Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 26921237)

Published in BMC Genomics on February 27, 2016

Authors

Kailai Wang1, Carmelo del Castillo2, Erwan Corre3, Emmanuelle Pales Espinosa4, Bassem Allam5

Author Affiliations

1: School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794-5000, USA. kailai.wang@stonybrook.edu.
2: School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794-5000, USA. chiandc@gmail.com.
3: Analyses and Bioinformatics for Marine Science, Station Biologique de Roscoff, 29688, Roscoff Cedex, France. corre@sb-roscoff.fr.
4: School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794-5000, USA. Emmanuelle.Palesespinosa@stonybrook.edu.
5: School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794-5000, USA. Bassem.Allam@stonybrook.edu.

Articles citing this

Comparative immunogenomics of molluscs. Dev Comp Immunol (2017) 0.75

Articles cited by this

(truncated to the top 100)

Differential expression analysis for sequence count data. Genome Biol (2010) 64.56

Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nat Biotechnol (2011) 53.86

KAAS: an automatic genome annotation and pathway reconstruction server. Nucleic Acids Res (2007) 29.46

Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput Biol (2012) 6.38

Pattern recognition receptors: doubling up for the innate immune response. Cell (2002) 4.84

A direct role for dual oxidase in Drosophila gut immunity. Science (2005) 4.24

GAGE: generally applicable gene set enrichment for pathway analysis. BMC Bioinformatics (2009) 3.86

WNT signalling in the immune system: WNT is spreading its wings. Nat Rev Immunol (2008) 3.46

The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol Rev (2007) 3.33

Signaling in innate immunity and inflammation. Cold Spring Harb Perspect Biol (2012) 3.11

Role of heat shock proteins in protection from and pathogenesis of infectious diseases. Clin Microbiol Rev (1999) 2.69

Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to Tobacco mosaic virus. Plant Cell (2002) 2.21

Genomic insights into the immune system of the sea urchin. Science (2006) 2.20

Granulomatous inflammation--a review. J Clin Pathol (1983) 2.15

Extensive transcriptional heterogeneity revealed by isoform profiling. Nature (2013) 2.14

MAP kinase phosphatases. Genome Biol (2002) 1.88

Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics. FASEB J (1992) 1.86

Alpha-macroglobulins: structure, shape, and mechanism of proteinase complex formation. J Biol Chem (1989) 1.84

Selectin-carbohydrate interactions and the initiation of the inflammatory response. Annu Rev Biochem (1995) 1.77

Metalloproteinases and their natural inhibitors in inflammation and immunity. Nat Rev Immunol (2013) 1.77

Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis. Immunity (2012) 1.75

Functions of notch signaling in the immune system: consensus and controversies. Annu Rev Immunol (2010) 1.68

Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur J Immunol (2008) 1.68

Whole transcriptome analysis of the coral Acropora millepora reveals complex responses to CO₂-driven acidification during the initiation of calcification. Mol Ecol (2012) 1.66

Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo. J Immunol (1999) 1.65

Crosstalk in the responses to abiotic and biotic stresses in Arabidopsis: analysis of gene expression in cytochrome P450 gene superfamily by cDNA microarray. Plant Mol Biol (2004) 1.63

Influence of the mannose receptor in host immune responses. Immunobiology (2009) 1.58

EST clustering error evaluation and correction. Bioinformatics (2004) 1.54

Heat shock proteins (chaperones) in fish and shellfish and their potential role in relation to fish health: a review. J Fish Dis (2010) 1.46

Iron-withholding strategy in innate immunity. Immunobiology (2006) 1.45

Heat shock proteins: linking danger and pathogen recognition. Med Microbiol Immunol (2007) 1.45

The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis. J Cell Sci (2002) 1.44

WW domain-containing oxidoreductase: a candidate tumor suppressor. Trends Mol Med (2006) 1.44

Wnt signaling induces epithelial differentiation during cutaneous wound healing. BMC Cell Biol (2006) 1.39

Dual oxidase in mucosal immunity and host-microbe homeostasis. Trends Immunol (2010) 1.36

Tissue-specific transcriptomics of the exotic invasive insect pest emerald ash borer (Agrilus planipennis). PLoS One (2010) 1.36

Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a. J Mol Cell Cardiol (2008) 1.35

Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling. J Biol Chem (2003) 1.35

Bacteria-hemocyte interactions and phagocytosis in marine bivalves. Microsc Res Tech (2002) 1.34

Production of Schistosoma mansoni daughter sporocysts from mother sporocysts maintained in synxenic culture with Biomphalaria glabrata embryonic (Bge) cells. J Parasitol (1995) 1.30

Pattern recognition receptors in the immune response against dying cells. Curr Opin Immunol (2008) 1.29

Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity. J Leukoc Biol (2008) 1.28

The role of scavenger receptors in pathogen recognition and innate immunity. Immunobiology (2004) 1.27

Identification and removal of ribosomal RNA sequences from metatranscriptomes. Bioinformatics (2011) 1.25

Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation. J Biol Chem (2011) 1.21

Conserved domains of the class A scavenger receptors: evolution and function. Immunol Rev (2009) 1.20

Differential transcriptomic responses of Biomphalaria glabrata (Gastropoda, Mollusca) to bacteria and metazoan parasites, Schistosoma mansoni and Echinostoma paraensei (Digenea, Platyhelminthes). Mol Immunol (2009) 1.19

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane. Blood (2011) 1.16

A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite model. PLoS Negl Trop Dis (2010) 1.16

Immune response from a resource allocation perspective. Front Genet (2012) 1.14

Proteases and protease inhibitors: a balance of activities in host-pathogen interaction. Immunobiology (2006) 1.08

Integrin signalling and function in immune cells. Immunology (2012) 1.07

Integrative study of physiological changes associated with bacterial infection in Pacific oyster larvae. PLoS One (2013) 1.07

Massively parallel RNA sequencing identifies a complex immune gene repertoire in the lophotrochozoan Mytilus edulis. PLoS One (2012) 1.07

Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins. Biochim Biophys Acta (2011) 1.06

The evolution of the Wnt pathway. Cold Spring Harb Perspect Biol (2012) 1.06

Drosophila C-type lectins enhance cellular encapsulation. Mol Immunol (2007) 1.06

Role of G protein-coupled receptors in inflammation. Acta Pharmacol Sin (2012) 1.05

Transcriptomic responses to salinity stress in the Pacific oyster Crassostrea gigas. PLoS One (2012) 1.04

RNA-seq profiles of immune related genes in the staghorn coral Acropora cervicornis infected with white band disease. PLoS One (2013) 1.01

Neutrophil serine proteases: mediators of innate immune responses. Curr Opin Hematol (2011) 1.00

Regulation of immune function by G protein-coupled receptors, trimeric G proteins, and RGS proteins. Prog Mol Biol Transl Sci (2009) 0.95

Toll-8/Tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium. PLoS Pathog (2011) 0.95

Transcriptomics of in vitro immune-stimulated hemocytes from the Manila clam Ruditapes philippinarum using high-throughput sequencing. PLoS One (2012) 0.92

The putative sponge aggregation receptor. Isolation and characterization of a molecule composed of scavenger receptor cysteine-rich domains and short consensus repeats. J Cell Sci (1998) 0.92

Regulation of granulomatous inflammation in experimental models of schistosomiasis. Infect Immun (2004) 0.92

Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi. BMC Evol Biol (2012) 0.91

An Mpeg (macrophage expressed gene) from the Pacific oyster Crassostrea gigas: molecular characterization and gene expression. Fish Shellfish Immunol (2011) 0.91

Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase. J Mol Cell Cardiol (2010) 0.91

Wild skylarks seasonally modulate energy budgets but maintain energetically costly inflammatory immune responses throughout the annual cycle. PLoS One (2012) 0.91

Gonad transcriptome analysis of pearl oyster Pinctada margaritifera: identification of potential sex differentiation and sex determining genes. BMC Genomics (2014) 0.90

Molecular cloning and expression of a Toll receptor gene homologue from Zhikong Scallop, Chlamys farreri. Fish Shellfish Immunol (2006) 0.90

Identification and expression of differentially expressed genes in the hard clam, Mercenaria mercenaria, in response to quahog parasite unknown (QPX). BMC Genomics (2009) 0.88

Universal stress proteins are important for oxidative and acid stress resistance and growth of Listeria monocytogenes EGD-e in vitro and in vivo. PLoS One (2011) 0.87

Toll signal transduction pathway in bivalves: complete cds of intermediate elements and related gene transcription levels in hemocytes of immune stimulated Mytilus galloprovincialis. Dev Comp Immunol (2014) 0.86

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper. Biosci Rep (2013) 0.86

Trade-off between immune stimulation and expression of storage protein genes. Arch Insect Biochem Physiol (2009) 0.86

Granulomatous inflammation. Rev Inst Med Trop Sao Paulo (1995) 0.86

Cellular receptors and signal transduction in molluscan hemocytes: connections with the innate immune system of vertebrates. Integr Comp Biol (2003) 0.86

The COP9 signalosome: its regulation of cullin-based E3 ubiquitin ligases and role in photomorphogenesis. Plant Physiol (2012) 0.85

Inhibitors of apoptosis proteins (IAPs) are required for effective T-cell expansion/survival during antiviral immunity in mice. Blood (2013) 0.85

Parasitic infections: a role for C-type lectins receptors. Biomed Res Int (2013) 0.83

Effects of temperature on hard clam (Mercenaria mercenaria) immunity and QPX (Quahog Parasite Unknown) disease development: II. Defense parameters. J Invertebr Pathol (2010) 0.83

Gene expression analysis of clams Ruditapes philippinarum and Ruditapes decussatus following bacterial infection yields molecular insights into pathogen resistance and immunity. Dev Comp Immunol (2011) 0.83

An ancient C-type lectin in Chlamys farreri (CfLec-2) that mediate pathogen recognition and cellular adhesion. Dev Comp Immunol (2010) 0.83

Prevalence and distribution of QPX, Quahog Parasite Unknown, in hard clams Mercenaria mercenaria in Virginia, USA. Dis Aquat Organ (1998) 0.83

The oxidative environment: a mediator of interspecies communication that drives symbiosis evolution. Proc Biol Sci (2014) 0.83

Deep transcriptome sequencing of Pecten maximus hemocytes: a genomic resource for bivalve immunology. Fish Shellfish Immunol (2014) 0.83

Host-parasite interactions: Marine bivalve molluscs and protozoan parasites, Perkinsus species. J Invertebr Pathol (2013) 0.82

Observations of a Protistan Disease Similar to QPX in Mercenaria mercenaria (Hard Clams) from the Coast of Massachusetts J Invertebr Pathol (1998) 0.82

Polymorphism in a serine protease inhibitor gene and its association with disease resistance in the eastern oyster (Crassostrea virginica Gmelin). Fish Shellfish Immunol (2011) 0.81

[Reactive oxygen species and defense mechanisms in marine bivalves]. C R Acad Sci III (1996) 0.81

Mechanisms and immunological roles of apoptosis in molluscs. Curr Pharm Des (2008) 0.81

Environmental distribution and persistence of Quahog Parasite Unknown (QPX). Dis Aquat Organ (2008) 0.81

A novel slow-tight binding serine protease inhibitor from eastern oyster (Crassostrea virginica) plasma inhibits perkinsin, the major extracellular protease of the oyster protozoan parasite Perkinsus marinus. Comp Biochem Physiol B Biochem Mol Biol (2006) 0.80

Differential gene expression of gamma-actin, Toll-like receptor 2 (TLR-2) and interleukin-1 receptor-associated kinase 4 (IRAK-4) in Mya arenaria haemocytes induced by in vivo infections with two Vibrio splendidus strains. Dev Comp Immunol (2010) 0.80

A novel scavenger receptor-cysteine-rich (SRCR) domain containing scavenger receptor identified from mollusk mediated PAMP recognition and binding. Dev Comp Immunol (2010) 0.80

Serine protease inhibitor cvSI-1 potential role in the eastern oyster host defense against the protozoan parasite Perkinsus marinus. Dev Comp Immunol (2009) 0.80

Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation. Aquat Toxicol (2010) 0.79

Mutation in promoter region of a serine protease inhibitor confers Perkinsus marinus resistance in the eastern oyster (Crassostrea virginica). Fish Shellfish Immunol (2012) 0.79