1
|
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene.
|
Am J Hum Genet
|
2000
|
4.42
|
2
|
Genome-wide association study of recurrent early-onset major depressive disorder.
|
Mol Psychiatry
|
2010
|
2.05
|
3
|
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.
|
Mol Psychiatry
|
2009
|
2.03
|
4
|
Sea urchin (lytechinus pictus) late-stage histone H3 and H4 genes: characterization and mapping of a clustered but nontandemly linked multigene family.
|
Cell
|
1982
|
1.69
|
5
|
TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa.
|
Nat Genet
|
1998
|
1.60
|
6
|
Genome-wide association study of obsessive-compulsive disorder.
|
Mol Psychiatry
|
2012
|
1.57
|
7
|
Genome-wide association study of Tourette's syndrome.
|
Mol Psychiatry
|
2012
|
1.42
|
8
|
Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes.
|
Proc Natl Acad Sci U S A
|
1997
|
1.36
|
9
|
BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives.
|
Eur Respir J
|
2002
|
1.31
|
10
|
Refinement of the spinal muscular atrophy locus to the interval between D5S435 and MAP1B.
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Genomics
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1993
|
1.28
|
11
|
BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease.
|
Eur Respir J
|
2004
|
1.28
|
12
|
Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta.
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Gene
|
1997
|
1.26
|
13
|
Investigation of serotonin-related genes in antidepressant response.
|
Mol Psychiatry
|
2004
|
1.26
|
14
|
Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective.
|
Psychol Med
|
2011
|
1.25
|
15
|
Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q.
|
Mol Psychiatry
|
2006
|
1.24
|
16
|
Fine mapping of PPH1, a gene for familial primary pulmonary hypertension, to a 3-cM region on chromosome 2q33.
|
Am J Respir Crit Care Med
|
2000
|
1.21
|
17
|
Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.
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Am J Med Genet B Neuropsychiatr Genet
|
2009
|
1.21
|
18
|
Potential panic disorder syndrome: clinical and genetic linkage evidence.
|
Am J Med Genet
|
2000
|
1.20
|
19
|
Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12.
|
Mol Psychiatry
|
2003
|
1.19
|
20
|
Central nervous system and cardiovascular effects of lorazepam in man.
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Clin Pharmacol Ther
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1971
|
1.17
|
21
|
Temporal expression of late histone messenger RNA in the sea urchin Lytechinus pictus.
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Proc Natl Acad Sci U S A
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1984
|
1.17
|
22
|
Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics.
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Am J Hum Genet
|
2001
|
1.13
|
23
|
Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics.
|
Mol Psychiatry
|
2004
|
1.13
|
24
|
Comparison of the late H1 histone genes of the sea urchins Lytechinus pictus and Strongelocentrotus purpuratus.
|
Nucleic Acids Res
|
1986
|
1.09
|
25
|
Tubby-like protein 1 homozygous splice-site mutation causes early-onset severe retinal degeneration.
|
Invest Ophthalmol Vis Sci
|
1999
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1.09
|
26
|
The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).
|
Genomics
|
1997
|
1.08
|
27
|
A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus.
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Am J Hum Genet
|
1999
|
1.07
|
28
|
Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder.
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Am J Med Genet
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2000
|
1.04
|
29
|
Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia.
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Eur Respir J
|
2004
|
1.03
|
30
|
A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families.
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Am J Med Genet B Neuropsychiatr Genet
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2009
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1.03
|
31
|
Clinical pharmacokinetics of lorazepam. II. Intramuscular injection.
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Clin Pharmacol Ther
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1977
|
1.02
|
32
|
Perils of gene mapping with microsatellite markers.
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Am J Hum Genet
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1992
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0.99
|
33
|
Obsessive-compulsive disorder: subclassification based on co-morbidity.
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Psychol Med
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2008
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0.97
|
34
|
Isolation, characterization, and expression of the gene encoding the late histone subtype H1-gamma of the sea urchin Strongylocentrotus purpuratus.
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Mol Cell Biol
|
1987
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0.97
|
35
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Clinical pharmacokinetics of lorazepam. III. Intravenous injection. Preliminary results.
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J Clin Pharmacol
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1977
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0.94
|
36
|
Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1.
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Am J Med Genet B Neuropsychiatr Genet
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2013
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0.93
|
37
|
Disposition of 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam) in humans. Determination of the drug by electron capture gas chromatography.
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Arzneimittelforschung
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1971
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0.93
|
38
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Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study.
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Mol Psychiatry
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2009
|
0.92
|
39
|
Absorption and excretion of 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one (oxazepam) in humans. Determination of the drug by gas-liquid chromatography with electron capture detection.
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Arzneimittelforschung
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1972
|
0.91
|
40
|
Breast milk: a source of more than nutrition for the neonate.
|
Clin Toxicol
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1974
|
0.90
|
41
|
Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder.
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Psychiatr Genet
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1999
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0.89
|
42
|
The deletion polymorphism and Val1000Ile in alpha-2-macroglobulin and Alzheimer disease in Caribbean Hispanics.
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Neurosci Lett
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2000
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0.85
|
43
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Fine genetic mapping of a gene for autosomal recessive retinitis pigmentosa on chromosome 6p21.
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Am J Hum Genet
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1995
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0.85
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44
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Disposition of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin) in beagle dogs and rhesus monkeys.
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Drug Metab Dispos
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1978
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0.85
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45
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Association between a catechol-o-methyltransferase polymorphism and obsessive-compulsive disorder in the Afrikaner population.
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J Affect Disord
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2001
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0.83
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46
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Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families.
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Am J Med Genet B Neuropsychiatr Genet
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2009
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0.81
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47
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Genetic aspects of pulmonary arterial hypertension.
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Ann Med
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2001
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0.81
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48
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Homeobox genes in obsessive-compulsive disorder.
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Am J Med Genet B Neuropsychiatr Genet
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2011
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0.81
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49
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Clinical pharmacokinetics of lorazepam. I. Absorption and disposition of oral 14C-lorazepam.
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Clin Pharmacol Ther
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1976
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0.81
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50
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Parent-of-origin effect in panic disorder.
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Am J Med Genet
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1999
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0.80
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51
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Pinworms--Incidence, predictability and treatment with thiabendazole.
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Calif Med
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1967
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0.80
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52
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High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p.
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Genome Res
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1997
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0.79
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53
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No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder.
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Mol Psychiatry
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2001
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0.77
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54
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D8/17 in obsessive-compulsive disorder and trichotillomania.
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S Afr Med J
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1999
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0.77
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55
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No genetic linkage or association between a functional promoter polymorphism in the monoamine oxidase-A gene and panic disorder.
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Mol Psychiatry
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2000
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0.77
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56
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Homozygosity and physical mapping of the autosomal recessive retinitis pigmentosa locus (RP14) on chromosome 6p21.3.
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Genomics
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1998
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0.77
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57
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Applications of pooled DNA samples to the assessment of population affinities: short tandem repeats.
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Hum Biol
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2005
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0.76
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58
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Bipolar disorder and chromosome 18p11: uncertainties redux.
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Psychiatr Genet
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2000
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0.76
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59
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Chromosome 18p11 and linkage to bipolar disorder revisited.
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Psychiatr Genet
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1999
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0.75
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60
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Investigation of dopamine receptor (DRD4) and dopamine transporter (DAT) polymorphisms for genetic linkage or association to panic disorder.
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Am J Med Genet
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2000
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0.75
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61
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Pulmonary alveolar proteinosis in an infant.
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East Afr Med J
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1981
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0.75
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62
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Oxaprozin disposition in renal disease.
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Clin Pharmacol Ther
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1982
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0.75
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63
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Effects on the infant of drug therapy in nursing mothers.
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Drug Ther (NY)
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1973
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0.75
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64
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Determination of promethazine in human plasma by automated high-performance liquid chromatography with electrochemical detection and by gas chromatography-mass spectrometry.
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J Chromatogr
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1985
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0.75
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65
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Cardiac electrophysiology of the antiarrhythmic agent recainam (Wy-42,362) in anesthetized dogs: relation to plasma and myocardial concentrations.
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J Cardiovasc Pharmacol
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1988
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0.75
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66
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Effects of food on oxaprozin bioavailability.
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J Clin Pharmacol
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1984
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0.75
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67
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Venereal disease in adolescence.
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Med Arts Sci
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1968
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0.75
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68
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Gas chromatographic determination of guanabenz in biological fluids by electron-capture detection.
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J Pharm Sci
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1982
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0.75
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69
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Macro- and micromethods for high-performance liquid chromatographic analysis of oxaprozin in plasma.
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J Pharm Sci
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1980
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0.75
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70
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Clinical pharmacokinetics of lorazepam. IV. Long-term oral administration.
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J Clin Pharmacol
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1977
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0.75
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71
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Diastereoisomeric glucuronides of oxazepam. Isolation and stereoselective enzymic hydrolysis.
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Drug Metab Dispos
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1979
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0.75
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72
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Determination of cycloleucine in biological fluids.
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Anal Biochem
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1969
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0.75
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73
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Effect of chronic renal failure on oxaprozin multiple-dose pharmacokinetics.
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Clin Pharmacol Ther
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1988
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0.75
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