PubRank

Jean-Marc Reichhart

Author PubWeight™ 53.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Immunity-related genes and gene families in Anopheles gambiae. Science 2002 5.47
2 Drosophila innate immunity: an evolutionary perspective. Nat Immunol 2002 4.61
3 Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 2005 3.22
4 Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors. Cell 2006 2.66
5 Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Nat Immunol 2007 2.36
6 Activation of Drosophila Toll during fungal infection by a blood serine protease. Science 2002 2.31
7 A serpin mutant links Toll activation to melanization in the host defence of Drosophila. EMBO J 2002 2.22
8 Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants. Proc Natl Acad Sci U S A 2002 2.04
9 The immune response of Drosophila melanogaster. Immunol Rev 2004 1.69
10 Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll. Nat Immunol 2008 1.54
11 Sensing and signaling during infection in Drosophila. Curr Opin Immunol 2005 1.49
12 Prophenoloxidase activation is not required for survival to microbial infections in Drosophila. EMBO Rep 2006 1.49
13 Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway. Immunity 2011 1.45
14 Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983. J Immunol 2012 1.38
15 Silencing of Toll pathway components by direct injection of double-stranded RNA into Drosophila adult flies. Nucleic Acids Res 2003 1.37
16 Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling. Mol Cell 2010 1.36
17 Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems. J Biol Chem 2010 1.32
18 A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens. Cell Host Microbe 2011 1.31
19 A serpin regulates dorsal-ventral axis formation in the Drosophila embryo. Curr Biol 2003 1.28
20 The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection. Cell Host Microbe 2013 1.20
21 Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions. J Biol Chem 2010 1.14
22 The multilayered innate immune defense of the gut. Biomed J 2015 1.10
23 Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni. PLoS Pathog 2010 1.07
24 Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. J Cell Sci 2009 1.06
25 Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila. EMBO Rep 2002 1.03
26 big bang gene modulates gut immune tolerance in Drosophila. Proc Natl Acad Sci U S A 2013 0.95
27 Toll-dependent and Toll-independent immune responses in Drosophila. J Endotoxin Res 2004 0.92
28 Drosophila necrotic mutations mirror disease-associated variants of human serpins. Development 2003 0.89
29 Specific versus non-specific immune responses in an invertebrate species evidenced by a comparative de novo sequencing study. PLoS One 2012 0.89
30 Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic. Insect Biochem Mol Biol 2005 0.88
31 Evolution and integration of innate immune systems from fruit flies to man: lessons and questions. J Endotoxin Res 2005 0.86
32 Structure-function analysis of grass clip serine protease involved in Drosophila Toll pathway activation. J Biol Chem 2011 0.84
33 TLR5 takes aim at bacterial propeller. Nat Immunol 2003 0.82