Published in J Alzheimers Dis on January 01, 2010
Chromosomal aneuploidy in the aging brain. Mech Ageing Dev (2011) 0.95
Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis (2011) 0.90
The pathological roles of ganglioside metabolism in Alzheimer's disease: effects of gangliosides on neurogenesis. Int J Alzheimers Dis (2011) 0.83
Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance. PLoS One (2012) 0.80
Cognitive deficits and disruption of neurogenesis in a mouse model of apolipoprotein E4 domain interaction. J Biol Chem (2013) 0.78
DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres. J Neurosci Res (2011) 0.78
Cux2 activity defines a subpopulation of perinatal neurogenic progenitors in the hippocampus. Hippocampus (2014) 0.77
The role of cognitive activity in cognition protection: from Bedside to Bench. Transl Neurodegener (2017) 0.75
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc Natl Acad Sci U S A (2007) 4.69
Regulatory roles of natural antisense transcripts. Nat Rev Mol Cell Biol (2009) 4.48
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A (2002) 4.20
Complex Loci in human and mouse genomes. PLoS Genet (2006) 3.74
The reality of pervasive transcription. PLoS Biol (2011) 3.41
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol (2012) 3.07
RNAdb--a comprehensive mammalian noncoding RNA database. Nucleic Acids Res (2005) 2.84
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
Striatal microRNA controls cocaine intake through CREB signalling. Nature (2010) 2.56
A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Res (2005) 2.27
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Res (2005) 2.20
Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biol (2010) 2.08
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00
Considerations when using the significance analysis of microarrays (SAM) algorithm. BMC Bioinformatics (2005) 1.89
Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy. FASEB J (2005) 1.85
A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol (2008) 1.80
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Sci Transl Med (2013) 1.74
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes. Genome Med (2010) 1.64
Improved and automated prediction of effective siRNA. Biochem Biophys Res Commun (2004) 1.58
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One (2008) 1.57
MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proc Natl Acad Sci U S A (2012) 1.49
Pseudo-messenger RNA: phantoms of the transcriptome. PLoS Genet (2006) 1.46
Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends Genet (2012) 1.46
Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians. Diabetes (2004) 1.41
MicroRNA dysregulation in psychiatric disease. Brain Res (2010) 1.34
Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Res (2006) 1.27
Noncoding RNAs: couplers of analog and digital information in nervous system function? Trends Neurosci (2007) 1.27
Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells. BMC Genomics (2012) 1.26
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease. J Neuroinflammation (2010) 1.25
RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals. Genome Biol (2006) 1.21
Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? FASEB J (2007) 1.19
Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes. Genomics (2005) 1.18
microRNAs in CNS disorders. Neuromolecular Med (2009) 1.17
Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Res (2008) 1.14
Validating siRNA using a reporter made from synthetic DNA oligonucleotides. Biochem Biophys Res Commun (2004) 1.14
Therapeutic potential of neuropeptide Y (NPY) receptor ligands. EMBO Mol Med (2010) 1.12
Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability. Circulation (2003) 1.10
NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes. Proc Natl Acad Sci U S A (2002) 1.10
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. BMC Genomics (2007) 1.10
Personalized medicine in psychiatry: problems and promises. BMC Med (2013) 1.09
Activity-induced and developmental downregulation of the Nogo receptor. Cell Tissue Res (2003) 1.07
Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model. Cancer Res (2004) 1.07
Identification of functional SNPs in the 5-prime flanking sequences of human genes. BMC Genomics (2005) 1.07
Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs. Biochem Biophys Res Commun (2003) 1.06
A new approach to genome mapping and sequencing: slalom libraries. Nucleic Acids Res (2002) 1.05
Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism. J Psychiatr Res (2004) 1.04
Involvement of long noncoding RNAs in diseases affecting the central nervous system. RNA Biol (2012) 1.04
The expression signature of in vitro senescence resembles mouse but not human aging. Genome Biol (2005) 1.03
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression. Blood (2013) 1.03
Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening. Mol Pharmacol (2009) 0.98
Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease. Neurosci Lett (2009) 0.96
hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein. Gene (2002) 0.96
Epigenetic mechanisms of gene regulation during mammalian spermatogenesis. Epigenetics (2008) 0.95
RNA Interference with chemically modified siRNA. Curr Top Med Chem (2006) 0.93
Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function. Regul Pept (2005) 0.93
No induction of anti-viral responses in human cell lines HeLa and MCF-7 when transfecting with siRNA or siLNA. Biochem Biophys Res Commun (2006) 0.93
Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication. FEBS Lett (2004) 0.92
GeneLynx mouse: integrated portal to the mouse genome. Genome Res (2003) 0.92
NotI flanking sequences: a tool for gene discovery and verification of the human genome. Nucleic Acids Res (2002) 0.92
Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence. Addict Biol (2008) 0.91
A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. Alcohol Clin Exp Res (2005) 0.91
NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations. Alcohol Clin Exp Res (2003) 0.90
Functional comparison of single- and double-stranded siRNAs in mammalian cells. Biochem Biophys Res Commun (2004) 0.90
mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides. Nucleic Acids Res (2003) 0.90
Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis (2011) 0.90
The Emerging Role of Non-Coding RNAs in Drug Addiction. Front Genet (2012) 0.89
The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. Curr Alzheimer Res (2016) 0.89
A universal plasmid library encoding all permutations of small interfering RNA. Proc Natl Acad Sci U S A (2005) 0.89
Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin. Hum Genet (2005) 0.89
Genetics of neurological disorders. Expert Rev Mol Diagn (2004) 0.88
Gene characterization index: assessing the depth of gene annotation. PLoS One (2008) 0.86
RNAi screen indicates widespread biological function for human natural antisense transcripts. PLoS One (2010) 0.86
Role of Sirtuin 1 in metabolic regulation. Drug Discov Today (2010) 0.85
Characterization of RNA interference in rat PC12 cells: requirement of GERp95. Biochem Biophys Res Commun (2004) 0.85
Epigenetic pathways and glioblastoma treatment. Epigenetics (2013) 0.85
Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties. Regul Pept (2003) 0.84
Focusing on RISC assembly in mammalian cells. Biochem Biophys Res Commun (2008) 0.83
Navigating genomic maps of cancer cells. Nat Biotechnol (2010) 0.82
Nonsynonymous SNPs: validation characteristics, derived allele frequency patterns, and suggestive evidence for natural selection. Hum Mutat (2006) 0.82
Transcriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs. Breast Cancer Res Treat (2014) 0.80
Anti-cataleptic effects of clozapine, but not olanzapine and quetiapine, on SCH 23390- or raclopride-induced catalepsy in rats. Eur Neuropsychopharmacol (2003) 0.79
Functional interactions between delta- and mu-opioid receptors in rat thermoregulation. Eur J Pharmacol (2003) 0.79
Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides. Nucleic Acids Res (2002) 0.78
Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg Med Chem Lett (2012) 0.77
Analysis of 5-hydroxytryptamine 2c receptor gene promoter variants as alcohol-dependence risk factors. Alcohol Alcohol (2004) 0.76
Oligonucleotides for upregulating gene expression. Pharm Pat Anal (2013) 0.76
Vector-based siRNA delivery strategies for high-throughput screening of novel target genes. J RNAi Gene Silencing (2005) 0.76
Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein. Biochem Biophys Res Commun (2005) 0.76
Extracellular Uridine Triphosphate and Adenosine Triphosphate Attenuate Endothelial Inflammation through miR-22-Mediated ICAM-1 Inhibition. J Vasc Res (2015) 0.76
RNA mechanisms in CNS systems and disorders. Brain Res (2010) 0.75
RNAi joins the "Singles Club". Mol Ther (2012) 0.75
Exploring the foundation of genomics: a northern blot reference set for the comparative analysis of transcript profiling technologies. Comp Funct Genomics (2004) 0.75
How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications. Brief Bioinform (2017) 0.75
How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications. Brief Bioinform (2016) 0.75
Antisense-induced Fas mRNA degradation produces site-specific stable 3'-mRNA fragment by exonuclease cleavage at the complementary sequence. Oligonucleotides (2004) 0.75