explained by lifestyle and educational differences. Psychoneuroendocrinology (2011) 0.91
Developmental origins of the metabolic syndrome: body clocks and stress responses. Brain Behav Immun (2010) 0.91
Maternal undernutrition leads to endothelial dysfunction in adult male rat offspring independent of postnatal diet. Br J Nutr (2008) 0.91
Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development. PLoS One (2012) 0.90
A 200-year perspective on alternative stable state theory and lake management from a biomanipulated shallow lake. Ecol Appl (2012) 0.90
Fetal size in the second trimester is associated with the duration of pregnancy, small fetuses having longer pregnancies. BMC Pregnancy Childbirth (2008) 0.89
Vasodilation to vascular endothelial growth factor in the uterine artery of the pregnant rat is blunted by low dietary protein intake. Pediatr Res (2002) 0.89
Increasing the folic acid content of maternal or post-weaning diets induces differential changes in phosphoenolpyruvate carboxykinase mRNA expression and promoter methylation in rats. Br J Nutr (2011) 0.88
Effects of chronic hypoxia and protein malnutrition on growth in the developing chick. Am J Obstet Gynecol (2002) 0.87
Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth. J Bone Miner Res (2014) 0.86
The effect of maternal undernutrition in early gestation on gestation length and fetal and postnatal growth in sheep. Pediatr Res (2007) 0.86
Maternal low-protein diet during mouse pre-implantation development induces vascular dysfunction and altered renin-angiotensin-system homeostasis in the offspring. Br J Nutr (2010) 0.86
Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. Br J Nutr (2003) 0.86
Aquatic persistence of eight pharmaceuticals in a microcosm study. Environ Toxicol Chem (2004) 0.85
The fetal llama versus the fetal sheep: different strategies to withstand hypoxia. High Alt Med Biol (2003) 0.85
Hepatic artery hemodynamics suggest operation of a buffer response in the human fetus. Reprod Sci (2008) 0.84
Nutritional challenges during development induce sex-specific changes in glucose homeostasis in the adult sheep. Am J Physiol Endocrinol Metab (2006) 0.84
Effects of pre-natal and early post-natal undernutrition on adult internal thoracic artery function. Eur J Cardiothorac Surg (2005) 0.83
Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply. J Clin Endocrinol Metab (2004) 0.83
Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in the llama fetus. J Physiol (2002) 0.82
The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. Biochim Biophys Acta (2004) 0.82
Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium from intrauterine growth restricted fetuses. Epigenetics (2013) 0.82
Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent. Exp Physiol (2009) 0.82
Umbilical venous-arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools. Br J Nutr (2011) 0.81
Appetite regulatory mechanisms and food intake in mice are sensitive to mismatch in diets between pregnancy and postnatal periods. Brain Res (2008) 0.81
The effect of systemic administration of lipopolysaccharide on cerebral haemodynamics and oxygenation in the 0.65 gestation ovine fetus in utero. BJOG (2003) 0.81
Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano. Cardiovasc Res (2007) 0.80
Glucose metabolism in adult survivors of severe acute malnutrition. J Clin Endocrinol Metab (2014) 0.80
Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring. Eur J Nutr (2014) 0.80
Expression of agouti-related peptide, neuropeptide Y, pro-opiomelanocortin and the leptin receptor isoforms in fetal mouse brain from pregnant dams on a protein-restricted diet. Brain Res Mol Brain Res (2005) 0.80
Non-imprinted epigenetics in fetal and postnatal development and growth. Nestle Nutr Inst Workshop Ser (2013) 0.79
The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep. J Physiol (2008) 0.79
Macrophytes in shallow lakes: relationships with water, sediment and watershed characteristics. (2013) 0.79
Sensitivity of housekeeping genes in the hypothalamus to mismatch in diets between pre- and postnatal periods in mice. Neurosci Lett (2008) 0.78