PubRank

Fang-Rong Chang

Author PubWeight™ 102.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A new anti-HIV alkaloid, drymaritin, and a new C-glycoside flavonoid, diandraflavone, from Drymaria diandra. J Nat Prod 2004 1.42
2 Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents. J Med Chem 2006 1.25
3 Synthesis of chalcone derivatives as potential anti-diabetic agents. Bioorg Med Chem Lett 2012 1.25
4 Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves. Molecules 2009 1.23
5 Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell Int 2013 1.19
6 Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells. Cancer Lett 2009 1.18
7 Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress. BMC Complement Altern Med 2012 1.12
8 Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria. Mol Cancer Ther 2005 1.11
9 Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis. Food Chem Toxicol 2012 1.10
10 Recent research and development of Antrodia cinnamomea. Pharmacol Ther 2013 1.09
11 Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics. PLoS Comput Biol 2011 1.08
12 Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida. J Nat Prod 2009 1.06
13 4beta-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. BMC Cancer 2010 1.06
14 Acetogenins as selective inhibitors of the human ovarian 1A9 tumor cell line. J Med Chem 2003 1.05
15 Antiproliferation and induction of apoptosis in Ca9-22 oral cancer cells by ethanolic extract of Gracilaria tenuistipitata. Molecules 2012 1.05
16 Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. Mutat Res 2012 1.03
17 New ent-kaurane diterpenoids with anti-platelet aggregation activity from Annona squamosa. J Nat Prod 2002 1.00
18 Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. J Agric Food Chem 2011 1.00
19 Inhibitory effects of 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose on biofilm formation by Staphylococcus aureus. Antimicrob Agents Chemother 2010 0.99
20 Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299. DNA Cell Biol 2009 0.97
21 An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii. Bioorg Med Chem 2013 0.97
22 Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins. J Biol Chem 2008 0.97
23 Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2. Antiviral Res 2010 0.97
24 New cytotoxic flavonoids from Thelypteris torresiana. Planta Med 2005 0.96
25 First total synthesis of protoapigenone and its analogues as potent cytotoxic agents. J Med Chem 2007 0.96
26 Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis. Bioorg Med Chem Lett 2008 0.95
27 New cytotoxic cyclic peptides and dianthramide from Dianthus superbus. J Nat Prod 2004 0.95
28 Historic perspectives on Annonaceous acetogenins from the chemical bench to preclinical trials. Planta Med 2010 0.93
29 Molluscicidal saponins from Sapindus mukorossi, inhibitory agents of golden apple snails, Pomacea canaliculata. J Agric Food Chem 2003 0.93
30 Antitumor agents. 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents. Bioorg Med Chem Lett 2009 0.93
31 Inhibitory effects of 16-hydroxycleroda-3,13(14)E-dien-15-oic acid on superoxide anion and elastase release in human neutrophils through multiple mechanisms. Eur J Pharmacol 2008 0.92
32 New cembranolide analogues from the formosan soft coral Sinularia flexibilis and their cytotoxicity. Nat Prod Res 2003 0.92
33 Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. PLoS One 2013 0.92
34 Withanolides-induced breast cancer cell death is correlated with their ability to inhibit heat protein 90. PLoS One 2012 0.92
35 New cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona muricata. J Nat Prod 2002 0.91
36 Cytotoxic withanolides from Tubocapsicum anomalum. J Nat Prod 2007 0.90
37 An aluminum microfluidic chip fabrication using a convenient micromilling process for fluorescent poly(DL-lactide-co-glycolide) microparticle generation. Sensors (Basel) 2012 0.89
38 A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression. Mol Cancer Ther 2007 0.88
39 Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana. Z Naturforsch C 2003 0.88
40 Selective targeting of breast cancer cells through ROS-mediated mechanisms potentiates the lethality of paclitaxel by a novel diterpene, gelomulide K. Free Radic Biol Med 2011 0.88
41 Aqueous extract of the edible Gracilaria tenuistipitata inhibits hepatitis C viral replication via cyclooxygenase-2 suppression and reduces virus-induced inflammation. PLoS One 2013 0.88
42 Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells. Eur J Pharmacol 2005 0.87
43 New cytotoxic lupane triterpenes from Perrottetia arisanensis. Planta Med 2009 0.87
44 Norcantharidin induces apoptosis of breast cancer cells: involvement of activities of mitogen activated protein kinases and signal transducers and activators of transcription. Toxicol In Vitro 2011 0.87
45 CD36 is a novel and potential anti-fibrogenic target in albumin-induced renal proximal tubule fibrosis. J Cell Biochem 2007 0.87
46 Chemical constituents from the Hydrangea chinensis. Arch Pharm Res 2003 0.86
47 Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models. Phytomedicine 2012 0.86
48 A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species. Free Radic Biol Med 2011 0.85
49 Tenuipyrone, a novel skeletal polyketide from the entomopathogenic fungus, Isaria tenuipes, cultivated in the presence of epigenetic modifiers. Org Lett 2011 0.85
50 Anti-cancer effect of liriodenine on human lung cancer cells. Kaohsiung J Med Sci 2004 0.84
51 Bioactive cembrane diterpenoids of Anisomeles indica. J Nat Prod 2008 0.84
52 Cytotoxic styrylpyrones from Goniothalamus amuyon. J Nat Prod 2003 0.84
53 Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro. Evid Based Complement Alternat Med 2013 0.84
54 The natural diterpenoid ovatodiolide induces cell cycle arrest and apoptosis in human oral squamous cell carcinoma Ca9-22 cells. Life Sci 2009 0.83
55 A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensis. Bioorg Med Chem Lett 2011 0.83
56 Inhibition of ATR-dependent signaling by protoapigenone and its derivative sensitizes cancer cells to interstrand cross-link-generating agents in vitro and in vivo. Mol Cancer Ther 2012 0.83
57 Cytotoxic principles from the formosan milkweed, Asclepias curassavica. J Nat Prod 2005 0.83
58 Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells. Chem Biol Interact 2013 0.83
59 Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis. Toxicol In Vitro 2009 0.82
60 Longicalycinin A, a new cytotoxic cyclic peptide from Dianthus superbus var. longicalycinus (MAXIM.) WILL. Chem Pharm Bull (Tokyo) 2005 0.82
61 Antioxidant activity, cytotoxicity, and DNA information of Glossogyne tenuifolia. J Agric Food Chem 2005 0.82
62 Bioactive constituents of Cirsium japonicum var. australe. J Nat Prod 2014 0.82
63 New benzoyl glucosides and cytotoxic pterosin sesquiterpenes from Pteris ensiformis Burm. Molecules 2008 0.82
64 Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana. Planta Med 2003 0.82
65 16-hydroxycleroda-3,13-dien-15,16-olide regulates the expression of histone-modifying enzymes PRC2 complex and induces apoptosis in CML K562 cells. Life Sci 2011 0.81
66 First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents. Org Biomol Chem 2010 0.81
67 Cytotoxic triterpenoids from the stems of Microtropis japonica. J Nat Prod 2009 0.81
68 Bioactive 6S-styryllactone constituents of Polyalthia parviflora. J Nat Prod 2014 0.80
69 Anti-inflammatory and cytotoxic neoflavonoids and benzofurans from Pterocarpus santalinus. J Nat Prod 2011 0.80
70 Limonoids from the seeds of Swietenia macrophylla with inhibitory activity against dengue virus 2. J Nat Prod 2014 0.80
71 Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. Arch Toxicol 2008 0.80
72 Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea. Bioorg Med Chem Lett 2010 0.80
73 Flavonol glycosides from Muehlenbeckia platyclada and their anti-inflammatory activity. Chem Pharm Bull (Tokyo) 2009 0.79
74 Digoniodiol, deoxygoniopypyrone A, and goniofupyrone A: three new styryllactones from Goniothalamus amuyon. Planta Med 2005 0.79
75 Geranyl flavonoid derivatives from the fresh leaves of Artocarpus communis and their anti-inflammatory activity. Planta Med 2012 0.79
76 Physalin B from Physalis angulata triggers the NOXA-related apoptosis pathway of human melanoma A375 cells. Food Chem Toxicol 2012 0.79
77 Antioxidant and tyrosinase inhibitory constituents from a desugared sugar cane extract, a byproduct of sugar production. J Agric Food Chem 2011 0.79
78 New cyclic peptides from the seeds of Annona squamosa L. and their anti-inflammatory activities. J Agric Food Chem 2007 0.79
79 Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, induces the production of anti-inflammatory cyclodepsipeptides from Beauveria felina. J Nat Prod 2013 0.79
80 An anti-inflammatory ent-kaurane from the stems of Annona squamosa that inhibits various human neutrophil functions. Planta Med 2005 0.79
81 Anti-diabetic properties of non-polar Toona sinensis Roem extract prepared by supercritical-CO2 fluid. Food Chem Toxicol 2011 0.79
82 Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π. Invest New Drugs 2010 0.79
83 Bioactive components from the heartwood of Pterocarpus santalinus. Bioorg Med Chem Lett 2011 0.79
84 Functional proteomics reveals the protective effects of saffron ethanolic extract on hepatic ischemia-reperfusion injury. Proteomics 2013 0.79
85 Cytotoxic phenanthrenequinones and 9,10-dihydrophenanthrenes from Calanthe arisanensis. J Nat Prod 2009 0.79
86 Protoapigenone derivatives: albumin binding properties and effects on HepG2 cells. J Photochem Photobiol B 2013 0.79
87 Chemical profiling of the cytotoxic triterpenoid-concentrating fraction and characterization of ergostane stereo-isomer ingredients from Antrodia camphorata. J Pharm Biomed Anal 2011 0.79
88 Microfluidic-assisted synthesis of hemispherical and discoidal chitosan microparticles at an oil/water interface. Electrophoresis 2012 0.78
89 Bioactive coumarins from the leaves of Murraya omphalocarpa. Planta Med 2003 0.78
90 The evaluation of 2,8-disubstituted benzoxazinone derivatives as anti-inflammatory and anti-platelet aggregation agents. Bioorg Med Chem Lett 2005 0.78
91 Camptothecinoids from the seeds of Taiwanese Nothapodytes foetida. Molecules 2008 0.78
92 Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells. Toxicol Appl Pharmacol 2011 0.78
93 A novel constituent from Rollinia mucosa, rollicosin, and a new approach to develop annonaceous acetogenins as potential antitumor agents. J Nat Prod 2003 0.78
94 The oestrogenic and anti-platelet activities of dihydrobenzofuroisocoumarins and homoisoflavonoids from Liriope platyphylla roots. Food Chem 2013 0.78
95 Using the pER8:GUS reporter system to screen for phytoestrogens from Caesalpinia sappan. J Nat Prod 2011 0.78
96 Safflower extract: a novel renal fibrosis antagonist that functions by suppressing autocrine TGF-beta. J Cell Biochem 2008 0.78
97 Cytotoxic ent-abietane diterpenes from Gelonium aequoreum. Phytochemistry 2007 0.78
98 Phyto-SERM constitutes from Flemingia macrophylla. Int J Mol Sci 2013 0.78
99 1,5-Diphenylpent-3-en-1-ynes and methyl naphthalene carboxylates from Lawsonia inermis and their anti-inflammatory activity. Phytochemistry 2013 0.77
100 (-)-Xanthienopyran, a new inhibitor of superoxide anion generation by activated neutrophils, and further constituents of the seeds of Xanthium strumarium. Planta Med 2008 0.77
101 2-hydroxy-4'-methoxychalcone inhibits proliferation and inflammation of human aortic smooth muscle cells by increasing the expression of peroxisome proliferator-activated receptor gamma. J Cardiovasc Pharmacol 2012 0.77
102 Inhibition of the Epstein-Barr virus lytic cycle by protoapigenone. J Gen Virol 2011 0.77
103 Potent inhibition of human neutrophil activations by bractelactone, a novel chalcone from Fissistigma bracteolatum. Toxicol Appl Pharmacol 2012 0.77
104 New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity. J Nat Prod 2003 0.77
105 Annonacin induces cell cycle-dependent growth arrest and apoptosis in estrogen receptor-α-related pathways in MCF-7 cells. J Ethnopharmacol 2011 0.77
106 Cyclopeptides with anti-inflammatory activity from seeds of Annona montana. J Nat Prod 2008 0.77
107 Cytotoxic sesquiterpene lactones from Pseudoelephantopus spicatus. J Nat Prod 2007 0.77
108 New cytotoxic 6-oxygenated 8,9-dihydrofurocoumarins, hedyotiscone A - C, from Hedyotis biflora. Planta Med 2006 0.76
109 Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma. Nat Prod Res 2005 0.76
110 Copper-catalyzed oxidative coupling of formamides with salicylaldehydes: synthesis of carbamates in the presence of a sensitive aldehyde group. J Org Chem 2014 0.76
111 Lupane-type triterpenoids from Microtropis fokienensis and Perrottetia arisanensis and the apoptotic effect of 28-hydroxy-3-oxo-lup-20(29)-en-30-al. J Nat Prod 2008 0.76
112 Association of altered cardiac autonomic function with psychopathology and metabolic profiles in schizophrenia. Psychiatry Res 2013 0.76
113 Isodesacetyluvaricin, an Annonaceous acetogenin, specifically inhibits gene expression of cyclooxygenase-2. J Nat Prod 2012 0.76
114 Antiplatelet effects of KW-7, a new inhibitor of cyclic nucleotide phosphodiesterases. Eur J Pharmacol 2004 0.76
115 6-Hydroxycleroda-3,13-dien-15,16-olide protects neuronal cells from lipopolysaccharide-induced neurotoxicity through the inhibition of microglia-mediated inflammation. Planta Med 2009 0.75
116 Stimulatory effects of squamocin, an Annonaceous acetogenin, on Ca(2+)-activated K+ current in cultured smooth muscle cells of human coronary artery. Chem Res Toxicol 2003 0.75
117 Inhibitory effects of ent-kauranes from the stems of Annona squamosa on superoxide anion generation by human neutrophils. Planta Med 2004 0.75
118 Iron-catalyzed oxidative direct α-C-H bond functionalization of cyclic ethers: selective C-O bond formation in the presence of a labile aldehyde group. Org Lett 2014 0.75
119 Acasiane A and B and farnesirane A and B, diterpene derivatives from the roots of Acacia farnesiana. Planta Med 2008 0.75
120 Synthesis and biological evaluation of phenanthrenes as cytotoxic agents with pharmacophore modeling and ChemGPS-NP prediction as topo II inhibitors. PLoS One 2012 0.75
121 Cytotoxic triterpenoids from the leaves of Microtropis fokienensis. J Nat Prod 2006 0.75
122 Direct semi-synthesis of the anticancer lead-drug protoapigenone from apigenin, and synthesis of further new cytotoxic protoflavone derivatives. PLoS One 2011 0.75
123 Tryptamine-derived amides and alkaloids from the seeds of Annona atemoya. J Nat Prod 2005 0.75
124 Antiplatelet and anti-HIV constituents from Euchresta formosana. Nat Prod Res 2003 0.75
125 Coumaronochromones and flavanones from Euchresta formosana roots. Phytochemistry 2002 0.75
126 New sesquiterpene lactones from the aerial parts of Pseudoelephantopus spicatus. Chem Pharm Bull (Tokyo) 2006 0.75
127 Chemical Constituents and LC-profile of Fresh Formosan Lonicera japonica Flower Buds. Nat Prod Commun 2016 0.75
128 Novel flavonoids of Thelypteris torresiana. Chem Pharm Bull (Tokyo) 2007 0.75
129 Macrophage mediated anti-proliferation effects of Anthodia camphorata non-polysaccharide based extracts on human hepatoma cells. Biosci Biotechnol Biochem 2011 0.75
130 Cytotoxic coumaronochromones from the roots of Euchresta formosana. Planta Med 2002 0.75
131 Antitumor agents. 233. Lantalucratins A-F, new cytotoxic naphthoquinones from Lantana involucrata. J Nat Prod 2004 0.75
132 Correction to first total synthesis of protoapigenone and its analogues as potent cytotoxic agents. J Med Chem 2012 0.75
133 New constituents from stems of Artabotrys uncinatus. Chem Pharm Bull (Tokyo) 2007 0.75
134 Nine new cytotoxic monotetrahydrofuranic Annonaceous acetogenins from Annona montana. Planta Med 2004 0.75
135 Antiplatelet aggregation effects of phenanthrenes from Calanthe arisanensis. Nat Prod Commun 2014 0.75
136 Mono-tetrahydrofuran annonaceous acetogenins from Annona squamosa as cytotoxic agents and calcium ion chelators. J Nat Prod 2008 0.75
137 Chemical constituents from Farfugium japonicum var. formosanum. Nat Prod Commun 2012 0.75
138 New constituents from stems of Goniothalamus amuyon. Chem Pharm Bull (Tokyo) 2006 0.75
139 2-Substituted benzoxazinone analogues as anti-human coronavirus (anti-HCoV) and ICAM-1 expression inhibition agents. Bioorg Med Chem Lett 2004 0.75
140 Montacin and cis-montacin, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona montana. J Nat Prod 2004 0.75
141 Novel cytotoxic monotetrahydrofuranic Annonaceous acetogenins from Annona montana. Bioorg Med Chem 2005 0.75
142 Antiplatelet aggregation coumarins from the leaves of Murraya omphalocarpa. Molecules 2008 0.75
143 Antiplatelet activity of synthetic pyrrolo-benzylisoquinolines. Bioorg Med Chem Lett 2003 0.75
144 Antiplatelet activity of benzylisoquinoline derivatives oxidized by cerium(IV) ammonium nitrate. Bioorg Med Chem Lett 2003 0.75
145 Inflammation Modulatory Phorbol Esters from the Seeds of Aquilaria malaccensis. J Nat Prod 2017 0.75
146 New dammarane-type saponins from the galls of Sapindus mukorossi. J Agric Food Chem 2005 0.75
147 Effect of isoquinoline alkaloids of different structural types on antiplatelet aggregation in vitro. Planta Med 2006 0.75
148 Efficient synthesis of boron-containing α-acyloxyamide analogs via microwave irradiation. Molecules 2013 0.75
149 Constituents of the Leaves of Pandanus utilis. Nat Prod Commun 2016 0.75
150 Indiosides G-K: steroidal glycosides with cytotoxic and anti-inflammatory activities from Solanum violaceum. J Nat Prod 2012 0.75