Impaired expression of genes regulating cholesterol efflux in human osteoarthritic chondrocytes.

PubWeight™: 1.03‹?› | Rank: Top 15%

🔗 View Article (PMID 20108316)

Published in J Orthop Res on August 01, 2010

Authors

Aspasia Tsezou1, Dimitrios Iliopoulos, Konstantinos N Malizos, Theodora Simopoulou

Author Affiliations

1: Department of Biology, Medical School, University of Thessaly, Mezourlo Hill, 41222 Larissa, Greece. atsezou@med.uth.gr

Articles citing this

Metabolic syndrome meets osteoarthritis. Nat Rev Rheumatol (2012) 1.75

The relationship between hand osteoarthritis and serum leptin concentration in participants of the Third National Health and Nutrition Examination Survey. Arthritis Res Ther (2012) 0.96

Lipid transport and metabolism in healthy and osteoarthritic cartilage. Int J Mol Sci (2013) 0.89

Central role of SREBP-2 in the pathogenesis of osteoarthritis. PLoS One (2012) 0.89

Role of liver X receptors in cholesterol efflux and inflammatory signaling (review). Mol Med Rep (2012) 0.88

Nuclear receptors in bone physiology and diseases. Physiol Rev (2013) 0.86

The mechanism of apoliprotein A1 down-regulated by Hepatitis B virus. Lipids Health Dis (2016) 0.82

MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes. Arthritis Res Ther (2015) 0.81

Apolipoprotein-A1 as a damage-associated molecular patterns protein in osteoarthritis: ex vivo and in vitro pro-inflammatory properties. PLoS One (2015) 0.80

The Role of MicroRNAs and Their Targets in Osteoarthritis. Curr Rheumatol Rep (2016) 0.79

Liver X receptor gene polymorphisms in tuberculosis: effect on susceptibility. PLoS One (2014) 0.78

Novel effects of sarcopenic osteoarthritis on metabolic syndrome, insulin resistance, osteoporosis, and bone fracture: the national survey. Osteoporos Int (2016) 0.78

The Role of miRNAs in Common Inflammatory Arthropathies: Osteoarthritis and Gouty Arthritis. Biomolecules (2016) 0.77

Identification of potential prognostic markers for knee osteoarthritis by serum proteomic analysis. Biomark Insights (2013) 0.77

Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage. Sci Rep (2015) 0.75

Effects of sesame seed supplementation on lipid profile and oxidative stress biomarkers in patients with knee osteoarthritis. Health Promot Perspect (2014) 0.75

Bone and high-density lipoprotein: The beginning of a beautiful friendship. World J Orthop (2016) 0.75

Metabolic Syndrome Increases the Risk for Knee Osteoarthritis: A Meta-Analysis. Evid Based Complement Alternat Med (2016) 0.75

Nuclear receptors regulate lipid metabolism and oxidative stress markers in chondrocytes. J Mol Med (Berl) (2017) 0.75

Articles by these authors

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell (2008) 7.56

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res (2009) 6.74

An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell (2011) 4.29

A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases. Cancer Cell (2010) 4.02

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity (2009) 3.58

Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell (2013) 3.08

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell (2011) 2.99

Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One (2008) 2.65

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proc Natl Acad Sci U S A (2012) 2.11

Diagnostic accuracy of a new clinical test (the Thessaly test) for early detection of meniscal tears. J Bone Joint Surg Am (2005) 1.96

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Hum Mol Genet (2008) 1.91

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes. Proc Natl Acad Sci U S A (2010) 1.90

Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell (2010) 1.86

Concern WWOX gene restoration prevents lung cancer growth in vitro and in vivo. Proc Natl Acad Sci U S A (2005) 1.84

Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. Cancer Res (2006) 1.71

Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut (2012) 1.65

Three-dimensional finite element modeling of guided ultrasound wave propagation in intact and healing long bones. J Acoust Soc Am (2007) 1.50

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression. Ann Rheum Dis (2011) 1.49

The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma. Cancer (2004) 1.49

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Res (2011) 1.48

A role for the WWOX gene in prostate cancer. Cancer Res (2006) 1.45

Triple nerve block at the knee for foot and ankle surgery performed by the surgeon: difficulties and efficiency. Foot Ankle Int (2009) 1.42

MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis. Gastroenterology (2013) 1.41

Tourniquet use does not affect rehabilitation, return to activities, and muscle damage after arthroscopic meniscectomy: a prospective randomized clinical study. Arthroscopy (2012) 1.40

Epigenetic aberrations during oncogenesis. Cell Mol Life Sci (2011) 1.32

New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. PLoS One (2010) 1.27

Factors affecting the quality of life after total knee arthroplasties: a prospective study. BMC Musculoskelet Disord (2012) 1.27

MicroRNA Gene Networks in Oncogenesis. Curr Genomics (2009) 1.26

Diagnosis of periprosthetic joint infection. J Arthroplasty (2013) 1.24

Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors. Gastroenterology (2011) 1.24

Wwox and Ap2gamma expression levels predict tamoxifen response. Clin Cancer Res (2007) 1.22

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci U S A (2012) 1.22

Genetic background of osteonecrosis: associated with thrombophilic mutations? Clin Orthop Relat Res (2004) 1.20

A mid-term clinical outcome study of the Advance Medial Pivot knee arthroplasty. Knee (2009) 1.20

Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. Int J Cancer (2007) 1.15

MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis. Clin Endocrinol (Oxf) (2009) 1.15

Concordant loss of fragile gene expression early in breast cancer development. Pathol Int (2005) 1.15

Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations. Hum Mol Genet (2009) 1.15

A comparison of early versus delayed repair of traumatic rotator cuff tears. Knee Surg Sports Traumatol Arthrosc (2011) 1.14

Lipid metabolism and osteoarthritis: lessons from atherosclerosis. Prog Lipid Res (2010) 1.12

Protective effect of atorvastatin in cultured osteoarthritic chondrocytes. J Orthop Res (2010) 1.12

Diagnosis of periprosthetic joint infection. J Orthop Res (2014) 1.08

Differences in graft orientation using the transtibial and anteromedial portal technique in anterior cruciate ligament reconstruction: a magnetic resonance imaging study. Knee Surg Sports Traumatol Arthrosc (2009) 1.08

Outcome after tantalum rod implantation for treatment of femoral head osteonecrosis: 26 hips followed for an average of 3 years. Acta Orthop (2009) 1.08

Autograft contamination during preparation for anterior cruciate ligament reconstruction. J Bone Joint Surg Am (2008) 1.06

Guided ultrasound wave propagation in intact and healing long bones. Ultrasound Med Biol (2006) 1.04

The 677C-->T mutation of the methylene-tetrahydrofolate reductase gene in the pathogenesis of osteonecrosis of the femoral head. Haematologica (2002) 1.03

MR imaging findings in early osteoarthritis of the knee. Eur J Radiol (2004) 1.03

Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes. Arthritis Res Ther (2012) 1.02

An ultrasound wearable system for the monitoring and acceleration of fracture healing in long bones. IEEE Trans Biomed Eng (2005) 1.02

Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor. J Biol Chem (2006) 1.02

Daptomycin use in patients with osteomyelitis: a preliminary report from the EU-CORE(SM) database. J Antimicrob Chemother (2013) 1.02

Vascularized periosteal flaps of distal forearm and hand. J Trauma (2005) 1.01

Vascularized fibula transfer for lower limb reconstruction. Microsurgery (2011) 0.99

miRNAs link metabolic reprogramming to oncogenesis. Trends Endocrinol Metab (2013) 0.99

Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling. Mol Cancer Res (2007) 0.95

The role of MR imaging in staging femoral head osteonecrosis. Eur J Radiol (2007) 0.95

The socioeconomic impact of musculoskeletal infections. J Bone Joint Surg Am (2010) 0.94

Cumulative keyboard strokes: a possible risk factor for carpal tunnel syndrome. J Occup Med Toxicol (2012) 0.94

A capsular-based vascularized distal radius graft for proximal pole scaphoid pseudarthrosis. J Hand Surg Am (2006) 0.94

Arthroscopic repair for chronic anterior shoulder instability: a comparative study between patients with Bankart lesions and patients with combined Bankart and superior labral anterior posterior lesions. Am J Sports Med (2009) 0.93

Arthroscopic meniscal repair: a comparative study between three different surgical techniques. Knee Surg Sports Traumatol Arthrosc (2006) 0.93

Meniscal and articular cartilage lesions in the anterior cruciate ligament-deficient knee: correlation between time from injury and knee scores. Knee Surg Sports Traumatol Arthrosc (2013) 0.93

Clinical and epidemiological features of upper-extremity infections caused by Staphylococcus aureus carrying the PVL gene: a four-year study in Greece. Med Sci Monit (2008) 0.93

Radial nerve palsy associated with humeral shaft fracture. Is the energy of trauma a prognostic factor? Injury (2011) 0.93

The growth differentiation factor 5 (GDF5) core promoter polymorphism is not associated with knee osteoarthritis in the Greek population. J Orthop Res (2008) 0.92

Novel model for studying hematogenous infection in an experimental setting of implant-related infection by a community-acquired methicillin-resistant S. aureus strain. J Orthop Res (2008) 0.92

Low-intensity transosseous ultrasound accelerates osteotomy healing in a sheep fracture model. J Bone Joint Surg Am (2004) 0.92

Femoral head osteonecrosis: volumetric MRI assessment and outcome. Eur J Radiol (2007) 0.91

Distal ulnar implant arthroplasty as a definitive treatment of a recurrent giant-cell tumor. J Hand Surg Am (2007) 0.91

Combined anterior and posterior shoulder dislocation as a manifestation of a brain tumour. Acta Orthop Belg (2004) 0.91

Low-density lipoprotein receptor-related protein 5 (LRP5) expression in human osteoarthritic chondrocytes. J Orthop Res (2010) 0.91

Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility. J Hum Genet (2007) 0.90

Survivin regulation by HER2 through NF-κB and c-myc in irradiated breast cancer cells. J Cell Mol Med (2011) 0.90

Central role of SREBP-2 in the pathogenesis of osteoarthritis. PLoS One (2012) 0.89

Repair of an anteroinferior glenoid defect by the latarjet procedure: quantitative assessment of the repair by computed tomography. Arthroscopy (2010) 0.89

Genetic variation including nonsynonymous polymorphisms of a major aggrecanase, ADAMTS-5, in susceptibility to osteoarthritis. Arthritis Rheum (2008) 0.88

Reduced expression of ribosomal proteins relieves microRNA-mediated repression. Mol Cell (2012) 0.88

MicroRNA-gene signaling pathways in pancreatic cancer. Biomed J (2013) 0.87

Differential effect of Pistacia vera extracts on experimental atherosclerosis in the rabbit animal model: an experimental study. Lipids Health Dis (2010) 0.87

Does electric stimulation of the vastus medialis muscle influence rehabilitation after total knee replacement? Orthopedics (2011) 0.86

Interplay between αvβ3 integrin and nucleolin regulates human endothelial and glioma cell migration. J Biol Chem (2012) 0.86

Bone morphogenetic proteins (BMPs) expression in the femoral heads of patients with avascular necrosis. Mol Biol Rep (2013) 0.86

Ultrasonic monitoring of bone fracture healing. IEEE Trans Ultrason Ferroelectr Freq Control (2008) 0.86

Factor V Leiden and prothrombin gene mutations in femoral head osteonecrosis. Thromb Haemost (2002) 0.86

CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors. Oncogene (2004) 0.85

Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus. PLoS One (2010) 0.85

Evaluation of the bone bridge between the bone tunnels after anatomic double-bundle anterior cruciate ligament reconstruction: a multidetector computed tomography study. Am J Sports Med (2010) 0.85

Evaluation of meniscal repair with serial magnetic resonance imaging: a comparative study between conventional MRI and indirect MR arthrography. Eur J Radiol (2004) 0.84

Systems biology in inflammatory bowel diseases: ready for prime time. Curr Opin Gastroenterol (2014) 0.84

Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes. J Cell Mol Med (2009) 0.84

The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells. Int J Oncol (2009) 0.84

The catabolic role of toll-like receptor 2 (TLR-2) mediated by the NF-κB pathway in septic arthritis. J Orthop Res (2010) 0.84

Association of KLOTHO gene polymorphisms with knee osteoarthritis in Greek population. J Orthop Res (2008) 0.84

Therapeutically targeting microRNAs in liver cancer. Curr Pharm Des (2013) 0.84

Influence of interleukin 1alpha (IL-1alpha), IL-4, and IL-6 polymorphisms on genetic susceptibility to chronic osteomyelitis. Clin Vaccine Immunol (2008) 0.84

A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflamm Bowel Dis (2015) 0.83

Changes of blood biochemistry in the rabbit animal model in atherosclerosis research; a time- or stress-effect. Lipids Health Dis (2011) 0.83