Published in J Immunol on March 01, 2010
Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions. Cell Commun Signal (2011) 1.09
B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2. Proc Natl Acad Sci U S A (2010) 1.08
Swiprosin-1 modulates actin dynamics by regulating the F-actin accessibility to cofilin. Cell Mol Life Sci (2013) 0.93
Swiprosin-1 is a novel actin bundling protein that regulates cell spreading and migration. PLoS One (2013) 0.92
EFhd2 is a novel amyloid protein associated with pathological tau in Alzheimer's disease. J Neurochem (2013) 0.89
Functional and structural analysis of the conserved EFhd2 protein. Protein Pept Lett (2013) 0.89
The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons. PLoS One (2014) 0.82
Cdk5 phosphorylation of EFhd2 at S74 affects its calcium binding activity. Protein Sci (2014) 0.80
The calcium-binding protein EFhd2 modulates synapse formation in vitro and is linked to human dementia. J Neuropathol Exp Neurol (2014) 0.78
Monoclonal antibodies to discriminate the EF hand containing calcium binding adaptor proteins EFhd1 and EFhd2. Monoclon Antib Immunodiagn Immunother (2013) 0.78
The adaptor protein Swiprosin-1/EFhd2 is dispensable for platelet function in mice. PLoS One (2014) 0.76
EFhd2, a Protein Linked to Alzheimer's Disease and Other Neurological Disorders. Front Neurosci (2016) 0.76
Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system. Biochem J (2016) 0.76
Low level of swiprosin-1/EFhd2 in vestibular nuclei of spontaneously hypersensitive motion sickness mice. Sci Rep (2017) 0.75
Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1. Sci Rep (2016) 0.75
Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns. Blood (2012) 3.63
Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus. Nat Med (2013) 2.93
hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay. Mol Cell Biol (2006) 2.69
Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition. Cancer Res (2007) 2.50
The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur J Immunol (2004) 2.38
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity (2007) 2.28
Serum microRNAs as powerful cancer biomarkers. Biochim Biophys Acta (2010) 1.98
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2. Structure (2009) 1.89
Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function. J Exp Med (2009) 1.80
IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta. J Exp Med (2007) 1.75
Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance. J Immunol (2006) 1.62
Cutting edge: signaling and cell surface expression of a mu H chain in the absence of lambda 5: a paradigm revisited. J Immunol (2003) 1.57
BCL6 is critical for the development of a diverse primary B cell repertoire. J Exp Med (2010) 1.56
Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus. Rheumatology (Oxford) (2010) 1.53
Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42. Blood (2013) 1.52
Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population. Nat Immunol (2007) 1.48
Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76. EMBO J (2003) 1.38
Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production. J Exp Med (2006) 1.36
Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes. J Cell Biol (2008) 1.35
The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound. J Exp Med (2002) 1.35
Reduction of marginal zone B cells in CD22-deficient mice. Eur J Immunol (2002) 1.31
CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity. J Immunol (2010) 1.29
The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells. J Immunol (2003) 1.25
Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix. J Biol Chem (2004) 1.21
GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol (2013) 1.19
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck. Biochemistry (2002) 1.17
Human INT6/eIF3e is required for nonsense-mediated mRNA decay. EMBO Rep (2007) 1.16
Emerging roles of Abl family tyrosine kinases in microbial pathogenesis. Trends Biochem Sci (2008) 1.16
NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network. J Exp Med (2011) 1.15
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci U S A (2008) 1.13
A single DH gene segment creates its own unique CDR-H3 repertoire and is sufficient for B cell development and immune function. J Immunol (2005) 1.13
Lipid rafts associate with intracellular B cell receptors and exhibit a B cell stage-specific protein composition. J Immunol (2005) 1.12
Regulation of B cell development and B cell signalling by CD22 and its ligands alpha2,6-linked sialic acids. Int Immunol (2006) 1.11
Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice. J Clin Invest (2013) 1.11
Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions. Cell Commun Signal (2011) 1.09
Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system. Brain (2008) 1.08
B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2. Proc Natl Acad Sci U S A (2010) 1.08
Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors. BMC Dev Biol (2008) 1.08
Regulation of repertoire development through genetic control of DH reading frame preference. J Immunol (2008) 1.06
Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells. Cell Commun Signal (2008) 1.05
Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation. Cancer Res (2009) 1.05
Regulation of B cell functions by the sialic acid-binding receptors siglec-G and CD22. Front Immunol (2012) 1.04
PI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitors. BMC Biol (2004) 1.04
Transcriptome analysis in primary B lymphoid precursors following induction of the pre-B cell receptor. Mol Immunol (2007) 1.03
Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells. Cell Commun Signal (2008) 1.03
B cell-specific transgenic expression of Bcl2 rescues early B lymphopoiesis but not B cell responses in BOB.1/OBF.1-deficient mice. J Exp Med (2003) 1.02
The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal. Structure (2006) 1.01
BOB.1/OBF.1 deficiency affects marginal-zone B-cell compartment. Mol Cell Biol (2002) 1.01
Evidence of abortive plasma cell differentiation in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma. Hematol Oncol (2005) 1.00
Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling. EMBO J (2011) 1.00
Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir. Proc Natl Acad Sci U S A (2009) 0.99
Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers. Cell Commun Signal (2011) 0.99
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. Eur J Immunol (2015) 0.98
HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing. Nucleic Acids Res (2012) 0.98
Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis. J Allergy Clin Immunol (2007) 0.98
Interaction of murine precursor B cell receptor with stroma cells is controlled by the unique tail of lambda 5 and stroma cell-associated heparan sulfate. J Immunol (2003) 0.97
Amino acid residues constituting the agonist binding site of the human P2X3 receptor. J Biol Chem (2010) 0.96
Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes. Eur J Immunol (2006) 0.96
Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies. Mol Biosyst (2011) 0.95
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer. Mol Cell Proteomics (2011) 0.95
Differentially regulated expression and function of CD22 in activated B-1 and B-2 lymphocytes. J Immunol (2002) 0.95
The B cell receptor-induced calcium flux involves a calcium mediated positive feedback loop. Cell Calcium (2012) 0.94
ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63. Proc Natl Acad Sci U S A (2013) 0.94
The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes. Diabetes (2013) 0.93
Transitional and marginal zone B cells have a high proportion of unmasked CD22: implications for BCR signaling. Int Immunol (2003) 0.93
B cell-specific deficiency for Smad2 in vivo leads to defects in TGF-beta-directed IgA switching and changes in B cell fate. J Immunol (2006) 0.93
A gene regulation system with four distinct expression levels. J Gene Med (2006) 0.93
P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone. Neuropharmacology (2013) 0.92
Identification of novel binding partners (annexins) for the cell death signal phosphatidylserine and definition of their recognition motif. J Biol Chem (2010) 0.91
Siglec-G regulates B1 cell survival and selection. J Immunol (2010) 0.91
Role of the Kaposi's sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation. J Virol (2010) 0.91
VH replacement rescues progenitor B cells with two nonproductive VDJ alleles. J Immunol (2006) 0.90
miR-148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2. Eur J Immunol (2015) 0.90
Adjusting transgene expression levels in lymphocytes with a set of inducible promoters. J Gene Med (2010) 0.90
Powered by pairing: the surrogate light chain amplifies immunoglobulin heavy chain signaling and pre-selects the antibody repertoire. Semin Immunol (2006) 0.89
Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production. Proc Natl Acad Sci U S A (2011) 0.89
Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration. Cell Res (2009) 0.89
Lytic Epstein-Barr virus infection in epithelial cells but not in B-lymphocytes is dependent on Blimp1. J Gen Virol (2012) 0.89
Constitutively unmasked CD22 on B cells of ST6Gal I knockout mice: novel sialoside probe for murine CD22. Glycobiology (2002) 0.89
B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo. Eur J Immunol (2012) 0.88
The pre-B cell receptor: turning autoreactivity into self-defense. Trends Immunol (2010) 0.88
CD22 regulates early B cell development in BOB.1/OBF.1-deficient mice. Eur J Immunol (2002) 0.87
Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks. FEBS Lett (2012) 0.87
microRNAs in rheumatoid arthritis: midget RNAs with a giant impact. Ann Rheum Dis (2011) 0.87
Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice. J Immunol (2014) 0.87
Phosphotyrosine recognition domains: the typical, the atypical and the versatile. Cell Commun Signal (2012) 0.86
High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells. Cell Commun Signal (2010) 0.86
CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling. Proc Natl Acad Sci U S A (2013) 0.86
Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance. PLoS Pathog (2013) 0.85
B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling. Eur J Immunol (2003) 0.85
Equal transcription rates of productively and nonproductively rearranged immunoglobulin mu heavy chain alleles in a pro-B cell line. RNA (2009) 0.85
B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice. J Immunol (2005) 0.85
Immunoglobulin mu heavy chains do not mediate tyrosine phosphorylation of Ig alpha from the ER-cis-Golgi. J Immunol (2003) 0.84
A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing. EMBO J (2011) 0.84
Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation. Gut (2013) 0.84