Published in Cancer Res on February 09, 2010
Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One (2012) 1.43
CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma. Pigment Cell Melanoma Res (2011) 1.09
The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis. Am J Pathol (2012) 0.98
Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanoma. Cancer Res (2012) 0.93
Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathways. Evid Based Complement Alternat Med (2012) 0.92
Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis. PLoS One (2012) 0.91
mda-9/Syntenin protein positively regulates the activation of Akt protein by facilitating integrin-linked kinase adaptor function during adhesion to type I collagen. J Biol Chem (2011) 0.91
Targeting tumor invasion: the roles of MDA-9/Syntenin. Expert Opin Ther Targets (2014) 0.89
MDA-9/syntenin is a key regulator of glioma pathogenesis. Neuro Oncol (2013) 0.88
Syndecan binding protein (SDCBP) is overexpressed in estrogen receptor negative breast cancers, and is a potential promoter for tumor proliferation. PLoS One (2013) 0.87
Elevated expression of syntenin in breast cancer is correlated with lymph node metastasis and poor patient survival. Breast Cancer Res (2013) 0.86
Cell susceptibility to baculovirus transduction and echovirus infection is modified by protein kinase C phosphorylation and vimentin organization. J Virol (2013) 0.84
Silencing profilin-1 inhibits gastric cancer progression via integrin β1/focal adhesion kinase pathway modulation. World J Gastroenterol (2015) 0.84
Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton. J Biol Chem (2014) 0.83
Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation. Proc Natl Acad Sci U S A (2014) 0.82
Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization. Oncogene (2015) 0.82
D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways. Int J Mol Sci (2013) 0.80
PTTG promotes invasion in human breast cancer cell line by upregulating EMMPRIN via FAK/Akt/mTOR signaling. Am J Cancer Res (2016) 0.78
Syntenin is expressed in human follicular dendritic cells and involved in the activation of focal adhesion kinase. Immune Netw (2013) 0.78
Examination of Epigenetic and other Molecular Factors Associated with mda-9/Syntenin Dysregulation in Cancer Through Integrated Analyses of Public Genomic Datasets. Adv Cancer Res (2015) 0.76
Constrained inference of protein interaction networks for invadopodium formation in cancer. IET Syst Biol (2016) 0.75
Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis. Oncotarget (2016) 0.75
MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial-mesenchymal transition in breast cancer. Oncotarget (2016) 0.75
Syntenin is expressed in human gliomas and may correlate with tumor migration. Arch Med Sci (2015) 0.75
Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. Biochem Pharmacol (2006) 1.91
Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system. Cancer Res (2003) 1.45
Antidiabetes and Anti-obesity Activity of Lagerstroemia speciosa. Evid Based Complement Alternat Med (2007) 1.31
Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines. Oncogene (2002) 1.31
Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. Carcinogenesis (2008) 1.27
Antiinflammatory constituents of Celastrus orbiculatus inhibit the NF-kappaB activation and NO production. J Nat Prod (2002) 1.18
Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors. Bioorg Med Chem Lett (2007) 1.12
(Aryloxyacetylamino)benzoic acid analogues: A new class of hypoxia-inducible factor-1 inhibitors. J Med Chem (2007) 1.10
The interferon-inducible 9-27 gene modulates the susceptibility to natural killer cells and the invasiveness of gastric cancer cells. Cancer Lett (2005) 1.07
Adiponectin is a negative regulator of NK cell cytotoxicity. J Immunol (2006) 1.06
An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination. J Biol Chem (2010) 1.03
Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem (2002) 1.01
Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-D-glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway. Biochem Biophys Res Commun (2005) 0.98
Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera. J Pharmacol Exp Ther (2005) 0.95
Rational biosynthetic engineering for optimization of geldanamycin analogues. Chembiochem (2009) 0.94
Inactivation of the carbamoyltransferase gene refines post-polyketide synthase modification steps in the biosynthesis of the antitumor agent geldanamycin. J Am Chem Soc (2004) 0.93
Macrophage inhibitory cytokine-1 transactivates ErbB family receptors via the activation of Src in SK-BR-3 human breast cancer cells. BMB Rep (2010) 0.92
Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species. J Nat Prod (2009) 0.92
Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis. PLoS One (2012) 0.91
Phenanthroquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells. J Nat Prod (2006) 0.91
mda-9/Syntenin protein positively regulates the activation of Akt protein by facilitating integrin-linked kinase adaptor function during adhesion to type I collagen. J Biol Chem (2011) 0.91
Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation. Eur J Pharmacol (2011) 0.91
The first total synthesis of moracin O and moracin P, and establishment of the absolute configuration of moracin O. Chem Commun (Camb) (2009) 0.91
Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod (2008) 0.89
Cucurbitacin B suppresses the transactivation activity of RelA/p65. J Cell Biochem (2011) 0.89
The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages. Int Immunopharmacol (2009) 0.88
A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway. Biochem Biophys Res Commun (2009) 0.88
Angiogenic activity of sesamin through the activation of multiple signal pathways. Biochem Biophys Res Commun (2009) 0.87
Interleukin-32β stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway. Cell Oncol (Dordr) (2013) 0.87
Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms. Arch Pharm Res (2006) 0.86
Polychlorinated compounds with PPAR-gamma agonistic effect from the medicinal fungus Phellinus ribis. Bioorg Med Chem Lett (2008) 0.86
A novel dihydroxanthenone, AGI-B4 with inhibition of VEGF-induced endothelial cell growth. J Antibiot (Tokyo) (2002) 0.86
Syringaresinol causes vasorelaxation by elevating nitric oxide production through the phosphorylation and dimerization of endothelial nitric oxide synthase. Exp Mol Med (2012) 0.86
Mutasynthesis of geldanamycin by the disruption of a gene producing starter unit: generation of structural diversity at the benzoquinone ring. Chembiochem (2007) 0.86
Bisacurone inhibits adhesion of inflammatory monocytes or cancer cells to endothelial cells through down-regulation of VCAM-1 expression. Int Immunopharmacol (2008) 0.85
Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety. Chembiochem (2006) 0.85
Lignans from Saururus chinensis inhibiting the transcription factor NF-kappaB. Phytochemistry (2003) 0.85
Caesaldecan, a cassane diterpenoid from the leaves of Caesalpinia decapetala. Chem Pharm Bull (Tokyo) (2005) 0.85
Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1. J Nat Prod (2007) 0.85
Diarylheptanoids from Alnus hirsuta inhibit the NF-kB activation and NO and TNF-alpha production. Biol Pharm Bull (2007) 0.84
The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression. Oncol Rep (2010) 0.83
Furanoligularenone, an eremophilane from Ligularia fischeri, inhibits the LPS-induced production of nitric oxide and prostaglandin E2 in macrophage RAW264.7 cells. Planta Med (2002) 0.83
A diterpenoid acanthoic acid from Acanthopanax koreanum protects against D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice. Biol Pharm Bull (2008) 0.83
Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-κB pathway. Biochem Biophys Res Commun (2010) 0.82
Sauchinone, a lignan from Saururus chinensis, suppresses iNOS expression through the inhibition of transactivation activity of RelA of NF-kappaB. Planta Med (2003) 0.82
A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation. Eur J Pharmacol (2008) 0.82
Inhibitors of the LPS-induced NF-kappaB activation from Artemisia sylvatica. Phytochemistry (2004) 0.82
Hepatoprotective effects of Sedum sarmentosum on D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure. J Pharmacol Sci (2010) 0.82
Malabaricone C suppresses lipopolysaccharide-induced inflammatory responses via inhibiting ROS-mediated Akt/IKK/NF-κB signaling in murine macrophages. Int Immunopharmacol (2012) 0.81
4′,6-dihydroxy-4-methoxyisoaurone inhibits the HIF-1α pathway through inhibition of Akt/mTOR/p70S6K/4E-BP1 phosphorylation. J Pharmacol Sci (2014) 0.81
Cytotoxic prenylated flavonoids from Morus alba. Fitoterapia (2010) 0.81
Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells. Cancer Lett (2010) 0.81
Suppression of distant pulmonary metastasis of MDA-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TIMP-2 gene transfer. J Gene Med (2005) 0.81
Influenza virus assays based on virus-inducible reporter cell lines. Influenza Other Respir Viruses (2009) 0.81
Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs. J Antibiot (Tokyo) (2002) 0.80
Hypoxia-inducible factor-1 and nuclear factor-kappaB inhibitory meroterpene analogues of bakuchiol, a constituent of the seeds of Psoralea corylifolia. Bioorg Med Chem Lett (2008) 0.80
Kaurane-type diterpene glycoside from the stem bark of Acanthopanax trifoliatus. Planta Med (2004) 0.80
New sesquiterpene dimers from Inula britannica inhibit NF-kappaB activation and NO and TNF-alpha production in LPS-stimulated RAW264.7 cells. Planta Med (2006) 0.80
Two new furanoditerpenes from Saururus chinenesis and their effects on the activation of peroxisome proliferator-activated receptor gamma. J Nat Prod (2002) 0.79
In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents. Biol Pharm Bull (2007) 0.79
Lupane-triterpene carboxylic acids from the leaves of Acanthopanax trifoliatus. Chem Pharm Bull (Tokyo) (2003) 0.79
Acanthoic acid from Acanthopanax koreanum protects against liver injury induced by tert-butyl hydroperoxide or carbon tetrachloride in vitro and in vivo. Planta Med (2004) 0.79
A peroxisome proliferator-activated receptor-gamma agonist and other constituents from Chromolaena odorata. Planta Med (2009) 0.79
New Guaiane Sesquiterpenes from the Fruits of Torilis japonica. Chem Pharm Bull (Tokyo) (2008) 0.78
Effects of licarin E on expression of matrix metalloproteinase-1 and type-1 procollagen in UVB-irradiated human skin fibroblasts. Phytother Res (2011) 0.78
An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB. J Nat Prod (2010) 0.78
Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res (2007) 0.78
Macelignan inhibits melanosome transfer mediated by protease-activated receptor-2 in keratinocytes. Biol Pharm Bull (2011) 0.78
Lupane-triterpenes from the leaves of Brassaiopsis glomerulata. Arch Pharm Res (2003) 0.78
Eupatolide inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6. Eur J Pharmacol (2010) 0.78
The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells. Cancer Biol Ther (2011) 0.78
Four ent-kaurane-type diterpenoids from Croton tonkinensis Gagnep. Chem Pharm Bull (Tokyo) (2004) 0.78
Syntenin is expressed in human follicular dendritic cells and involved in the activation of focal adhesion kinase. Immune Netw (2013) 0.78
Effect of 5-O-Methylhirsutanonol on nuclear factor-kappaB-dependent production of NO and expression of iNOS in lipopolysaccharide-induced RAW264.7 cells. J Agric Food Chem (2007) 0.78
Assessment of the diet quality of middle-aged and older adult Korean Americans living in Chicago. J Am Diet Assoc (2002) 0.78
Water-soluble polysaccharide from Eleutherococcus senticosus stems attenuates fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice. Basic Clin Pharmacol Toxicol (2004) 0.78
Eupatolide inhibits PDGF-induced proliferation and migration of aortic smooth muscle cells through ROS-dependent heme oxygenase-1 induction. Phytother Res (2013) 0.77
Triterpenoids and diarylheptanoids from Alnus hirsuta inhibit HIF-1 in AGS cells. Arch Pharm Res (2007) 0.77
Quinolone alkaloids with inhibitory activity against nuclear factor of activated T cells from the fruits of Evodia rutaecarpa. Biol Pharm Bull (2004) 0.77
Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans. Phytother Res (2013) 0.77
6-Alkylsalicylic acid analogues inhibit in vitro ATPase activity of heat shock protein 90. Arch Pharm Res (2010) 0.77
Two new phenylpropanoid glycosides from the stem bark of Acanthopanax trifoliatus. Arch Pharm Res (2003) 0.77
Phenolic constituents with inhibitory activity against NFAT transcription from Desmos chinensis. Arch Pharm Res (2005) 0.77
Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo. Arch Pharm Res (2008) 0.77