PubRank

Alejandra Bravo

Author PubWeight™ 72.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Engineering modified Bt toxins to counter insect resistance. Science 2007 2.58
2 RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. J Insect Physiol 2010 2.47
3 Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annu Rev Genet 2003 2.39
4 Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection. FEMS Microbiol Rev 2012 1.88
5 Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin. FEBS Lett 2002 1.86
6 Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor. Proc Natl Acad Sci U S A 2005 1.72
7 A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae. Biochem J 2006 1.56
8 Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation. J Biol Chem 2002 1.38
9 Single amino acid mutations in the cadherin receptor from Heliothis virescens affect its toxin binding ability to Cry1A toxins. J Biol Chem 2004 1.35
10 Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping pong" binding mechanism with Manduca sexta aminopeptidase-N and cadherin receptors. J Biol Chem 2009 1.32
11 Diversity of Bacillus thuringiensis strains from Latin America with insecticidal activity against different mosquito species. Appl Environ Microbiol 2003 1.30
12 Role of alkaline phosphatase from Manduca sexta in the mechanism of action of Bacillus thuringiensis Cry1Ab toxin. J Biol Chem 2010 1.29
13 Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae. J Biol Chem 2007 1.27
14 Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta. J Biol Chem 2006 1.24
15 Structural changes of the Cry1Ac oligomeric pre-pore from bacillus thuringiensis induced by N-acetylgalactosamine facilitates toxin membrane insertion. Biochemistry 2006 1.23
16 Molecular basis for Bacillus thuringiensis Cry1Ab toxin specificity: two structural determinants in the Manduca sexta Bt-R1 receptor interact with loops alpha-8 and 2 in domain II of Cy1Ab toxin. Biochemistry 2003 1.22
17 Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis. Biochem J 2009 1.19
18 Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance. Nat Biotechnol 2011 1.19
19 Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure. Cell Microbiol 2007 1.17
20 The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis. Insect Biochem Mol Biol 2009 1.16
21 Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop alpha-8 of domain II. FEBS Lett 2005 1.14
22 Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation. Peptides 2008 1.13
23 Hydropathic complementarity determines interaction of epitope (869)HITDTNNK(876) in Manduca sexta Bt-R(1) receptor with loop 2 of domain II of Bacillus thuringiensis Cry1A toxins. J Biol Chem 2002 1.10
24 Mode of action of mosquitocidal Bacillus thuringiensis toxins. Toxicon 2006 1.09
25 Tryptophan spectroscopy studies and black lipid bilayer analysis indicate that the oligomeric structure of Cry1Ab toxin from Bacillus thuringiensis is the membrane-insertion intermediate. Biochemistry 2004 1.00
26 Pore formation by Cry toxins. Adv Exp Med Biol 2010 1.00
27 Cadherin, alkaline phosphatase, and aminopeptidase N as receptors of Cry11Ba toxin from Bacillus thuringiensis subsp. jegathesan in Aedes aegypti. Appl Environ Microbiol 2010 0.98
28 An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor. Biochem Biophys Res Commun 2007 0.97
29 Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism. Peptides 2010 0.96
30 Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects. Biochim Biophys Acta 2009 0.95
31 A Bacillus thuringiensis S-layer protein involved in toxicity against Epilachna varivestis (Coleoptera: Coccinellidae). Appl Environ Microbiol 2006 0.95
32 Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti. Biochemistry 2009 0.95
33 Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and membrane-inserted pore channel. J Biol Chem 2004 0.95
34 Cyt toxins produced by Bacillus thuringiensis: a protein fold conserved in several pathogenic microorganisms. Peptides 2012 0.95
35 Role of MAPK p38 in the cellular responses to pore-forming toxins. Peptides 2010 0.93
36 Differential role of Manduca sexta aminopeptidase-N and alkaline phosphatase in the mode of action of Cry1Aa, Cry1Ab, and Cry1Ac toxins from Bacillus thuringiensis. Appl Environ Microbiol 2013 0.93
37 Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage. J Invertebr Pathol 2006 0.93
38 A system for the directed evolution of the insecticidal protein from Bacillus thuringiensis. Mol Biotechnol 2007 0.92
39 Genetic variability of Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) populations from Latin America is associated with variations in susceptibility to Bacillus thuringiensis cry toxins. Appl Environ Microbiol 2006 0.92
40 Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity. PLoS One 2009 0.91
41 An alpha-amylase is a novel receptor for Bacillus thuringiensis ssp. israelensis Cry4Ba and Cry11Aa toxins in the malaria vector mosquito Anopheles albimanus (Diptera: Culicidae). Environ Microbiol 2009 0.90
42 Multiple receptors as targets of Cry toxins in mosquitoes. J Agric Food Chem 2011 0.90
43 Modified Bacillus thuringiensis toxins and a hybrid B. thuringiensis strain counter greenhouse-selected resistance in Trichoplusia ni. Appl Environ Microbiol 2009 0.89
44 Comparative proteomic analysis of Aedes aegypti larval midgut after intoxication with Cry11Aa toxin from Bacillus thuringiensis. PLoS One 2012 0.89
45 Midgut GPI-anchored proteins with alkaline phosphatase activity from the cotton boll weevil (Anthonomus grandis) are putative receptors for the Cry1B protein of Bacillus thuringiensis. Insect Biochem Mol Biol 2010 0.89
46 Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anopheles albimanus. J Invertebr Pathol 2010 0.88
47 Cadherin binding is not a limiting step for Bacillus thuringiensis subsp. israelensis Cry4Ba toxicity to Aedes aegypti larvae. Biochem J 2012 0.87
48 Defense and death responses to pore forming toxins. Biotechnol Genet Eng Rev 2010 0.85
49 Efficacy of genetically modified Bt toxins alone and in combinations against pink bollworm resistant to Cry1Ac and Cry2Ab. PLoS One 2013 0.84
50 The amino- and carboxyl-terminal fragments of the Bacillus thuringensis Cyt1Aa toxin have differential roles in toxin oligomerization and pore formation. Biochemistry 2010 0.84
51 Oligomerization of Cry11Aa from Bacillus thuringiensis has an important role in toxicity against Aedes aegypti. Appl Environ Microbiol 2009 0.84
52 Aedes aegypti alkaline phosphatase ALP1 is a functional receptor of Bacillus thuringiensis Cry4Ba and Cry11Aa toxins. Insect Biochem Mol Biol 2012 0.83
53 Identification of distinct K+ channels in mouse spermatogenic cells and sperm. Zygote 2002 0.83
54 Role of tryptophan residues in toxicity of Cry1Ab toxin from Bacillus thuringiensis. Appl Environ Microbiol 2006 0.83
55 Assessment of cry1 gene contents of Bacillus thuringiensis strains by use of DNA microarrays. Appl Environ Microbiol 2005 0.83
56 Structural and functional analysis of the pre-pore and membrane-inserted pore of Cry1Ab toxin. J Invertebr Pathol 2006 0.82
57 Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest hetero-oligomer formation among different Cry toxins. PLoS One 2011 0.81
58 Role of UPR pathway in defense response of Aedes aegypti against Cry11Aa toxin from Bacillus thuringiensis. Int J Mol Sci 2013 0.81
59 Domains II and III of Bacillus thuringiensis Cry1Ab toxin remain exposed to the solvent after insertion of part of domain I into the membrane. J Biol Chem 2011 0.80
60 A Tenebrio molitor GPI-anchored alkaline phosphatase is involved in binding of Bacillus thuringiensis Cry3Aa to brush border membrane vesicles. Peptides 2012 0.80
61 Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins. Peptides 2007 0.79
62 Variability of Bacillus thuringiensis strains by ERIC-PCR and biofilm formation. Curr Microbiol 2014 0.78
63 Use of Bacillus thuringiensis toxin as an alternative method of control against Haemonchus contortus. Ann N Y Acad Sci 2006 0.78
64 Tobacco plants expressing the Cry1AbMod toxin suppress tolerance to Cry1Ab toxin of Manduca sexta cadherin-silenced larvae. Insect Biochem Mol Biol 2011 0.78
65 Assembling of Holotrichia parallela (dark black chafer) midgut tissue transcriptome and identification of midgut proteins that bind to Cry8Ea toxin from Bacillus thuringiensis. Appl Microbiol Biotechnol 2015 0.77
66 Toxicity of Bacillus thuringiensis delta-endotoxins against bean shoot borer (Epinotia aporema Wals.) larvae, a major soybean pest in Argentina. J Invertebr Pathol 2006 0.76
67 Bt toxin not guilty by association. Nat Biotechnol 2005 0.75
68 Efficient production of Bacillus thuringiensis Cry1AMod toxins under regulation of cry3Aa promoter and single cysteine mutations in the protoxin region. Appl Environ Microbiol 2013 0.75
69 [Microorganisms in the biological control of insects and phytopathogens]. Rev Latinoam Microbiol 2007 0.75
70 Cryptic endotoxic nature of Bacillus thuringiensis Cry1Ab insecticidal crystal protein. FEBS Lett 2004 0.75