Published in Mol Oncol on February 02, 2010
Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate. Mol Oncol (2010) 0.90
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Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Mol Cancer Res (2014) 0.76
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Gender differences in UVB-induced skin carcinogenesis, inflammation, and DNA damage. Cancer Res (2007) 1.57
Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature (2007) 1.54
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Imaging of tumor glucose utilization with positron emission tomography. Cancer Metastasis Rev (2008) 0.99
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Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab (2007) 11.79
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci U S A (2010) 3.03
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Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease. Am J Geriatr Psychiatry (2002) 2.80
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study. J Cereb Blood Flow Metab (2005) 2.52
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Persistent Sin Nombre virus infection in the deer mouse (Peromyscus maniculatus) model: sites of replication and strand-specific expression. J Virol (2003) 2.09
The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells. Proc Natl Acad Sci U S A (2003) 1.84
Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discov (2012) 1.71
Tight glycemic control increases metabolic distress in traumatic brain injury: a randomized controlled within-subjects trial. Crit Care Med (2012) 1.62
Effects of gut-targeted 15-LOX-1 transgene expression on colonic tumorigenesis in mice. J Natl Cancer Inst (2012) 1.58
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Estimation of the 18F-FDG input function in mice by use of dynamic small-animal PET and minimal blood sample data. J Nucl Med (2007) 1.42
Chronic stress and susceptibility to skin cancer. J Natl Cancer Inst (2005) 1.41
Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Mol Cell Biol (2009) 1.40
IKKalpha is required to maintain skin homeostasis and prevent skin cancer. Cancer Cell (2008) 1.38
Cyclo-oxygenase-2 plays a critical role in UV-induced skin carcinogenesis. Photochem Photobiol (2008) 1.38
A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas. Proc Natl Acad Sci U S A (2006) 1.37
Serotonin 1A receptors in the living brain of Alzheimer's disease patients. Proc Natl Acad Sci U S A (2006) 1.34
Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers. Int J Cancer (2008) 1.34
Effects of administration route, dietary condition, and blood glucose level on kinetics and uptake of 18F-FDG in mice. J Nucl Med (2011) 1.31
In vivo quantitation of glucose metabolism in mice using small-animal PET and a microfluidic device. J Nucl Med (2007) 1.30
Differential cerebral metabolic changes with paroxetine treatment of obsessive-compulsive disorder vs major depression. Arch Gen Psychiatry (2002) 1.30
Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells. PLoS One (2010) 1.28
Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. J Biol Chem (2002) 1.28
TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling. J Biol Chem (2005) 1.28
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development. Cancer Res (2005) 1.27
Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography. Proc Natl Acad Sci U S A (2009) 1.26
18F-fluorothymidine kinetics of malignant brain tumors. Eur J Nucl Med Mol Imaging (2007) 1.25
The influence of innate and pre-existing immunity on adenovirus therapy. J Cell Biochem (2009) 1.25
Imaging cyclooxygenase-2 (Cox-2) gene expression in living animals with a luciferase knock-in reporter gene. Mol Imaging Biol (2006) 1.24
Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression. Neoplasia (2008) 1.24
Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses. Nat Neurosci (2009) 1.24
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. Cancer Res (2007) 1.24
Requirement for deoxycytidine kinase in T and B lymphocyte development. Proc Natl Acad Sci U S A (2009) 1.23
The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res (2005) 1.22
Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Sci Transl Med (2012) 1.22
Quantitative high-performance liquid chromatography/electrospray ionization tandem mass spectrometric analysis of 2- and 3-series prostaglandins in cultured tumor cells. Anal Biochem (2002) 1.21
1-11C-acetate kinetics of prostate cancer. J Nucl Med (2008) 1.20
Phase I, first-in-human study of BMS747158, a novel 18F-labeled tracer for myocardial perfusion PET: dosimetry, biodistribution, safety, and imaging characteristics after a single injection at rest. J Nucl Med (2011) 1.18
18F-FDOPA kinetics in brain tumors. J Nucl Med (2007) 1.18
Noninvasive measurement of myocardial activity concentrations and perfusion defect sizes in rats with a new small-animal positron emission tomograph. Circulation (2002) 1.18
Quantification of cerebral glucose metabolic rate in mice using 18F-FDG and small-animal PET. J Nucl Med (2009) 1.17
Molecular imaging in the development of cancer therapeutics. Annu Rev Med (2006) 1.17
Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1. J Neurosci Res (2002) 1.16
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. J Exp Med (2012) 1.16
Targeted genetic disruption of peroxisome proliferator-activated receptor-delta and colonic tumorigenesis. J Natl Cancer Inst (2009) 1.16
Conditional knockout mouse for tissue-specific disruption of the cyclooxygenase-2 (Cox-2) gene. Genesis (2006) 1.15
A role for cyclooxygenase-2 in ultraviolet light-induced skin carcinogenesis. Mol Carcinog (2007) 1.15
Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression. Carcinogenesis (2010) 1.15
Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem (2002) 1.15
Noninvasive measurement of cardiovascular function in mice with high-temporal-resolution small-animal PET. J Nucl Med (2006) 1.14
Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development. Cancer Res (2002) 1.14
Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis. Carcinogenesis (2010) 1.14
Accuracy of a method using short inhalation of (15)O-O(2) for measuring cerebral oxygen extraction fraction with PET in healthy humans. J Nucl Med (2004) 1.13
Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography. Cancer Gene Ther (2005) 1.13
Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells. J Lipid Res (2004) 1.11
Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia. Cancer Epidemiol Biomarkers Prev (2002) 1.10
Cell intrinsic role of COX-2 in pancreatic cancer development. Mol Cancer Ther (2012) 1.10
Experimental bioluminescence tomography with fully parallel radiative-transfer-based reconstruction framework. Opt Express (2009) 1.10
Multiple signaling pathways are responsible for prostaglandin E2-induced murine keratinocyte proliferation. Mol Cancer Res (2008) 1.10
Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery. Circulation (2004) 1.10
Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfal binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo. J Bone Miner Res (2002) 1.10
DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo. Oncogene (2004) 1.09
Molecular mechanisms of mouse skin tumor promotion. Cancers (Basel) (2010) 1.09
Selective metabolic reduction in gray matter acutely following human traumatic brain injury. J Neurotrauma (2004) 1.09
Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region. Eur J Nucl Med Mol Imaging (2009) 1.08
Technology Insight: novel imaging of molecular targets is an emerging area crucial to the development of targeted drugs. Nat Clin Pract Oncol (2008) 1.08
Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors. Cell Microbiol (2003) 1.07
Dynamic PET/CT with 11C-acetate in prostate cancer. J Nucl Med (2012) 1.06
Thiazolidinediones inhibit insulin-like growth factor-i-induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity. Cancer Res (2006) 1.05
GATA-6 transcriptional regulation of 15-lipoxygenase-1 during NSAID-induced apoptosis in colorectal cancer cells. Cancer Res (2002) 1.05
Functional expression of SGLTs in rat brain. Am J Physiol Cell Physiol (2010) 1.04
Improved parametric image generation using spatial-temporal analysis of dynamic PET studies. Neuroimage (2002) 1.04
Unexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning. J Biol Chem (2010) 1.03
Altered hippocampal short-term plasticity and associative memory in synaptotagmin IV (-/-) mice. Hippocampus (2004) 1.03
Transitional cell hyperplasia and carcinomas in urinary bladders of transgenic mice with keratin 5 promoter-driven cyclooxygenase-2 overexpression. Cancer Res (2005) 1.03
Spectrally resolved bioluminescence tomography with the third-order simplified spherical harmonics approximation. Phys Med Biol (2009) 1.02
Kinetics of 3'-deoxy-3'-18F-fluorothymidine during treatment monitoring of recurrent high-grade glioma. J Nucl Med (2010) 1.02
Visualizing pathology deposits in the living brain of patients with Alzheimer's disease. Methods Enzymol (2006) 1.02
Movement correction method for human brain PET images: application to quantitative analysis of dynamic 18F-FDDNP scans. J Nucl Med (2010) 1.01
Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer. Cancer Prev Res (Phila) (2011) 1.01
Correlation of regional metabolic rates of glucose with glasgow coma scale after traumatic brain injury. J Nucl Med (2003) 1.01
Acute changes in regional cerebral (18)F-FDG kinetics in patients with traumatic brain injury. J Nucl Med (2004) 1.01
Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter. Cancer Res (2007) 1.00
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent. Mol Carcinog (2007) 1.00
Derivation of a compartmental model for quantifying 64Cu-DOTA-RGD kinetics in tumor-bearing mice. J Nucl Med (2009) 0.99
Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin. Diabetes (2008) 0.99
Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice. Cancer Prev Res (Phila) (2009) 0.99
Genes preferentially induced by depolarization after concussive brain injury: effects of age and injury severity. J Neurotrauma (2002) 0.98
Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5. Immunogenetics (2002) 0.98
Dissecting molecular mechanisms in the living brain of dementia patients. Acc Chem Res (2009) 0.98
Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF. J Biol Chem (2011) 0.98
Transgenic mouse for conditional, tissue-specific Cox-2 overexpression. Genesis (2006) 0.97
Indirect monitoring of endogenous gene expression by positron emission tomography (PET) imaging of reporter gene expression in transgenic mice. Mol Imaging Biol (2002) 0.97
IL-15 but not IL-2 rapidly induces lethal xenogeneic graft-versus-host disease. Blood (2005) 0.97
Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia. Cancer Prev Res (Phila) (2011) 0.97