Published in Nat Biotechnol on March 25, 2012
Long noncoding RNAs: cellular address codes in development and disease. Cell (2013) 6.01
MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat Rev Drug Discov (2013) 3.33
Gene regulation by antisense transcription. Nat Rev Genet (2013) 1.90
Targeting long non-coding RNA to therapeutically upregulate gene expression. Nat Rev Drug Discov (2013) 1.82
Evolutionary conservation of long non-coding RNAs; sequence, structure, function. Biochim Biophys Acta (2013) 1.79
Cis-acting noncoding RNAs: friends and foes. Nat Struct Mol Biol (2012) 1.73
Long noncoding RNAs: fresh perspectives into the RNA world. Trends Biochem Sci (2013) 1.55
Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends Genet (2012) 1.46
Regulation of transcription by long noncoding RNAs. Annu Rev Genet (2014) 1.43
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets. Mol Cell Ther (2015) 1.32
MYC regulates the non-coding transcriptome. Oncotarget (2014) 1.29
Promoter RNA links transcriptional regulation of inflammatory pathway genes. Nucleic Acids Res (2013) 1.24
The complex transcriptional landscape of the anucleate human platelet. BMC Genomics (2013) 1.23
MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures. Nat Commun (2015) 1.15
Activity-dependent human brain coding/noncoding gene regulatory networks. Genetics (2012) 1.13
Physiological roles of long noncoding RNAs: insight from knockout mice. Trends Cell Biol (2014) 1.12
Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease. Front Genet (2014) 1.11
An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription. Mol Ther (2014) 1.11
Regulation of the apolipoprotein gene cluster by a long noncoding RNA. Cell Rep (2014) 1.10
Antisense oligonucleotides: treating neurodegeneration at the level of RNA. Neurotherapeutics (2013) 1.10
Non-coding RNAs as direct and indirect modulators of epigenetic regulation. Epigenetics (2014) 1.09
Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs. Epigenetics (2013) 1.08
The MicroRNA Biology of the Mammalian Nucleus. Mol Ther Nucleic Acids (2014) 1.05
Involvement of long noncoding RNAs in diseases affecting the central nervous system. RNA Biol (2012) 1.04
Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy. Neurotherapeutics (2013) 1.02
Brain-Derived Neurotrophic Factor Expression in Asthma. Association with Severity and Type 2 Inflammatory Processes. Am J Respir Cell Mol Biol (2015) 1.02
The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease. Philos Trans R Soc Lond B Biol Sci (2014) 1.01
Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data. Genome Res (2013) 0.99
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides. Nucleic Acids Res (2015) 0.99
Long non-coding RNA targeting and transcriptional de-repression. Nucleic Acid Ther (2013) 0.98
From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease. Endocr Rev (2014) 0.98
Natural antisense transcripts. Hum Mol Genet (2014) 0.94
Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes. Elife (2014) 0.93
RNA-mediated gene activation. Epigenetics (2013) 0.92
The emerging role of pseudogene expressed non-coding RNAs in cellular functions. Int J Biochem Cell Biol (2014) 0.92
Emerging epigenetic mechanisms of long non-coding RNAs. Neuroscience (2013) 0.91
Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer. Genomics Proteomics Bioinformatics (2016) 0.91
The landscape of antisense gene expression in human cancers. Genome Res (2015) 0.91
The anti-inflammatory effects of flavanol-rich lychee fruit extract in rat hepatocytes. PLoS One (2014) 0.91
Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and function. Neuroscience (2013) 0.89
The Emerging Role of Non-Coding RNAs in Drug Addiction. Front Genet (2012) 0.89
Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders. Front Genet (2012) 0.89
Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders. Mol Autism (2013) 0.88
Basic biology and therapeutic implications of lncRNA. Adv Drug Deliv Rev (2015) 0.88
SINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells. Front Cell Neurosci (2015) 0.88
Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA. BMC Genomics (2015) 0.87
Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma. Pharmacol Ther (2016) 0.87
The functions of natural antisense transcripts. Essays Biochem (2013) 0.86
Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility. Front Genet (2014) 0.86
Sense-antisense gene pairs: sequence, transcription, and structure are not conserved between human and mouse. Front Genet (2013) 0.85
Epigenetics and ncRNAs in brain function and disease: mechanisms and prospects for therapy. Neurotherapeutics (2013) 0.85
De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics. Mol Ther Nucleic Acids (2014) 0.83
Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells. Mol Ther Nucleic Acids (2012) 0.82
Asymmetric localization of natural antisense RNA of neuropeptide sensorin in Aplysia sensory neurons during aging and activity. Front Genet (2014) 0.82
Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice. PLoS One (2014) 0.82
Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis. Sci Rep (2015) 0.82
Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression. Oncotarget (2014) 0.82
Identification of a functionally distinct truncated BDNF mRNA splice variant and protein in Trachemys scripta elegans. PLoS One (2013) 0.82
Epigenetic regulation of the neural transcriptome and alcohol interference during development. Front Genet (2014) 0.82
Antisense RNA controls LRP1 Sense transcript expression through interaction with a chromatin-associated protein, HMGB2. Cell Rep (2015) 0.82
Transcriptional gene silencing in humans. Nucleic Acids Res (2016) 0.82
MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions. Int J Mol Sci (2016) 0.82
Small and Long Non-Coding RNAs: Novel Targets in Perspective Cancer Therapy. Curr Genomics (2015) 0.81
Relationship of Focally Amplified Long Noncoding on Chromosome 1 (FAL1) lncRNA with E2F Transcription Factors in Thyroid Cancer. Medicine (Baltimore) (2016) 0.81
Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease. Mol Psychiatry (2015) 0.81
Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen. J Biomol Screen (2015) 0.81
A three-way parallel ICA approach to analyze links among genetics, brain structure and brain function. Neuroimage (2014) 0.81
Association of genetic variation in pharmacodynamic factors with methadone dose required for effective treatment of opioid addiction. Pharmacogenomics (2013) 0.80
Not so pseudo anymore: pseudogenes as therapeutic targets. Pharmacogenomics (2013) 0.80
Epigenetics of Alzheimer's disease and frontotemporal dementia. Neurotherapeutics (2013) 0.80
Noncoding RNAs and pancreatic cancer. World J Gastroenterol (2016) 0.79
Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction. Epigenomics (2015) 0.79
A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells. Mol Ther Nucleic Acids (2013) 0.79
MYCNOS functions as an antisense RNA regulating MYCN. RNA Biol (2015) 0.79
Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease. PLoS One (2016) 0.79
RNAe: an effective method for targeted protein translation enhancement by artificial non-coding RNA with SINEB2 repeat. Nucleic Acids Res (2015) 0.79
Small and Long Regulatory RNAs in the Immune System and Immune Diseases. Front Immunol (2014) 0.79
Emerging landscape of non-coding RNAs in oral health and disease. Oral Dis (2013) 0.78
Splicing of a non-coding antisense transcript controls LEF1 gene expression. Nucleic Acids Res (2015) 0.78
Developing epigenetic diagnostics and therapeutics for brain disorders. Trends Mol Med (2013) 0.78
AntagoNATs boost gene expression. Nat Methods (2012) 0.78
Long non-coding RNAs in corticogenesis: deciphering the non-coding code of the brain. EMBO J (2015) 0.78
Genetic and epigenetic regulation of the brain-derived neurotrophic factor in the central nervous system. Yale J Biol Med (2014) 0.78
Non-coding RNA regulation of synaptic plasticity and memory: implications for aging. Ageing Res Rev (2014) 0.78
Non-coding RNA LINC00857 is predictive of poor patient survival and promotes tumor progression via cell cycle regulation in lung cancer. Oncotarget (2016) 0.78
The chemical evolution of oligonucleotide therapies of clinical utility. Nat Biotechnol (2017) 0.77
Circadian rhythms of sense and antisense transcription in sugarcane, a highly polyploid crop. PLoS One (2013) 0.77
Natural antisense transcripts as therapeutic targets. Drug Discov Today Ther Strateg (2013) 0.77
Pathways to smoking behaviours: biological insights from the Tobacco and Genetics Consortium meta-analysis. Mol Psychiatry (2016) 0.77
LncRNA BCAR4 wires up signaling transduction in breast cancer. RNA Biol (2015) 0.77
Associating schizophrenia, long non-coding RNAs and neurostructural dynamics. Front Mol Neurosci (2015) 0.77
RaNA therapeutics. Nat Biotechnol (2012) 0.77
Chromatin-bound RNA and the neurobiology of psychiatric disease. Neuroscience (2013) 0.77
Non-Coding RNAs as Potential Neuroprotectants against Ischemic Brain Injury. Brain Sci (2013) 0.77
EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia. Mol Ther (2014) 0.77
Identification of long noncoding RNAs dysregulated in the midbrain of human cocaine abusers. J Neurochem (2015) 0.77
Emerging bioinformatics approaches for analysis of NGS-derived coding and non-coding RNAs in neurodegenerative diseases. Front Cell Neurosci (2014) 0.76
Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome. EBioMedicine (2016) 0.76
Preparation of 5'-O-(1-Thiotriphosphate)-modified oligonucleotides using polymerase-endonuclease amplification reaction (PEAR). PLoS One (2013) 0.76
Long noncoding RNAs in psychiatric disorders. Psychiatr Genet (2016) 0.76
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Non-coding RNA. Hum Mol Genet (2006) 10.57
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature (2008) 10.11
Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Cell (2010) 9.50
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature (2008) 7.64
Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci U S A (2008) 7.19
Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell (2010) 6.88
The antisense transcriptomes of human cells. Science (2008) 6.29
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat Chem Biol (2007) 5.05
Regulatory roles of natural antisense transcripts. Nat Rev Mol Cell Biol (2009) 4.48
Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet (2008) 4.45
Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. Mol Cell (2005) 4.07
Polycomb complexes and epigenetic states. Curr Opin Cell Biol (2008) 3.81
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci (2007) 3.81
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO J (2010) 3.18
Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc Natl Acad Sci U S A (2000) 3.04
Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics (2007) 2.89
Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res (2005) 2.34
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. J Clin Invest (2010) 2.29
Non-coding RNAs in the nervous system. J Physiol (2006) 1.87
Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5. Transcription (2010) 1.85
Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome. J Neurosci (2007) 1.85
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci U S A (2010) 1.72
Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells. Epigenetics (2009) 1.71
Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth. Proc Natl Acad Sci U S A (2009) 1.67
Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain Stimul (2010) 1.57
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One (2008) 1.57
Neurogenic effect of beta-amyloid peptide in the development of neural stem cells. J Neurosci (2004) 1.54
A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neurosci Lett (2010) 1.36
Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus. PLoS One (2010) 1.30
Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients. Int J Neuropsychopharmacol (2010) 1.21
MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production. Epigenetics (2007) 1.20
Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway. Brain Behav Immun (2010) 1.14
Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism. J Neurodev Disord (2009) 1.10
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. BMC Genomics (2007) 1.10
Brain-derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived dopamine progenitors to functional neurons. J Neurochem (2009) 1.01
BDNF/MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration. Cereb Cortex (2009) 1.00
Differential regulation of neurotrophin S100B and BDNF in two rat models of depression. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.99
Neurotrophins enhance CaMKII activity and rescue amyloid-β-induced deficits in hippocampal synaptic plasticity. J Alzheimers Dis (2010) 0.99
Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters. Nucleic Acids Res (2010) 0.97
Association of the brain-derived neurotrophic factor Val66Met polymorphism with hippocampus volumes in drug-free depressed patients. World J Biol Psychiatry (2010) 0.96
Induction of striatal neurogenesis enhances functional recovery in an adult animal model of neonatal hypoxic-ischemic brain injury. Neuroscience (2010) 0.96
A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR). Cell Cycle (2010) 0.93
Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients. Neuropsychobiology (2010) 0.93
A role for MAPK and PI-3K signaling pathways in brain-derived neurotrophic factor modification of conditioned taste aversion retention. Behav Brain Res (2010) 0.87
Synaptic maturation of the Xenopus retinotectal system: effects of brain-derived neurotrophic factor on synapse ultrastructure. J Comp Neurol (2010) 0.86
Differentiation/maturation of neuropeptide Y neurons in the corpus callosum is promoted by brain-derived neurotrophic factor in mouse brain slice cultures. Neurosci Lett (2008) 0.81
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol Dis (2006) 5.96
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc Natl Acad Sci U S A (2007) 4.69
Regulatory roles of natural antisense transcripts. Nat Rev Mol Cell Biol (2009) 4.48
Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A (2002) 4.20
Complex Loci in human and mouse genomes. PLoS Genet (2006) 3.74
The reality of pervasive transcription. PLoS Biol (2011) 3.41
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat Genet (2011) 2.97
RNAdb--a comprehensive mammalian noncoding RNA database. Nucleic Acids Res (2005) 2.84
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
Striatal microRNA controls cocaine intake through CREB signalling. Nature (2010) 2.56
A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Res (2005) 2.27
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Res (2005) 2.20
Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biol (2010) 2.08
Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease. Traffic (2004) 2.05
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00
Considerations when using the significance analysis of microarrays (SAM) algorithm. BMC Bioinformatics (2005) 1.89
Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy. FASEB J (2005) 1.85
A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol (2008) 1.80
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Sci Transl Med (2013) 1.74
Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1. J Neurochem (2007) 1.70
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes. Genome Med (2010) 1.64
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations. Sci Transl Med (2012) 1.62
Improved and automated prediction of effective siRNA. Biochem Biophys Res Commun (2004) 1.58
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One (2008) 1.57
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells. EMBO J (2009) 1.55
MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proc Natl Acad Sci U S A (2012) 1.49
Pseudo-messenger RNA: phantoms of the transcriptome. PLoS Genet (2006) 1.46
Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends Genet (2012) 1.46
Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians. Diabetes (2004) 1.41
MicroRNA dysregulation in psychiatric disease. Brain Res (2010) 1.34
Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Res (2006) 1.27
Noncoding RNAs: couplers of analog and digital information in nervous system function? Trends Neurosci (2007) 1.27
Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells. BMC Genomics (2012) 1.26
Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment. Cell (2010) 1.25
RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals. Genome Biol (2006) 1.21
Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? FASEB J (2007) 1.19
Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization. Brain Res Mol Brain Res (2005) 1.18
Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes. Genomics (2005) 1.18
Regulation of G protein-coupled receptor trafficking by inefficient plasma membrane expression: molecular basis of an evolved strategy. J Biol Chem (2006) 1.17
microRNAs in CNS disorders. Neuromolecular Med (2009) 1.17
Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Res (2008) 1.14
Validating siRNA using a reporter made from synthetic DNA oligonucleotides. Biochem Biophys Res Commun (2004) 1.14
Protein folding as posttranslational regulation: evolution of a mechanism for controlled plasma membrane expression of a G protein-coupled receptor. Mol Endocrinol (2006) 1.14
Kinesin-associated protein 3 (KIFAP3) has no effect on survival in a population-based cohort of ALS patients. Proc Natl Acad Sci U S A (2010) 1.13
Therapeutic potential of neuropeptide Y (NPY) receptor ligands. EMBO Mol Med (2010) 1.12
NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes. Proc Natl Acad Sci U S A (2002) 1.10
Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability. Circulation (2003) 1.10
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. BMC Genomics (2007) 1.10
Personalized medicine in psychiatry: problems and promises. BMC Med (2013) 1.09
Refolding of misfolded mutant GPCR: post-translational pharmacoperone action in vitro. Mol Cell Endocrinol (2007) 1.08
Activity-induced and developmental downregulation of the Nogo receptor. Cell Tissue Res (2003) 1.07
Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model. Cancer Res (2004) 1.07
Parallel regulation of membrane trafficking and dominant-negative effects by misrouted gonadotropin-releasing hormone receptor mutants. J Biol Chem (2005) 1.07
Identification of functional SNPs in the 5-prime flanking sequences of human genes. BMC Genomics (2005) 1.07
Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs. Biochem Biophys Res Commun (2003) 1.06
A new approach to genome mapping and sequencing: slalom libraries. Nucleic Acids Res (2002) 1.05
Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism. J Psychiatr Res (2004) 1.04
Involvement of long noncoding RNAs in diseases affecting the central nervous system. RNA Biol (2012) 1.04
The expression signature of in vitro senescence resembles mouse but not human aging. Genome Biol (2005) 1.03
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression. Blood (2013) 1.03
Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening. Mol Pharmacol (2009) 0.98
Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer. PLoS One (2012) 0.97
Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease. Neurosci Lett (2009) 0.96
hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein. Gene (2002) 0.96
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue. PLoS One (2011) 0.96
Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease. Neurosci Lett (2009) 0.96
Epigenetic mechanisms of gene regulation during mammalian spermatogenesis. Epigenetics (2008) 0.95
Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function. Regul Pept (2005) 0.93
RNA Interference with chemically modified siRNA. Curr Top Med Chem (2006) 0.93
No induction of anti-viral responses in human cell lines HeLa and MCF-7 when transfecting with siRNA or siLNA. Biochem Biophys Res Commun (2006) 0.93
Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication. FEBS Lett (2004) 0.92
GeneLynx mouse: integrated portal to the mouse genome. Genome Res (2003) 0.92
NotI flanking sequences: a tool for gene discovery and verification of the human genome. Nucleic Acids Res (2002) 0.92
Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence. Addict Biol (2008) 0.91
'Effective inefficiency': cellular control of protein trafficking as a mechanism of post-translational regulation. J Endocrinol (2006) 0.91
A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. Alcohol Clin Exp Res (2005) 0.91
NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations. Alcohol Clin Exp Res (2003) 0.90
Functional comparison of single- and double-stranded siRNAs in mammalian cells. Biochem Biophys Res Commun (2004) 0.90
mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides. Nucleic Acids Res (2003) 0.90
Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis (2011) 0.90
The Emerging Role of Non-Coding RNAs in Drug Addiction. Front Genet (2012) 0.89
A universal plasmid library encoding all permutations of small interfering RNA. Proc Natl Acad Sci U S A (2005) 0.89
The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. Curr Alzheimer Res (2016) 0.89
Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin. Hum Genet (2005) 0.89
Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders. Mol Autism (2013) 0.88