Published in Oncogene on February 15, 2010
Temporal regulation of EGF signalling networks by the scaffold protein Shc1. Nature (2013) 2.33
Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nat Genet (2011) 2.02
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration. Nat Genet (2015) 1.66
LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma. Proc Natl Acad Sci U S A (2015) 1.49
The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting. EMBO J (2012) 1.18
Molecular alterations in key-regulator genes among patients with T4 breast carcinoma. BMC Cancer (2010) 0.82
A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. Mol Cancer (2015) 0.80
Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer. Int J Clin Exp Pathol (2013) 0.80
AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions. Sci Rep (2014) 0.76
Allosteric properties of PH domains in Arf regulatory proteins. Cell Logist (2016) 0.76
ArfGAPs: key regulators for receptor sorting. Receptors Clin Investig (2014) 0.75
Arf proteins in cancer cell migration. Small GTPases (2016) 0.75
No Significant Effect of ASAP1 Gene Variants on the Susceptibility to Tuberculosis in Chinese Population. Medicine (Baltimore) (2016) 0.75
Focus on cutaneous and uveal melanoma specificities. Genes Dev (2017) 0.75
WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update. Eur Respir J (2011) 8.96
Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med (1985) 8.45
Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity (1999) 8.33
Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med (1997) 7.42
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J (2001) 6.85
Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med (1989) 5.78
Detection and in situ identification of representatives of a widely distributed new bacterial phylum. FEMS Microbiol Lett (1997) 5.20
Complete genome sequence of the marine planctomycete Pirellula sp. strain 1. Proc Natl Acad Sci U S A (2003) 4.16
Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nat Genet (1998) 3.94
Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. An NSABP update. Cancer (1983) 3.94
Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation. N Engl J Med (1985) 3.41
The accuracy of clinical nodal staging and of limited axillary dissection as a determinant of histologic nodal status in carcinoma of the breast. Surg Gynecol Obstet (1981) 3.11
ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development (1997) 3.04
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry (2004) 2.98
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid. Oncogene (2001) 2.67
The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments. Environ Microbiol (2004) 2.66
Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response. J Allergy Clin Immunol (2001) 2.62
Efficient gene transfer into human hepatocytes by baculovirus vectors. Proc Natl Acad Sci U S A (1995) 2.60
The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J Exp Med (1998) 2.55
Surgical pathology of primary cardiac and pericardial tumors. Eur J Cardiothorac Surg (1997) 2.43
Understanding the Italian Experience. Br J Psychiatry (1985) 2.41
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc Natl Acad Sci U S A (1999) 2.33
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. Circulation (1997) 2.20
Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia. Ann Neurol (1994) 2.19
Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching. Nat Genet (1996) 2.13
Transfer of airway skills from manikin training to patient: success of ventilation with facemask or LMA-Supreme(TM) by medical students. Anaesthesia (2013) 2.09
Mutations in the gene encoding epsilon-sarcoglycan cause myoclonus-dystonia syndrome. Nat Genet (2001) 2.06
Neoadjuvant therapy of esophageal squamous cell carcinoma: response evaluation by positron emission tomography. Ann Surg (2001) 2.04
Early mycological treatment failure in AIDS-associated cryptococcal meningitis. Clin Infect Dis (1999) 2.04
Fluconazole combined with flucytosine for treatment of cryptococcal meningitis in patients with AIDS. Clin Infect Dis (1994) 1.99
Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis. Cell (1995) 1.99
[Monitoring of liver function in the critically ill]. Anaesthesist (2014) 1.99
Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study. Allergy (2012) 1.88
[Generation Y : recruitment, retention and development]. Anaesthesist (2011) 1.86
Does thyroid supplementation accelerate tricyclic antidepressant response? A review and meta-analysis of the literature. Am J Psychiatry (2001) 1.85
Transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting. Circulation (2005) 1.83
CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur J Immunol (1997) 1.79
The proliferative function of basal cells in the normal and hyperplastic human prostate. Prostate (1994) 1.79
Lone atrial fibrillation: prognostic differences between paroxysmal and chronic forms after 10 years of follow-up. Am Heart J (1999) 1.76
Endocrine-paracrine cell types in the prostate and prostatic adenocarcinoma are postmitotic cells. Hum Pathol (1995) 1.73
Rationale for integrating early postoperative intraperitoneal chemotherapy into the surgical treatment of gastrointestinal cancer. Semin Oncol (1989) 1.65
Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. Hum Mol Genet (1996) 1.65
Growth rate of 147 mammary carcinomas. Cancer (1980) 1.62
Early postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer: pharmacological studies. Cancer Res (1990) 1.61
Epidemiology of dilated cardiomyopathy. A prospective post-mortem study of 5252 necropsies. The Heart Muscle Disease Study Group. Eur Heart J (1997) 1.58
Does prophylaxis-delay in bipolar disorder influence outcome? Results from a long-term study of 147 patients. Acta Psychiatr Scand (2003) 1.58
X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. Proc Natl Acad Sci U S A (1995) 1.58
Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines. Eur J Immunol (1997) 1.56
Cerebral and extracerebral release of protein S100B in cardiac surgical patients. Anaesthesia (2004) 1.55
Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life. Allergy (2009) 1.54
Differential expression pattern of heme oxygenase-1/heat shock protein 32 and nitric oxide synthase-II and their impact on liver injury in a rat model of hemorrhage and resuscitation. Crit Care Med (1999) 1.53
Hepatitis C and liver fibrosis. Cell Death Differ (2003) 1.53
Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis. Acta Psychiatr Scand (2013) 1.52
Mass fainting at rock concerts. N Engl J Med (1995) 1.51
Syncope and near-death experience. Lancet (1994) 1.50
Mixed agonistic-antagonistic cytokine response in whole blood from patients undergoing abdominal aortic aneurysm repair. Intensive Care Med (1999) 1.49
Outcome after emergency surgery for cancer of the large intestine. Br J Surg (1991) 1.48
Effect of severity of meningitis on fungicidal activity of flucytosine combined with fluconazole in a murine model of cryptococcal meningitis. Antimicrob Agents Chemother (1997) 1.46
Skinfold thickness measurements in obese subjects. Am J Clin Nutr (1990) 1.45
Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J (1995) 1.45
Mildly oxidized low density lipoprotein induces contraction of human endothelial cells through activation of Rho/Rho kinase and inhibition of myosin light chain phosphatase. J Biol Chem (1999) 1.45
Myoclonus in patients treated with clozapine: a case series. J Clin Psychiatry (1995) 1.45
Dynamics of viral variants in HIV-1 Nef and specific cytotoxic T lymphocytes in vivo. J Immunol (1996) 1.43
Staphylococcal alpha-toxin elicits hypertension in isolated rabbit lungs. Evidence for thromboxane formation and the role of extracellular calcium. J Clin Invest (1984) 1.43
Bispectral index-controlled anaesthesia for electroconvulsive therapy. Eur J Anaesthesiol (2006) 1.43
Sequence constraints and recognition by CTL of an HLA-B27-restricted HIV-1 gag epitope. J Immunol (1995) 1.42
Viral vectors for gene transfer: a review of their use in the treatment of human diseases. Drugs (2000) 1.42
Effect of fluconazole on fungicidal activity of flucytosine in murine cryptococcal meningitis. Antimicrob Agents Chemother (1996) 1.41
Time experience and time judgment in major depression, mania and healthy subjects. A controlled study of 93 subjects. Acta Psychiatr Scand (2004) 1.40
[Lithium in the treatment of acute depression]. Fortschr Neurol Psychiatr (1998) 1.40
The value of preoperative radiotherapy in esophageal cancer: results of a study of the E.O.R.T.C. World J Surg (1987) 1.40
Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells. EMBO J (1989) 1.40
[Effects of desflurane on liver microcirculation in comparison with isoflurane and pentobarbital. An intravital microscopy study in the rat]. Anasthesiol Intensivmed Notfallmed Schmerzther (1995) 1.39
[Fluid resuscitation in hemorrhage]. Anaesthesist (2014) 1.39
[Extravasal position of central venous catheters despite unsuspicious ECG-guidance]. Anasthesiol Intensivmed Notfallmed Schmerzther (2005) 1.39
[Comparison of premedication regimes. A randomized, controlled trial]. Anaesthesist (2007) 1.39
Cerebrovascular complications of bacterial meningitis in adults. Neurology (1992) 1.38
Benefits from aerobic exercise in patients with major depression: a pilot study. Br J Sports Med (2001) 1.35
Human colorectal cancer: high frequency of deletions at chromosome 1p35. Cancer Res (1990) 1.33
Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. Am J Pathol (2001) 1.32
Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages. J Neuroimmunol (2001) 1.31
Gene expression patterns associated with the metastatic phenotype in rodent and human tumors. Cancer Res (2001) 1.31
Stereotactic radiotherapy of targets in the lung and liver. Strahlenther Onkol (2001) 1.30
Mildly oxidized low density lipoprotein rapidly stimulates via activation of the lysophosphatidic acid receptor Src family and Syk tyrosine kinases and Ca2+ influx in human platelets. J Biol Chem (2000) 1.29
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis. Gut (2002) 1.29
Sendai virus infection induces apoptosis through activation of caspase-8 (FLICE) and caspase-3 (CPP32). J Virol (1999) 1.27
Upregulation of miR-21 by Ras in vivo and its role in tumor growth. Oncogene (2010) 1.25
Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis. Cell Growth Differ (2000) 1.25
Biotechnology and the European public. Nat Biotechnol (2000) 1.25
Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. EMBO J (1997) 1.25
An evaluation of fit factors and dissolution efficiency for the comparison of in vitro dissolution profiles. J Pharm Biomed Anal (1998) 1.25
Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). Gene Ther (2005) 1.24
Prospective randomized trial between two doses of granulocyte colony-stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent or refractory solid tumors: a children's cancer group report. J Pediatr Hematol Oncol (2001) 1.24
Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I. J Exp Med (1999) 1.24
Gene transfer into hepatocytes and human liver tissue by baculovirus vectors. Hum Gene Ther (1996) 1.23
Expression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases. Am J Pathol (1991) 1.22
Phosphorylation of human progesterone receptor by cyclin-dependent kinase 2 on three sites that are authentic basal phosphorylation sites in vivo. Mol Endocrinol (1997) 1.22
Are nitrite and N-nitroso compounds in gastric juice risk factors for carcinoma in the operated stomach? Lancet (1980) 1.21
Multidirectional differentiation in the normal, hyperplastic, and neoplastic human prostate: simultaneous demonstration of cell-specific epithelial markers. Hum Pathol (1994) 1.21