Published in Annu Rev Immunol on January 01, 2010
Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol (2014) 2.88
Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity (2011) 2.61
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. J Exp Med (2012) 1.90
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nat Immunol (2012) 1.81
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol (2013) 1.74
IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection. Nat Immunol (2015) 1.53
Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Proc Natl Acad Sci U S A (2012) 1.26
Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation. J Biol Chem (2011) 1.21
Clinical implications of the molecular genetics of chronic lymphocytic leukemia. Haematologica (2013) 1.17
Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia. Leukemia (2013) 1.08
T cell lineage commitment: identity and renunciation. J Immunol (2011) 1.01
Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions. Blood (2011) 0.99
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med (2014) 0.99
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia. Haematologica (2014) 0.94
A bright single-cell resolution live imaging reporter of Notch signaling in the mouse. BMC Dev Biol (2013) 0.94
Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells. Breast Cancer Res Treat (2012) 0.93
Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease. Blood (2011) 0.91
Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. Nat Immunol (2015) 0.91
The truncate mutation of Notch2 enhances cell proliferation through activating the NF-κB signal pathway in the diffuse large B-cell lymphomas. PLoS One (2014) 0.90
NOTCH1 mutations associate with low CD20 level in chronic lymphocytic leukemia: evidence for a NOTCH1 mutation-driven epigenetic dysregulation. Leukemia (2015) 0.90
Recombination signal binding protein for Ig-κJ region regulates juxtaglomerular cell phenotype by activating the myo-endocrine program and suppressing ectopic gene expression. J Am Soc Nephrol (2014) 0.87
Bone marrow-derived IL-13Rα1-positive thymic progenitors are restricted to the myeloid lineage. J Immunol (2012) 0.86
HEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticity. Clin Dev Immunol (2012) 0.86
Engagement of activated Notch signalling in collagen II-specific T helper type 1 (Th1)- and Th17-type expansion involving Notch3 and Delta-like1. Clin Exp Immunol (2011) 0.84
SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. PLoS Genet (2014) 0.84
Blockade of Notch ligand δ1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation. J Immunol (2011) 0.84
Lunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo. J Immunol (2010) 0.83
Jagged1 and Notch1 help edit M cell patterning in Peyer's patch follicle epithelium. Dev Comp Immunol (2012) 0.82
Mind bomb-1 in dendritic cells is specifically required for Notch-mediated T helper type 2 differentiation. PLoS One (2012) 0.82
The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus. Front Immunol (2015) 0.81
Role of Notch signaling in regulating innate immunity and inflammation in health and disease. Protein Cell (2016) 0.81
The NOTCH pathway contributes to cell fate decision in myelopoiesis. Haematologica (2011) 0.80
Ferulic Acid Induces Th1 Responses by Modulating the Function of Dendritic Cells and Ameliorates Th2-Mediated Allergic Airway Inflammation in Mice. Evid Based Complement Alternat Med (2015) 0.80
Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment. Cold Spring Harb Symp Quant Biol (2013) 0.79
Notch ligand delta-like 4-pretreated dendritic cells alleviate allergic airway responses by enhancing IL-10 production. PLoS One (2013) 0.79
Characterization of N- and O-linked glycosylation changes in milk of the tammar wallaby (Macropus eugenii) over lactation. Glycoconj J (2012) 0.78
Constitutive expression of genes encoding notch receptors and ligands in developing lymphocytes, nTreg cells and dendritic cells in the human thymus. Results Immunol (2016) 0.78
Microbial heat shock protein 65 attenuates airway hyperresponsiveness and inflammation by modulating the function of dendritic cells. J Immunol (2012) 0.78
Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E2-induced regulatory T cell expansion. Sci Rep (2016) 0.78
Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development. J Immunol (2015) 0.78
Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling. Front Cell Infect Microbiol (2012) 0.78
Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis. PLoS One (2011) 0.78
Gene profiling reveals association between altered Wnt signaling and loss of T-cell potential with age in human hematopoietic stem cells. Aging Cell (2014) 0.78
The spinal notch signaling pathway plays a pivotal role in the development of neuropathic pain. Mol Brain (2012) 0.77
STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease. J Immunol (2013) 0.77
RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes. Protein Cell (2016) 0.77
Betaglycan (TβRIII) is expressed in the thymus and regulates T cell development by protecting thymocytes from apoptosis. PLoS One (2012) 0.77
Notch-Mediated Cell Adhesion. Biology (Basel) (2016) 0.76
Expanding role of delta-like 4 mediated notch signaling in cardiovascular and metabolic diseases. Circ J (2013) 0.76
Possible involvement of Notch signaling in the pathogenesis of Buerger's disease. Surg Today (2013) 0.76
Illegitimate V(D)J recombination-mediated deletions in Notch1 and Bcl11b are not sufficient for extensive clonal expansion and show minimal age or sex bias in frequency or junctional processing. Mutat Res (2014) 0.76
Expression of Notch signaling components in cutaneous foreign body and sarcoidal granulomas and fusing macrophages. Am J Dermatopathol (2014) 0.75
Notch signalling suppresses regulatory T-cell function in murine experimental autoimmune uveitis. Immunology (2016) 0.75
Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner. Sci Rep (2016) 0.75
Notch Stimulates Both Self-Renewal and Lineage Plasticity in a Subset of Murine CD9High Committed Megakaryocytic Progenitors. PLoS One (2016) 0.75
(-)-Epigallocatechin Gallate Targets Notch to Attenuate the Inflammatory Response in the Immediate Early Stage in Human Macrophages. Front Immunol (2017) 0.75
Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis. Br J Psychiatry (2016) 0.75
Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier? Front Immunol (2017) 0.75
Delta-Like-1 Changes the Immunomodulatory Property of OP9 Cells. Stem Cells Int (2015) 0.75
Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology. BMC Genomics (2016) 0.75
ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. J Immunol (2017) 0.75
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development. Nat Immunol (2005) 2.19
Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches. Immunity (2009) 2.03
The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. Cancer Cell (2003) 1.90
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol (2013) 1.87
Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood (2012) 1.81
Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med (2009) 1.80
Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors. Cancer Res (2004) 1.80
Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches. Nat Immunol (2006) 1.57
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. Cancer Cell (2012) 1.44
Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions. Immunol Rev (2006) 1.20
ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection. Immunol Rev (2006) 1.15
ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes. Blood (2006) 1.13
Chromosomal reinsertion of broken RSS ends during T cell development. J Exp Med (2007) 1.03
Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions. Blood (2011) 0.99
Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification. J Immunol (2002) 0.98
Regulation of Notch signaling during T- and B-cell development by O-fucose glycans. Immunol Rev (2009) 0.97
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival. PLoS One (2012) 0.96
Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors. Blood (2010) 0.88
p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc. Mol Cancer Res (2006) 0.86
Fine-tuning Notch1 activation by endocytosis and glycosylation. Semin Immunol (2003) 0.84
Lunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo. J Immunol (2010) 0.83
Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis. PLoS One (2011) 0.78
STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease. J Immunol (2013) 0.77
Marking HIV. Nat Immunol (2017) 0.75
Neuroimmune interactions: ILC3s. Nat Immunol (2017) 0.75
Atherosclerosis-prone HSCs. Nat Immunol (2017) 0.75
Hypoxic germinal centers. Nat Immunol (2016) 0.75
Macrophage dynamics. Nat Immunol (2017) 0.75
Regulating hair growth. Nat Immunol (2017) 0.75
Neuroimmune interactions: astrocytes. Nat Immunol (2017) 0.75
The interferon signature. Nat Immunol (2017) 0.75
Precursor privileges. Nat Immunol (2016) 0.75
Importing material. Nat Immunol (2017) 0.75
Exit from the liver. Nat Immunol (2016) 0.75
Counting HSCs. Nat Immunol (2016) 0.75
TLR4 in lung regeneration. Nat Immunol (2016) 0.75
Non-inflammatory IFN. Nat Immunol (2017) 0.75
Sensing cholesterol dynamics. Nat Immunol (2016) 0.75
Acetate for memory. Nat Immunol (2016) 0.75
Microbe-activity sensor. Nat Immunol (2016) 0.75
Compartmentalized selection. Nat Immunol (2016) 0.75
Insulin resistance: old or obese? Nat Immunol (2015) 0.75
MALT1 regulates LUBAC. Nat Immunol (2015) 0.75
Pathogenicity control. Nat Immunol (2015) 0.75
Apoptosis footprint. Nat Immunol (2016) 0.75
Deacetylation for viral sensing. Nat Immunol (2016) 0.75
Fasting fights leukemia. Nat Immunol (2017) 0.75
Of mitochondria: part II. Nat Immunol (2016) 0.75
Preserving intestinal stem cells. Nat Immunol (2015) 0.75
Old fat macrophages. Nat Immunol (2017) 0.75
Beyond systems analysis. Nat Immunol (2016) 0.75
Of mitochondria: part I. Nat Immunol (2016) 0.75
Neurodegenerative signature. Nat Immunol (2017) 0.75
CMTM6 controls PD-L1. Nat Immunol (2017) 0.75
Epigenetic silencing in tumors. Nat Immunol (2015) 0.75
Platelet bias with age. Nat Immunol (2016) 0.75
The scorpion sting. Nat Immunol (2016) 0.75
Inflammation memory. Nat Immunol (2016) 0.75
Alzheimer's disease microglia. Nat Immunol (2017) 0.75
Macrophage core program. Nat Immunol (2016) 0.75
The survival factor. Nat Immunol (2016) 0.75
Enchained growth. Nat Immunol (2017) 0.75
HIV-1 trans-infection. Nat Immunol (2016) 0.75
Corrigendum: Notch signal strength controls cell fate in the haemogenic endothelium. Nat Commun (2016) 0.75
The tryptophan link. Nat Immunol (2016) 0.75
Drivers of metastasis. Nat Immunol (2016) 0.75
Regulatory ILCs. Nat Immunol (2017) 0.75
Gut macrophage specialization. Nat Immunol (2016) 0.75
The protective crypt. Nat Immunol (2016) 0.75
Aging neutrophils. Nat Immunol (2015) 0.75
Fertilization and nucleic acid sensing. Nat Immunol (2017) 0.75