Published in Nat Rev Genet on December 30, 2010
Genome-wide genetic marker discovery and genotyping using next-generation sequencing. Nat Rev Genet (2011) 9.26
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. Nucleic Acids Res (2012) 7.52
Next-generation transcriptome assembly. Nat Rev Genet (2011) 5.89
Recurrent R-spondin fusions in colon cancer. Nature (2012) 5.10
viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nat Biotechnol (2013) 4.88
PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions. Bioinformatics (2011) 4.50
RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nat Rev Drug Discov (2012) 3.70
Revisiting global gene expression analysis. Cell (2012) 3.63
Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells. Cell (2012) 3.26
Medulloblastomics: the end of the beginning. Nat Rev Cancer (2012) 3.01
The microglial sensome revealed by direct RNA sequencing. Nat Neurosci (2013) 2.73
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories. Nat Biotechnol (2013) 2.53
A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae. Nucleic Acids Res (2012) 2.53
Sequencing technologies and genome sequencing. J Appl Genet (2011) 2.52
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings. Cell Res (2012) 2.41
The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium. Proc Natl Acad Sci U S A (2012) 2.39
From single cells to deep phenotypes in cancer. Nat Biotechnol (2012) 2.12
Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. Annu Rev Immunol (2012) 2.06
RNA-Seq-based monitoring of infection-linked changes in Vibrio cholerae gene expression. Cell Host Microbe (2011) 2.05
RNA-seq differential expression studies: more sequence or more replication? Bioinformatics (2013) 1.87
Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress. Proc Natl Acad Sci U S A (2012) 1.80
Alternative polyadenylation: new insights from global analyses. RNA (2012) 1.72
Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. Nucleic Acids Res (2012) 1.66
Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency. Genome Res (2013) 1.64
A low-cost library construction protocol and data analysis pipeline for Illumina-based strand-specific multiplex RNA-seq. PLoS One (2011) 1.60
Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum. BMC Genomics (2011) 1.60
Expanding the computational toolbox for mining cancer genomes. Nat Rev Genet (2014) 1.60
Identification of microRNA-regulated gene networks by expression analysis of target genes. Genome Res (2012) 1.51
Deep sequencing the circadian and diurnal transcriptome of Drosophila brain. Genome Res (2012) 1.47
Characterization of a New DGKE Intronic Mutation in Genetically Unsolved Cases of Familial Atypical Hemolytic Uremic Syndrome. Clin J Am Soc Nephrol (2015) 1.45
High-resolution transcriptome of human macrophages. PLoS One (2012) 1.42
Evaluation of two commercial global miRNA expression profiling platforms for detection of less abundant miRNAs. BMC Genomics (2011) 1.39
RNA-Seq and human complex diseases: recent accomplishments and future perspectives. Eur J Hum Genet (2012) 1.38
Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. BMC Genomics (2015) 1.38
Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms. J Invest Dermatol (2014) 1.36
Single-neuron RNA-Seq: technical feasibility and reproducibility. Front Genet (2012) 1.32
Thermostable group II intron reverse transcriptase fusion proteins and their use in cDNA synthesis and next-generation RNA sequencing. RNA (2013) 1.29
Directional RNA deep sequencing sheds new light on the transcriptional response of Anabaena sp. strain PCC 7120 to combined-nitrogen deprivation. BMC Genomics (2011) 1.29
Microfluidic single-cell whole-transcriptome sequencing. Proc Natl Acad Sci U S A (2014) 1.28
CRAC: an integrated approach to the analysis of RNA-seq reads. Genome Biol (2013) 1.26
Clinical review: sepsis and septic shock--the potential of gene arrays. Crit Care (2012) 1.25
A High-Throughput Method for Illumina RNA-Seq Library Preparation. Front Plant Sci (2012) 1.20
Discovery and mass spectrometric analysis of novel splice-junction peptides using RNA-Seq. Mol Cell Proteomics (2013) 1.20
Catalyzing plant science research with RNA-seq. Front Plant Sci (2013) 1.19
Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science. Nat Biotechnol (2013) 1.18
A quality control system for profiles obtained by ChIP sequencing. Nucleic Acids Res (2013) 1.18
Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue. PLoS One (2012) 1.17
Fundamentals of vitamin D hormone-regulated gene expression. J Steroid Biochem Mol Biol (2013) 1.15
Identification of the zebrafish maternal and paternal transcriptomes. Development (2013) 1.14
Bioinformatics and systems biology of the lipidome. Chem Rev (2011) 1.14
Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT). Semin Cancer Biol (2012) 1.13
Navigating the rapids: the development of regulated next-generation sequencing-based clinical trial assays and companion diagnostics. Front Oncol (2014) 1.12
Corset: enabling differential gene expression analysis for de novo assembled transcriptomes. Genome Biol (2014) 1.12
The genetics and functional analysis of primary osteoarthritis susceptibility. Expert Rev Mol Med (2013) 1.10
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction. Genome Biol (2015) 1.10
The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector. G3 (Bethesda) (2013) 1.10
Comparative RNA-Seq and microarray analysis of gene expression changes in B-cell lymphomas of Canis familiaris. PLoS One (2013) 1.09
In silico prediction of splice-altering single nucleotide variants in the human genome. Nucleic Acids Res (2014) 1.08
Transcriptomic landscape of breast cancers through mRNA sequencing. Sci Rep (2012) 1.08
De novo assembly and characterization of the Barnyardgrass (Echinochloa crus-galli) transcriptome using next-generation pyrosequencing. PLoS One (2013) 1.08
The detection of microRNA associated with Alzheimer's disease in biological fluids using next-generation sequencing technologies. Front Genet (2013) 1.08
Integrating omic approaches for abiotic stress tolerance in soybean. Front Plant Sci (2014) 1.07
Response to copper stress in Streptomyces lividans extends beyond genes under direct control of a copper-sensitive operon repressor protein (CsoR). J Biol Chem (2012) 1.07
RNA sequencing: platform selection, experimental design, and data interpretation. Nucleic Acid Ther (2012) 1.07
Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare. Genet Sel Evol (2016) 1.07
Strand-specific libraries for high throughput RNA sequencing (RNA-Seq) prepared without poly(A) selection. Silence (2012) 1.07
Targeted enrichment of the black cottonwood (Populus trichocarpa) gene space using sequence capture. BMC Genomics (2012) 1.06
Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells. Springerplus (2016) 1.06
Individual RNA base recognition in immobilized oligonucleotides using a protein nanopore. Nano Lett (2012) 1.06
Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes. Nat Commun (2014) 1.05
Transcriptome profiling of the cancer, adjacent non-tumor and distant normal tissues from a colorectal cancer patient by deep sequencing. PLoS One (2012) 1.04
cDNA hybrid capture improves transcriptome analysis on low-input and archived samples. J Mol Diagn (2014) 1.03
Bridger: a new framework for de novo transcriptome assembly using RNA-seq data. Genome Biol (2015) 1.03
Expression changes of ribosomal proteins in phosphate- and iron-deficient Arabidopsis roots predict stress-specific alterations in ribosome composition. BMC Genomics (2013) 1.02
lncRNome: a comprehensive knowledgebase of human long noncoding RNAs. Database (Oxford) (2013) 1.02
Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions. Int J Parasitol Drugs Drug Resist (2014) 1.02
Classification of low quality cells from single-cell RNA-seq data. Genome Biol (2016) 1.01
New technologies for 21st century plant science. Plant Cell (2012) 1.01
Evaluating statistical analysis models for RNA sequencing experiments. Front Genet (2013) 1.01
A multivariate approach to the integration of multi-omics datasets. BMC Bioinformatics (2014) 1.01
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns. RNA (2013) 1.01
Targeted sequencing for gene discovery and quantification using RNA CaptureSeq. Nat Protoc (2014) 1.01
Alternative splicing: a potential source of functional innovation in the eukaryotic genome. Int J Evol Biol (2012) 1.00
Epigenomics of hypertension. Semin Nephrol (2013) 1.00
Pivots of pluripotency: the roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells. Biochim Biophys Acta (2012) 1.00
The challenges of delivering bioinformatics training in the analysis of high-throughput data. Brief Bioinform (2013) 1.00
Comprehensive analysis of RNA-seq data reveals the complexity of the transcriptome in Brassica rapa. BMC Genomics (2013) 1.00
Using next-generation RNA sequencing to identify imprinted genes. Heredity (Edinb) (2014) 0.99
Analysis of the Asian seabass transcriptome based on expressed sequence tags. DNA Res (2011) 0.99
Genome-Wide Gene Expression Profiling of Nucleus Accumbens Neurons Projecting to Ventral Pallidum Using both Microarray and Transcriptome Sequencing. Front Neurosci (2011) 0.99
Role of the retinal vascular endothelial cell in ocular disease. Prog Retin Eye Res (2012) 0.99
Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells. Autophagy (2014) 0.98
Functional transcriptomics in the post-ENCODE era. Genome Res (2013) 0.98
Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing. Genomics (2011) 0.97
Informatics for RNA Sequencing: A Web Resource for Analysis on the Cloud. PLoS Comput Biol (2015) 0.97
Transcriptional profiles of bovine in vivo pre-implantation development. BMC Genomics (2014) 0.97
An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations. J Bone Miner Res (2013) 0.97
Transcriptome sequencing reveals the character of incomplete dosage compensation across multiple tissues in flycatchers. Genome Biol Evol (2013) 0.96
Comparative analysis of response to selection with three insecticides in the dengue mosquito Aedes aegypti using mRNA sequencing. BMC Genomics (2014) 0.96
Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods (2008) 126.81
TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol (2010) 75.21
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet (2009) 58.77
Alternative isoform regulation in human tissue transcriptomes. Nature (2008) 52.76
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
Sequencing technologies - the next generation. Nat Rev Genet (2009) 40.57
Stem cell transcriptome profiling via massive-scale mRNA sequencing. Nat Methods (2008) 31.04
Paired-end mapping reveals extensive structural variation in the human genome. Science (2007) 30.46
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science (2008) 29.99
Real-time DNA sequencing from single polymerase molecules. Science (2008) 29.53
Substantial biases in ultra-short read data sets from high-throughput DNA sequencing. Nucleic Acids Res (2008) 26.36
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (2009) 20.75
Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs. Nat Biotechnol (2010) 18.44
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature (2009) 18.08
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science (2008) 16.48
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol (2008) 15.90
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
Small silencing RNAs: an expanding universe. Nat Rev Genet (2009) 13.88
Comprehensive human genome amplification using multiple displacement amplification. Proc Natl Acad Sci U S A (2002) 13.58
Statistical inferences for isoform expression in RNA-Seq. Bioinformatics (2009) 12.50
mRNA-Seq whole-transcriptome analysis of a single cell. Nat Methods (2009) 11.71
A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana. Genes Dev (2006) 11.71
Transcriptome sequencing to detect gene fusions in cancer. Nature (2009) 11.63
Divergent transcription from active promoters. Science (2008) 11.03
RNA-Seq gene expression estimation with read mapping uncertainty. Bioinformatics (2009) 10.74
Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of (G+C)-biased genomes. Nat Methods (2009) 10.41
The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer (2007) 9.81
Genome-wide transcription and the implications for genomic organization. Nat Rev Genet (2007) 9.45
Transcriptome analysis by strand-specific sequencing of complementary DNA. Nucleic Acids Res (2009) 9.40
Gene ontology analysis for RNA-seq: accounting for selection bias. Genome Biol (2010) 9.15
Comprehensive comparative analysis of strand-specific RNA sequencing methods. Nat Methods (2010) 9.09
Biases in Illumina transcriptome sequencing caused by random hexamer priming. Nucleic Acids Res (2010) 9.08
Expansion of the eukaryotic proteome by alternative splicing. Nature (2010) 8.84
Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage. Proc Natl Acad Sci U S A (2003) 8.73
Transcript length bias in RNA-seq data confounds systems biology. Biol Direct (2009) 8.53
Integrative analysis of the melanoma transcriptome. Genome Res (2010) 8.46
Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth. Proc Natl Acad Sci U S A (2007) 7.82
Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet (2007) 7.42
Genomic sequencing and methylation analysis by ligation mediated PCR. Science (1989) 7.38
Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science (2009) 6.96
Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs. Nature (2009) 6.88
Diversity of microRNAs in human and chimpanzee brain. Nat Genet (2006) 6.57
The antisense transcriptomes of human cells. Science (2008) 6.29
Analysis of gene expression in single live neurons. Proc Natl Acad Sci U S A (1992) 6.15
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science (2009) 6.07
Antisense artifacts in transcriptome microarray experiments are resolved by actinomycin D. Nucleic Acids Res (2007) 5.54
Chromatin structure analyses identify miRNA promoters. Genes Dev (2008) 5.40
Chimeric transcript discovery by paired-end transcriptome sequencing. Proc Natl Acad Sci U S A (2009) 5.30
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nat Med (2010) 4.81
DNA-directed DNA polymerase activity in oncogenic RNA viruses. Nature (1970) 4.81
Regulatory roles of natural antisense transcripts. Nat Rev Mol Cell Biol (2009) 4.48
Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human. Nat Methods (2009) 4.38
Direct RNA sequencing. Nature (2009) 4.37
Limitations and possibilities of small RNA digital gene expression profiling. Nat Methods (2009) 4.34
Tiny RNAs associated with transcription start sites in animals. Nat Genet (2009) 4.19
Quantification of the yeast transcriptome by single-molecule sequencing. Nat Biotechnol (2009) 3.86
Digital transcriptome profiling using selective hexamer priming for cDNA synthesis. Nat Methods (2009) 3.73
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature (2010) 3.55
FRT-seq: amplification-free, strand-specific transcriptome sequencing. Nat Methods (2010) 3.55
A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells. Science (2008) 3.52
Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation. Cell (2010) 3.42
Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments. Nucleic Acids Res (2010) 3.36
Systematic analysis of transcribed loci in ENCODE regions using RACE sequencing reveals extensive transcription in the human genome. Genome Biol (2008) 3.34
Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection. Nat Med (2007) 3.34
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. Mol Cell Biol (1989) 3.00
Virtual terminator nucleotides for next-generation DNA sequencing. Nat Methods (2009) 2.83
Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts. Genome Biol (2009) 2.65
Detection of single nucleotide variations in expressed exons of the human genome using RNA-Seq. Nucleic Acids Res (2009) 2.61
Laser-capture microdissection: opening the microscopic frontier to molecular analysis. Trends Genet (1998) 2.60
Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE. Genome Res (2008) 2.60
Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line. Proc Natl Acad Sci U S A (2009) 2.57
Reverse transcriptase template switching and false alternative transcripts. Genomics (2006) 2.38
Replication of individual DNA molecules under electronic control using a protein nanopore. Nat Nanotechnol (2010) 2.33
Global and unbiased detection of splice junctions from RNA-seq data. Genome Biol (2010) 2.32
Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscan. Nat Methods (2010) 2.30
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA. Nat Methods (2009) 2.26
Pervasive transcription constitutes a new level of eukaryotic genome regulation. EMBO Rep (2009) 2.22
A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nat Methods (2010) 2.14
Characterizing the mouse ES cell transcriptome with Illumina sequencing. Genomics (2008) 2.09
Amplification-free digital gene expression profiling from minute cell quantities. Nat Methods (2010) 2.07
When good transcripts go bad: artifactual RT-PCR 'splicing' and genome analysis. Bioessays (2008) 2.07
Linear mRNA amplification from as little as 5 ng total RNA for global gene expression analysis. Biotechniques (2004) 2.04
Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. Genome Biol (2010) 2.00
Second-strand cDNA synthesis: mRNA fragments as primers. Methods Enzymol (1987) 1.88
Digital transcriptome profiling from attomole-level RNA samples. Genome Res (2010) 1.83
Fidelity of DNA ligation: a novel experimental approach based on the polymerisation of libraries of oligonucleotides. Nucleic Acids Res (1998) 1.80
New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism. Nature (2010) 1.78
Options available for profiling small samples: a review of sample amplification technology when combined with microarray profiling. Nucleic Acids Res (2006) 1.74
Replicase activity of purified recombinant protein P2 of double-stranded RNA bacteriophage phi6. EMBO J (2000) 1.71
Fixing the front end. Nat Biotechnol (2008) 1.70
Next generation sequencing of microbial transcriptomes: challenges and opportunities. FEMS Microbiol Lett (2009) 1.66
Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts. PLoS One (2009) 1.47
Global analysis of trans-splicing in Drosophila. Proc Natl Acad Sci U S A (2010) 1.47
Polyadenylation and degradation of incomplete RNA polymerase I transcripts in mammalian cells. EMBO Rep (2010) 1.43
Reverse transcriptase template switching during reverse transcriptase-polymerase chain reaction: artificial generation of deletions in ribonucleotide reductase mRNA. J Lab Clin Med (2001) 1.39
Reverse transcriptase adds nontemplated nucleotides to cDNAs during 5'-RACE and primer extension. Biotechniques (2001) 1.29
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature (2011) 7.43
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet (2008) 6.06
Direct RNA sequencing. Nature (2009) 4.37
Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation. Cell (2010) 3.42
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature (2012) 3.40
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA. Nat Methods (2009) 2.26
Amplification-free digital gene expression profiling from minute cell quantities. Nat Methods (2010) 2.07
Digital transcriptome profiling from attomole-level RNA samples. Genome Res (2010) 1.83
New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism. Nature (2010) 1.78
Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels. Hum Genomics (2004) 1.71
An in-depth map of polyadenylation sites in cancer. Nucleic Acids Res (2012) 1.71
A comparison of single molecule and amplification based sequencing of cancer transcriptomes. PLoS One (2011) 1.44
Direct sequencing of Arabidopsis thaliana RNA reveals patterns of cleavage and polyadenylation. Nat Struct Mol Biol (2012) 1.34
Protocol dependence of sequencing-based gene expression measurements. PLoS One (2011) 1.19
Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes. Am Heart J (2006) 1.12
Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels. Biochim Biophys Acta (2004) 1.12
The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder. Psychopharmacology (Berl) (2003) 1.09
Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing. Hum Gene Ther (2011) 1.05
Role of a KCNH2 polymorphism (R1047 L) in dofetilide-induced Torsades de Pointes. J Mol Cell Cardiol (2004) 1.05
CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease. Atherosclerosis (2005) 1.04
Single-molecule sequencing: sequence methods to enable accurate quantitation. Methods Enzymol (2010) 1.01
The properties and applications of single-molecule DNA sequencing. Genome Biol (2011) 1.00
Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations. Genome Res (2011) 0.99
Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests. Clin Pharmacol Ther (2005) 0.98
Polymorphisms in the CETP gene and association with CETP mass and HDL levels. Atherosclerosis (2003) 0.96
Single-molecule direct RNA sequencing without cDNA synthesis. Wiley Interdiscip Rev RNA (2011) 0.95
On the importance of small changes in RNA expression. Methods (2013) 0.85
Transcriptome profiling using single-molecule direct RNA sequencing. Methods Mol Biol (2011) 0.85
Profiling of short RNAs using Helicos single-molecule sequencing. Methods Mol Biol (2012) 0.81
Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib. J Biol Chem (2005) 0.81
Highly polymorphic repeat region in the CETP promoter induces unusual DNA structure. Biochim Biophys Acta (2004) 0.79
RNA sequencing and quantitation using the Helicos Genetic Analysis System. Methods Mol Biol (2011) 0.76
Helicos single-molecule sequencing of bacterial genomes. Methods Mol Biol (2011) 0.75