Published in J Physiol on December 22, 2008
Early developmental conditioning of later health and disease: physiology or pathophysiology? Physiol Rev (2014) 1.86
The fetal brain sparing response to hypoxia: physiological mechanisms. J Physiol (2016) 1.01
Trade-offs in relative limb length among Peruvian children: extending the thrifty phenotype hypothesis to limb proportions. PLoS One (2012) 0.87
Adenosine A₂a receptors and O₂ sensing in development. Am J Physiol Regul Integr Comp Physiol (2011) 0.81
Associations between arterial oxygen saturation, body size and limb measurements among high-altitude Andean children. Am J Hum Biol (2013) 0.79
Pre- and early-postnatal nutrition modify gene and protein expressions of muscle energy metabolism markers and phospholipid Fatty Acid composition in a muscle type specific manner in sheep. PLoS One (2013) 0.79
Differential pathways to adult metabolic dysfunction following poor nutrition at two critical developmental periods in sheep. PLoS One (2014) 0.75
Analysis of serial measurements in medical research. BMJ (1990) 16.69
Living with the past: evolution, development, and patterns of disease. Science (2004) 7.14
Early growth and coronary heart disease in later life: longitudinal study. BMJ (2001) 5.25
Blood flow measurements with radionuclide-labeled particles. Prog Cardiovasc Dis (1977) 4.57
The relation of small head circumference and thinness at birth to death from cardiovascular disease in adult life. BMJ (1993) 4.26
Mother's weight in pregnancy and coronary heart disease in a cohort of Finnish men: follow up study. BMJ (1997) 3.63
Foetal respiratory movements, electrocortical and cardiovascular responses to hypoxaemia and hypercapnia in sheep. J Physiol (1974) 2.88
Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development (2000) 2.82
Prenatal exposure to the Dutch famine and disease in later life: an overview. Reprod Toxicol (2005) 2.52
Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45. Heart (2000) 2.35
Cardiovascular responses to hypoxemia and acidemia in fetal lambs. Am J Obstet Gynecol (1974) 2.18
Afferent and efferent components of the cardiovascular reflex responses to acute hypoxia in term fetal sheep. J Physiol (1993) 2.16
Low glucose-sensing cells in the carotid body. Nat Neurosci (2002) 1.76
Evidence that carotid bodies play an important role in glucoregulation in vivo. Diabetes (2000) 1.72
Blood flow to fetal organs as a function of arterial oxygen content. Am J Obstet Gynecol (1979) 1.52
Plasma catecholamines in foetal and adult sheep. J Physiol (1975) 1.43
Fetal liver-sparing cardiovascular adaptations linked to mother's slimness and diet. Circ Res (2004) 1.43
Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood. Proc Natl Acad Sci U S A (2007) 1.36
Neurotransmission and neuromodulation in the chemosensory carotid body. Auton Neurosci (2005) 1.26
Peri-implantation undernutrition programs blunted angiotensin II evoked baroreflex responses in young adult sheep. Hypertension (2004) 1.23
Glucose responding neurons in the nucleus tractus solitarius of the rat: in vitro study. Brain Res (1984) 1.15
Maternal undernutrition increases arterial blood pressure in the sheep fetus during late gestation. J Physiol (2001) 1.14
Periconceptional undernutrition alters growth trajectory and metabolic and endocrine responses to fasting in late-gestation fetal sheep. Pediatr Res (2005) 1.10
Carotid sinus receptors participate in glucose homeostasis. Respir Physiol (1988) 1.10
Effects of prevailing hypoxaemia, acidaemia or hypoglycaemia upon the cardiovascular, endocrine and metabolic responses to acute hypoxaemia in the ovine fetus. J Physiol (2002) 1.06
Effect of maternal undernutrition in early gestation on ovine fetal blood pressure and cardiovascular reflexes. Am J Physiol Regul Integr Comp Physiol (2000) 1.02
Chemoreflex and endocrine components of cardiovascular responses to acute hypoxemia in the llama fetus. Am J Physiol (1996) 0.99
The origin of cortisol in the blood of fetal sheep. J Endocrinol (1982) 0.95
Cardiovascular and hypothalamic-pituitary-adrenal axis development in late gestation fetal sheep and young lambs following modest maternal nutrient restriction in early gestation. Reprod Fertil Dev (2000) 0.94
Influence of restricted maternal nutrition in early to mid gestation on placental and fetal development at term in sheep. Pediatr Res (1998) 0.94
Effects of cord compression on fetal blood flow distribution and O2 delivery. Am J Physiol (1987) 0.89
Use of an automated fluorescent microsphere method to measure regional blood flow in the fetal lamb. Can J Physiol Pharmacol (1997) 0.88
Responses of the fetal pituitary-adrenal axis to acute and chronic hypoglycemia during late gestation in the sheep. Endocrinology (2001) 0.87
Simultaneous measurements of umbilical venous, fetal hepatic, and ductus venosus blood flow in growth-restricted human fetuses. Am J Obstet Gynecol (2004) 0.86
Neural control of blood glucose homeostasis; effect of microinjection of glucose into hypothalamic nuclei on efferent activity of pancreatic branch of vagus nerve in the rat. Brain Res Bull (1988) 0.85
Blood flow and oxygen delivery to fetal organs and tissues during sustained hypoxemia. Am J Physiol (1990) 0.85
Distribution and recirculation of umbilical and systemic venous blood flow in fetal lambs during hypoxia. J Dev Physiol (1981) 0.84
Angiotensin II and cardiovascular chemoreflex responses to acute hypoxia in late gestation fetal sheep. J Physiol (1998) 0.84
Regional blood flow and the endocrine response to sustained hypoxemia in the preterm ovine fetus. Pediatr Res (1996) 0.83
Blood flow through the ductus venosus in singleton and multifetal pregnancies and in fetuses with intrauterine growth retardation. Am J Obstet Gynecol (1998) 0.83
Sympathoadrenal responses during hypoglycemia, hyperinsulinemia, and hypoxemia in the ovine fetus. Am J Physiol (1991) 0.83
Elevation in plasma catecholamines in response to insulin stress is under both neuronal and nonneuronal control. Endocrinology (1986) 0.83
The carotid bodies influence growth responses to moderate maternal undernutrition in late-gestation fetal sheep. BJOG (2008) 0.82
Comparison of regional blood flow values measured by radioactive and fluorescent microspheres. Eur Surg Res (2002) 0.81
Changes in blood glucose concentration in the carotid body-sinus modify brain glucose retention. Brain Res (1994) 0.81
Fetal catecholamine responses to maternal hypoglycemia. Am J Physiol (1990) 0.79
A method for assessment of blood volume parameters in pregnant sheep using fluorescein-labelled dextran. Placenta (2007) 0.78
Fetal bradycardia resulting from maternal hypoglycemia. A report of two cases. J Reprod Med (1995) 0.78
The effect of elevation of maternal plasma catecholamines on the fetus and placenta of the pregnant sheep. J Dev Physiol (1986) 0.77
Effects of hypoglycaemia on fetal heart activity and umbilical artery Doppler velocity waveforms in pregnant women with insulin-dependent diabetes mellitus. Br J Obstet Gynaecol (1996) 0.77
The kidney is resistant to chronic hypoglycaemia in late-gestation fetal sheep. Can J Physiol Pharmacol (2007) 0.76
Effect of probenecid on breathing movements and cerebral clearance of prostaglandin E2 in fetal sheep. J Physiol (1998) 0.76
Nitric oxide modulates spontaneous swallowing behavior in near-term ovine fetus. Am J Physiol (1999) 0.76
Effect of insulin on the distribution of cardiac output in the fetal lamb. Pediatr Res (1987) 0.76
Circulatory and metabolic effects of alpha-adrenergic blockade in the hyperinsulinemic ovine fetus. J Soc Gynecol Investig (1996) 0.76
Effect of in utero and early-life conditions on adult health and disease. N Engl J Med (2008) 14.46
Living with the past: evolution, development, and patterns of disease. Science (2004) 7.14
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr (2005) 4.57
Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol (2009) 3.25
Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes (2011) 3.18
Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology (2009) 3.11
Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol (2006) 3.02
Predictive adaptive responses and human evolution. Trends Ecol Evol (2005) 2.90
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr (2008) 2.55
The developmental origins of the metabolic syndrome. Trends Endocrinol Metab (2004) 2.55
Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br J Nutr (2007) 2.48
Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatr Res (2007) 2.47
Environmental influences during development and their later consequences for health and disease: implications for the interpretation of empirical studies. Proc Biol Sci (2005) 2.40
Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet (2009) 2.35
Metabolic plasticity during mammalian development is directionally dependent on early nutritional status. Proc Natl Acad Sci U S A (2007) 2.26
Developmental origins of disease paradigm: a mechanistic and evolutionary perspective. Pediatr Res (2004) 2.11
Non-genomic transgenerational inheritance of disease risk. Bioessays (2007) 2.07
The developmental origins of adult disease. Matern Child Nutr (2005) 2.05
Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension (2003) 2.00
Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life? Br J Nutr (2007) 1.85
Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol Metab (2010) 1.78
Evolution, development and timing of puberty. Trends Endocrinol Metab (2005) 1.75
Mechanisms of disease: in utero programming in the pathogenesis of hypertension. Nat Clin Pract Nephrol (2006) 1.71
Maternal constraint of fetal growth and its consequences. Semin Fetal Neonatal Med (2004) 1.70
Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J Nutr (2009) 1.61
The role of developmental plasticity and epigenetics in human health. Birth Defects Res C Embryo Today (2011) 1.55
Low birthweight and subsequent obesity in Japan. Lancet (2007) 1.54
Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy. Am J Physiol Regul Integr Comp Physiol (2004) 1.53
The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum Dev (2004) 1.45
The developmental origins, mechanisms, and implications of metabolic syndrome. J Nutr (2010) 1.41
Cardiovascular and endocrine responses to cutaneous electrical stimulation after fentanyl in the ovine fetus. Am J Obstet Gynecol (2004) 1.40
Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood. Proc Natl Acad Sci U S A (2007) 1.36
Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice. Br J Nutr (2009) 1.29
Maternal protein restriction in the rat impairs resistance artery but not conduit artery function in pregnant offspring. J Physiol (2002) 1.27
Clinical evaluation of postpartum vaginal mucus reflects uterine bacterial infection and the immune response in cattle. Theriogenology (2005) 1.27
Life-long echoes--a critical analysis of the developmental origins of adult disease model. Biol Neonate (2004) 1.26
Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease. Biol Reprod (2007) 1.25
Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease. J Physiol (2008) 1.23
Folate supplementation during pregnancy improves offspring cardiovascular dysfunction induced by protein restriction. Hypertension (2006) 1.20
Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition. PLoS One (2011) 1.18
Early-life prevention of non-communicable diseases. Lancet (2013) 1.14
Developmental origins of health and disease: reducing the burden of chronic disease in the next generation. Genome Med (2010) 1.13
Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring. J Physiol (2008) 1.12
Prenatal programming of postnatal endocrine responses by glucocorticoids. Reproduction (2002) 1.11
The long-term effects of prenatal development on growth and metabolism. Semin Reprod Med (2011) 1.10
Maternal protein restriction with or without folic acid supplementation during pregnancy alters the hepatic transcriptome in adult male rats. Br J Nutr (2010) 1.10
Fetal and neonatal pathways to obesity. Front Horm Res (2008) 1.08
Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function. J Physiol (2008) 1.08
An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth. Clin Endocrinol (Oxf) (2012) 1.04
Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem (2012) 1.03
High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep. Am J Physiol Regul Integr Comp Physiol (2007) 1.01
Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases. Epigenomics (2011) 1.01
Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development. J Physiol (2008) 1.00
Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis. PLoS One (2012) 1.00
Human growth: evolutionary and life history perspectives. Nestle Nutr Inst Workshop Ser (2013) 0.99
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice. PLoS One (2012) 0.99
Dietary protein restriction during F0 pregnancy in rats induces transgenerational changes in the hepatic transcriptome in female offspring. PLoS One (2011) 0.98
Does estrogen affect the development of abnormal vascular function in offspring of rats fed a low-protein diet in pregnancy? Pediatr Res (2006) 0.98
Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro. J Physiol (2007) 0.98
Atorvastatin restores endothelial function in offspring of protein-restricted rats in a cholesterol-independent manner. Hypertension (2009) 0.96
Predictive adaptive responses in perspective. Trends Endocrinol Metab (2008) 0.96
Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring. Hypertension (2008) 0.95
Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep. J Physiol (2003) 0.93
Prenatal factors contribute to the emergence of kwashiorkor or marasmus in severe undernutrition: evidence for the predictive adaptation model. PLoS One (2012) 0.92
Transmission of raised blood pressure and endothelial dysfunction to the F2 generation induced by maternal protein restriction in the F0, in the absence of dietary challenge in the F1 generation. Br J Nutr (2008) 0.91
Associations between DNA methylation of a glucocorticoid receptor promoter and acute stress responses in a large healthy adult population are largely explained by lifestyle and educational differences. Psychoneuroendocrinology (2011) 0.91
Maternal undernutrition leads to endothelial dysfunction in adult male rat offspring independent of postnatal diet. Br J Nutr (2008) 0.91
Sex- and age-specific effects of nutrition in early gestation and early postnatal life on hypothalamo-pituitary-adrenal axis and sympathoadrenal function in adult sheep. J Physiol (2010) 0.91
Developmental origins of the metabolic syndrome: body clocks and stress responses. Brain Behav Immun (2010) 0.91
Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development. PLoS One (2012) 0.90
A 200-year perspective on alternative stable state theory and lake management from a biomanipulated shallow lake. Ecol Appl (2012) 0.90
Vasodilation to vascular endothelial growth factor in the uterine artery of the pregnant rat is blunted by low dietary protein intake. Pediatr Res (2002) 0.89
Fetal size in the second trimester is associated with the duration of pregnancy, small fetuses having longer pregnancies. BMC Pregnancy Childbirth (2008) 0.89
Increasing the folic acid content of maternal or post-weaning diets induces differential changes in phosphoenolpyruvate carboxykinase mRNA expression and promoter methylation in rats. Br J Nutr (2011) 0.88
Effects of chronic hypoxia and protein malnutrition on growth in the developing chick. Am J Obstet Gynecol (2002) 0.87
Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth. J Bone Miner Res (2014) 0.86
The effect of maternal undernutrition in early gestation on gestation length and fetal and postnatal growth in sheep. Pediatr Res (2007) 0.86
Maternal low-protein diet during mouse pre-implantation development induces vascular dysfunction and altered renin-angiotensin-system homeostasis in the offspring. Br J Nutr (2010) 0.86
Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. Br J Nutr (2003) 0.86
Aquatic persistence of eight pharmaceuticals in a microcosm study. Environ Toxicol Chem (2004) 0.85
The fetal llama versus the fetal sheep: different strategies to withstand hypoxia. High Alt Med Biol (2003) 0.85
Possibilities for fertility restoration: a new surgical technique. Int Surg (2006) 0.84
Nutritional challenges during development induce sex-specific changes in glucose homeostasis in the adult sheep. Am J Physiol Endocrinol Metab (2006) 0.84
Hepatic artery hemodynamics suggest operation of a buffer response in the human fetus. Reprod Sci (2008) 0.84