Published in J Rheumatol on January 28, 2010
HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol (2011) 6.23
HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease. Nat Rev Rheumatol (2012) 2.75
The pulse of inflammation: heart rate variability, the cholinergic anti-inflammatory pathway and implications for therapy. J Intern Med (2011) 2.08
TLR-dependent T cell activation in autoimmunity. Nat Rev Immunol (2011) 1.88
HMGB1 in health and disease. Mol Aspects Med (2014) 1.67
High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus. Arthritis Res Ther (2011) 1.33
Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis. Arthritis Res Ther (2012) 1.17
Urine levels of HMGB1 in Systemic Lupus Erythematosus patients with and without renal manifestations. Arthritis Res Ther (2012) 1.08
Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-α and TNF-α in systemic lupus erythematosus. Rheumatol Int (2010) 1.03
Enhanced HMGB1 expression may contribute to Th17 cells activation in rheumatoid arthritis. Clin Dev Immunol (2011) 0.94
HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins. Cell Mol Immunol (2016) 0.89
Recent developments in the role of high-mobility group box 1 in systemic lupus erythematosus. Mol Med (2014) 0.87
Role of non-immune mechanisms of muscle damage in idiopathic inflammatory myopathies. Arthritis Res Ther (2012) 0.85
HMGB1 Promotes Systemic Lupus Erythematosus by Enhancing Macrophage Inflammatory Response. J Immunol Res (2015) 0.84
LPS may enhance expression and release of HMGB1 in human nasal epithelial cells in vitro. Acta Otorhinolaryngol Ital (2013) 0.82
Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus. Arthritis Res Ther (2015) 0.81
HMGB1: a dangerous player in lupus pathogenesis. J Rheumatol (2010) 0.80
The spectrum of anti-chromatin/nucleosome autoantibodies: independent and interdependent biomarkers of disease. J Immunol Res (2014) 0.79
High-mobility group box 1 (HMGB1) in childhood: from bench to bedside. Eur J Pediatr (2014) 0.78
Treatment with anti-HMGB1 monoclonal antibody does not affect lupus nephritis in MRL/lpr mice. Mol Med (2016) 0.77
A possible role of HMGB1 in DNA demethylation in CD4+ T cells from patients with systemic lupus erythematosus. Clin Dev Immunol (2013) 0.76
Lupus erythematosus revisited. Semin Immunopathol (2015) 0.76
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science (2012) 10.47
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
The specific and essential role of MAVS in antiviral innate immune responses. Immunity (2006) 6.74
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell (2010) 5.83
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37
A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature (2008) 4.76
Direct activation of protein kinases by unanchored polyubiquitin chains. Nature (2009) 4.65
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell (2012) 4.41
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet (2013) 3.51
The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet (2013) 3.43
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood (2011) 3.40
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature (2008) 3.11
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response. Immunity (2012) 3.07
Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA (2012) 2.49
Quantitative measurement of interocular suppression in anisometropic amblyopia: a case-control study. Ophthalmology (2013) 2.17
CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFα. Cell Stem Cell (2012) 1.97
Electronic signatures of all four DNA nucleosides in a tunneling gap. Nano Lett (2010) 1.83
MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers. J Allergy Clin Immunol (2012) 1.79
MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus. Proc Natl Acad Sci U S A (2008) 1.74
Clinical features and factors associated with severity and fatality among patients with severe fever with thrombocytopenia syndrome Bunyavirus infection in Northeast China. PLoS One (2013) 1.67
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife (2013) 1.63
Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters. Biochem Pharmacol (2009) 1.57
Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer (2002) 1.56
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet (2012) 1.49
A pair of allelic WRKY genes play opposite roles in rice-bacteria interactions. Plant Physiol (2009) 1.47
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project. Blood (2012) 1.47
A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. Cancer Res (2006) 1.46
Retroperitoneal laparoscopic dismembered pyeloplasty with a novel technique of JJ stenting in children. BJU Int (2011) 1.45
Decrease in rate of myopia progression with a contact lens designed to reduce relative peripheral hyperopia: one-year results. Invest Ophthalmol Vis Sci (2011) 1.41
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet (2010) 1.41
scFv-mediated delivery of truncated BID suppresses HER2-positive osteosarcoma growth and metastasis. Cancer Biol Ther (2008) 1.40
QDMR: a quantitative method for identification of differentially methylated regions by entropy. Nucleic Acids Res (2011) 1.37
High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders. J Allergy Clin Immunol (2013) 1.35
Manipulating broad-spectrum disease resistance by suppressing pathogen-induced auxin accumulation in rice. Plant Physiol (2010) 1.33
CD147/basigin promotes progression of malignant melanoma and other cancers. J Dermatol Sci (2010) 1.29
HHMD: the human histone modification database. Nucleic Acids Res (2009) 1.27
Wnt signaling in bone formation and its therapeutic potential for bone diseases. Ther Adv Musculoskelet Dis (2013) 1.25
DiseaseMeth: a human disease methylation database. Nucleic Acids Res (2011) 1.22
Improvement of Aspergillus sulphureus endo-beta-1,4-xylanase expression in Pichia pastoris by codon optimization and analysis of the enzymic characterization. Appl Biochem Biotechnol (2009) 1.22
miR-148a regulates osteoclastogenesis by targeting V-maf musculoaponeurotic fibrosarcoma oncogene homolog B. J Bone Miner Res (2013) 1.21
Rice gene network inferred from expression profiling of plants overexpressing OsWRKY13, a positive regulator of disease resistance. Mol Plant (2008) 1.17
Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance. Biochem Pharmacol (2008) 1.16
A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis. Cancer Lett (2008) 1.16
Anti-inflammatory effect of genistein on non-alcoholic steatohepatitis rats induced by high fat diet and its potential mechanisms. Int Immunopharmacol (2011) 1.14
OsWRKY45 alleles play different roles in abscisic acid signalling and salt stress tolerance but similar roles in drought and cold tolerance in rice. J Exp Bot (2011) 1.14
Spectacle lenses designed to reduce progression of myopia: 12-month results. Optom Vis Sci (2010) 1.13
Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome. Hum Reprod (2010) 1.13
Endogenous auxin and jasmonic acid levels are differentially modulated by abiotic stresses in rice. Front Plant Sci (2013) 1.12
Conditionally immortalized mouse embryonic fibroblasts retain proliferative activity without compromising multipotent differentiation potential. PLoS One (2012) 1.11
RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletion. Cancer Lett (2008) 1.10
A rice gene of de novo origin negatively regulates pathogen-induced defense response. PLoS One (2009) 1.10
Lapatinib and erlotinib are potent reversal agents for MRP7 (ABCC10)-mediated multidrug resistance. Biochem Pharmacol (2009) 1.09
Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10). PLoS One (2009) 1.09
Protective effect of Ulinastatin against murine models of sepsis: inhibition of TNF-α and IL-6 and augmentation of IL-10 and IL-13. Exp Toxicol Pathol (2010) 1.09
Defining how ubiquitin receptors hHR23a and S5a bind polyubiquitin. J Mol Biol (2007) 1.09
A sign-component-based framework for Chinese sign language recognition using accelerometer and sEMG data. IEEE Trans Biomed Eng (2012) 1.08
Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res (2012) 1.08
A genome-wide association analysis of Framingham Heart Study longitudinal data using multivariate adaptive splines. BMC Proc (2009) 1.08
DNA microarray-based identification of serogroups and virulence gene patterns of Escherichia coli isolates associated with porcine postweaning diarrhea and edema disease. Appl Environ Microbiol (2007) 1.07
Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1. J Biol Chem (2006) 1.07
Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors. BMC Cancer (2013) 1.06
Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier. Mol Vis (2007) 1.06
Preliminary characterization of the oral microbiota of Chinese adults with and without gingivitis. BMC Oral Health (2011) 1.05
Maximal conditional chi-square importance in random forests. Bioinformatics (2010) 1.04
Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells. BMC Cancer (2011) 1.04
The effectiveness of progressive addition lenses on the progression of myopia in Chinese children. Ophthalmic Physiol Opt (2009) 1.02
OsEDR1 negatively regulates rice bacterial resistance via activation of ethylene biosynthesis. Plant Cell Environ (2010) 1.02
Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria. J Am Chem Soc (2011) 1.01
Development of an O-antigen serotyping scheme for Cronobacter sakazakii. Appl Environ Microbiol (2011) 1.01
miR-33a functions as a tumor suppressor in melanoma by targeting HIF-1α. Cancer Biol Ther (2015) 1.00
Willows: a memory efficient tree and forest construction package. BMC Bioinformatics (2009) 1.00
A CCCH-type zinc finger nucleic acid-binding protein quantitatively confers resistance against rice bacterial blight disease. Plant Physiol (2011) 1.00
Protein kinase C isoforms differentially phosphorylate Ca(v)1.2 alpha(1c). Biochemistry (2009) 1.00
Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity. Exp Mol Med (2008) 1.00
Prevalence of virulence factors and antimicrobial resistance of uropathogenic Escherichia coli in Jiangsu province (China). Urology (2009) 0.99
BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci (2012) 0.99
CpG_MI: a novel approach for identifying functional CpG islands in mammalian genomes. Nucleic Acids Res (2009) 0.98
Acupuncture for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents. Cochrane Database Syst Rev (2011) 0.98
Proteomic analysis of strawberry leaves infected with Colletotrichum fragariae. J Proteomics (2012) 0.98
IL-13 receptor α1 differentially regulates aeroallergen-induced lung responses. J Immunol (2011) 0.98
Position-specific analysis and prediction for protein lysine acetylation based on multiple features. PLoS One (2012) 0.96
MicroRNA-17-92 cluster regulates osteoblast proliferation and differentiation. Endocrine (2013) 0.96
5-aminolevulinic acid alleviates the salinity-induced changes in Brassica napus as revealed by the ultrastructural study of chloroplast. Plant Physiol Biochem (2012) 0.96
Depletion of CD147 sensitizes human malignant melanoma cells to hydrogen peroxide-induced oxidative stress. J Dermatol Sci (2010) 0.96
RB1 gene inactivation by chromothripsis in human retinoblastoma. Oncotarget (2014) 0.96
CpG_MPs: identification of CpG methylation patterns of genomic regions from high-throughput bisulfite sequencing data. Nucleic Acids Res (2012) 0.96
An improved method to knock out the asd gene of Salmonella enterica serovar Pullorum. J Biomed Biotechnol (2009) 0.95
Genome-wide dynamic changes of DNA methylation of repetitive elements in human embryonic stem cells and fetal fibroblasts. Genomics (2011) 0.95
Automatic registration of CT volumes and dual-energy digital radiography for detection of cardiac and lung diseases. Conf Proc IEEE Eng Med Biol Soc (2006) 0.95
Proteomic and bioinformatic analysis on endocrine organs of domesticated silkworm, Bombyx mori L. for a comprehensive understanding of their roles and relations. J Proteome Res (2009) 0.95
Refractive shifts in four selected artificial vitreous substitutes based on Gullstrand-Emsley and Liou-Brennan schematic eyes. Invest Ophthalmol Vis Sci (2009) 0.95
Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biol (2012) 0.95
IGFBP5 domains exert distinct inhibitory effects on the tumorigenicity and metastasis of human osteosarcoma. Cancer Lett (2013) 0.94
Myopia progression in Chinese children is slower in summer than in winter. Optom Vis Sci (2012) 0.94
A local average connectivity-based method for identifying essential proteins from the network level. Comput Biol Chem (2011) 0.94
Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models. Phytother Res (2008) 0.94