Published in J Allergy Clin Immunol on February 01, 2010
The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort. J Allergy Clin Immunol (2012) 1.52
Accurate prediction of severe allergic reactions by a small set of environmental parameters (NDVI, temperature). PLoS One (2015) 1.38
Allergic asthma: influence of genetic and environmental factors. J Biol Chem (2011) 1.30
Asthma genetics and personalised medicine. Lancet Respir Med (2014) 1.17
Allergy as an epithelial barrier disease. Clin Transl Allergy (2011) 0.96
The effect of CD14 and TLR4 gene polymorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study. BMC Pulm Med (2014) 0.91
IgE and mast cells in host defense against parasites and venoms. Semin Immunopathol (2016) 0.88
Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol (2011) 0.86
Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population. BMC Med Genet (2011) 0.85
Network analysis of single nucleotide polymorphisms in asthma. J Asthma Allergy (2010) 0.84
Interaction of prenatal maternal smoking, interleukin 13 genetic variants and DNA methylation influencing airflow and airway reactivity. Clin Epigenetics (2013) 0.83
Insights into pathophysiology of dystropy through the analysis of gene networks: an example of bronchial asthma and tuberculosis. Immunogenetics (2014) 0.83
Genome-wide association study identifies PERLD1 as asthma candidate gene. BMC Med Genet (2011) 0.83
Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example. Environ Health (2013) 0.83
Allergic diseases and risk of hematopoietic malignancies in a cohort of postmenopausal women: a report from the Iowa Women's Health Study. Cancer Epidemiol Biomarkers Prev (2014) 0.81
DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma. J Control Release (2014) 0.81
An ADAM33 polymorphism associates with progression of preschool wheeze into childhood asthma: a prospective case-control study with replication in a birth cohort study. PLoS One (2015) 0.81
The tyrosine kinase inhibitor dasatinib reduces lung inflammation and remodelling in experimental allergic asthma. Br J Pharmacol (2016) 0.81
Association analysis of single nucleotide polymorphisms at five loci: comparison between atopic dermatitis and asthma in the Chinese Han population. PLoS One (2012) 0.80
Involvement of human histamine N-methyltransferase gene polymorphisms in susceptibility to atopic dermatitis in korean children. Allergy Asthma Immunol Res (2011) 0.79
Allergic sensitization and filaggrin variants predispose to the comorbidity of eczema, asthma, and rhinitis: results from the Isle of Wight birth cohort. Clin Exp Allergy (2014) 0.79
Allergic diseases among children: nutritional prevention and intervention. Ther Clin Risk Manag (2016) 0.78
Aldose reductase inhibition suppresses airway inflammation. Chem Biol Interact (2011) 0.77
The relationship between interleukin-18 polymorphisms and allergic disease: a meta-analysis. Biomed Res Int (2014) 0.77
Barriers to inhaled gene therapy of obstructive lung diseases: A review. J Control Release (2016) 0.77
Unravelling the role of ADAM 33 in asthma. Indian J Med Res (2013) 0.77
IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity. J Allergy Clin Immunol (2015) 0.76
Genetic polymorphisms and asthma: findings from a case-control study in the Madeira island population. Biol Res (2014) 0.76
Allergy-specific Phenome-Wide Association Study for Immunogenes in Turkish Children. Sci Rep (2016) 0.76
Association between the Interaction of Key Genes Involved in Effector T-Cell Pathways and Susceptibility to Developallergic Rhinitis: A Population-Based Case-Control Association Study. PLoS One (2015) 0.75
Genes Interacting with Occupational Exposures to Low Molecular Weight Agents and Irritants on Adult-Onset Asthma in Three European Studies. Environ Health Perspect (2016) 0.75
Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case-control cohort. BMC Dermatol (2014) 0.75
Air pollution and health. Lancet (2002) 9.57
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature (2002) 8.28
Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med (2002) 6.52
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med (2005) 6.05
Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med (2006) 5.90
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study. Lancet (2002) 3.11
Pathogenesis of asthma. Clin Exp Allergy (2008) 2.93
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med (2004) 2.81
The airway epithelium: structural and functional properties in health and disease. Respirology (2003) 2.73
Defective epithelial barrier function in asthma. J Allergy Clin Immunol (2011) 2.73
The mouse trap: It still yields few answers in asthma. Am J Respir Crit Care Med (2006) 2.68
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med (2009) 2.56
Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2006) 2.44
The role of the mast cell in the pathophysiology of asthma. J Allergy Clin Immunol (2006) 2.35
Airway remodeling in asthma: new insights. J Allergy Clin Immunol (2003) 2.32
The European Respiratory Society plans its future: the 2013-2018 strategic plan. Eur Respir J (2014) 2.02
Personal exposure to nitrogen dioxide (NO2) and the severity of virus-induced asthma in children. Lancet (2003) 1.96
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial. Am J Respir Crit Care Med (2002) 1.90
Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma. Am J Respir Crit Care Med (2004) 1.88
Severe asthma in adults: what are the important questions? J Allergy Clin Immunol (2007) 1.85
Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation. Am J Respir Crit Care Med (2011) 1.84
Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis. Am J Respir Cell Mol Biol (2002) 1.73
Factors associated with mortality after an asthma admission: a national United Kingdom database analysis. Respir Med (2007) 1.71
Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects. J Infect Dis (2002) 1.59
Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis. J Infect Dis (2008) 1.59
Cooperative effects of Th2 cytokines and allergen on normal and asthmatic bronchial epithelial cells. J Immunol (2002) 1.51
Tumor necrosis factor alpha (TNF-α) autoregulates its expression and induces adhesion molecule expression in asthma. Clin Immunol (2011) 1.45
The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. Am J Respir Cell Mol Biol (2004) 1.42
Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. Am J Respir Crit Care Med (2005) 1.40
Autocrine ligands for the epidermal growth factor receptor mediate interleukin-8 release from bronchial epithelial cells in response to cigarette smoke. Am J Respir Cell Mol Biol (2002) 1.36
Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. Am J Respir Crit Care Med (2009) 1.35
Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways. Part Fibre Toxicol (2009) 1.35
Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium. Am J Respir Cell Mol Biol (2003) 1.35
IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations. J Allergy Clin Immunol (2007) 1.34
A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. Am J Respir Crit Care Med (2002) 1.33
Animal models of asthma: value, limitations and opportunities for alternative approaches. Drug Discov Today (2011) 1.32
MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma. PLoS One (2010) 1.30
Enzyme potentiated desensitisation in treatment of seasonal allergic rhinitis: double blind randomised controlled study. BMJ (2003) 1.29
Allergic diseases and asthma: a major global health concern. Curr Opin Allergy Clin Immunol (2012) 1.26
Analysis of novel disease-related genes in bronchial asthma. Cytokine (2002) 1.22
The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma. J Allergy Clin Immunol (2008) 1.21
Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma. Thorax (2010) 1.20
IL-4 receptor alpha is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets. J Immunol (2006) 1.15
Diagnostic molecular biomarkers for malignant pleural effusions. Future Oncol (2011) 1.15
Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects. J Allergy Clin Immunol (2002) 1.13
Kinetic analysis of the interleukin-13 receptor complex. J Biol Chem (2002) 1.12
The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial. Am J Respir Crit Care Med (2014) 1.11
Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study. Respir Res (2008) 1.11
NF-kappa B and TNF-alpha: a positive autocrine loop in human lung mast cells? J Immunol (2002) 1.11
Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus. J Allergy Clin Immunol (2011) 1.10
Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. J Allergy Clin Immunol (2008) 1.10
The role of Toll-like receptors and related receptors of the innate immune system in asthma. Curr Opin Allergy Clin Immunol (2006) 1.08
TGF-beta isoform release and activation during in vitro bronchial epithelial wound repair. Am J Physiol Lung Cell Mol Physiol (2002) 1.08
ADAM33 expression in asthmatic airways and human embryonic lungs. Am J Respir Crit Care Med (2005) 1.07
Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review. Respirology (2012) 1.07
Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood. PLoS One (2011) 1.05
Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function. Am J Respir Crit Care Med (2004) 1.05
PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. J Allergy Clin Immunol (2009) 1.04
Genomics and the respiratory effects of air pollution exposure. Respirology (2012) 1.03
TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation. J Allergy Clin Immunol (2013) 1.02
An emerging place for lung cancer genomics in 2013. J Thorac Dis (2013) 1.02
IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts. J Allergy Clin Immunol (2006) 1.01
The future of technologies for personalised medicine. N Biotechnol (2012) 1.01
Arg389Gly-beta1-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol. Pharmacogenet Genomics (2007) 1.01
Screening for lung cancer with low-dose computed tomography: a review of current status. J Thorac Dis (2013) 1.01
Airway remodelling in asthma and novel therapy. Asian Pac J Allergy Immunol (2013) 1.00
Respiratory health effects of diesel particulate matter. Respirology (2012) 1.00
Expression profiling identifies genes involved in emphysema severity. Respir Res (2009) 0.98
Genome-wide CpG island methylation analyses in non-small cell lung cancer patients. Carcinogenesis (2012) 0.98
Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation. Am J Respir Cell Mol Biol (2004) 0.98
Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium. Part Fibre Toxicol (2008) 0.98
A new era of targeting the ancient gatekeepers of the immune system: toll-like agonists in the treatment of allergic rhinitis and asthma. Int Arch Allergy Immunol (2014) 0.97
Barrier responses of human bronchial epithelial cells to grass pollen exposure. Eur Respir J (2012) 0.96
The acetaminophen enigma in asthma. Am J Respir Crit Care Med (2011) 0.96
Hypocapnia and asthma: a mechanism for breathing retraining? Chest (2005) 0.95
Reducing agents inhibit rhinovirus-induced up-regulation of the rhinovirus receptor intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells. FASEB J (2002) 0.94
Adenosine receptors as promising therapeutic targets for drug development in chronic airway inflammation. Curr Drug Targets (2006) 0.92
Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction. Pharmacogenet Genomics (2005) 0.92
Whole genome sequencing for lung cancer. J Thorac Dis (2012) 0.91
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response. PLoS One (2012) 0.91
Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease. Am J Respir Med (2002) 0.91
Gas cooking and smoking habits and the risk of childhood and adolescent wheeze. Am J Epidemiol (2005) 0.90
Using genetics to predict the natural history of asthma? J Allergy Clin Immunol (2010) 0.90
Phenotypes and karyotypes of human malignant mesothelioma cell lines. PLoS One (2013) 0.90
Epigenetics of lung cancer. Respirology (2006) 0.90
Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors. PLoS One (2013) 0.89
Priorities for respiratory research in the UK. Thorax (2007) 0.89
Human bronchial fibroblasts express the 5-lipoxygenase pathway. Respir Res (2006) 0.89
Adenosine provocation: a new test for allergic type airway inflammation. Am J Respir Crit Care Med (2002) 0.88
Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma. PLoS One (2012) 0.88
Inflammatory cytokines can enhance CD44-mediated airway epithelial cell adhesion independently of CD44 expression. Am J Physiol Lung Cell Mol Physiol (2003) 0.87
Rhinoviruses in the pathogenesis of asthma: the bronchial epithelium as a major disease target. J Allergy Clin Immunol (2006) 0.87
On the generation of allergic airway diseases: from GM-CSF to Kyoto. Trends Immunol (2002) 0.86
Adamalysins in biology and disease. J Pathol (2009) 0.86
The innate antiviral response upregulates IL-13 receptor α2 in bronchial fibroblasts. J Allergy Clin Immunol (2012) 0.86
Do skin prick and conjunctival provocation tests predict symptom severity in seasonal allergic rhinoconjunctivitis? Clin Exp Allergy (2006) 0.86
Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol (2011) 0.86
MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression. BMC Genomics (2014) 0.85