PubRank

Xian Chen

Author PubWeight™ 142.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Landscape of transcription in human cells. Nature 2012 20.18
2 Regulation of cellular metabolism by protein lysine acetylation. Science 2010 10.55
3 Long noncoding RNAs are rarely translated in two human cell lines. Genome Res 2012 2.64
4 Enhanced reversibility and unusual microstructure of a phase-transforming material. Nature 2013 2.21
5 Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol Cell Proteomics 2003 1.77
6 Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell 2004 1.73
7 Amino acid residue specific stable isotope labeling for quantitative proteomics. Rapid Commun Mass Spectrom 2002 1.54
8 Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity. Mol Pharmacol 2005 1.47
9 Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem 2013 1.47
10 Modifications of superoxide dismutase (SOD1) in human erythrocytes: a possible role in amyotrophic lateral sclerosis. J Biol Chem 2009 1.46
11 The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 2012 1.44
12 Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. Proc Natl Acad Sci U S A 2004 1.42
13 Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem 2009 1.38
14 Whole human genome proteogenomic mapping for ENCODE cell line data: identifying protein-coding regions. BMC Genomics 2013 1.38
15 Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers. J Am Chem Soc 2010 1.28
16 PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells. Cancer Res 2005 1.23
17 Pentamidine reduces hERG expression to prolong the QT interval. Br J Pharmacol 2005 1.23
18 Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression. Mol Cell Biol 2008 1.17
19 HDA18 affects cell fate in Arabidopsis root epidermis via histone acetylation at four kinase genes. Plant Cell 2013 1.16
20 Prolactin modulates the naive B cell repertoire. J Clin Invest 2003 1.14
21 Comparative proteomic analysis of all-trans-retinoic acid treatment reveals systematic posttranscriptional control mechanisms in acute promyelocytic leukemia. Blood 2004 1.13
22 Flightless I homolog negatively modulates the TLR pathway. J Immunol 2006 1.11
23 A new and facile synthesis of quinazoline-2,4(1H,3H)-diones. Org Lett 2009 1.10
24 Steroid receptor coactivator-1 upregulates integrin α₅ expression to promote breast cancer cell adhesion and migration. Cancer Res 2011 1.08
25 Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins. J Immunol 2009 1.06
26 The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest. Mol Cell Proteomics 2006 1.06
27 Synthesis of metal-selenide nanocrystals using selenium dioxide as the selenium precursor. Angew Chem Int Ed Engl 2008 1.06
28 In vivo dual-tagging proteomic approach in studying signaling pathways in immune response. J Proteome Res 2005 1.04
29 Improvement of image quality and radiation dose of CT perfusion of the brain by means of low-tube voltage (70 KV). Eur Radiol 2014 1.00
30 Crosstalk between Wnt/β-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells. PLoS One 2013 1.00
31 S100A8 and S100A9 are associated with colorectal carcinoma progression and contribute to colorectal carcinoma cell survival and migration via Wnt/β-catenin pathway. PLoS One 2013 0.99
32 Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J Orthop Res 2013 0.98
33 Global investigation of p53-induced apoptosis through quantitative proteomic profiling using comparative amino acid-coded tagging. Mol Cell Proteomics 2004 0.98
34 Upconverting near-infrared light through energy management in core-shell-shell nanoparticles. Angew Chem Int Ed Engl 2013 0.96
35 SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One 2012 0.96
36 Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metab 2012 0.95
37 Bone morphogenetic protein-9 effectively induces osteo/odontoblastic differentiation of the reversibly immortalized stem cells of dental apical papilla. Stem Cells Dev 2014 0.95
38 Residue-specific mass signatures for the efficient detection of protein modifications by mass spectrometry. Anal Chem 2002 0.94
39 Identification of lysine 37 of histone H2B as a novel site of methylation. PLoS One 2011 0.94
40 Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice. Exp Gerontol 2008 0.93
41 Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling. J Biol Chem 2011 0.93
42 Use of deuterium-labeled lysine for efficient protein identification and peptide de novo sequencing. Anal Chem 2002 0.92
43 Precise peptide sequencing and protein quantification in the human proteome through in vivo lysine-specific mass tagging. J Am Soc Mass Spectrom 2003 0.92
44 Proteomic study for the cellular responses to Cd2+ in Schizosaccharomyces pombe through amino acid-coded mass tagging and liquid chromatography tandem mass spectrometry. Mol Cell Proteomics 2004 0.91
45 14-3-3 epsilon dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-alpha-induced time course-dependent NF-kappaB activity. J Proteome Res 2010 0.91
46 Comparative gene expression profiling in human-induced pluripotent stem cell--derived cardiocytes and human and cynomolgus heart tissue. Toxicol Sci 2012 0.90
47 Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma. J Proteome Res 2010 0.90
48 A new method for modeling coalescent processes with recombination. BMC Bioinformatics 2014 0.90
49 Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. Curr Cancer Drug Targets 2014 0.89
50 Pharmacokinetic-pharmacodynamic modelling of the effect of Moxifloxacin on QTc prolongation in telemetered cynomolgus monkeys. J Pharmacol Toxicol Methods 2011 0.89
51 Isolation and characterization of hantavirus carried by Apodemus peninsulae in Jilin, China. J Gen Virol 2007 0.89
52 Mesoporous silica nanoreactors for highly efficient proteolysis. Chemistry 2005 0.89
53 Analysis of the protein complex associated with 14-3-3 epsilon by a deuterated-leucine labeling quantitative proteomics strategy. J Chromatogr B Analyt Technol Biomed Life Sci 2009 0.87
54 S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway. Int J Oncol 2013 0.87
55 Destabilization of heterologous proteins mediated by the GSK3β phosphorylation domain of the β-catenin protein. Cell Physiol Biochem 2013 0.87
56 Bioinformatics analysis of metastasis-related proteins in hepatocellular carcinoma. World J Gastroenterol 2008 0.87
57 Plasma metabolic fingerprinting of childhood obesity by GC/MS in conjunction with multivariate statistical analysis. J Pharm Biomed Anal 2010 0.87
58 Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLoS One 2013 0.87
59 Mangiferin attenuate sepsis-induced acute kidney injury via antioxidant and anti-inflammatory effects. Am J Nephrol 2014 0.87
60 Finite element contact analysis of the hip joint. Med Biol Eng Comput 2006 0.87
61 Glutathiolated Ras: characterization and implications for Ras activation. Free Radic Biol Med 2012 0.86
62 Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Rep 2013 0.86
63 Radix tetrastigma hemsleyani flavone induces apoptosis in human lung carcinoma a549 cells by modulating the MAPK pathway. Asian Pac J Cancer Prev 2013 0.85
64 PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics. J Proteome Res 2013 0.85
65 Modulation of β-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci 2013 0.85
66 Influence of cartilage extracellular matrix molecules on cell phenotype and neocartilage formation. Tissue Eng Part A 2013 0.85
67 Single peptide-based protein identification in human proteome through MALDI-TOF MS coupled with amino acids coded mass tagging. Anal Chem 2003 0.84
68 Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis. Microbiology 2013 0.84
69 Proteomic dissection of agonist-specific TLR-mediated inflammatory responses on macrophages at subcellular resolution. J Proteome Res 2008 0.84
70 Multidetector CT in evaluating blood supply of hepatocellular carcinoma after transcatheter arterial chemoembolization. World J Gastroenterol 2004 0.83
71 Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells. Proteomics 2009 0.83
72 Downregulation of the c-MYC target gene, peroxiredoxin III, contributes to arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Int J Cancer 2009 0.83
73 Activation of the interleukin-4/signal transducer and activator of transcription 6 signaling pathway and homeodomain-interacting protein kinase 2 production by tonsillar mononuclear cells in IgA nephropathy. Am J Nephrol 2013 0.83
74 Meniscus tissue engineering using a novel combination of electrospun scaffolds and human meniscus cells embedded within an extracellular matrix hydrogel. J Orthop Res 2015 0.83
75 Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. J Biomed Mater Res A 2013 0.82
76 Proteomics analysis of stage-specific proteins expressed in human squamous cell lung carcinoma tissues. Cancer Biomark 2005 0.82
77 In vivo profiling endogenous interactions with knock-out in mammalian cells. Anal Chem 2009 0.82
78 Quantitative proteomic analysis of LPS-induced differential immune response associated with TLR4 Polymorphisms by multiplex amino acid coded mass tagging. Proteomics 2008 0.82
79 Comparison of the membrane proteome of virulent Mycobacterium tuberculosis and the attenuated Mycobacterium bovis BCG vaccine strain by label-free quantitative proteomics. J Proteome Res 2013 0.82
80 A new strategy of outlier detection for QSAR/QSPR. J Comput Chem 2010 0.82
81 Ultrasensitive electrochemical detection of cancer-associated circulating microRNA in serum samples based on DNA concatamers. Biosens Bioelectron 2013 0.81
82 Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. PLoS One 2013 0.81
83 Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics. Proteomics 2011 0.81
84 Renal biopsy findings of patients presenting with isolated hematuria: disease associations. Am J Nephrol 2012 0.81
85 Nanopore-based proteolytic reactor for sensitive and comprehensive proteomic analyses. Anal Chem 2006 0.81
86 Multiphysics simulation of blood flow and LDL transport in a porohyperelastic arterial wall model. J Biomech Eng 2007 0.81
87 Global analysis of the rat and human platelet proteome - the molecular blueprint for illustrating multi-functional platelets and cross-species function evolution. Proteomics 2010 0.81
88 Induction of endoplasmic reticulum stress by sonoporation: linkage to mitochondria-mediated apoptosis initiation. Ultrasound Med Biol 2013 0.81
89 GOFAST: an integrated approach for efficient and comprehensive membrane proteome analysis. Anal Chem 2012 0.81
90 Large-scale quantitative proteomic study of PUMA-induced apoptosis using two-dimensional liquid chromatography-mass spectrometry coupled with amino acid-coded mass tagging. J Proteome Res 2004 0.81
91 Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex. J Proteome Res 2009 0.81
92 Detection of Ras GTPase protein radicals through immuno-spin trapping. Free Radic Biol Med 2012 0.80
93 Subcellular quantitative proteomics reveals multiple pathway cross-talk that coordinates specific signaling and transcriptional regulation for the early host response to LPS. J Proteome Res 2010 0.80
94 Simulation study on the effect of fiber loss to the compound action potential of a sural nerve. Conf Proc IEEE Eng Med Biol Soc 2007 0.80
95 Inactivation of the phosphatidylinositol 3-kinase/Akt pathway is involved in BMP9-mediated tumor-suppressive effects in gastric cancer cells. J Cell Biochem 2015 0.79
96 Disfavoring macrocycle b fragments by constraining torsional freedom: the "twisted" case of QWFGLM b6. J Am Soc Mass Spectrom 2012 0.79
97 Precise proteomic identification using mass spectrometry coupled with stable isotope labeling. Analyst 2005 0.79
98 Using stable-isotope-labeled proteins for hydrogen exchange studies in complex mixtures. Anal Chem 2002 0.79
99 Th1/Th2 polarization in tonsillar lymphocyte form patients with IgA nephropathy. Ren Fail 2013 0.79
100 14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage. PLoS One 2013 0.79
101 In vitro phosphorylation of the focal adhesion targeting domain of focal adhesion kinase by Src kinase. Biochemistry 2012 0.79
102 Amplified spontaneous emission and lasing from lanthanide-doped up-conversion nanocrystals. ACS Nano 2013 0.79
103 Quantitative proteomic analysis of a paired human liver healthy versus carcinoma cell lines with the same genetic background to identify potential hepatocellular carcinoma markers. Proteomics Clin Appl 2009 0.79
104 β-elemene inhibits the proliferation of T24 bladder carcinoma cells through upregulation of the expression of Smad4. Mol Med Rep 2012 0.78
105 Efficient in-gel proteolysis accelerated by infrared radiation for protein identification. J Proteome Res 2008 0.78
106 14-3-3ε boosts bleomycin-induced DNA damage response by inhibiting the drug-resistant activity of MVP. J Proteome Res 2013 0.78
107 Abundance- and Activity-Based Proteomics in Platelet Biology. Curr Proteomics 2011 0.78
108 Nkx3.1 functions as para-transcription factor to regulate gene expression and cell proliferation in non-cell autonomous manner. J Biol Chem 2012 0.78
109 A sensitive aptasensor for adenosine based on the quenching of Ru(bpy)(3)(2+)-doped silica nanoparticle ECL by ferrocene. Chem Commun (Camb) 2010 0.78
110 Direct detection of circulating microRNAs in serum of cancer patients by coupling protein-facilitated specific enrichment and rolling circle amplification. Chem Commun (Camb) 2014 0.78
111 A difunctional DNA-AuNP dendrimer coupling DNAzyme with intercalators for femtomolar detection of nucleic acids. Chem Commun (Camb) 2013 0.78
112 Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells. Toxicol Appl Pharmacol 2007 0.78
113 Dissection of DEN-induced platelet proteome changes reveals the progressively dys-regulated pathways indicative of hepatocarcinogenesis. J Proteome Res 2010 0.78
114 Enhancing TOF/TOF-based de novo sequencing capability for high throughput protein identification with amino acid-coded mass tagging. J Proteome Res 2005 0.78
115 Flight of a cytidine deaminase complex with an imperfect transition state analogue inhibitor: mass spectrometric evidence for the presence of a trapped water molecule. Biochemistry 2012 0.77
116 Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy. Chem Commun (Camb) 2015 0.77
117 Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats. Can J Physiol Pharmacol 2015 0.77
118 Inflammatory stress promotes lipid accumulation in the aorta and liver of SR-A/CD36 double knock-out mice. Mol Med Rep 2010 0.76
119 Comprehensive profiling of metastasis-related proteins in paired hepatocellular carcinoma cells with different metastasis potentials. Proteomics Clin Appl 2009 0.75
120 Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nat Commun 2017 0.75
121 Validation of DNA sequences using mass spectrometry coupled with nucleoside mass tagging. Genome Res 2002 0.75
122 Neuronal expression of inducible nitric oxide synthase in hypothyroid rat. Neuro Endocrinol Lett 2010 0.75
123 Enhancing Multiphoton Upconversion from NaYF4:Yb/Tm@NaYF4 Core-Shell Nanoparticles via the Use of Laser Cavity. ACS Nano 2016 0.75
124 [Helicobacter pylori cytotoxin associated protein CagA regulates gastrin gene promoter activity]. Zhonghua Zhong Liu Za Zhi 2010 0.75
125 The Value of lncRNA HULC as a Prognostic Factor for Survival of Cancer Outcome: A Meta-Analysis. Cell Physiol Biochem 2017 0.75
126 Incorporation of a fluorous diazirine group into phosphatidylinositol 4,5-bisphosphate to illustrate its interaction with ADP-ribosylation factor 1. Org Biomol Chem 2012 0.75
127 Navigation system with real-time finite element analysis for minimally invasive surgery. Conf Proc IEEE Eng Med Biol Soc 2013 0.75
128 [Progress in the study of centrins, a centrosome protein]. Sheng Li Ke Xue Jin Zhan 2004 0.75
129 Cerium oxide-triggered 'one-to-many' catalytic cycling strategy for in situ amplified electronic signal of low-abundance protein. Analyst 2013 0.75
130 A General Strategy for Ligand Exchange on Upconversion Nanoparticles. Inorg Chem 2017 0.75
131 [The value of MRI 3D-VIBE systems applied to preoperative estimate of hepatic portal cholangiocarcinoma]. Sichuan Da Xue Xue Bao Yi Xue Ban 2006 0.75
132 Prevalence of Occult Hepatitis C Virus Infection among Blood Donors in Jiangsu, China. Intervirology 2017 0.75
133 [Expression of human TFF3 in Escherichia coli]. Sichuan Da Xue Xue Bao Yi Xue Ban 2010 0.75
134 An optimized magnetite microparticle-based phosphopeptide enrichment strategy for identifying multiple phosphorylation sites in an immunoprecipitated protein. Anal Biochem 2010 0.75
135 [Restraining degeneration of punctured intervertebral discs by transplantation of rabbit nucleus pulposus cells and marrow stroma cells]. Sichuan Da Xue Xue Bao Yi Xue Ban 2009 0.75
136 Blast-Burn Combined Injury Followed by Immediate Seawater Immersion Induces Hemodynamic Changes and Metabolic Acidosis: An Experimental Study in a Canine Model. Clin Lab 2016 0.75
137 [Optimal scanning collimation for segmental bronchi: experimental study with low-dose helical CT]. Sichuan Da Xue Xue Bao Yi Xue Ban 2004 0.75
138 Evidence of two key intermediates contributing to the selectivity of P450-biomimetic oxidation of sulfides to sulfoxides and sulfones. Chem Asian J 2012 0.75
139 [Comparison of the efficacy of gadobutrol and multihance in contrast-enhanced MRI for diagnosis of brain metastasis in lung cancer]. Sichuan Da Xue Xue Bao Yi Xue Ban 2012 0.75
140 Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids. J Nephrol 2012 0.75
141 Promoted healing of femoral defects with in situ grown fibrous composites of hydroxyapatite and poly(DL-lactide). J Biomed Mater Res A 2012 0.75
142 [Cloning the lvgA gene of Legionella pneumophila and detecting its expression in Escherichia coli]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2006 0.75
143 Alignment and structural control of nitrogen-doped carbon nanotubes by utilizing precursor concentration effect. Nanotechnology 2014 0.75
144 Gold nanoparticle assembly microfluidic reactor for efficient on-line proteolysis. Mol Cell Proteomics 2007 0.75
145 Simultaneous photoacoustic imaging technique using an acoustic imaging lens. J Biomed Opt 2009 0.75
146 Real-time nonlinear FEM with neural network for simulating soft organ model deformation. Med Image Comput Comput Assist Interv 2008 0.75
147 [Establishment of Mongolian gerbil model of gastric cancer induced by Helicobacter pylori infection and its proteomics analysis]. Zhonghua Bing Li Xue Za Zhi 2014 0.75
148 Combined mesophilic anaerobic and thermophilic aerobic digestion process: effect on sludge degradation and variation of sludge property. Appl Biochem Biotechnol 2013 0.75
149 Effect of dialysis dose and membrane flux on hemoglobin cycling in hemodialysis patients. Hemodial Int 2014 0.75
150 [One-stop examination of thoracic and abdominal injuries in earthquake victims using multi-slice CT]. Sichuan Da Xue Xue Bao Yi Xue Ban 2011 0.75
151 [The characterization value of feridex-enhanced MR imaging for focal hepatic lesions in reference to their histological pathology]. Zhonghua Gan Zang Bing Za Zhi 2005 0.75
152 The study of Chinese medicinal herbal formula Shen San Fang in the treatment of experimental IgA nephropathy. Am J Chin Med 2005 0.75
153 Quantitative proteomic dissection of a native 14-3-3ε interacting protein complex associated with hepatocellular carcinoma. Amino Acids 2013 0.75
154 [Association between the expression and methylation of energy-related genes with Helicobacter pylori infection in gastric cancer]. Zhonghua Yi Xue Za Zhi 2012 0.75
155 Development and validation of LC-MS method for the determination of lisinopril in human plasma and its application in a bioequivalence study. J Chromatogr Sci 2008 0.75
156 A modified nanospray tip coupled to a mass spectrometer for analyzing enzymatic peptides. Rapid Commun Mass Spectrom 2004 0.75
157 [Dynamic extraction process of salvianolic acids]. Zhongguo Zhong Yao Za Zhi 2010 0.75
158 [Peripheral MR angiography without contrast agent using fresh blood imaging (FBI) with ECG-trigger: initial experience]. Sichuan Da Xue Xue Bao Yi Xue Ban 2012 0.75
159 [Legionella pneumophila lvgA and Hsp60 gene splicing and the fusion gene expression in E.coli]. Nan Fang Yi Ke Da Xue Xue Bao 2006 0.75
160 Interaction of glycyrrhetinic acid, furosemide and hydrochlorothiazide with bovine serum albumin and their displacement interactions: capillary electrophoresis and fluorescence quenching study. Biomed Chromatogr 2008 0.75
161 Solvent-free syntheses of hierarchically porous aluminophosphate-based zeolites with AEL and AFI structures. Chemistry 2014 0.75