Published in APMIS on February 01, 2010
Applying insights from biofilm biology to drug development - can a new approach be developed? Nat Rev Drug Discov (2013) 1.82
Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrob Agents Chemother (2011) 1.46
Biofilms and persistent wound infections in United States military trauma patients: a case-control analysis. BMC Infect Dis (2014) 1.02
Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model. PLoS One (2013) 0.86
A 1,000-Year-Old Antimicrobial Remedy with Antistaphylococcal Activity. MBio (2015) 0.84
A novel microfluidic wound model for testing antimicrobial agents against Staphylococcus pseudintermedius biofilms. J Nanobiotechnology (2014) 0.78
New insights in Staphylococcus pseudintermedius pathogenicity: antibiotic-resistant biofilm formation by a human wound-associated strain. BMC Microbiol (2015) 0.77
Gel-Entrapped Staphylococcus aureus Bacteria as Models of Biofilm Infection Exhibit Growth in Dense Aggregates, Oxygen Limitation, Antibiotic Tolerance, and Heterogeneous Gene Expression. Antimicrob Agents Chemother (2016) 0.76
Collagen and hyaluronan at wound sites influence early polymicrobial biofilm adhesive events. BMC Microbiol (2014) 0.76
Interspecific Bacterial Interactions are Reflected in Multispecies Biofilm Spatial Organization. Front Microbiol (2016) 0.75
A Novel Qualitative and Quantitative Biofilm Assay Based on 3D Soft Tissue. Int J Biomater (2014) 0.75
Chronic Wound Biofilm Model. Adv Wound Care (New Rochelle) (2015) 0.75
The efficacy of different anti-microbial metals at preventing the formation of, and eradicating bacterial biofilms of pathogenic indicator strains. J Antibiot (Tokyo) (2017) 0.75
Development of a novel collagen wound model to simulate the activity and distribution of antimicrobials in soft tissue during diabetic foot infection. Antimicrob Agents Chemother (2016) 0.75
Optimised chronic infection models demonstrate that siderophore 'cheating' in Pseudomonas aeruginosa is context specific. ISME J (2017) 0.75
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J (2003) 5.78
Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents (2010) 5.18
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol Microbiol (2006) 4.49
Cell death in Pseudomonas aeruginosa biofilm development. J Bacteriol (2003) 3.74
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology (2002) 3.37
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Mol Microbiol (2006) 2.94
Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol (2006) 2.68
Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen (2008) 2.58
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest (2003) 2.54
Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients. Pediatr Pulmonol (2009) 2.53
Mini-Tn7 transposons for site-specific tagging of bacteria with fluorescent proteins. Environ Microbiol (2004) 2.52
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology (2002) 2.41
Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms. Environ Microbiol (2008) 2.27
First case of E anophelis outbreak in an intensive-care unit. Lancet (2013) 2.26
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology (2005) 2.24
Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression. Appl Environ Microbiol (2002) 2.19
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector. J Bacteriol (2005) 2.09
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology (2009) 2.06
Pseudomonas aeruginosa biofilms in cystic fibrosis. Future Microbiol (2010) 2.06
Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05
Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa. Microbiology (2007) 2.05
Quorum sensing inhibitors: a bargain of effects. Microbiology (2006) 1.99
Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production. Antimicrob Agents Chemother (2004) 1.99
Food spoilage--interactions between food spoilage bacteria. Int J Food Microbiol (2002) 1.97
The clinical impact of bacterial biofilms. Int J Oral Sci (2011) 1.88
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology (2007) 1.88
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD. Antimicrob Agents Chemother (2002) 1.85
Applying insights from biofilm biology to drug development - can a new approach be developed? Nat Rev Drug Discov (2013) 1.82
Characterization of starvation-induced dispersion in Pseudomonas putida biofilms. Environ Microbiol (2005) 1.82
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model. J Antimicrob Chemother (2012) 1.81
The in vivo biofilm. Trends Microbiol (2013) 1.79
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice. Antimicrob Agents Chemother (2007) 1.71
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology (2005) 1.70
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis. Infect Immun (2005) 1.69
Bacterial biofilms: prokaryotic adventures in multicellularity. Curr Opin Microbiol (2003) 1.68
Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunol Med Microbiol (2010) 1.68
Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2008) 1.67
Identity and effects of quorum-sensing inhibitors produced by Penicillium species. Microbiology (2005) 1.67
Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system. J Bacteriol (2004) 1.67
Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111. Mol Microbiol (2002) 1.63
Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. J Bacteriol (2004) 1.62
Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model. J Infect Dis (2005) 1.62
Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds. J Clin Microbiol (2009) 1.55
In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections. J Bacteriol (2007) 1.46
Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants. Microbiology (2009) 1.45
Bacterial biofilm formation and treatment in soft tissue fillers. Pathog Dis (2014) 1.44
Towards diagnostic guidelines for biofilm-associated infections. FEMS Immunol Med Microbiol (2012) 1.43
Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients. PLoS One (2010) 1.42
Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF. Appl Environ Microbiol (2002) 1.40
The immune system vs. Pseudomonas aeruginosa biofilms. FEMS Immunol Med Microbiol (2010) 1.38
Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein. J Bacteriol (2006) 1.34
The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia. Mol Microbiol (2011) 1.34
Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics. Environ Microbiol (2003) 1.33
Silver against Pseudomonas aeruginosa biofilms. APMIS (2007) 1.33
Quorum sensing in Serratia. FEMS Microbiol Rev (2007) 1.32
Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS One (2011) 1.31
Quorum sensing antagonism from marine organisms. Mar Biotechnol (NY) (2007) 1.31
Quorum-sensing-directed protein expression in Serratia proteamaculans B5a. Microbiology (2003) 1.30
Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae. ISME J (2008) 1.28
Pyoverdine and PQS mediated subpopulation interactions involved in Pseudomonas aeruginosa biofilm formation. Mol Microbiol (2009) 1.26
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes. PLoS One (2013) 1.25
Fluorescence-based reporter for gauging cyclic di-GMP levels in Pseudomonas aeruginosa. Appl Environ Microbiol (2012) 1.24
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother (2012) 1.23
Detection of bacteria by fluorescence in situ hybridization in culture-negative soft tissue filler lesions. Dermatol Surg (2009) 1.23
Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection. Invest Ophthalmol Vis Sci (2004) 1.22
Presence of acylated homoserine lactones (AHLs) and AHL-producing bacteria in meat and potential role of AHL in spoilage of meat. Appl Environ Microbiol (2004) 1.22
The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa. Anal Bioanal Chem (2006) 1.22
Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic. Org Biomol Chem (2004) 1.21
Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors. Antimicrob Agents Chemother (2009) 1.19