Published in PLoS Negl Trop Dis on February 09, 2010
Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nat Rev Microbiol (2010) 2.10
Heme and blood-feeding parasites: friends or foes? Parasit Vectors (2010) 1.07
Gene expression patterns in larval Schistosoma mansoni associated with infection of the mammalian host. PLoS Negl Trop Dis (2011) 1.07
Profiles of small non-coding RNAs in Schistosoma japonicum during development. PLoS Negl Trop Dis (2011) 1.02
Gene Atlasing of digestive and reproductive tissues in Schistosoma mansoni. PLoS Negl Trop Dis (2011) 0.98
An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathog (2014) 0.93
Cercarial transformation and in vitro cultivation of Schistosoma mansoni schistosomules. J Vis Exp (2011) 0.92
A research agenda for helminth diseases of humans: basic research and enabling technologies to support control and elimination of helminthiases. PLoS Negl Trop Dis (2012) 0.91
Whole-organ isolation approach as a basis for tissue-specific analyses in Schistosoma mansoni. PLoS Negl Trop Dis (2013) 0.88
Functional expression of a novel Kunitz type protease inhibitor from the human blood fluke Schistosoma mansoni. Parasit Vectors (2015) 0.88
Comparative study of transcriptome profiles of mechanical- and skin-transformed Schistosoma mansoni schistosomula. PLoS Negl Trop Dis (2013) 0.87
Characterization of the phytochelatin synthase of Schistosoma mansoni. PLoS Negl Trop Dis (2011) 0.86
Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini. PLoS Negl Trop Dis (2012) 0.86
Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Front Immunol (2015) 0.85
Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni. PLoS Negl Trop Dis (2012) 0.84
Identification and characterization of argonaute protein, Ago2 and its associated small RNAs in Schistosoma japonicum. PLoS Negl Trop Dis (2012) 0.84
Induction of protective immune responses against schistosomiasis using functionally active cysteine peptidases. Front Genet (2014) 0.84
Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'. PLoS Negl Trop Dis (2014) 0.83
Application of RNAi to Genomic Drug Target Validation in Schistosomes. PLoS Negl Trop Dis (2015) 0.83
Schistosoma tegument proteins in vaccine and diagnosis development: an update. J Parasitol Res (2012) 0.83
Solution structure, membrane interactions, and protein binding partners of the tetraspanin Sm-TSP-2, a vaccine antigen from the human blood fluke Schistosoma mansoni. J Biol Chem (2014) 0.81
Sm10.3, a member of the micro-exon gene 4 (MEG-4) family, induces erythrocyte agglutination in vitro and partially protects vaccinated mice against Schistosoma mansoni infection. PLoS Negl Trop Dis (2014) 0.79
Discovery of novel Schistosoma japonicum antigens using a targeted protein microarray approach. Parasit Vectors (2014) 0.79
Functional characterisation of Schistosoma japonicum acetylcholinesterase. Parasit Vectors (2016) 0.76
Sex-Biased Transcriptome of Schistosoma mansoni: Host-Parasite Interaction, Genetic Determinants and Epigenetic Regulators Are Associated with Sexual Differentiation. PLoS Negl Trop Dis (2016) 0.76
Development of "-omics" research in Schistosoma spp. and -omics-based new diagnostic tools for schistosomiasis. Front Microbiol (2014) 0.75
Molecular characterization of host-parasite cell signalling in Schistosoma mansoni during early development. Sci Rep (2016) 0.75
Comparative sequence analysis reveals regulation of genes in developing schistosomula of Schistosoma mansoni exposed to host portal serum. PLoS One (2017) 0.75
Lysosome-associated membrane glycoprotein (LAMP)--preliminary study on a hidden antigen target for vaccination against schistosomiasis. Sci Rep (2015) 0.75
Locating proteins in the cell using TargetP, SignalP and related tools. Nat Protoc (2007) 19.50
The immunobiology of schistosomiasis. Nat Rev Immunol (2002) 6.07
The genome of the blood fluke Schistosoma mansoni. Nature (2009) 5.94
Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project. Nat Biotechnol (2006) 5.92
The Schistosoma japonicum genome reveals features of host-parasite interplay. Nature (2009) 4.19
Microarray validation: factors influencing correlation between oligonucleotide microarrays and real-time PCR. Biol Proced Online (2006) 3.70
Current status of vaccines for schistosomiasis. Clin Microbiol Rev (2008) 3.47
Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Curr Opin Infect Dis (2008) 3.31
Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni. Nat Genet (2003) 2.66
Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nat Med (2006) 2.59
Cultivation of Schistosoma mansoni in vitro. I. Establishment of cultures from cercariae and development until pairing. J Parasitol (1981) 2.04
Acquisition of murine major histocompatibility complex gene products by schistosomula of Schistosoma mansoni. J Exp Med (1978) 1.98
Proteins exposed at the adult schistosome surface revealed by biotinylation. Mol Cell Proteomics (2005) 1.81
Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth. Mol Biochem Parasitol (2005) 1.73
Schistosoma mansoni: rapid isolation and purification of schistosomula of different developmental stages by centrifugation on discontinuous density gradients of Percoll. Exp Parasitol (1982) 1.66
Acquisition of human antigens by Schistosoma mansoni during cultivation in vitro. Nature (1971) 1.59
Schistosoma mansoni tegument protein Sm29 is able to induce a Th1-type of immune response and protection against parasite infection. PLoS Negl Trop Dis (2008) 1.58
Developmental gene expression profiles of the human pathogen Schistosoma japonicum. BMC Genomics (2009) 1.56
Schistosome membrane proteins as vaccines. Int J Parasitol (2006) 1.52
Acquisition of human blood group antigens by Schistosoma mansoni. Clin Exp Immunol (1976) 1.50
Purification and characterization of an elastinolytic proteinase secreted by cercariae of Schistosoma mansoni. J Biol Chem (1985) 1.43
The cytoskeleton and motor proteins of human schistosomes and their roles in surface maintenance and host-parasite interactions. Bioessays (2004) 1.42
RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade. Mol Biochem Parasitol (2007) 1.38
Blood 'n' guts: an update on schistosome digestive peptidases. Trends Parasitol (2004) 1.35
An immunogenic Mr 23,000 integral membrane protein of Schistosoma mansoni worms that closely resembles a human tumor-associated antigen. J Immunol (1990) 1.35
Structural and phylogenetic analyses of RGD-CAP/beta ig-h3, a fasciclin-like adhesion protein expressed in chick chondrocytes. Biochim Biophys Acta (1998) 1.26
Inhibition of the complement membrane attack complex by Schistosoma mansoni paramyosin. Infect Immun (2003) 1.25
Mass spectrometric analysis of the Schistosoma mansoni tegumental sub-proteome. J Proteome Res (2005) 1.23
Cercarial elastase is encoded by a functionally conserved gene family across multiple species of schistosomes. J Biol Chem (2002) 1.22
Gene expression patterns during adaptation of a helminth parasite to different environmental niches. Genome Biol (2007) 1.20
Microarray analysis identifies genes preferentially expressed in the lung schistosomulum of Schistosoma mansoni. Int J Parasitol (2005) 1.19
Glycomics analysis of Schistosoma mansoni egg and cercarial secretions. Mol Cell Proteomics (2007) 1.19
Proteomic analysis of the schistosome tegument and its surface membranes. Mem Inst Oswaldo Cruz (2006) 1.18
Natural versus drug-induced resistance in Schistosoma mansoni infection. Parasitol Today (2000) 1.17
The radiation-attenuated vaccine against schistosomes in animal models: paradigm for a human vaccine? Adv Parasitol (1997) 1.14
Receptor for Fc on the surfaces of schistosomes. Infect Immun (2001) 1.14
Tissue specific profiling of females of Schistosoma japonicum by integrated laser microdissection microscopy and microarray analysis. PLoS Negl Trop Dis (2009) 1.10
Antigens derived from lung-stage larvae of Schistosoma mansoni are efficient stimulators of proliferation and gamma interferon secretion by lymphocytes from mice vaccinated with attenuated larvae. Infect Immun (1995) 1.10
Cloning, characterization, and functional expression of cDNAs encoding glucose transporter proteins from the human parasite Schistosoma mansoni. J Biol Chem (1994) 1.10
Oligonucleotide microarray analysis of strain- and gender-associated gene expression in the human blood fluke, Schistosoma japonicum. Mol Cell Probes (2006) 1.09
Immune effector mechanisms against schistosomiasis: looking for a chink in the parasite's armour. Trends Parasitol (2009) 1.09
Manipulating the manipulators: advances in parasitic helminth transgenesis and RNAi. Trends Parasitol (2007) 1.07
Schistosomes--proteomics studies for potential novel vaccines and drug targets. Drug Discov Today (2009) 1.07
The ultrastructural architecture of the adult Schistosoma japonicum tegument. Int J Parasitol (2003) 1.05
Transformation of cercariae to schistosomula: a quantitative comparison of transformation techniques and of infectivity by different injection routes of the organisms produced. J Helminthol (1976) 1.04
Human IgE response to the Schistosoma haematobium 22.6 kDa antigen. Parasite Immunol (2005) 1.04
Proteomic analysis of the tegument and excretory-secretory products of adult Schistosoma bovis worms. Proteomics (2006) 1.03
Schistosoma mansoni ex vivo lung-stage larvae excretory-secretory antigens as vaccine candidates against schistosomiasis. Vaccine (2008) 1.03
Cloning of the proteinase that facilitates infection by schistosome parasites. J Biol Chem (1988) 1.01
Evidence for adsorption of heterospecific host immunoglobulin on the tegument of Schistosoma mansoni. J Immunol (1977) 1.00
Immunization with Schistosoma mansoni 22.6 kDa antigen induces partial protection against experimental infection in a recombinant protein form but not as DNA vaccine. Immunobiology (2005) 1.00
Tegumental expression of a novel type II receptor serine/threonine kinase (SmRK2) in Schistosoma mansoni. Mol Biochem Parasitol (2004) 0.98
Transcriptional profiles of adult male and female Schistosoma japonicum in response to insulin reveal increased expression of genes involved in growth and development. Int J Parasitol (2009) 0.95
Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections. Int J Infect Dis (2008) 0.89
Microarray based analysis of temperature and oxidative stress induced messenger RNA in Schistosoma mansoni. Mol Biochem Parasitol (2008) 0.89
The Role of Microscopy in the Investigation of Paramyosin as a Vaccine Candidate against Schistosoma japonicum. Parasitol Today (1998) 0.89
Molecular cloning and identification of a novel Clonorchis sinensis gene encoding a tegumental protein. Parasitol Res (2007) 0.87
Antigenicity and immunogenicity of the tegumental outer membrane of adult Schistosoma mansoni. Parasite Immunol (1985) 0.87
Vaccination against Schistosomiasis: The case for Lung-stage Antigens. Parasitol Today (1998) 0.85
Gene expression profiling for molecular staging and prognosis prediction in colorectal cancer. Expert Rev Mol Diagn (2004) 0.85
Release of leukotriene C4 (LTC4) from human eosinophils following adherence to IgE- and IgG-coated schistosomula of Schistosoma mansoni. Immunology (1990) 0.84
Sm22.6 antigen is an inhibitor to human thrombin. Mol Biochem Parasitol (2006) 0.83
The modulation of expression of polypeptide surface antigens on developing schistosomula of Schistosoma mansoni. J Immunol (1984) 0.83
Species-related innate resistance to Schistosoma mansoni. Role of mononuclear phagocytes in schistosomula killing in vitro. J Clin Invest (1983) 0.81
Schistosoma mansoni: activation of hemolytic activity in homogenates from live adult worms. Exp Parasitol (1986) 0.80
Immunolocalization of the fatty acid-binding protein Sj-FABPc within adult Schistosoma japonicum. Parasitology (1997) 0.79
Changes in the surface antigen profile of Schistosoma mansoni during maturation from cercaria to adult worm. Parasitology (1985) 0.78
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet (2006) 15.08
Schistosomiasis. N Engl J Med (2002) 7.48
Hookworm infection. N Engl J Med (2004) 4.58
Liver fluke induces cholangiocarcinoma. PLoS Med (2007) 3.89
Prevention and control of cystic echinococcosis. Lancet Infect Dis (2007) 3.64
Schistosomiasis elimination: lessons from the past guide the future. Lancet Infect Dis (2010) 3.63
Current status of vaccines for schistosomiasis. Clin Microbiol Rev (2008) 3.47
Whole-genome sequence of Schistosoma haematobium. Nat Genet (2012) 2.91
Enteropathogens and chronic illness in returning travelers. N Engl J Med (2013) 2.89
Concepts in immunology and diagnosis of hydatid disease. Clin Microbiol Rev (2003) 2.77
Katayama syndrome. Lancet Infect Dis (2007) 2.71
Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nat Med (2006) 2.59
Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Trop (2010) 2.23
New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum. PLoS Pathog (2006) 2.12
Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nat Rev Microbiol (2010) 2.10
Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource. Nat Genet (2003) 2.01
The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer. Trends Parasitol (2012) 1.86
Towards a taxonomic revision of the genus Echinococcus. Trends Parasitol (2002) 1.68
A drug-based intervention study on the importance of buffaloes for human Schistosoma japonicum infection around Poyang Lake, People's Republic of China. Am J Trop Med Hyg (2006) 1.67
Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria. J Immunol (2010) 1.65
DNA-based vaccines protect against zoonotic schistosomiasis in water buffalo. Vaccine (2008) 1.60
Diagnosis and management of schistosomiasis. BMJ (2011) 1.60
Vaccination of dogs against Echinococcus granulosus: a means to control hydatid disease? Trends Parasitol (2008) 1.58
Mathematical modelling of schistosomiasis japonica: comparison of control strategies in the People's Republic of China. Acta Trop (2002) 1.56
Developmental gene expression profiles of the human pathogen Schistosoma japonicum. BMC Genomics (2009) 1.56
Vaccines to combat the neglected tropical diseases. Immunol Rev (2011) 1.55
Trick or treat: the role of vaccines in integrated schistosomiasis control. PLoS Negl Trop Dis (2008) 1.54
Digestive proteases of blood-feeding nematodes. Trends Parasitol (2003) 1.48
Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini. PLoS Negl Trop Dis (2010) 1.46
Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. Int J Parasitol (2003) 1.46
A granulin-like growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, promotes proliferation of host cells. PLoS Pathog (2009) 1.45
Mitochondrial genomes of parasitic flatworms. Trends Parasitol (2002) 1.45
Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J (2005) 1.44
Zoonoses and marginalised infectious diseases of poverty: where do we stand? Parasit Vectors (2011) 1.44
The cytoskeleton and motor proteins of human schistosomes and their roles in surface maintenance and host-parasite interactions. Bioessays (2004) 1.42
Recent advances in the immunology and diagnosis of echinococcosis. FEMS Immunol Med Microbiol (2006) 1.42
A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J Biol Chem (2004) 1.41
X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J Mol Biol (2005) 1.40
Health-education package to prevent worm infections in Chinese schoolchildren. N Engl J Med (2013) 1.39
Clonorchis sinensis and Opisthorchis viverrini: development of a mitochondrial-based multiplex PCR for their identification and discrimination. Exp Parasitol (2005) 1.38
The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus. Genome Biol (2013) 1.37
Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6. Hepatology (2009) 1.37
Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini. BMC Genomics (2007) 1.35
The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini. Proteomics (2010) 1.35
Serological prevalence of echinococcosis and risk factors for infection among children in rural communities of southern Ningxia, China. Trop Med Int Health (2008) 1.35
A cluster-randomized bovine intervention trial against Schistosoma japonicum in the People's Republic of China: design and baseline results. Am J Trop Med Hyg (2007) 1.34
Discovery, structure and biological activities of the cyclotides. Curr Protein Pept Sci (2004) 1.33
Mechanisms of immunity in hydatid disease: implications for vaccine development. J Immunol (2008) 1.33
A cluster-randomised intervention trial against Schistosoma japonicum in the Peoples' Republic of China: bovine and human transmission. PLoS One (2009) 1.32
Transmission dynamics of Schistosoma japonicum in the lakes and marshlands of China. PLoS One (2008) 1.32
Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial. PLoS One (2011) 1.30
Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Rev Vaccines (2008) 1.30
The genome of the hydatid tapeworm Echinococcus granulosus. Nat Genet (2013) 1.29
A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility. PLoS Negl Trop Dis (2010) 1.28
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine (2005) 1.28
New technologies for the control of human hookworm infection. Trends Parasitol (2006) 1.27
Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum. Mol Cell Proteomics (2008) 1.26
Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover. PLoS Pathog (2010) 1.26
Community surveys and risk factor analysis of human alveolar and cystic echinococcosis in Ningxia Hui Autonomous Region, China. Bull World Health Organ (2006) 1.24
Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. J Infect Dis (2004) 1.24
Neglected tropical diseases of Oceania: review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis (2013) 1.23
Diagnosis of cystic echinococcosis, central Peruvian Highlands. Emerg Infect Dis (2008) 1.23
Large water management projects and schistosomiasis control, Dongting Lake region, China. Emerg Infect Dis (2007) 1.23
Immunology and immunodiagnosis of cystic echinococcosis: an update. Clin Dev Immunol (2011) 1.21
Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. FASEB J (2002) 1.20
Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3. J Invest Dermatol (2003) 1.19
Prevalence, intensity and associated morbidity of Schistosoma japonicum infection in the Dongting Lake region, China. Bull World Health Organ (2007) 1.19
A novel recombinant antigen for immunodiagnosis of human cystic echinococcosis. J Infect Dis (2003) 1.18
Temporal expression of chemokines dictates the hepatic inflammatory infiltrate in a murine model of schistosomiasis. PLoS Negl Trop Dis (2010) 1.18
Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infect Immun (2005) 1.18
Exposed proteins of the Schistosoma japonicum tegument. Int J Parasitol (2009) 1.18
A contributory role for activated hepatic stellate cells in the dynamics of Schistosoma japonicum egg-induced fibrosis. Int J Parasitol (2006) 1.17
Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice. Inflamm Bowel Dis (2009) 1.17
Transcriptomics tool for the human Schistosoma blood flukes using microarray gene expression profiling. Exp Parasitol (2006) 1.16
Tracking the fate of iron in early development of human blood flukes. Int J Biochem Cell Biol (2007) 1.14
Human fascioliasis and the presence of hybrid/introgressed forms of Fasciola hepatica and Fasciola gigantica in Vietnam. Int J Parasitol (2007) 1.14
Characterising the mucosal and systemic immune responses to experimental human hookworm infection. PLoS Pathog (2012) 1.13
Massively parallel sequencing and analysis of the Necator americanus transcriptome. PLoS Negl Trop Dis (2010) 1.12
A randomized, double-blind, placebo-controlled trial of safety and efficacy of combined praziquantel and artemether treatment for acute schistosomiasis japonica in China. Bull World Health Organ (2008) 1.11