PubRank

Yumiko Saga

Author PubWeight™ 101.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell 2007 3.74
2 Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice. Development 2007 3.06
3 Conserved role of nanos proteins in germ cell development. Science 2003 2.86
4 Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med 2008 2.68
5 Cell lineage in mammalian craniofacial mesenchyme. Mech Dev 2008 2.24
6 A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell 2012 2.08
7 The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 2005 1.94
8 The RNA-binding protein NANOS2 is required to maintain murine spermatogonial stem cells. Science 2009 1.65
9 Periostin is an extracellular matrix protein required for eruption of incisors in mice. Biochem Biophys Res Commun 2006 1.61
10 Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A 2007 1.60
11 Nanos2 suppresses meiosis and promotes male germ cell differentiation. Genes Dev 2008 1.55
12 Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system. Dev Biol 2005 1.42
13 The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3. Dev Biol 2009 1.41
14 Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development 2006 1.36
15 Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2. Development 2007 1.33
16 NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A 2010 1.32
17 Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites. Development 2003 1.32
18 Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells. Development 2012 1.29
19 Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling. Mech Dev 2004 1.27
20 Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression. Proc Natl Acad Sci U S A 2006 1.20
21 Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse. Development 2006 1.19
22 Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways. Dev Biol 2008 1.19
23 Notch signaling is required for the maintenance of enteric neural crest progenitors. Development 2008 1.17
24 Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers. Development 2011 1.16
25 The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice. Proc Natl Acad Sci U S A 2009 1.16
26 Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction. Circ Res 2004 1.16
27 Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One 2012 1.13
28 BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes Dev 2008 1.12
29 Mesp2 and Tbx6 cooperatively create periodic patterns coupled with the clock machinery during mouse somitogenesis. Development 2008 1.12
30 GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen. Genesis 2007 1.07
31 The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development 2007 1.05
32 Pofut1 is required for the proper localization of the Notch receptor during mouse development. Mech Dev 2008 1.04
33 Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency. Cardiovasc Res 2008 1.04
34 Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage. J Bone Miner Res 2004 1.03
35 Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2. Development 2006 1.02
36 Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation. Circ Res 2013 1.00
37 Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Proc Natl Acad Sci U S A 2012 1.00
38 Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression. Development 2012 1.00
39 Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome. Am J Hum Genet 2008 0.97
40 The protocadherin papc is involved in the organization of the epithelium along the segmental border during mouse somitogenesis. Dev Biol 2003 0.95
41 Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites. Development 2005 0.95
42 Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Dev Biol 2006 0.95
43 Frequent detection of noroviruses and sapoviruses in swine and high genetic diversity of porcine sapovirus in Japan during Fiscal Year 2008. J Clin Microbiol 2010 0.94
44 The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite. Development 2010 0.94
45 Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2. Development 2008 0.94
46 Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite. Dev Biol 2010 0.94
47 Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling. Nat Commun 2012 0.93
48 nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development. Mech Dev 2003 0.93
49 Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis. Dev Biol 2006 0.92
50 Notch signaling in Sertoli cells regulates cyclical gene expression of Hes1 but is dispensable for mouse spermatogenesis. Mol Cell Biol 2011 0.91
51 Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo. Development 2011 0.91
52 NANOS2 acts downstream of glial cell line-derived neurotrophic factor signaling to suppress differentiation of spermatogonial stem cells. Stem Cells 2012 0.91
53 Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. Mech Dev 2009 0.90
54 Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells. Development 2012 0.89
55 Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes. PLoS One 2011 0.89
56 The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis. Development 2010 0.88
57 Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology. Mech Dev 2008 0.87
58 The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse. Am J Physiol Lung Cell Mol Physiol 2013 0.87
59 Phenotypic analysis of a novel chordin mutant in medaka. Dev Dyn 2007 0.87
60 Penetration and differentiation of cephalic neural crest-derived cells in the developing mouse telencephalon. Dev Growth Differ 2012 0.87
61 Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. J Neurosci 2012 0.87
62 Specific gene silencing in the pre-implantation stage mouse embryo by an siRNA expression vector system. Mol Reprod Dev 2004 0.87
63 Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male. Biol Reprod 2012 0.87
64 Conditional gene targeting in mouse high endothelial venules. J Immunol 2009 0.86
65 Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res 2003 0.86
66 NANOS2 promotes male germ cell development independent of meiosis suppression. Dev Biol 2013 0.86
67 Implication of nanos2-3'UTR in the expression and function of nanos2. Mech Dev 2006 0.85
68 Ectopic retinoic acid signaling affects outflow tract cushion development through suppression of the myocardial Tbx2-Tgfβ2 pathway. Development 2012 0.85
69 Hesr1 knockout mice exhibit behavioral alterations through the dopaminergic nervous system. J Neurosci Res 2006 0.84
70 The CENP-O complex requirement varies among different cell types. Chromosome Res 2014 0.84
71 Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation. Dev Biol 2007 0.83
72 Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs. Carcinogenesis 2006 0.83
73 Induction of axon growth arrest without growth cone collapse through the N-terminal region of four-transmembrane glycoprotein M6a. Dev Neurobiol 2011 0.83
74 Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res 2004 0.82
75 Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction 2009 0.82
76 Hesr2 knockout mice develop aortic valve disease with advancing age. Arterioscler Thromb Vasc Biol 2013 0.82
77 Mesp1-nonexpressing cells contribute to the ventricular cardiac conduction system. Dev Dyn 2006 0.82
78 The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos. PLoS One 2010 0.81
79 Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis. Development 2002 0.81
80 Metameric pattern of intervertebral disc/vertebral body is generated independently of Mesp2/Ripply-mediated rostro-caudal patterning of somites in the mouse embryo. Dev Biol 2013 0.81
81 Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation. Dev Dyn 2007 0.81
82 Assessment of quantitative dual-parameter flow cytometric analysis for the evaluation of testicular toxicity using cyclophosphamide- and ethinylestradiol-treated rats. J Toxicol Sci 2002 0.80
83 TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis. Stem Cells Dev 2015 0.80
84 MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells. Stem Cells 2013 0.80
85 Mice stage-specific claudin 3 expression regulates progression of meiosis in early stage spermatocytes. Biol Reprod 2013 0.80
86 Transgenic analysis of the medaka mesp-b enhancer in somitogenesis. Dev Growth Differ 2006 0.80
87 Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone 2012 0.79
88 Expression and function of Sox21 during mouse cochlea development. Neurochem Res 2011 0.79
89 Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence. J Toxicol Sci 2012 0.79
90 Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. DNA Res 2002 0.78
91 Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod 2013 0.76
92 Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons. Dev Neurobiol 2012 0.76
93 Deletion of the Sox21 gene drastically affects hair lipids. Exp Dermatol 2012 0.75
94 [Sexual development of germ cells]. Tanpakushitsu Kakusan Koso 2007 0.75
95 Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res 2004 0.75