Published in Anal Chem on March 01, 2010
Lipidomics: coming to grips with lipid diversity. Nat Rev Mol Cell Biol (2010) 2.72
Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. Anal Chem (2014) 1.45
Experimental evaluation and optimization of structures for lossless ion manipulations for ion mobility spectrometry with time-of-flight mass spectrometry. Anal Chem (2014) 1.24
Mobility-resolved ion selection in uniform drift field ion mobility spectrometry/mass spectrometry: dynamic switching in structures for lossless ion manipulations. Anal Chem (2014) 1.22
Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure. PLoS One (2011) 1.16
Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury. J Neurochem (2010) 1.14
Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry. Biochim Biophys Acta (2011) 1.13
Separation and classification of lipids using differential ion mobility spectrometry. J Am Soc Mass Spectrom (2011) 1.07
Ion mobility-mass spectrometry: time-dispersive instrumentation. Anal Chem (2015) 1.04
Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification. Anal Chem (2014) 1.02
Resolving structural isomers of monosaccharide methyl glycosides using drift tube and traveling wave ion mobility mass spectrometry. Anal Chem (2012) 1.01
Ion mobility derived collision cross sections to support metabolomics applications. Anal Chem (2014) 1.00
Imaging mass spectrometry in transmission geometry. Rapid Commun Mass Spectrom (2011) 0.99
Carbohydrate structure characterization by tandem ion mobility mass spectrometry (IMMS)2. Anal Chem (2013) 0.95
Amphitrite: A program for processing travelling wave ion mobility mass spectrometry data. Int J Mass Spectrom (2013) 0.90
Size, weight and position: ion mobility spectrometry and imaging MS combined. Anal Bioanal Chem (2011) 0.85
Huntingtin N-Terminal Monomeric and Multimeric Structures Destabilized by Covalent Modification of Heteroatomic Residues. Biochemistry (2015) 0.81
Laserspray ionization imaging of multiply charged ions using a commercial vacuum MALDI ion source. Anal Chem (2012) 0.81
Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts. Anal Chem (2016) 0.79
Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry. Anal Chem (2016) 0.79
Structural separations by ion mobility-MS for glycomics and glycoproteomics. Methods Mol Biol (2013) 0.78
Electrospray Quadrupole Travelling Wave Ion Mobility Time-of-Flight Mass Spectrometry for the Detection of Plasma Metabolome Changes Caused by Xanthohumol in Obese Zucker (fa/fa) Rats. Metabolites (2013) 0.76
Assessment of altered lipid homeostasis by HILIC-ion mobility-mass spectrometry-based lipidomics. J Lipid Res (2017) 0.75
Polymers for Traveling Wave Ion Mobility Spectrometry Calibration. J Am Soc Mass Spectrom (2017) 0.75
Collisional Cross-Sections with T-Wave Ion Mobility Spectrometry without Experimental Calibration. J Am Soc Mass Spectrom (2017) 0.75
Large-Scale Structural Characterization of Drug and Drug-Like Compounds by High-Throughput Ion Mobility-Mass Spectrometry. Anal Chem (2017) 0.75
Ion mobility-mass spectrometry analysis of large protein complexes. Nat Protoc (2008) 3.51
Evidence for macromolecular protein rings in the absence of bulk water. Science (2005) 3.26
Ion mobility-mass spectrometry. J Mass Spectrom (2008) 2.91
Automated acoustic matrix deposition for MALDI sample preparation. Anal Chem (2006) 2.83
Applications of a travelling wave-based radio-frequency-only stacked ring ion guide. Rapid Commun Mass Spectrom (2004) 2.80
Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry. J Mass Spectrom (2007) 2.20
Fundamentals of traveling wave ion mobility spectrometry. Anal Chem (2008) 2.02
In situ structural characterization of phosphatidylcholines in brain tissue using MALDI-MS/MS. J Am Soc Mass Spectrom (2005) 1.84
MALDI-ion mobility-TOFMS imaging of lipids in rat brain tissue. J Mass Spectrom (2007) 1.70
Profiling and imaging of tissues by imaging ion mobility-mass spectrometry. J Mass Spectrom (2007) 1.55
Biomolecular structural separations by ion mobility-mass spectrometry. Anal Bioanal Chem (2008) 1.54
Characterizing ion mobility-mass spectrometry conformation space for the analysis of complex biological samples. Anal Bioanal Chem (2009) 1.52
A database of 660 peptide ion cross sections: use of intrinsic size parameters for bona fide predictions of cross sections. J Am Soc Mass Spectrom (1999) 1.49
Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexes. Angew Chem Int Ed Engl (2007) 1.47
Characterization of phosphorylated peptides using traveling wave-based and drift cell ion mobility mass spectrometry. Anal Chem (2009) 1.29
Determination of stoichiometry and conformational changes in the first step of the P22 tail assembly. J Mol Biol (2008) 1.27
Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements. Rapid Commun Mass Spectrom (2008) 1.18
A study of phospholipids by ion mobility TOFMS. J Am Soc Mass Spectrom (2008) 1.18
A collision cross-section database of singly-charged peptide ions. J Am Soc Mass Spectrom (2007) 1.16
Intermolecular interactions in biomolecular systems examined by mass spectrometry. Annu Rev Phys Chem (2007) 1.11
Developing liquid chromatography ion mobility mass spectometry techniques. Expert Rev Proteomics (2005) 1.08
The influence and utility of varying field strength for the separation of tryptic peptides by ion mobility-mass spectrometry. J Am Soc Mass Spectrom (2005) 1.07
Distinguishing between phosphorylated and nonphosphorylated peptides with ion mobility-mass spectrometry. J Proteome Res (2003) 1.06
Conformations of Gly(n)H+ and Ala(n)H+ peptides in the gas phase. Biophys J (1999) 1.05
Observation of conserved solution-phase secondary structure in gas-phase tryptic peptides. J Am Chem Soc (2002) 1.01
Resolution equations for high-field ion mobility. J Am Soc Mass Spectrom (2004) 0.98
Probing hemoglobin structure by means of traveling-wave ion mobility mass spectrometry. J Am Soc Mass Spectrom (2008) 0.96
Enhanced carbohydrate structural selectivity in ion mobility-mass spectrometry analyses by boronic acid derivatization. Chem Commun (Camb) (2008) 0.96
The structure of gas-phase bradykinin fragment 1-5 (RPPGF) ions: an ion mobility spectrometry and H/D exchange ion-molecule reaction chemistry study. J Am Soc Mass Spectrom (2005) 0.96
Coupling desorption electrospray ionisation and neutral desorption/extractive electrospray ionisation with a travelling-wave based ion mobility mass spectrometer for the analysis of drugs. Rapid Commun Mass Spectrom (2008) 0.93
Development of a high-throughput IMS-IMS-MS approach for analyzing mixtures of biomolecules. J Proteomics (2008) 0.92
Metal chelation and inhibition of bacterial growth in tissue abscesses. Science (2008) 4.55
MALDI imaging mass spectrometry: molecular snapshots of biochemical systems. Nat Methods (2007) 4.20
Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet (2003) 4.01
Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Anal Chem (2006) 3.03
Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation. J Mass Spectrom (2003) 2.84
Automated acoustic matrix deposition for MALDI sample preparation. Anal Chem (2006) 2.83
Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression. Clin Cancer Res (2004) 2.41
Molecular imaging of proteins in tissues by mass spectrometry. Proc Natl Acad Sci U S A (2008) 2.38
New developments in profiling and imaging of proteins from tissue sections by MALDI mass spectrometry. J Proteome Res (2006) 2.33
Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. Development (2005) 2.31
Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction. Nat Methods (2008) 2.24
Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry. J Mass Spectrom (2007) 2.20
Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry. J Mass Spectrom (2003) 2.15
MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue. Anal Chem (2008) 2.09
Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res (2005) 2.06
A novel histology-directed strategy for MALDI-MS tissue profiling that improves throughput and cellular specificity in human breast cancer. Mol Cell Proteomics (2006) 2.03
Enhancement of protein sensitivity for MALDI imaging mass spectrometry after chemical treatment of tissue sections. J Am Soc Mass Spectrom (2008) 1.96
High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry. Proteomics (2008) 1.91
Integrating histology and imaging mass spectrometry. Anal Chem (2004) 1.86
Solvent-free matrix dry-coating for MALDI imaging of phospholipids. J Am Soc Mass Spectrom (2008) 1.86
Proteome analysis of human colon cancer by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics (2004) 1.82
Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research. Chem Rev (2013) 1.80
Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am J Pathol (2004) 1.76
Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis. Int J Mass Spectrom (2007) 1.73
Molecular imaging by mass spectrometry--looking beyond classical histology. Nat Rev Cancer (2010) 1.72
MALDI-MS-based imaging of small molecules and proteins in tissues. Curr Opin Chem Biol (2006) 1.66
Tissue profiling by mass spectrometry: a review of methodology and applications. Mol Cell Proteomics (2005) 1.64
Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry. J Am Soc Mass Spectrom (2005) 1.62
Imaging of intact tissue sections: moving beyond the microscope. J Biol Chem (2011) 1.60
Mass spectrometric profiling of intact biological tissue by using desorption electrospray ionization. Angew Chem Int Ed Engl (2005) 1.59
The pros and cons of peptide-centric proteomics. Nat Biotechnol (2010) 1.58
Monitoring the inflammatory response to infection through the integration of MALDI IMS and MRI. Cell Host Microbe (2012) 1.58
Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Nat Methods (2007) 1.58
Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation. J Lipid Res (2009) 1.58
Direct imaging of single cells and tissue at sub-cellular spatial resolution using transmission geometry MALDI MS. J Mass Spectrom (2012) 1.57
Profiling and imaging of tissues by imaging ion mobility-mass spectrometry. J Mass Spectrom (2007) 1.55
Biomolecular structural separations by ion mobility-mass spectrometry. Anal Bioanal Chem (2008) 1.54
Imaging mass spectrometry: principles and potentials. Toxicol Pathol (2005) 1.54
Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer Res (2004) 1.53
Characterizing ion mobility-mass spectrometry conformation space for the analysis of complex biological samples. Anal Bioanal Chem (2009) 1.52
Matrix sublimation/recrystallization for imaging proteins by mass spectrometry at high spatial resolution. Anal Chem (2011) 1.52
Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. PLoS Pathog (2012) 1.47
Imaging mass spectrometry: a new tool to investigate the spatial organization of peptides and proteins in mammalian tissue sections. Curr Opin Chem Biol (2002) 1.47
Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs. Am J Physiol Lung Cell Mol Physiol (2008) 1.46
Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. Anal Chem (2014) 1.45
Proteomic patterns and prediction of glomerulosclerosis and its mechanisms. J Am Soc Nephrol (2005) 1.44
Assessing protein patterns in disease using imaging mass spectrometry. J Proteome Res (2004) 1.44
Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation. Clin Cancer Res (2010) 1.43
Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry. Electrophoresis (2002) 1.42
Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer. J Thorac Oncol (2007) 1.40
Instrument design and characterization for high resolution MALDI-MS imaging of tissue sections. J Mass Spectrom (2007) 1.34
Proteomic patterns of preinvasive bronchial lesions. Am J Respir Crit Care Med (2005) 1.32
3D imaging by mass spectrometry: a new frontier. Anal Chem (2012) 1.31
Peak capacity of ion mobility mass spectrometry: the utility of varying drift gas polarizability for the separation of tryptic peptides. J Mass Spectrom (2004) 1.30
MALDI imaging of lipid biochemistry in tissues by mass spectrometry. Chem Rev (2011) 1.29
Proteomic analysis of formalin-fixed paraffin-embedded tissue by MALDI imaging mass spectrometry. Nat Protoc (2011) 1.28
Imaging mass spectrometry reveals unique protein profiles during embryo implantation. Endocrinology (2008) 1.28
Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma. J Proteome Res (2010) 1.27
Direct analysis of laser capture microdissected cells by MALDI mass spectrometry. J Am Soc Mass Spectrom (2002) 1.24
Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. IEEE Trans Biomed Eng (2013) 1.21
Biomarker discovery by imaging mass spectrometry: transthyretin is a biomarker for gentamicin-induced nephrotoxicity in rat. Mol Cell Proteomics (2006) 1.19
MALDI imaging mass spectrometry of integral membrane proteins from ocular lens and retinal tissue. J Proteome Res (2009) 1.18
High-speed MALDI-TOF imaging mass spectrometry: rapid ion image acquisition and considerations for next generation instrumentation. J Am Soc Mass Spectrom (2011) 1.18
MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infect Immun (2013) 1.17
Decreased striatal levels of PEP-19 following MPTP lesion in the mouse. J Proteome Res (2006) 1.17
Imaging mass spectrometry: a new tool for pathology in a molecular age. Proteomics Clin Appl (2013) 1.17
Profiling and imaging proteins in the mouse epididymis by imaging mass spectrometry. Proteomics (2003) 1.17
Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry. J Proteome Res (2004) 1.17
A collision cross-section database of singly-charged peptide ions. J Am Soc Mass Spectrom (2007) 1.16
MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives. Trends Biotechnol (2011) 1.15
Alterations in the diabetic myocardial proteome coupled with increased myocardial oxidative stress underlies diabetic cardiomyopathy. J Mol Cell Cardiol (2007) 1.15
Characterization of glycosylation sites of the epidermal growth factor receptor. Biochemistry (2003) 1.14
MALDI mass spectrometry for direct tissue analysis: a new tool for biomarker discovery. J Proteome Res (2005) 1.14
From whole-body sections down to cellular level, multiscale imaging of phospholipids by MALDI mass spectrometry. Mol Cell Proteomics (2010) 1.14
Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients. Cancer Epidemiol Biomarkers Prev (2010) 1.13
Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry. Biochim Biophys Acta (2011) 1.13
Direct tissue analysis by matrix-assisted laser desorption ionization mass spectrometry: application to kidney biology. Semin Nephrol (2007) 1.13
Variations in the expressed antimicrobial peptide repertoire of northern leopard frog (Rana pipiens) populations suggest intraspecies differences in resistance to pathogens. Dev Comp Immunol (2009) 1.12
Structural resolution of carbohydrate positional and structural isomers based on gas-phase ion mobility-mass spectrometry. Phys Chem Chem Phys (2010) 1.12
Race disparities in Wilms tumor incidence and biology. J Surg Res (2011) 1.11
Proteomic analysis illuminates a novel structural definition of the claustrum and insula. Cereb Cortex (2009) 1.11
Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase. J Med Chem (2009) 1.08
High spatial resolution imaging mass spectrometry and classical histology on a single tissue section. J Mass Spectrom (2011) 1.07
Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism. Proc Natl Acad Sci U S A (2013) 1.07
The influence and utility of varying field strength for the separation of tryptic peptides by ion mobility-mass spectrometry. J Am Soc Mass Spectrom (2005) 1.07
Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry. J Am Soc Mass Spectrom (2011) 1.07
Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides. Inflamm Bowel Dis (2010) 1.06
Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa. Int J Cancer (2012) 1.06
Detection of pre-neoplastic and neoplastic prostate disease by MALDI profiling of urine. Biochem Biophys Res Commun (2006) 1.05
Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers. J Neurochem (2002) 1.05
Differentiating proteomic biomarkers in breast cancer by laser capture microdissection and MALDI MS. J Proteome Res (2008) 1.05
Dual analysis for mycobacteria and propionibacteria in sarcoidosis BAL. J Clin Immunol (2012) 1.04
Molecular imaging of thin mammalian tissue sections by mass spectrometry. Curr Opin Biotechnol (2006) 1.04
Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition. Biochemistry (2008) 1.04
Ion mobility-mass spectrometry: time-dispersive instrumentation. Anal Chem (2015) 1.04
Monitoring mouse prostate development by profiling and imaging mass spectrometry. Mol Cell Proteomics (2007) 1.03
Direct molecular analysis of whole-body animal tissue sections by MALDI imaging mass spectrometry. Methods Mol Biol (2010) 1.03
Mass spectrometry of intracellular and membrane proteins using cleavable detergents. Anal Chem (2003) 1.03