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1
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The molecular biology of head and neck cancer.
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Nat Rev Cancer
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2010
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9.84
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2
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Detection, clinical relevance and specific biological properties of disseminating tumour cells.
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Nat Rev Cancer
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2008
|
7.99
|
|
3
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Dissecting the metastatic cascade.
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Nat Rev Cancer
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2004
|
6.32
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|
4
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A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications.
|
Cancer Res
|
2003
|
5.04
|
|
5
|
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen.
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Int J Cancer
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2007
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4.29
|
|
6
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Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus.
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J Natl Cancer Inst
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2004
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3.67
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|
7
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BAC to the future! or oligonucleotides: a perspective for micro array comparative genomic hybridization (array CGH).
|
Nucleic Acids Res
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2006
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3.32
|
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8
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Outcome of patients with early stage oral cancer managed by an observation strategy towards the N0 neck using ultrasound guided fine needle aspiration cytology: No survival difference as compared to elective neck dissection.
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Oral Oncol
|
2012
|
2.08
|
|
9
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Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions.
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Head Neck
|
2002
|
1.41
|
|
10
|
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients.
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J Natl Cancer Inst
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2008
|
1.36
|
|
11
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A genetic progression model of oral cancer: current evidence and clinical implications.
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J Oral Pathol Med
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2004
|
1.36
|
|
12
|
Advances and applications of oral cancer basic research.
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Oral Oncol
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2011
|
1.33
|
|
13
|
Increasing prevalence rates of HPV attributable oropharyngeal squamous cell carcinomas in the Netherlands as assessed by a validated test algorithm.
|
Int J Cancer
|
2012
|
1.31
|
|
14
|
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.
|
Clin Cancer Res
|
2004
|
1.24
|
|
15
|
CGHMultiArray: exact P-values for multi-array comparative genomic hybridization data.
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Bioinformatics
|
2005
|
1.23
|
|
16
|
Multiple head and neck tumors frequently originate from a single preneoplastic lesion.
|
Am J Pathol
|
2002
|
1.20
|
|
17
|
Expanding fields of genetically altered cells in head and neck squamous carcinogenesis.
|
Semin Cancer Biol
|
2005
|
1.20
|
|
18
|
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
|
Clin Cancer Res
|
2009
|
1.19
|
|
19
|
Genetically altered fields as origin of locally recurrent head and neck cancer: a retrospective study.
|
Clin Cancer Res
|
2004
|
1.18
|
|
20
|
Human papilloma virus in head and neck cancer: the need for a standardised assay to assess the full clinical importance.
|
Eur J Cancer
|
2009
|
1.14
|
|
21
|
Comparative molecular and histological grading of epithelial dysplasia of the oral cavity and the oropharynx.
|
J Pathol
|
2003
|
1.13
|
|
22
|
Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma.
|
Int J Cancer
|
2003
|
1.12
|
|
23
|
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients.
|
Cancer Res
|
2005
|
1.12
|
|
24
|
Mutated p53 as a molecular marker for the diagnosis of head and neck cancer.
|
J Pathol
|
2002
|
1.11
|
|
25
|
Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis.
|
Cell Oncol
|
2009
|
1.10
|
|
26
|
Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma.
|
Clin Cancer Res
|
2011
|
1.08
|
|
27
|
Genetic reprogramming of tumor cells by zinc finger transcription factors.
|
Proc Natl Acad Sci U S A
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2005
|
1.07
|
|
28
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High-risk human papillomavirus-positive lung cancer: molecular evidence for a pattern of pulmonary metastasis.
|
J Thorac Oncol
|
2013
|
1.06
|
|
29
|
A noninvasive genetic screening test to detect oral preneoplastic lesions.
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Lab Invest
|
2005
|
1.06
|
|
30
|
Second field tumors: a new opportunity for cancer prevention?
|
Oncologist
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2005
|
1.01
|
|
31
|
Time trends in the prevalence of HPV in oropharyngeal squamous cell carcinomas in northern Spain (1990-2009).
|
Int J Cancer
|
2013
|
1.01
|
|
32
|
DNA quality assessment for array CGH by isothermal whole genome amplification.
|
Cell Oncol
|
2007
|
0.99
|
|
33
|
Protein biomarker discovery for head and neck cancer.
|
J Proteomics
|
2010
|
0.99
|
|
34
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Genome-wide microarray gene expression, array-CGH analysis, and telomerase activity in advanced ovarian endometriosis: a high degree of differentiation rather than malignant potential.
|
Int J Mol Med
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2008
|
0.97
|
|
35
|
Immortalization of oral keratinocytes by functional inactivation of the p53 and pRb pathways.
|
Int J Cancer
|
2010
|
0.97
|
|
36
|
Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue.
|
Oral Oncol
|
2010
|
0.96
|
|
37
|
Clinical significance of micrometastatic cells detected by E48 (Ly-6D) reverse transcription-polymerase chain reaction in bone marrow of head and neck cancer patients.
|
Clin Cancer Res
|
2004
|
0.96
|
|
38
|
Using tissue adjacent to carcinoma as a normal control: an obvious but questionable practice.
|
J Pathol
|
2004
|
0.95
|
|
39
|
Molecular characterization of p16-immunopositive but HPV DNA-negative oropharyngeal carcinomas.
|
Int J Cancer
|
2013
|
0.95
|
|
40
|
Wait-and-see policy for the N0 neck in early-stage oral and oropharyngeal squamous cell carcinoma using ultrasonography-guided cytology: is there a role for identification of the sentinel node?
|
Head Neck
|
2002
|
0.94
|
|
41
|
Evaluation of cornulin, keratin 4, keratin 13 expression and grade of dysplasia for predicting malignant progression of oral leukoplakia.
|
Oral Oncol
|
2009
|
0.94
|
|
42
|
Novel diagnostic modalities for assessment of the clinically node-negative neck in oral squamous-cell carcinoma.
|
Lancet Oncol
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2012
|
0.93
|
|
43
|
Status of primary tumour surgical margins in squamous head and neck cancer: prognostic implications.
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Curr Opin Otolaryngol Head Neck Surg
|
2007
|
0.91
|
|
44
|
Gene expression profiling in head and neck squamous cell carcinoma.
|
Curr Opin Otolaryngol Head Neck Surg
|
2010
|
0.91
|
|
45
|
Validation of a gene expression signature for assessment of lymph node metastasis in oral squamous cell carcinoma.
|
J Clin Oncol
|
2012
|
0.90
|
|
46
|
Circulating invariant natural killer T-cell numbers predict outcome in head and neck squamous cell carcinoma: updated analysis with 10-year follow-up.
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J Clin Oncol
|
2012
|
0.90
|
|
47
|
Screening for oral precancer with noninvasive genetic cytology.
|
Cancer Prev Res (Phila)
|
2009
|
0.90
|
|
48
|
Assessment and clinical significance of micrometastases in lymph nodes of head and neck cancer patients detected by E48 (Ly-6D) quantitative reverse transcription-polymerase chain reaction.
|
Lab Invest
|
2003
|
0.90
|
|
49
|
Functional genetic screens identify genes essential for tumor cell survival in head and neck and lung cancer.
|
Clin Cancer Res
|
2013
|
0.89
|
|
50
|
Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck.
|
BMC Med Genomics
|
2009
|
0.89
|
|
51
|
Differential Proteomics Identifies Protein Biomarkers That Predict Local Relapse of Head and Neck Squamous Cell Carcinomas.
|
Clin Cancer Res
|
2009
|
0.89
|
|
52
|
No evidence for active human papillomavirus (HPV) in fields surrounding HPV-positive oropharyngeal tumors.
|
J Oral Pathol Med
|
2013
|
0.88
|
|
53
|
Discordance of genetic alterations between primary head and neck tumors and corresponding metastases associated with mutational status of the TP53 gene.
|
Genes Chromosomes Cancer
|
2002
|
0.86
|
|
54
|
Treatment response of HPV-positive and HPV-negative head and neck squamous cell carcinoma cell lines.
|
Oral Oncol
|
2013
|
0.86
|
|
55
|
Microarray analysis of bleomycin-exposed lymphoblastoid cells for identifying cancer susceptibility genes.
|
Mol Cancer Res
|
2006
|
0.86
|
|
56
|
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.
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PLoS One
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2013
|
0.85
|
|
57
|
Molecular screening of oral precancer.
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Oral Oncol
|
2013
|
0.84
|
|
58
|
Protein signatures associated with tumor cell dissemination in head and neck cancer.
|
J Proteomics
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2011
|
0.84
|
|
59
|
Loss of heterozygosity at 9p and p53 immunopositivity in surgical margins predict local relapse in head and neck squamous cell carcinoma.
|
Int J Cancer
|
2011
|
0.84
|
|
60
|
Quantitative molecular detection of minimal residual head and neck cancer in lymph node aspirates.
|
Clin Cancer Res
|
2003
|
0.84
|
|
61
|
Intensity-based analysis of dual-color gene expression data as an alternative to ratio-based analysis to enhance reproducibility.
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BMC Genomics
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2010
|
0.84
|
|
62
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Re: Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients.
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J Natl Cancer Inst
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2004
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0.84
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63
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To DNA or not to DNA? That is the question, when it comes to molecular subtyping for the clinic!
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Clin Cancer Res
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2011
|
0.83
|
|
64
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Identification of lethal microRNAs specific for head and neck cancer.
|
Clin Cancer Res
|
2013
|
0.83
|
|
65
|
Comparative evaluation of genetic assays to identify oral pre-cancerous fields.
|
J Oral Pathol Med
|
2008
|
0.82
|
|
66
|
No evidence for FANCF gene silencing in head-and-neck squamous cell carcinomas.
|
Cell Oncol
|
2009
|
0.82
|
|
67
|
Prognostic value of DNA ploidy status in patients with oral leukoplakia.
|
Oral Oncol
|
2011
|
0.81
|
|
68
|
Histopathologic validation of the sentinel node concept in oral and oropharyngeal squamous cell carcinoma.
|
Head Neck
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2005
|
0.81
|
|
69
|
Molecular detection of minimal residual cancer in surgical margins of head and neck cancer patients.
|
Cell Oncol
|
2009
|
0.80
|
|
70
|
Human lymphoblastoid proteome analysis reveals a role for the inhibitor of acetyltransferases complex in DNA double-strand break response.
|
Cancer Res
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2006
|
0.80
|
|
71
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CD98 marks a subpopulation of head and neck squamous cell carcinoma cells with stem cell properties.
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Stem Cell Res
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2013
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0.79
|
|
72
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Molecular diagnosis of minimal residual disease in head and neck cancer patients.
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Cell Oncol (Dordr)
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2012
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0.78
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|
73
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Adenovirus retargeting to surface expressed antigens on oral mucosa.
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J Gene Med
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2010
|
0.78
|
|
74
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Nonmalignant oral keratinocytes from patients with head and neck squamous cell carcinoma show enhanced metabolism of retinoic acid.
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Oncology
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2002
|
0.77
|
|
75
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Generation of precursor cell lines from preneoplastic fields surrounding head and neck cancers.
|
Head Neck
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2012
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0.77
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|
76
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Current potential and limitations of molecular diagnostic methods in head and neck cancer.
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Eur Arch Otorhinolaryngol
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2010
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0.77
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|
77
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Biomarkers predicting malignant progression of laryngeal epithelial precursor lesions: a systematic review.
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Eur Arch Otorhinolaryngol
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2011
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0.76
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78
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tigaR: integrative significance analysis of temporal differential gene expression induced by genomic abnormalities.
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BMC Bioinformatics
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2014
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0.75
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79
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A comprehensive assessment protocol including patient reported outcomes, physical tests, and biological sampling in newly diagnosed patients with head and neck cancer: is it feasible?
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Support Care Cancer
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2014
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0.75
|
|
80
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Correspondence re: M. P. Rosin et al., 3p14 and 9p21 Loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites. Cancer Res., 62: 6447-6450, 2002.
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Cancer Res
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2003
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0.75
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81
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Comparative proteome analysis to explore p53 pathway disruption in head and neck carcinogenesis.
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J Proteomics
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2009
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0.75
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