Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study.

PubWeight™: 1.56‹?› | Rank: Top 4%

🔗 View Article (PMC 2864414)

Published in Carcinogenesis on February 22, 2010

Authors

H Dean Hosgood1, Chin-San Liu, Nathaniel Rothman, Stephanie J Weinstein, Matthew R Bonner, Min Shen, Unhee Lim, Jarmo Virtamo, Wen-ling Cheng, Demetrius Albanes, Qing Lan

Author Affiliations

1: Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8118, MCS 7240, Bethesda, MD 20892-7240, USA. hosgoodd@mail.nih.gov

Articles citing this

Mitochondrial subversion in cancer. Cancer Prev Res (Phila) (2011) 1.54

Circulating tumour markers can define patients with normal colons, benign polyps, and cancers. Br J Cancer (2011) 1.30

Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study. Cancer Epidemiol Biomarkers Prev (2011) 1.20

Mitochondrial copy number is associated with colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2012) 1.19

Mitochondrial DNA copy number and pancreatic cancer in the alpha-tocopherol beta-carotene cancer prevention study. Cancer Prev Res (Phila) (2011) 1.16

Mitochondrial DNA copy number is associated with breast cancer risk. PLoS One (2013) 1.11

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly. Hum Genet (2014) 1.07

Increased mitochondrial DNA copy number in occupations associated with low-dose benzene exposure. Environ Health Perspect (2011) 1.02

The awakening of an advanced malignant cancer: an insult to the mitochondrial genome. Biochim Biophys Acta (2011) 1.02

Variable copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in advanced gastric cancer patients. Diagn Pathol (2013) 0.92

Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China. PLoS One (2012) 0.91

Mitochondria and cancer: past, present, and future. Biomed Res Int (2013) 0.90

Mitochondrial DNA copy number and exposure to polycyclic aromatic hydrocarbons. Cancer Epidemiol Biomarkers Prev (2013) 0.89

A nested case-control study of leukocyte mitochondrial DNA copy number and renal cell carcinoma in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Carcinogenesis (2014) 0.88

Developmental exposure to second-hand smoke increases adult atherogenesis and alters mitochondrial DNA copy number and deletions in apoE(-/-) mice. PLoS One (2013) 0.88

Mitochondrial DNA copy number and future risk of B-cell lymphoma in a nested case-control study in the prospective EPIC cohort. Blood (2014) 0.87

Peripheral blood mitochondrial DNA copy number is associated with prostate cancer risk and tumor burden. PLoS One (2014) 0.87

Mitochondrial DNA copy number in peripheral blood and melanoma risk. PLoS One (2015) 0.86

Molecular oncology focus - is carcinogenesis a 'mitochondriopathy'? J Biomed Sci (2010) 0.85

Mitochondrial DNA copy number in peripheral blood leukocytes and the risk of clear cell renal cell carcinoma. Carcinogenesis (2014) 0.84

Physiology and pathophysiology of mitochondrial DNA. Adv Exp Med Biol (2012) 0.84

Oxidative balance score and oxidative stress biomarkers in a study of Whites, African Americans, and African immigrants. Biomarkers (2014) 0.83

The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease. Hum Genet (2013) 0.83

Peripheral blood mitochondrial DNA copy number, length heteroplasmy and breast cancer risk: a replication study. Carcinogenesis (2015) 0.82

Constitutive mitochondrial DNA copy number in peripheral blood of melanoma families with and without CDKN2A mutations. J Carcinog Mutagen (2014) 0.81

Association of leukocyte mitochondrial DNA content with glioma risk: evidence from a Chinese case-control study. BMC Cancer (2014) 0.79

Pooled analysis of mitochondrial DNA copy number and lung cancer risk in three prospective studies. Cancer Epidemiol Biomarkers Prev (2014) 0.79

Association of leukocyte mitochondrial DNA copy number with colorectal cancer risk: Results from the Shanghai Women's Health Study. Cancer Epidemiol Biomarkers Prev (2014) 0.79

High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients. Oncotarget (2016) 0.78

Mitochondrial DNA copy number and chronic lymphocytic leukemia/small lymphocytic lymphoma risk in two prospective studies. Cancer Epidemiol Biomarkers Prev (2014) 0.78

The role of mitochondria in the development and progression of lung cancer. Comput Struct Biotechnol J (2013) 0.78

High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect. Br J Cancer (2015) 0.77

Mitochondrial-associated metabolic disorders: foundations, pathologies and recent progress. Nutr Metab (Lond) (2013) 0.77

Sex-specific regulation of mitochondrial DNA levels: genome-wide linkage analysis to identify quantitative trait loci. PLoS One (2012) 0.77

Mitochondrial DNA Content as Risk Factor for Bladder Cancer and Its Association with Mitochondrial DNA Polymorphisms. Cancer Prev Res (Phila) (2015) 0.76

High copy number of mitochondrial DNA (mtDNA) predicts good prognosis in glioma patients. Am J Cancer Res (2015) 0.76

Increased leukocyte mitochondrial DNA copy number is associated with oral premalignant lesions: an epidemiology study. Carcinogenesis (2014) 0.76

Oxidative stress, oxidative balance score, and hypertension among a racially diverse population. J Am Soc Hypertens (2015) 0.76

Liver Mitochondrial DNA Copy Number and Deletion Levels May Contribute to Nonalcoholic Fatty Liver Disease Susceptibility. Hepat Mon (2016) 0.75

Mitochondrial DNA Copy Number in Sleep Duration Discordant Monozygotic Twins. Sleep (2015) 0.75

Pre-diagnostic leukocyte mitochondrial DNA copy number and risk of lung cancer. Oncotarget (2016) 0.75

Altered mitochondrial DNA copy number contributes to human cancer risk: evidence from an updated meta-analysis. Sci Rep (2016) 0.75

Pre-diagnostic leukocyte mitochondrial DNA copy number and skin cancer risk. Carcinogenesis (2016) 0.75

Retracted The influence of mtDNA deletion on lung cancer cells under the conditions of hypoxia and irradiation. Lung (2014) 0.75

Mitochondria in chronic obstructive pulmonary disease and lung cancer: where are we now? Biomark Med (2017) 0.75

Articles cited by this

The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance. The ATBC Cancer Prevention Study Group. Ann Epidemiol (1994) 6.47

Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect (1985) 4.73

Lung cancer and indoor air pollution in Xuan Wei, China. Science (1987) 4.36

Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. N Engl J Med (1995) 3.91

Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann N Y Acad Sci (1993) 3.80

Collection of genomic DNA from adults in epidemiological studies by buccal cytobrush and mouthwash. Cancer Epidemiol Biomarkers Prev (2001) 3.40

Mitochondrial DNA sequence variation in human evolution and disease. Proc Natl Acad Sci U S A (1994) 2.96

Mitochondrial DNA in human malignancy. Mutat Res (2001) 2.87

Oxidative stress-related alteration of the copy number of mitochondrial DNA in human leukocytes. Free Radic Res (2003) 2.70

Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells. Biochem J (2000) 2.58

The Finnish Cancer Registry as follow-up source of a large trial cohort--accuracy and delay. Acta Oncol (2002) 2.40

Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci (2005) 1.97

Mitochondrial control of apoptosis: an introduction. Biochem Biophys Res Commun (2003) 1.39

How mitochondrial damage affects cell function. J Biomed Sci (2002) 1.34

Increase of a type of oxidative DNA damage, 8-hydroxyguanine, and its repair activity in human leukocytes by cigarette smoking. Cancer Res (1996) 1.30

Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy. Interact Cardiovasc Thorac Surg (2008) 1.28

Mitochondrial genome damage associated with cigarette smoking. Cancer Res (1996) 1.27

Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes. Free Radic Res Commun (1990) 1.24

The role of oxygen free radicals in occupational and environmental lung diseases. Environ Health Perspect (1997) 1.24

8-Isoprostane as a marker of oxidative stress in nonsymptomatic cigarette smokers and COPD. Eur Respir J (2006) 1.20

Mitochondrial DNA content and lung cancer risk in Xuan Wei, China. Lung Cancer (2008) 1.10

Oxidative stress-induced depolymerization of microtubules and alteration of mitochondrial mass in human cells. Ann N Y Acad Sci (2005) 1.10

Urinary excretion of three nucleic acid oxidation adducts and isoprostane F(2)alpha measured by liquid chromatography-mass spectrometry in smokers, ex-smokers, and nonsmokers. Free Radic Biol Med (2003) 1.04

Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis. Free Radic Biol Med (2007) 0.94

Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells. Eur J Cancer Prev (2009) 0.89

Articles by these authors

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 50.94

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst (2004) 19.00

Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65

Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2008) 13.35

The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43

Genomewide association study of leprosy. N Engl J Med (2009) 8.17

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59

The Shanghai Women's Health Study: rationale, study design, and baseline characteristics. Am J Epidemiol (2005) 6.44

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. Am J Clin Nutr (2009) 5.79

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science (2011) 5.72

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58

The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust. J Natl Cancer Inst (2012) 5.27

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14

NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. Lancet (2005) 5.01

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89

Hematotoxicity in workers exposed to low levels of benzene. Science (2004) 4.19

Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. Lancet Oncol (2006) 4.13

Genome-wide association study of circulating vitamin D levels. Hum Mol Genet (2010) 4.07

Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors. Clin Cancer Res (2008) 4.02

Obesity, diabetes, and risk of prostate cancer: results from the prostate cancer prevention trial. Cancer Epidemiol Biomarkers Prev (2006) 4.02

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93

Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet (2009) 3.76

International patterns and trends in thyroid cancer incidence, 1973-2002. Cancer Causes Control (2008) 3.72

Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol (2008) 3.60

Circulating 25-hydroxyvitamin D and risk of pancreatic cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol (2010) 3.51

SNP500Cancer: a public resource for sequence validation and assay development for genetic variation in candidate genes. Nucleic Acids Res (2004) 3.47

Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer. Am J Epidemiol (2006) 3.41

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol (2012) 3.40

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25

A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res (2007) 3.08

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07

Serum vitamin D concentration and prostate cancer risk: a nested case-control study. J Natl Cancer Inst (2008) 3.04

Counterpoint: bias from population stratification is not a major threat to the validity of conclusions from epidemiological studies of common polymorphisms and cancer. Cancer Epidemiol Biomarkers Prev (2002) 2.99

Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT). J Natl Cancer Inst (2005) 2.99

Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity. J Natl Cancer Inst (2006) 2.97

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96

Body mass and weight change in adults in relation to mortality risk. Am J Epidemiol (2013) 2.87

Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) polymorphisms and risk of non-Hodgkin lymphoma in the InterLymph Consortium. Am J Epidemiol (2010) 2.86

Prospective study of diet and pancreatic cancer in male smokers. Am J Epidemiol (2002) 2.83

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83

Insulin, glucose, insulin resistance, and pancreatic cancer in male smokers. JAMA (2005) 2.71

Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Am J Clin Nutr (2006) 2.64

Shortened telomere length is associated with increased risk of cancer: a meta-analysis. PLoS One (2011) 2.61

A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study. Ann Occup Hyg (2002) 2.60

Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies. Arch Intern Med (2004) 2.60

A prospective nested case-control study of vitamin D status and pancreatic cancer risk in male smokers. Cancer Res (2006) 2.53

Genome-wide association study identifies new prostate cancer susceptibility loci. Hum Mol Genet (2011) 2.51

Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up. JAMA (2003) 2.50

Etiologic heterogeneity among non-Hodgkin lymphoma subtypes. Blood (2008) 2.49

Night-shift work and breast cancer risk in a cohort of Chinese women. Am J Epidemiol (2010) 2.48

Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk. J Natl Cancer Inst (2006) 2.48

A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphoma. Clin Cancer Res (2009) 2.48

Positional accuracy of two methods of geocoding. Epidemiology (2005) 2.47

Variation in KLK genes, prostate-specific antigen and risk of prostate cancer. Nat Genet (2008) 2.45

Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. J Natl Cancer Inst (2006) 2.42

The Finnish Cancer Registry as follow-up source of a large trial cohort--accuracy and delay. Acta Oncol (2002) 2.40