In vitro and in vivo evaluation of fenofibrate solid dispersion prepared by hot-melt extrusion.

Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation. AAPS PharmSciTech (2015) 0.98

Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt extrusion technology. AAPS PharmSciTech (2012) 0.88

Preparation and characterization of fenofibrate-loaded nanostructured lipid carriers for oral bioavailability enhancement. AAPS PharmSciTech (2014) 0.87

In vitro lipolysis data does not adequately predict the in vivo performance of lipid-based drug delivery systems containing fenofibrate. AAPS J (2014) 0.80

Application of carrier and plasticizer to improve the dissolution and bioavailability of poorly water-soluble baicalein by hot melt extrusion. AAPS PharmSciTech (2014) 0.78

Induction of pluripotency in mouse somatic cells with lineage specifiers. Cell (2013) 2.69

Messenger RNA expression levels of CXCR4 correlate with metastatic behavior and outcome in patients with osteosarcoma. Clin Cancer Res (2005) 2.31

Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway. Cancer Res (2004) 1.93

BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML. Blood (2006) 1.89

Predicting catastrophes in nonlinear dynamical systems by compressive sensing. Phys Rev Lett (2011) 1.61

AutismKB: an evidence-based knowledgebase of autism genetics. Nucleic Acids Res (2011) 1.59

Spontaneous breathing with biphasic positive airway pressure attenuates lung injury in hydrochloric acid-induced acute respiratory distress syndrome. Anesthesiology (2014) 1.53

Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma. Int J Cancer (2004) 1.48

Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas. Cancer Res (2012) 1.46

A half-log increase in BCR-ABL RNA predicts a higher risk of relapse in patients with chronic myeloid leukemia with an imatinib-induced complete cytogenetic response. Clin Cancer Res (2007) 1.41

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas. Oncotarget (2014) 1.40

Overexpression of long non-coding RNA MALAT1 is correlated with clinical progression and unfavorable prognosis in pancreatic cancer. Tumour Biol (2014) 1.33

Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts. Infect Immun (2003) 1.29

An overview of liposome lyophilization and its future potential. J Control Release (2009) 1.20

Solid lipid nanoparticles (SLNs) to improve oral bioavailability of poorly soluble drugs. J Pharm Pharmacol (2004) 1.15

Development of a dissolution medium for nimodipine tablets based on bioavailability evaluation. Eur J Pharm Sci (2004) 1.12

Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. Ann Hematol (2010) 1.11

Mitochondrial and chloroplast phylogeography of Picea crassifolia Kom. (Pinaceae) in the Qinghai-Tibetan Plateau and adjacent highlands. Mol Ecol (2007) 1.10

Discovery of a distinct superfamily of Kunitz-type toxin (KTT) from tarantulas. PLoS One (2008) 1.10

Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease. Int Immunol (2009) 1.09

Genetically transforming human mesenchymal stem cells to sarcomas: changes in cellular phenotype and multilineage differentiation potential. Cancer (2009) 1.08

Elevated physiologic tumor pressure promotes proliferation and chemosensitivity in human osteosarcoma. Clin Cancer Res (2005) 1.08

Development of a chemically stable 10-hydroxycamptothecin nanosuspensions. Int J Pharm (2009) 1.07

Applications of diffusion-weighted MRI in thoracic spinal cord injury without radiographic abnormality. Int Orthop (2006) 1.07

[Preparation and in vitro and in vivo evaluation of etoposide submicro-emulsion for intravenous injection]. Yao Xue Xue Bao (2007) 1.07

Bioavailability study of berberine and the enhancing effects of TPGS on intestinal absorption in rats. AAPS PharmSciTech (2011) 1.06

Preparation of estradiol chitosan nanoparticles for improving nasal absorption and brain targeting. Eur J Pharm Biopharm (2008) 1.06

A simple and rapid method for detection of Goose Parvovirus in the field by loop-mediated isothermal amplification. Virol J (2010) 1.04

Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease. Neurosci Lett (2011) 1.04

The immunoglobulin G subclass distribution of anti-GBM autoantibodies against rHalpha3(IV)NC1 is associated with disease severity. Hum Immunol (2009) 1.03

Transcriptome analysis of the venom glands of the Chinese wolf spider Lycosa singoriensis. Zoology (Jena) (2009) 1.03

Common genetic risk factors for venous thrombosis in the Chinese population. Am J Hum Genet (2013) 1.01

Circulating anti-glomerular basement membrane autoantibodies against α3(IV)NC1 undetectable by commercially available enzyme-linked immunosorbent assays. Nephrology (Carlton) (2012) 0.99

Influence of drought intensity on the response of six woody karst species subjected to successive cycles of drought and rewatering. Physiol Plant (2009) 0.99

A novel method for assessing sex-specific and genotype-specific response to injury in astrocyte culture. J Neurosci Methods (2008) 0.98

Part I: characterization of solid dispersions of nimodipine prepared by hot-melt extrusion. Drug Dev Ind Pharm (2007) 0.97

Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases. J Neurochem (2005) 0.96

Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression. Neurosci Lett (2010) 0.96

Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+ Th/Treg cell subset imbalance in ankylosing spondylitis. Arthritis Res Ther (2011) 0.96

Tumor interstitial fluid pressure may regulate angiogenic factors in osteosarcoma. J Orthop Res (2008) 0.96

Clinical outcome and risk factors for mortality in Chinese patients with diabetes on peritoneal dialysis: a 5-year clinical cohort study. Diabetes Res Clin Pract (2013) 0.95

Baicalein is neuroprotective in rat MCAO model: role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2. Pharmacol Biochem Behav (2010) 0.95

Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia. Brain Res (2010) 0.95

Antibodies against linear epitopes on the Goodpasture autoantigen and kidney injury. Clin J Am Soc Nephrol (2012) 0.94

Cathepsin B contributes to traumatic brain injury-induced cell death through a mitochondria-mediated apoptotic pathway. J Neurosci Res (2010) 0.94

Stability and degradation kinetics of etoposide-loaded parenteral lipid emulsion. J Pharm Sci (2007) 0.94

Expression of microRNA-96 and its potential functions by targeting FOXO3 in non-small cell lung cancer. Tumour Biol (2014) 0.93

Lipopolysaccharide-induced epididymitis disrupts epididymal beta-defensin expression and inhibits sperm motility in rats. Biol Reprod (2010) 0.93

Anti-glomerular basement membrane autoantibodies against different target antigens are associated with disease severity. Kidney Int (2009) 0.93

Avian reovirus triggers autophagy in primary chicken fibroblast cells and Vero cells to promote virus production. Arch Virol (2012) 0.93

Dexamethasone enhances cell resistance to chemotherapy by increasing adhesion to extracellular matrix in human ovarian cancer cells. Endocr Relat Cancer (2010) 0.93

Nimodipine semi-solid capsules containing solid dispersion for improving dissolution. Int J Pharm (2008) 0.92

Genetic diversity of the endemic and medicinally important plant Rheum officinale as revealed by Inter-Simpe Sequence Repeat (ISSR) Markers. Int J Mol Sci (2012) 0.92

Anti-inflammatory activity of myricetin isolated from Myrica rubra Sieb. et Zucc. leaves. Planta Med (2010) 0.92

Genetic background analysis of protein C deficiency demonstrates a recurrent mutation associated with venous thrombosis in Chinese population. PLoS One (2012) 0.92

Prediction of outcome of extracorporeal shock wave lithotripsy in the management of ureteric calculi. Urol Res (2010) 0.92

Proteomic and peptidomic characterization of the venom from the Chinese bird spider, Ornithoctonus huwena Wang. J Proteome Res (2007) 0.92

Association of epitope spreading of antiglomerular basement membrane antibodies and kidney injury. Clin J Am Soc Nephrol (2012) 0.92

Graphene oxide can induce in vitro and in vivo mutagenesis. Sci Rep (2013) 0.92

Tryptophan inhibits Proteus vulgaris TnaC leader peptide elongation, activating tna operon expression. J Bacteriol (2009) 0.90

Induction of small G protein RhoB by non-genotoxic stress inhibits apoptosis and activates NF-κB. J Cell Physiol (2011) 0.90

Genetic variation in Rheum palmatum and Rheum tanguticum (Polygonaceae), two medicinally and endemic species in China using ISSR markers. PLoS One (2012) 0.90

Refining timed pregnancies in two strains of genetically engineered mice. Lab Anim (NY) (2009) 0.90

Increased dissolution and oral absorption of itraconazole/Soluplus extrudate compared with itraconazole nanosuspension. Eur J Pharm Biopharm (2013) 0.90

New intrinsic mechanism on gum-like superelasticity of multifunctional alloys. Sci Rep (2013) 0.89

N-stearoyl-L-tyrosine ameliorates sevoflurane induced neuroapoptosis via MEK/ERK1/2 MAPK signaling pathway in the developing brain. Neurosci Lett (2013) 0.89

A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: design, in vitro and 'in vivo' evaluation. Int J Pharm (2007) 0.89

2-(Substituted phenyl)-3,4-dihydroisoquinolin-2-iums as novel antifungal lead compounds: biological evaluation and structure-activity relationships. Molecules (2013) 0.88

Evaluation of brain-targeting for the nasal delivery of ergoloid mesylate by the microdialysis method in rats. Eur J Pharm Biopharm (2007) 0.88

Retain singleton or twins? Multifetal pregnancy reduction strategies in triplet pregnancies with monochorionic twins. Eur J Obstet Gynecol Reprod Biol (2012) 0.88

Novel association of a PROC variant with ischemic stroke in a Chinese Han population. Hum Genet (2012) 0.88

FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese. Nephrol Dial Transplant (2009) 0.87

Preparation and in vitro/in vivo evaluation of sustained-release metformin hydrochloride pellets. Eur J Pharm Biopharm (2006) 0.87

Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability. Brain Res (2010) 0.87

Upregulations of glucocorticoid-induced leucine zipper by hypoxia and glucocorticoid inhibit proinflammatory cytokines under hypoxic conditions in macrophages. J Immunol (2011) 0.87

Autographa californica multiple nucleopolyhedrovirus odv-e66 is an essential gene required for oral infectivity. Virus Res (2011) 0.87

Autographa californica multiple nucleopolyhedrovirus odv-e25 (Ac94) is required for budded virus infectivity and occlusion-derived virus formation. Arch Virol (2012) 0.87

N-(Acetamido)thiourea based simple neutral hydrogen-bonding receptors for anions. Org Biomol Chem (2009) 0.87

p55PIK-PI3K stimulates angiogenesis in colorectal cancer cell by activating NF-κB pathway. Angiogenesis (2013) 0.87

IL-17A facilitates platelet function through the ERK2 signaling pathway in patients with acute coronary syndrome. PLoS One (2012) 0.87

Bombyx mori nucleopolyhedrovirus BmP95 plays an essential role in budded virus production and nucleocapsid assembly. J Gen Virol (2013) 0.86

Prevalence and risk factors for diabetic retinopathy in a high-risk Chinese population. BMC Public Health (2013) 0.86

Formulation and characterization of bufadienolides-loaded nanostructured lipid carriers. Drug Dev Ind Pharm (2010) 0.86

Preparation and in vitro-in vivo evaluation of double layer coated and matrix sustained release pellet formulations of diclofenac potassium. Int J Pharm (2011) 0.86

Evaluation of docetaxel-loaded intravenous lipid emulsion: pharmacokinetics, tissue distribution, antitumor activity, safety and toxicity. Pharm Res (2010) 0.86

Neuroprotection and underlying mechanisms of oxymatrine in cerebral ischemia of rats. Neurol Res (2010) 0.86

Proliferation and phenotypic changes of stromal cells in response to varying estrogen/androgen levels in castrated rats. Asian J Androl (2009) 0.86

Basins of attraction for species extinction and coexistence in spatial rock-paper-scissors games. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 0.85

Formulation, preparation and evaluation of an intravenous emulsion containing Brucea javanica oil and Coix Seed oil for anti-tumor application. Biol Pharm Bull (2008) 0.85

Effects and safety of allogenic mesenchymal stem cell intravenous infusion in active ankylosing spondylitis patients who failed NSAIDs: a 20-week clinical trial. Cell Transplant (2013) 0.85

Formulation of an intravenous emulsion loaded with a clarithromycin-phospholipid complex and its pharmacokinetics in rats. Int J Pharm (2008) 0.85

Real-time quantitative RT-PCR assay of prostate-specific antigen and prostate-specific membrane antigen in peripheral blood for detection of prostate cancer micrometastasis. Urol Oncol (2008) 0.85

The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke. Brain Res Bull (2010) 0.85

Simultaneous determination of three bufadienolides in rat plasma after intravenous administration of bufadienolides extract by ultra performance liquid chromatography electrospray ionization tandem mass spectrometry. Anal Chim Acta (2008) 0.85

The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients. BMC Nephrol (2011) 0.84

The properties of bufadienolides-loaded nano-emulsion and submicro-emulsion during lyophilization. Int J Pharm (2007) 0.84

Proteomic analysis of peritrophic membrane (PM) from the midgut of fifth-instar larvae, Bombyx mori. Mol Biol Rep (2011) 0.84

Development and validation of a tuberculosis medication adherence scale. PLoS One (2012) 0.84

Aerosolised surfactant generated by a novel noninvasive apparatus reduced acute lung injury in rats. Crit Care (2009) 0.84