Published in Dermatol Ther on February 08, 2010
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Neuroendocrine nicotinic receptor activation increases susceptibility to bacterial infections by suppressing antimicrobial peptide production. Cell Host Microbe (2010) 2.39
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Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin. FASEB J (2006) 2.33
Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe (2010) 2.28
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Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection. J Invest Dermatol (2005) 2.19
The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury. Immunity (2012) 2.17
Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum. J Immunol (2004) 2.16
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol (2010) 2.13
D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion. J Bacteriol (2005) 2.04
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Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proc Natl Acad Sci U S A (2004) 2.00
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem (2009) 1.91
Cathelicidin deficiency predisposes to eczema herpeticum. J Allergy Clin Immunol (2006) 1.88
Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli. Immunology (2006) 1.88
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Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol (2005) 1.86
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. J Exp Med (2010) 1.85
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Neutrophil-derived cathelicidin protects from neointimal hyperplasia. Sci Transl Med (2011) 1.84
Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res (2013) 1.80
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M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. J Innate Immun (2009) 1.80
Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. J Immunol (2003) 1.79
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. J Invest Dermatol (2010) 1.79
The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury. J Invest Dermatol (2008) 1.79
Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. J Immunol (2005) 1.78
Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol (2010) 1.77
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense. J Immunol (2004) 1.74
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest (2007) 1.72
Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol (2003) 1.70
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Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med (2012) 1.68
Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles. J Invest Dermatol (2013) 1.68
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function. Eur J Immunol (2011) 1.67
The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. FASEB J (2006) 1.66
Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens. Infect Immun (2005) 1.60
Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgaris. J Invest Dermatol (2008) 1.55
Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis. J Invest Dermatol (2005) 1.54
Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes. J Invest Dermatol (2009) 1.52
The microbiome extends to subepidermal compartments of normal skin. Nat Commun (2013) 1.52
Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. Gastroenterology (2003) 1.51
Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies. J Invest Dermatol (2005) 1.48
Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin. J Invest Dermatol (2002) 1.47
Adrenocorticotropin hormone stimulates interleukin-18 expression in human HaCaT keratinocytes. J Invest Dermatol (2007) 1.45
Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. J Immunol (2007) 1.42
Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection. Infect Immun (2006) 1.41
The molecular pathology of rosacea. J Dermatol Sci (2009) 1.41
Lack of neutrophil-derived CRAMP reduces atherosclerosis in mice. Circ Res (2012) 1.38
Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus. PLoS One (2013) 1.38
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum. J Allergy Clin Immunol (2010) 1.38
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis. J Cell Biol (2007) 1.36
Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol (2009) 1.35
Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol (2011) 1.34
Cathelicidins and innate defense against invasive bacterial infection. Scand J Infect Dis (2003) 1.33
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2007) 1.33
A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J (2008) 1.31
IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes. J Immunol (2008) 1.31
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Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection. Proc Natl Acad Sci U S A (2005) 1.26
Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. J Invest Dermatol (2008) 1.26
Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression. J Invest Dermatol (2009) 1.23
Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells. Blood (2013) 1.23
Functions of the skin microbiota in health and disease. Semin Immunol (2013) 1.22
Structural and sequence motifs in dermatan sulfate for promoting fibroblast growth factor-2 (FGF-2) and FGF-7 activity. J Biol Chem (2004) 1.22
Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases. Eur J Gastroenterol Hepatol (2006) 1.21
Cathelicidin-related antimicrobial peptide is required for effective lung mucosal immunity in Gram-negative bacterial pneumonia. J Immunol (2012) 1.20
Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin. J Immunol (2008) 1.20
TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol (2010) 1.18
Antimicrobial peptides in human skin disease. Eur J Dermatol (2007) 1.17
Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus. PLoS One (2010) 1.17
M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. J Mol Med (Berl) (2009) 1.17
Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol (2009) 1.16
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Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7). J Biol Chem (2002) 1.11
Developmental switch of intestinal antimicrobial peptide expression. J Exp Med (2008) 1.11
Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J Invest Dermatol (2010) 1.09
Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands. J Invest Dermatol (2011) 1.09