Published in Chem Res Toxicol on March 15, 2010
Improving the human hazard characterization of chemicals: a Tox21 update. Environ Health Perspect (2013) 2.95
Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environ Health Perspect (2010) 2.06
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity. Environ Sci Technol (2010) 1.54
Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice. Drug Metab Dispos (2012) 1.43
Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data. Toxicol Sci (2012) 1.40
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor. Toxicol Sci (2015) 1.21
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays. Chem Res Toxicol (2013) 1.13
Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model. Toxicol Sci (2012) 1.12
Genetic toxicology in the 21st century: reflections and future directions. Environ Mol Mutagen (2011) 1.12
Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework. Toxicol Sci (2013) 1.10
Addressing human variability in next-generation human health risk assessments of environmental chemicals. Environ Health Perspect (2012) 1.00
The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century. Environ Health Perspect (2010) 1.00
Computational toxicology: realizing the promise of the toxicity testing in the 21st century. Environ Health Perspect (2010) 0.97
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen. PLoS One (2012) 0.91
Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. PLoS One (2011) 0.90
A computational model predicting disruption of blood vessel development. PLoS Comput Biol (2013) 0.89
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project. Environ Health Perspect (2016) 0.87
Mechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalate. Mutat Res (2011) 0.87
Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis? Carcinogenesis (2015) 0.85
Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. Toxicol Sci (2015) 0.84
On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens. Environ Health Perspect (2016) 0.84
Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ. Toxicol Appl Pharmacol (2012) 0.82
Families of nuclear receptors in vertebrate models: characteristic and comparative toxicological perspective. Sci Rep (2015) 0.79
Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish. Toxicol Sci (2014) 0.78
Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions. Carcinogenesis (2015) 0.77
In vitro bioassays to evaluate complex chemical mixtures in recycled water. Water Res (2015) 0.76
Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis. Toxicol Sci (2016) 0.76
Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens". Environ Health Perspect (2017) 0.75
Development and Validation of a Computational Model for Androgen Receptor Activity. Chem Res Toxicol (2016) 0.75
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet (2004) 5.87
The ToxCast program for prioritizing toxicity testing of environmental chemicals. Toxicol Sci (2006) 4.85
In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project. Environ Health Perspect (2010) 3.84
Improving the human hazard characterization of chemicals: a Tox21 update. Environ Health Perspect (2013) 2.95
The toxicity data landscape for environmental chemicals. Environ Health Perspect (2008) 2.68
Machine learning for detecting gene-gene interactions: a review. Appl Bioinformatics (2006) 2.56
Spermatozoal RNA profiles of normal fertile men. Lancet (2002) 2.46
Uncertainties for endocrine disrupters: our view on progress. Toxicol Sci (2003) 2.36
Toward using stable spermatozoal RNAs for prognostic assessment of male factor fertility. Fertil Steril (2005) 2.16
Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environ Health Perspect (2010) 2.06
Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice. Mol Cell Biol (2004) 2.05
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicol Sci (2011) 2.03
Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs. Hum Mol Genet (2007) 1.62
A comparison of analytical methods for genetic association studies. Genet Epidemiol (2008) 1.61
Allelic dropout in long QT syndrome genetic testing: a possible mechanism underlying false-negative results. Heart Rhythm (2006) 1.61
Combinatorial pharmacogenetics. Nat Rev Drug Discov (2005) 1.58
Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. Environ Health Perspect (2011) 1.57
Informing selection of nanomaterial concentrations for ToxCast in vitro testing based on occupational exposure potential. Environ Health Perspect (2011) 1.57
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity. Environ Sci Technol (2010) 1.54
Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database. Environ Health Perspect (2008) 1.51
Multidimensional in vivo hazard assessment using zebrafish. Toxicol Sci (2013) 1.41
Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment. Chem Res Toxicol (2011) 1.38
Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. Toxicol Sci (2009) 1.38
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. Toxicology (2011) 1.36
Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicol Sci (2010) 1.30
Cytokine expression patterns associated with systemic adverse events following smallpox immunization. J Infect Dis (2006) 1.29
Novel methods for detecting epistasis in pharmacogenomics studies. Pharmacogenomics (2007) 1.27
Systems toxicology: from basic research to risk assessment. Chem Res Toxicol (2014) 1.23
Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB. Reprod Toxicol (2009) 1.22
The Tox21 robotic platform for the assessment of environmental chemicals--from vision to reality. Drug Discov Today (2013) 1.21
Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors. Nat Methods (2008) 1.18
An essential role of NF-kappaB in the "tumor-like" phenotype of arthritic synoviocytes. Proc Natl Acad Sci U S A (2006) 1.18
Effects of storage, RNA extraction, genechip type, and donor sex on gene expression profiling of human whole blood. Clin Chem (2007) 1.17
Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. Int J Mol Sci (2012) 1.16
Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist. Proc Natl Acad Sci U S A (2013) 1.16
Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals. Environ Health Perspect (2012) 1.16
Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data. Toxicol Sci (2011) 1.16
Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation. Mol Endocrinol (2003) 1.16
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays. Chem Res Toxicol (2013) 1.13