Published in Stem Cells on November 01, 2013
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Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis. J Clin Invest (2011) 1.37
Retinoic acid metabolism links the periodical differentiation of germ cells with the cycle of Sertoli cells in mouse seminiferous epithelium. Mech Dev (2011) 1.34
FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation. Development (2012) 1.22
Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways. Dev Biol (2008) 1.19
The spermatogonial stem cell niche. Microsc Res Tech (2009) 1.14
Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One (2012) 1.13
Distribution of GFRA1-expressing spermatogonia in adult mouse testis. Reproduction (2011) 1.07
Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation. Mol Cell Biol (2010) 1.07
Elucidating the identity and behavior of spermatogenic stem cells in the mouse testis. Reproduction (2012) 1.07
Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression. Development (2012) 1.00
Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, Sertoli cell proteins essential for spermatogonial stem cell maintenance. Exp Cell Res (2007) 0.99
Stage-specific changes in GDNF expression by rat Sertoli cells: a possible regulator of the replication and differentiation of stem spermatogonia. Biol Reprod (2011) 0.95
Notch signaling in Sertoli cells regulates cyclical gene expression of Hes1 but is dispensable for mouse spermatogenesis. Mol Cell Biol (2011) 0.91
Cyclical and patch-like GDNF distribution along the basal surface of Sertoli cells in mouse and hamster testes. PLoS One (2011) 0.91
NANOS2 acts downstream of glial cell line-derived neurotrophic factor signaling to suppress differentiation of spermatogonial stem cells. Stem Cells (2012) 0.91
The murine seminiferous epithelial cycle is pre-figured in the Sertoli cells of the embryonic testis. Development (2002) 0.86
Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia. Toxicology (2012) 0.84
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell (2007) 3.74
Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice. Development (2007) 3.06
Conserved role of nanos proteins in germ cell development. Science (2003) 2.86
Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med (2008) 2.68
Cell lineage in mammalian craniofacial mesenchyme. Mech Dev (2008) 2.24
A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell (2012) 2.08
The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature (2005) 1.94
The RNA-binding protein NANOS2 is required to maintain murine spermatogonial stem cells. Science (2009) 1.65
Periostin is an extracellular matrix protein required for eruption of incisors in mice. Biochem Biophys Res Commun (2006) 1.61
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.60
Nanos2 suppresses meiosis and promotes male germ cell differentiation. Genes Dev (2008) 1.55
MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells. Genes Dev (2011) 1.52
Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system. Dev Biol (2005) 1.42
The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3. Dev Biol (2009) 1.41
Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development (2006) 1.36
The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis. J Biol Chem (2012) 1.34
Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2. Development (2007) 1.33
NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A (2010) 1.32
Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites. Development (2003) 1.32
Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells. Development (2012) 1.29
Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling. Mech Dev (2004) 1.27
Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression. Proc Natl Acad Sci U S A (2006) 1.20
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse. Development (2006) 1.19
Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways. Dev Biol (2008) 1.19
Notch signaling is required for the maintenance of enteric neural crest progenitors. Development (2008) 1.17
Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers. Development (2011) 1.16
The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice. Proc Natl Acad Sci U S A (2009) 1.16
Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction. Circ Res (2004) 1.16
X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells. Hum Genet (2011) 1.14
RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids. Genes Dev (2012) 1.13
Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One (2012) 1.13
Mesp2 and Tbx6 cooperatively create periodic patterns coupled with the clock machinery during mouse somitogenesis. Development (2008) 1.12
BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes Dev (2008) 1.12
GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen. Genesis (2007) 1.07
Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways. Cell Mol Life Sci (2012) 1.06
The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development (2007) 1.05
Telomeric RNAs mark sex chromosomes in stem cells. Genetics (2009) 1.04
Pofut1 is required for the proper localization of the Notch receptor during mouse development. Mech Dev (2008) 1.04
Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency. Cardiovasc Res (2008) 1.04
Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage. J Bone Miner Res (2004) 1.03
Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2. Development (2006) 1.02
Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation. Circ Res (2013) 1.00
Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Proc Natl Acad Sci U S A (2012) 1.00
Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression. Development (2012) 1.00
Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects. PLoS One (2010) 0.98
Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome. Am J Hum Genet (2008) 0.97
Human postmeiotic sex chromatin and its impact on sex chromosome evolution. Genome Res (2012) 0.97
The protocadherin papc is involved in the organization of the epithelium along the segmental border during mouse somitogenesis. Dev Biol (2003) 0.95
Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites. Development (2005) 0.95
A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis. PLoS Genet (2007) 0.95
Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Dev Biol (2006) 0.95
Frequent detection of noroviruses and sapoviruses in swine and high genetic diversity of porcine sapovirus in Japan during Fiscal Year 2008. J Clin Microbiol (2010) 0.94
The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite. Development (2010) 0.94
Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite. Dev Biol (2010) 0.94
Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2. Development (2008) 0.94
Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling. Nat Commun (2012) 0.93
nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development. Mech Dev (2003) 0.93
Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis. Dev Biol (2006) 0.92
Notch signaling in Sertoli cells regulates cyclical gene expression of Hes1 but is dispensable for mouse spermatogenesis. Mol Cell Biol (2011) 0.91
Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo. Development (2011) 0.91
NANOS2 acts downstream of glial cell line-derived neurotrophic factor signaling to suppress differentiation of spermatogonial stem cells. Stem Cells (2012) 0.91
Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. Mech Dev (2009) 0.90
Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells. Development (2012) 0.89
Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes. PLoS One (2011) 0.89
The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis. Development (2010) 0.88
Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology. Mech Dev (2008) 0.87
Penetration and differentiation of cephalic neural crest-derived cells in the developing mouse telencephalon. Dev Growth Differ (2012) 0.87
Specific gene silencing in the pre-implantation stage mouse embryo by an siRNA expression vector system. Mol Reprod Dev (2004) 0.87
Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. J Neurosci (2012) 0.87
The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse. Am J Physiol Lung Cell Mol Physiol (2013) 0.87
Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male. Biol Reprod (2012) 0.87
Phenotypic analysis of a novel chordin mutant in medaka. Dev Dyn (2007) 0.87
Conditional gene targeting in mouse high endothelial venules. J Immunol (2009) 0.86
NANOS2 promotes male germ cell development independent of meiosis suppression. Dev Biol (2013) 0.86
Implication of nanos2-3'UTR in the expression and function of nanos2. Mech Dev (2006) 0.85
Ectopic retinoic acid signaling affects outflow tract cushion development through suppression of the myocardial Tbx2-Tgfβ2 pathway. Development (2012) 0.85
Hesr1 knockout mice exhibit behavioral alterations through the dopaminergic nervous system. J Neurosci Res (2006) 0.84
The CENP-O complex requirement varies among different cell types. Chromosome Res (2014) 0.84
Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation. Dev Biol (2007) 0.83
Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs. Carcinogenesis (2006) 0.83
Induction of axon growth arrest without growth cone collapse through the N-terminal region of four-transmembrane glycoprotein M6a. Dev Neurobiol (2011) 0.83
DNA topoisomerase II interacts with Lim15/Dmc1 in meiosis. Nucleic Acids Res (2005) 0.82
Hesr2 knockout mice develop aortic valve disease with advancing age. Arterioscler Thromb Vasc Biol (2013) 0.82
Mesp1-nonexpressing cells contribute to the ventricular cardiac conduction system. Dev Dyn (2006) 0.82
Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction (2009) 0.82
Sumoylation of a meiosis-specific RecA homolog, Lim15/Dmc1, via interaction with the small ubiquitin-related modifier (SUMO)-conjugating enzyme Ubc9. FEBS J (2006) 0.81
The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos. PLoS One (2010) 0.81
Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation. Dev Dyn (2007) 0.81
Metameric pattern of intervertebral disc/vertebral body is generated independently of Mesp2/Ripply-mediated rostro-caudal patterning of somites in the mouse embryo. Dev Biol (2013) 0.81
Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis. Development (2002) 0.81
Assessment of quantitative dual-parameter flow cytometric analysis for the evaluation of testicular toxicity using cyclophosphamide- and ethinylestradiol-treated rats. J Toxicol Sci (2002) 0.80
Transgenic analysis of the medaka mesp-b enhancer in somitogenesis. Dev Growth Differ (2006) 0.80
TALEN-Mediated Gene Disruption on Y Chromosome Reveals Critical Role of EIF2S3Y in Mouse Spermatogenesis. Stem Cells Dev (2015) 0.80
Mice stage-specific claudin 3 expression regulates progression of meiosis in early stage spermatocytes. Biol Reprod (2013) 0.80
Expression and function of Sox21 during mouse cochlea development. Neurochem Res (2011) 0.79
The great escape: Active genes on inactive sex chromosomes and their evolutionary implications. Epigenetics (2013) 0.79
Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence. J Toxicol Sci (2012) 0.79
Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone (2012) 0.79