Published in Trends Biotechnol on February 02, 2011
Tissue imaging using nanospray desorption electrospray ionization mass spectrometry. Anal Chem (2011) 1.50
Nondestructive, histologically compatible tissue imaging by desorption electrospray ionization mass spectrometry. Chembiochem (2011) 1.34
Enhanced sensitivity for high spatial resolution lipid analysis by negative ion mode matrix assisted laser desorption ionization imaging mass spectrometry. Anal Chem (2012) 1.25
Primer on agar-based microbial imaging mass spectrometry. J Bacteriol (2012) 1.22
Analysis of intact protein isoforms by mass spectrometry. J Biol Chem (2011) 1.15
Top Down proteomics: facts and perspectives. Biochem Biophys Res Commun (2014) 1.14
Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity. Semin Immunopathol (2011) 1.13
MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications. Histochem Cell Biol (2011) 1.12
Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations. Anal Chem (2012) 0.97
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites. Adv Drug Deliv Rev (2013) 0.96
Significantly increased monounsaturated lipids relative to polyunsaturated lipids in six types of cancer microenvironment are observed by mass spectrometry imaging. Sci Rep (2014) 0.95
A vision for better health: mass spectrometry imaging for clinical diagnostics. Clin Chim Acta (2012) 0.90
Detailed structural analysis of lipids directly on tissue specimens using a MALDI-SpiralTOF-Reflectron TOF mass spectrometer. PLoS One (2012) 0.87
Application of metabolomics in thyroid cancer research. Int J Endocrinol (2015) 0.84
Current strategies and findings in clinically relevant post-translational modification-specific proteomics. Expert Rev Proteomics (2015) 0.83
Relevant phosphoproteomic and mass spectrometry: approaches useful in clinical research. Clin Transl Med (2012) 0.83
Activity-based probes linked with laser-cleavable mass tags for signal amplification in imaging mass spectrometry: analysis of serine hydrolase enzymes in mammalian tissue. Anal Chem (2012) 0.77
Whole Reproductive System Non-Negative Matrix Factorization Mass Spectrometry Imaging of an Early-Stage Ovarian Cancer Mouse Model. PLoS One (2016) 0.77
Mass Spectrometry-based Proteomics and Peptidomics for Systems Biology and Biomarker Discovery. Front Biol (Beijing) (2012) 0.77
Quantification of the heterogeneity of prognostic cellular biomarkers in ewing sarcoma using automated image and random survival forest analysis. PLoS One (2014) 0.76
3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors. Sci Rep (2016) 0.76
Imaging mass spectrometry in papillary thyroid carcinoma for the identification and validation of biomarker proteins. J Korean Med Sci (2014) 0.76
Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium - application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data. Proteomics (2016) 0.75
Mass Spectrometry Imaging and Identification of Peptides Associated with Cephalic Ganglia Regeneration in Schmidtea mediterranea. J Biol Chem (2016) 0.75
Proteome analysis of the macroscopically affected colonic mucosa of Crohn's disease and intestinal tuberculosis. Sci Rep (2016) 0.75
A Nanostructured Matrices Assessment to Study Drug Distribution in Solid Tumor Tissues by Mass Spectrometry Imaging. Nanomaterials (Basel) (2017) 0.75
LRP6 is identified as a potential prognostic marker for oral squamous cell carcinoma via MALDI-IMS. Cell Death Dis (2017) 0.75
Formaldehyde fixation. J Histochem Cytochem (1985) 5.89
Imaging mass spectrometry. Mass Spectrom Rev (2007) 3.79
Sublimation as a method of matrix application for mass spectrometric imaging. J Am Soc Mass Spectrom (2007) 3.46
Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Anal Chem (2006) 3.03
Automated acoustic matrix deposition for MALDI sample preparation. Anal Chem (2006) 2.83
Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression. Clin Cancer Res (2004) 2.41
Molecular imaging of proteins in tissues by mass spectrometry. Proc Natl Acad Sci U S A (2008) 2.38
Direct analysis and MALDI imaging of formalin-fixed, paraffin-embedded tissue sections. J Proteome Res (2007) 2.38
Tissue ischemia time affects gene and protein expression patterns within minutes following surgical tumor excision. Biotechniques (2004) 2.36
Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction. Nat Methods (2008) 2.24
Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry. J Mass Spectrom (2007) 2.20
Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry. J Mass Spectrom (2003) 2.15
Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res (2005) 2.06
A novel histology-directed strategy for MALDI-MS tissue profiling that improves throughput and cellular specificity in human breast cancer. Mol Cell Proteomics (2006) 2.03
Enhancement of protein sensitivity for MALDI imaging mass spectrometry after chemical treatment of tissue sections. J Am Soc Mass Spectrom (2008) 1.96
High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry. Proteomics (2008) 1.91
Integrating histology and imaging mass spectrometry. Anal Chem (2004) 1.86
Solvent-free matrix dry-coating for MALDI imaging of phospholipids. J Am Soc Mass Spectrom (2008) 1.86
Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue. Clin Cancer Res (2009) 1.60
Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Nat Methods (2007) 1.58
Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation. J Lipid Res (2009) 1.58
Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer Res (2004) 1.53
Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry. J Proteome Res (2010) 1.48
Heat-induced antigen retrieval: mechanisms and application to histochemistry. Prog Histochem Cytochem (2006) 1.44
Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation. Clin Cancer Res (2010) 1.43
Discrimination of human astrocytoma subtypes by lipid analysis using desorption electrospray ionization imaging mass spectrometry. Angew Chem Int Ed Engl (2010) 1.43
Proteomic patterns of preinvasive bronchial lesions. Am J Respir Crit Care Med (2005) 1.32
A 25-signal proteomic signature and outcome for patients with resected non-small-cell lung cancer. J Natl Cancer Inst (2007) 1.30
Imaging mass spectrometry reveals unique protein profiles during embryo implantation. Endocrinology (2008) 1.28
Identifying prostate carcinoma by MALDI-Imaging. Int J Mol Med (2007) 1.27
Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma. J Proteome Res (2010) 1.27
Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry. Mol Cancer (2010) 1.19
Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids. J Proteomics (2010) 1.12
Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides. Inflamm Bowel Dis (2010) 1.06
Differentiating proteomic biomarkers in breast cancer by laser capture microdissection and MALDI MS. J Proteome Res (2008) 1.05
Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix-assisted laser desorption/ionisation mass spectrometry. Rapid Commun Mass Spectrom (2007) 1.02
Gastric cancer-specific protein profile identified using endoscopic biopsy samples via MALDI mass spectrometry. J Proteome Res (2010) 0.98
MALDI MS imaging of amyloid. Methods Enzymol (2006) 0.95
Effect of combined oral contraceptives on breast epithelial proliferation in young women. Breast J (2008) 0.92
Demonstration of amyloid protein AA in old museum specimens. Arch Pathol Lab Med (1984) 0.88
Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS. Mol Cell Proteomics (2009) 0.87
A mass spectrometry primer for mass spectrometry imaging. Methods Mol Biol (2010) 0.84
Improving spot homogeneity by using polymer substrates in matrix-assisted laser desorption/ionization mass spectrometry of oligonucleotides. Anal Chem (2001) 0.79
Primary cell culture of human adenocarcinomas--practical considerations. Roum Arch Microbiol Immunol (2009) 0.79
Tissue microarrays from frozen tissues-OCT technique. Methods Mol Biol (2010) 0.77
Relationship between the prolongation of warm ischemia and the maximum available preservation period. Surgery (1977) 0.77
Metal chelation and inhibition of bacterial growth in tissue abscesses. Science (2008) 4.55
MALDI imaging mass spectrometry: molecular snapshots of biochemical systems. Nat Methods (2007) 4.20
Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet (2003) 4.01
Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Anal Chem (2006) 3.03
Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation. J Mass Spectrom (2003) 2.84
Automated acoustic matrix deposition for MALDI sample preparation. Anal Chem (2006) 2.83
Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression. Clin Cancer Res (2004) 2.41
Molecular imaging of proteins in tissues by mass spectrometry. Proc Natl Acad Sci U S A (2008) 2.38
New developments in profiling and imaging of proteins from tissue sections by MALDI mass spectrometry. J Proteome Res (2006) 2.33
Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. Development (2005) 2.31
Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction. Nat Methods (2008) 2.24
Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry. J Mass Spectrom (2007) 2.20
Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry. J Mass Spectrom (2003) 2.15
MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue. Anal Chem (2008) 2.09
Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res (2005) 2.06
A novel histology-directed strategy for MALDI-MS tissue profiling that improves throughput and cellular specificity in human breast cancer. Mol Cell Proteomics (2006) 2.03
Enhancement of protein sensitivity for MALDI imaging mass spectrometry after chemical treatment of tissue sections. J Am Soc Mass Spectrom (2008) 1.96
High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry. Proteomics (2008) 1.91
Integrating histology and imaging mass spectrometry. Anal Chem (2004) 1.86
Solvent-free matrix dry-coating for MALDI imaging of phospholipids. J Am Soc Mass Spectrom (2008) 1.86
Proteome analysis of human colon cancer by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics (2004) 1.82
Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research. Chem Rev (2013) 1.80
Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am J Pathol (2004) 1.76
Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis. Int J Mass Spectrom (2007) 1.73
Molecular imaging by mass spectrometry--looking beyond classical histology. Nat Rev Cancer (2010) 1.72
MALDI-MS-based imaging of small molecules and proteins in tissues. Curr Opin Chem Biol (2006) 1.66
Tissue profiling by mass spectrometry: a review of methodology and applications. Mol Cell Proteomics (2005) 1.64
Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry. J Am Soc Mass Spectrom (2005) 1.62
Imaging of intact tissue sections: moving beyond the microscope. J Biol Chem (2011) 1.60
Mass spectrometric profiling of intact biological tissue by using desorption electrospray ionization. Angew Chem Int Ed Engl (2005) 1.59
The pros and cons of peptide-centric proteomics. Nat Biotechnol (2010) 1.58
Monitoring the inflammatory response to infection through the integration of MALDI IMS and MRI. Cell Host Microbe (2012) 1.58
Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Nat Methods (2007) 1.58
Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation. J Lipid Res (2009) 1.58
Direct imaging of single cells and tissue at sub-cellular spatial resolution using transmission geometry MALDI MS. J Mass Spectrom (2012) 1.57
Profiling and imaging of tissues by imaging ion mobility-mass spectrometry. J Mass Spectrom (2007) 1.55
Imaging mass spectrometry: principles and potentials. Toxicol Pathol (2005) 1.54
Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer Res (2004) 1.53
Matrix sublimation/recrystallization for imaging proteins by mass spectrometry at high spatial resolution. Anal Chem (2011) 1.52
Identification of an Acinetobacter baumannii zinc acquisition system that facilitates resistance to calprotectin-mediated zinc sequestration. PLoS Pathog (2012) 1.47
Imaging mass spectrometry: a new tool to investigate the spatial organization of peptides and proteins in mammalian tissue sections. Curr Opin Chem Biol (2002) 1.47
Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs. Am J Physiol Lung Cell Mol Physiol (2008) 1.46
Proteomic patterns and prediction of glomerulosclerosis and its mechanisms. J Am Soc Nephrol (2005) 1.44
Assessing protein patterns in disease using imaging mass spectrometry. J Proteome Res (2004) 1.44
Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation. Clin Cancer Res (2010) 1.43
Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry. Electrophoresis (2002) 1.42
Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer. J Thorac Oncol (2007) 1.40
Instrument design and characterization for high resolution MALDI-MS imaging of tissue sections. J Mass Spectrom (2007) 1.34
Proteomic patterns of preinvasive bronchial lesions. Am J Respir Crit Care Med (2005) 1.32
3D imaging by mass spectrometry: a new frontier. Anal Chem (2012) 1.31
MALDI imaging of lipid biochemistry in tissues by mass spectrometry. Chem Rev (2011) 1.29
Proteomic analysis of formalin-fixed paraffin-embedded tissue by MALDI imaging mass spectrometry. Nat Protoc (2011) 1.28
Imaging mass spectrometry reveals unique protein profiles during embryo implantation. Endocrinology (2008) 1.28
Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma. J Proteome Res (2010) 1.27
Direct analysis of laser capture microdissected cells by MALDI mass spectrometry. J Am Soc Mass Spectrom (2002) 1.24
Structural characterization of phospholipids and peptides directly from tissue sections by MALDI traveling-wave ion mobility-mass spectrometry. Anal Chem (2010) 1.22
Biomarker discovery by imaging mass spectrometry: transthyretin is a biomarker for gentamicin-induced nephrotoxicity in rat. Mol Cell Proteomics (2006) 1.19
MALDI imaging mass spectrometry of integral membrane proteins from ocular lens and retinal tissue. J Proteome Res (2009) 1.18
High-speed MALDI-TOF imaging mass spectrometry: rapid ion image acquisition and considerations for next generation instrumentation. J Am Soc Mass Spectrom (2011) 1.18
MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infect Immun (2013) 1.17
Imaging mass spectrometry: a new tool for pathology in a molecular age. Proteomics Clin Appl (2013) 1.17
Decreased striatal levels of PEP-19 following MPTP lesion in the mouse. J Proteome Res (2006) 1.17
Profiling and imaging proteins in the mouse epididymis by imaging mass spectrometry. Proteomics (2003) 1.17
Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry. J Proteome Res (2004) 1.17
Alterations in the diabetic myocardial proteome coupled with increased myocardial oxidative stress underlies diabetic cardiomyopathy. J Mol Cell Cardiol (2007) 1.15
Characterization of glycosylation sites of the epidermal growth factor receptor. Biochemistry (2003) 1.14
MALDI mass spectrometry for direct tissue analysis: a new tool for biomarker discovery. J Proteome Res (2005) 1.14
From whole-body sections down to cellular level, multiscale imaging of phospholipids by MALDI mass spectrometry. Mol Cell Proteomics (2010) 1.14
Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients. Cancer Epidemiol Biomarkers Prev (2010) 1.13
Direct tissue analysis by matrix-assisted laser desorption ionization mass spectrometry: application to kidney biology. Semin Nephrol (2007) 1.13
Variations in the expressed antimicrobial peptide repertoire of northern leopard frog (Rana pipiens) populations suggest intraspecies differences in resistance to pathogens. Dev Comp Immunol (2009) 1.12
Race disparities in Wilms tumor incidence and biology. J Surg Res (2011) 1.11
Proteomic analysis illuminates a novel structural definition of the claustrum and insula. Cereb Cortex (2009) 1.11
Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase. J Med Chem (2009) 1.08
High spatial resolution imaging mass spectrometry and classical histology on a single tissue section. J Mass Spectrom (2011) 1.07
Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry. J Am Soc Mass Spectrom (2011) 1.07
Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides. Inflamm Bowel Dis (2010) 1.06
Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa. Int J Cancer (2012) 1.06
Differentiating proteomic biomarkers in breast cancer by laser capture microdissection and MALDI MS. J Proteome Res (2008) 1.05
Detection of pre-neoplastic and neoplastic prostate disease by MALDI profiling of urine. Biochem Biophys Res Commun (2006) 1.05
Prostaglandin H2 (PGH2) accelerates formation of amyloid beta1-42 oligomers. J Neurochem (2002) 1.05
Dual analysis for mycobacteria and propionibacteria in sarcoidosis BAL. J Clin Immunol (2012) 1.04
Molecular imaging of thin mammalian tissue sections by mass spectrometry. Curr Opin Biotechnol (2006) 1.04
Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition. Biochemistry (2008) 1.04
Monitoring mouse prostate development by profiling and imaging mass spectrometry. Mol Cell Proteomics (2007) 1.03
Direct molecular analysis of whole-body animal tissue sections by MALDI imaging mass spectrometry. Methods Mol Biol (2010) 1.03
Mass spectrometry of intracellular and membrane proteins using cleavable detergents. Anal Chem (2003) 1.03
The anti-tumorigenic properties of peroxisomal proliferator-activated receptor alpha are arachidonic acid epoxygenase-mediated. J Biol Chem (2010) 1.03
Protein signatures for survival and recurrence in metastatic melanoma. J Proteomics (2011) 1.02
Matrix pre-coated MALDI MS targets for small molecule imaging in tissues. J Am Soc Mass Spectrom (2011) 1.01
In situ molecular imaging of proteins in tissues using mass spectrometry. Anal Bioanal Chem (2008) 1.01
Combination detergent/MALDI matrix: functional cleavable detergents for mass spectrometry. Anal Chem (2005) 1.01
Structural and functional characterization of the monomeric U-box domain from E4B. Biochemistry (2010) 1.01
Imaging mass spectrometry: Towards clinical diagnostics. Proteomics Clin Appl (2008) 1.00
Matrix-assisted laser desorption ionization imaging mass spectrometry: in situ molecular mapping. Biochemistry (2013) 0.99
Multivariable difference gel electrophoresis and mass spectrometry: a case study on transforming growth factor-beta and ERBB2 signaling. Mol Cell Proteomics (2006) 0.98
Lung cancer diagnosis from proteomic analysis of preinvasive lesions. Cancer Res (2011) 0.98
Gastric cancer-specific protein profile identified using endoscopic biopsy samples via MALDI mass spectrometry. J Proteome Res (2010) 0.98
MALDI imaging and in situ identification of integral membrane proteins from rat brain tissue sections. Anal Chem (2013) 0.98