PubRank

Debra K Newman

Author PubWeight™ 41.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. Arterioscler Thromb Vasc Biol 2003 2.30
2 Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2008 1.78
3 High-throughput phosphotyrosine profiling using SH2 domains. Mol Cell 2007 1.72
4 Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. Blood 2012 1.72
5 The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy. Cancer Biol Ther 2006 1.65
6 Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling. Blood 2011 1.59
7 Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets. Blood 2008 1.54
8 Platelet PECAM-1 inhibits thrombus formation in vivo. Blood 2005 1.53
9 Endothelial cell PECAM-1 confers protection against endotoxic shock. Am J Physiol Heart Circ Physiol 2004 1.44
10 PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. Blood 2003 1.33
11 PECAM-1: conflicts of interest in inflammation. Life Sci 2010 1.30
12 Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. J Clin Invest 2009 1.24
13 TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. J Immunol 2010 1.15
14 Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. Am J Physiol Regul Integr Comp Physiol 2005 1.05
15 Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface. Blood 2004 1.05
16 PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. Blood 2003 1.01
17 The alleles of PECAM-1. Gene 2006 1.00
18 Platelet signaling. Handb Exp Pharmacol 2012 0.99
19 Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets. Biochem J 2007 0.98
20 Neutrophil transmigration mediated by the neutrophil-specific antigen CD177 is influenced by the endothelial S536N dimorphism of platelet endothelial cell adhesion molecule-1. J Immunol 2010 0.98
21 The proinflammatory phenotype of PECAM-1-deficient mice results in atherogenic diet-induced steatohepatitis. Am J Physiol Gastrointest Liver Physiol 2007 0.97
22 Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity. J Cell Sci 2011 0.96
23 Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. Blood 2011 0.95
24 Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. Blood 2011 0.95
25 Phospholipase Cgamma2 contributes to stable thrombus formation on VWF. FEBS Lett 2004 0.93
26 A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood 2011 0.93
27 Critical role for mouse marginal zone B cells in PF4/heparin antibody production. Blood 2013 0.91
28 Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. Biochemistry 2013 0.91
29 An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion. EMBO J 2004 0.90
30 Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. Am J Physiol Heart Circ Physiol 2003 0.88
31 Mechanism of outside-in {alpha}IIb{beta}3-mediated activation of human platelets by the colonizing Bacterium, Streptococcus gordonii. Arterioscler Thromb Vasc Biol 2010 0.85
32 B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia. Blood 2013 0.84
33 An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci 2008 0.83
34 PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. Life Sci 2011 0.82
35 The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B. J Immunol 2010 0.82
36 Cadherin 6 has a functional role in platelet aggregation and thrombus formation. Arterioscler Thromb Vasc Biol 2012 0.80