Published in Acta Pharmacol Sin on February 01, 2010
Wnt pathway activity in breast cancer sub-types and stem-like cells. PLoS One (2013) 1.21
A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes. Clin Cancer Res (2010) 1.07
Skeletal metastasis: treatments, mouse models, and the Wnt signaling. Chin J Cancer (2013) 0.95
Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected]. PLoS One (2013) 0.92
Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP. Mol Cancer (2014) 0.90
Myosin light chain kinase is responsible for high proliferative ability of breast cancer cells via anti-apoptosis involving p38 pathway. Acta Pharmacol Sin (2010) 0.87
Dickkopf-1 is regulated by the mevalonate pathway in breast cancer. Breast Cancer Res (2014) 0.84
sFRP1 inhibits epithelial-mesenchymal transition in A549 human lung adenocarcinoma cell line. Cancer Biother Radiopharm (2013) 0.83
Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells. Endocr Relat Cancer (2014) 0.83
PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulation. J Cell Mol Med (2014) 0.77
The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases. Clin Exp Metastasis (2015) 0.76
The best of both worlds - managing the cancer, saving the bone. Nat Rev Endocrinol (2015) 0.75
The expression of Wnt-inhibitor DKK1 (Dickkopf 1) is determined by intercellular crosstalk and hypoxia in human malignant gliomas. J Cancer Res Clin Oncol (2014) 0.75
The role of Dickkopf family in cancers: from Bench to Bedside. Am J Cancer Res (2017) 0.75
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature (2001) 7.44
LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development (2004) 6.21
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature (2002) 5.61
Control of c-myc regulation in normal and neoplastic cells. Adv Cancer Res (1991) 4.60
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol (2001) 4.38
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell (2005) 3.78
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell (2004) 3.30
Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res (2001) 3.29
The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. Oncogene (2005) 3.01
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene (2006) 2.69
Wnt signaling regulates pancreatic beta cell proliferation. Proc Natl Acad Sci U S A (2007) 2.61
HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J (2003) 2.47
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci U S A (2004) 2.46
Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97. World J Gastroenterol (2001) 2.32
Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res (2005) 2.32
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem (1999) 2.12
NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells. Cancer Res (2008) 2.01
Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation. Breast Cancer Res (2007) 1.93
Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling. Cancer Lett (2008) 1.68
An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res (2004) 1.64
Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol (2004) 1.56
Expression of Dickkopf genes is strongly reduced in malignant melanoma. Oncogene (2006) 1.53
Wnt breakers in colon cancer. Cancer Cell (2004) 1.46
Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells. Gene (2002) 1.34
Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma. Biochem Biophys Res Commun (2004) 1.31
Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation. Eur J Pharmacol (2008) 1.26
Regulation of prostate cell growth and morphogenesis by Dickkopf-3. Oncogene (2006) 1.26
Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53. Oncogene (2000) 1.23
Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells. Transl Res (2007) 1.14
Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer. Eur J Cancer (2005) 1.05
Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2. Cancer Lett (2008) 1.05
Wnt inhibitory factor inhibits lung cancer cell growth. J Thorac Cardiovasc Surg (2007) 1.03
Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells. Acta Pharmacol Sin (2007) 1.03
Dickkopf-1 mediated tumor suppression in human breast carcinoma cells. Breast Cancer Res Treat (2007) 1.01
Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1. J Biol Chem (2007) 1.00
A positive feedback between activated extracellularly regulated kinase and cyclooxygenase/lipoxygenase maintains proliferation and migration of breast cancer cells. Endocrinology (2008) 0.94
[Screening of a sub-clone of human breast cancer cells with high metastasis potential]. Zhonghua Yi Xue Za Zhi (2006) 0.89
Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells. Mol Vis (2006) 0.87
Essential function for ErbB3 in breast cancer proliferation. Breast Cancer Res (2004) 0.87
Synergistic protective effect of picroside II and NGF on PC12 cells against oxidative stress induced by H2O2. Pharmacol Rep (2007) 1.12
Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions. Gut (2011) 1.02
NF-kappaB downregulation may be involved the depression of tumor cell proliferation mediated by human mesenchymal stem cells. Acta Pharmacol Sin (2008) 0.99
Identification of a natural mutant of HBV X protein truncated 27 amino acids at the COOH terminal and its effect on liver cell proliferation. Acta Pharmacol Sin (2008) 0.96
Transformation of human liver L-O2 cells mediated by stable HBx transfection. Acta Pharmacol Sin (2009) 0.95
[Screening of a sub-clone of human breast cancer cells with high metastasis potential]. Zhonghua Yi Xue Za Zhi (2006) 0.89
Promotion of cell proliferation by HBXIP via upregulation of human telomerase reverse transcriptase in human mesenchymal stem cells. Acta Pharmacol Sin (2008) 0.87
Myosin light chain kinase is responsible for high proliferative ability of breast cancer cells via anti-apoptosis involving p38 pathway. Acta Pharmacol Sin (2010) 0.87
Protection of minocycline on early brain injury after subarachnoid hemorrhage in rats. Acta Neurochir Suppl (2011) 0.87
Hepatitis B virus X protein promotes hepatoma cell proliferation via upregulation of MEKK2. Acta Pharmacol Sin (2011) 0.86
A mutant of HBx (HBxDelta127) promotes hepatoma cell growth via sterol regulatory element binding protein 1c involving 5-lipoxygenase. Acta Pharmacol Sin (2010) 0.83
Proteomic alteration of Marc-145 cells and PAMs after infection by porcine reproductive and respiratory syndrome virus. Vet Immunol Immunopathol (2011) 0.83
Factors affecting the long-term renal allograft survival. Chin Med J (Engl) (2011) 0.83
Matrix metalloproteinase 9 inhibition reduces early brain injury in cortex after subarachnoid hemorrhage. Acta Neurochir Suppl (2011) 0.82
Rapamycin instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma. Chin Med J (Engl) (2009) 0.82
A mutant of hepatitis B virus X protein (HBx Delta 127) enhances hepatoma cell migration via osteopontin involving 5-lipoxygenase. Acta Pharmacol Sin (2010) 0.82
[Applying bladder outlet obstruction number to predict bladder outlet obstruction of benign prostatic hyperplasia]. Zhonghua Wai Ke Za Zhi (2008) 0.81
Gene expression profiles of human liver cells mediated by hepatitis B virus X protein. Acta Pharmacol Sin (2009) 0.81
ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun (2013) 0.81
Multidetector row-CT in evaluation of living renal donors. Chin Med J (Engl) (2010) 0.81
[Synthesis of Gal-BSA-SPIO and magnetic resonance imaging of ASG receptors in rabbits bearing liver VX2 tumor and human liver]. Nan Fang Yi Ke Da Xue Xue Bao (2009) 0.80
Down-regulated energy metabolism genes associated with mitochondria oxidative phosphorylation and fatty acid metabolism in viral cardiomyopathy mouse heart. Mol Biol Rep (2010) 0.79
Association of apolipoprotein E polymorphisms with cerebral vasospasm after spontaneous subarachnoid hemorrhage. Acta Neurochir Suppl (2011) 0.78
Video-urodynamics study on female patients with bladder neck obstruction. Chin Med J (Engl) (2012) 0.78
Rituximab induction therapy in highly sensitized kidney transplant recipients. Chin Med J (Engl) (2011) 0.78
[Association of the changes of central serotonin and peripheral blood free amino acids with postoperative fatigue after abdominal surgery]. Zhonghua Wei Chang Wai Ke Za Zhi (2011) 0.78
A novel positive feedback loop involving FASN/p-ERK1/2/5-LOX/LTB4/FASN sustains high growth of breast cancer cells. Acta Pharmacol Sin (2011) 0.77
[Effect of drainage of the cerebrospinal fluid at the acute period of aneurysmal subarachnoid hemorrhage on the formation of hydrocephalus]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue (2007) 0.77
Protein A immunoadsorption combined with rituximab in highly sensitized kidney transplant recipients. Chin Med J (Engl) (2009) 0.77
Relationship between MDR1 polymorphism and blood concentration of cyclosporine A. Chin Med J (Engl) (2005) 0.77
[Relationship between MDR1 gene polymorphism and blood concentration of tacrolimus in renal transplant patients]. Zhonghua Yi Xue Za Zhi (2005) 0.76
A retrospective comparison of the efficacy and safety in kidney transplant recipients with basiliximab and anti-thymocyte globulin. Chin Med J (Engl) (2012) 0.76
[Influence of different blood purification treatment on the serum leptin and neuropeptide Y levels in patients with chronic renal failure]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2010) 0.76
[Progress and investigation of neuronal plasticity interfered by Borna disease virus infection]. Wei Sheng Wu Xue Bao (2006) 0.75
[Rapid Synthesis of Metal Organic Framework and Its Adsorption Properties on Anonic Dyes]. Huan Jing Ke Xue (2016) 0.75
Electron paramagnetic resonance in monitoring of nitric oxide production after kidney transplantation in rats. Chin Med J (Engl) (2004) 0.75
[Efficacy of E-max porcelain laminate veneer on esthetic restoration for anterior teeth over 2 years]. Shanghai Kou Qiang Yi Xue (2013) 0.75
[Construction of the plant expression vectors containing the multiepitope gene of Toxoplasma gondii]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2003) 0.75
Nanodissection of single- and double-stranded DNA by atomic force microscopy. J Nanosci Nanotechnol (2005) 0.75
[Identification of lower urinary tract voiding dysfunction in females by using video-urodynamic study]. Zhonghua Wai Ke Za Zhi (2012) 0.75
[Study of spectrum drifting of primary colors and its impact on color rendering properties]. Guang Pu Xue Yu Guang Pu Fen Xi (2012) 0.75
Diagnosis of bladder outlet obstruction in men using a near-infrared spectroscopy instrument as the noninvasive monitor for bladder function. Urology (2013) 0.75
[An epidemiological study and analysis of strategy of prevention and treatment of 3134 seriously ill patient in intensive care unit]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue (2012) 0.75
[Sonographic features of lymphoma in the abdominal lymph nodes]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2013) 0.75
[Diagnosis and management of transplant renal artery stenosis caused by early stage acute allograft rejection]. Zhonghua Yi Xue Za Zhi (2008) 0.75
Study of PSA, PSMA and hK2 mRNA in peripheral blood of prostate cancer patients and its clinical implications. Beijing Da Xue Xue Bao (2004) 0.75
Should simultaneous ureteral reimplantation be performed during sigmoid bladder augmentation to reduce vesicoureteral reflux in neurogenic bladder cases? Int Urol Nephrol (2015) 0.75
[Clinical character of renal transplant recipients with bilateral native upper urinary transitional cell carcinoma]. Zhonghua Yi Xue Za Zhi (2009) 0.75
[Diagnostic value and clinical application of inner ear imaging after an intratympanic injection of gadolinium for Meniere's disease]. Zhonghua Yi Xue Za Zhi (2011) 0.75
[Effects of drynaria total flavonoid on osteogenic differentiation of bone marrow mesenchymal stem cells at different glucose concentrations: experiment with rats]. Zhonghua Yi Xue Za Zhi (2010) 0.75
[Effect of TIEG-siRNA on Smad2, p-smad2 and collagen IV in diabetic nephropathy]. Zhonghua Yi Xue Za Zhi (2010) 0.75
[Measurement of Nitrogen Content in Lettuce Canopy Using Spectroscopy Combined with BiPLS-GA-SPA and ELM]. Guang Pu Xue Yu Guang Pu Fen Xi (2016) 0.75
[Application of minimally invasive, decompression bone graft implantation combined with metal trabecular bone reconstruction system for early stage osteonecrosis of femoral head]. Zhongguo Gu Shang (2015) 0.75
Changes in biochemical parameters on the first day after kidney transplantation: risk factors for nosocomial infection? Chin Med J (Engl) (2010) 0.75
[Epirubicin combined with DDP and 5-Fu for treatment of advanced gastric cancer]. Zhonghua Zhong Liu Za Zhi (2009) 0.75
Comparison of catheter ablation and surgical ablation in patients with long-standing persistent atrial fibrillation and rheumatic heart disease: a four-year follow-up study. Int J Cardiol (2013) 0.75
[Retrospective study on regimens of capecitabine-based chemotherapy in the treatment for advanced gastric cancer]. Zhonghua Zhong Liu Za Zhi (2009) 0.75
[Effects of reduced glutathione on contents of hydroxyproline and oxidation stress reaction in kidney of unilateral ureteral obstruction in rat]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue (2007) 0.75
[Cloning and sequence analysis of tomato fruit-specific E8 promoter from Lycopersicon esculentum (Zhongshu No.5)]. Di Yi Jun Yi Da Xue Xue Bao (2003) 0.75
[A Study of the Relationship Among Genetic Distances, NIR Spectra Distances, and NIR-Based Identification Model Performance of the Seeds of Maize Iinbred Lines]. Guang Pu Xue Yu Guang Pu Fen Xi (2015) 0.75
Effect of Wenhua Juanbi recipe on proliferation and apoptosis of synoviocytes in rats with collagen-inducing arthritis. Chin J Integr Med (2011) 0.75
Controversy of the prostate-specific antigen test era: should prostate cancer be detected and treated in all patients? Chin Med J (Engl) (2013) 0.75
[Early diagnosis and treatment of invasive pulmonary aspergillosis following kidney transplantation]. Zhonghua Yi Xue Za Zhi (2010) 0.75
[Length and volume of intravesical prostatic protrusion closely correlated with bladder outflow obstruction in BPH patients]. Zhonghua Nan Ke Xue (2007) 0.75
[Fuzzing pattern recognition study on Raman spectrum of tumor peripheral tissue]. Guang Pu Xue Yu Guang Pu Fen Xi (2006) 0.75
[Experimental study of tissue engineered bone loaded with osteointergrated dental implants]. Zhonghua Kou Qiang Yi Xue Za Zhi (2005) 0.75
[Expression and role of vascular endothelial growth inhibitor in sporadic clear cell renal cell carcinoma]. Zhonghua Yi Xue Za Zhi (2013) 0.75
Cognitive inhibition and shifting in Asperger's syndrome. Psychopathology (2012) 0.75