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1
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New models of collaboration in genome-wide association studies: the Genetic Association Information Network.
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Nat Genet
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2007
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13.76
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2
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RNA sequencing: advances, challenges and opportunities.
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Nat Rev Genet
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2010
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8.96
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3
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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
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Nature
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2011
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7.43
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4
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Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.
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Nat Genet
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2008
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6.06
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5
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Direct RNA sequencing.
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Nature
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2009
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4.37
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6
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Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation.
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Cell
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2010
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3.42
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7
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RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis.
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Nature
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2012
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3.40
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8
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Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.
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Nat Methods
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2009
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2.26
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9
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Amplification-free digital gene expression profiling from minute cell quantities.
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Nat Methods
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2010
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2.07
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10
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Digital transcriptome profiling from attomole-level RNA samples.
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Genome Res
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2010
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1.83
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11
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New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism.
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Nature
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2010
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1.78
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12
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Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels.
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Hum Genomics
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2004
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1.71
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13
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An in-depth map of polyadenylation sites in cancer.
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Nucleic Acids Res
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2012
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1.71
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14
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A comparison of single molecule and amplification based sequencing of cancer transcriptomes.
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PLoS One
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2011
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1.44
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15
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Direct sequencing of Arabidopsis thaliana RNA reveals patterns of cleavage and polyadenylation.
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Nat Struct Mol Biol
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2012
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1.34
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16
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Protocol dependence of sequencing-based gene expression measurements.
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PLoS One
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2011
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1.19
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17
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Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes.
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Am Heart J
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2006
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1.12
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18
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Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels.
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Biochim Biophys Acta
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2004
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1.12
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19
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The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder.
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Psychopharmacology (Berl)
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2003
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1.09
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20
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Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing.
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Hum Gene Ther
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2011
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1.05
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21
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Role of a KCNH2 polymorphism (R1047 L) in dofetilide-induced Torsades de Pointes.
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J Mol Cell Cardiol
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2004
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1.05
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22
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CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease.
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Atherosclerosis
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2005
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1.04
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23
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Single-molecule sequencing: sequence methods to enable accurate quantitation.
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Methods Enzymol
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2010
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1.01
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24
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The properties and applications of single-molecule DNA sequencing.
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Genome Biol
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2011
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1.00
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25
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Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations.
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Genome Res
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2011
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0.99
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26
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Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests.
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Clin Pharmacol Ther
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2005
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0.98
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27
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Polymorphisms in the CETP gene and association with CETP mass and HDL levels.
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Atherosclerosis
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2003
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0.96
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28
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Single-molecule direct RNA sequencing without cDNA synthesis.
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Wiley Interdiscip Rev RNA
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2011
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0.95
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29
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On the importance of small changes in RNA expression.
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Methods
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2013
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0.85
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30
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Transcriptome profiling using single-molecule direct RNA sequencing.
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Methods Mol Biol
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2011
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0.85
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31
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Profiling of short RNAs using Helicos single-molecule sequencing.
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Methods Mol Biol
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2012
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0.81
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32
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Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.
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J Biol Chem
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2005
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0.81
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33
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Highly polymorphic repeat region in the CETP promoter induces unusual DNA structure.
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Biochim Biophys Acta
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2004
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0.79
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34
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RNA sequencing and quantitation using the Helicos Genetic Analysis System.
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Methods Mol Biol
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2011
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0.76
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35
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Helicos single-molecule sequencing of bacterial genomes.
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Methods Mol Biol
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2011
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0.75
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