Published in FEBS Lett on April 25, 2012
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. Pharmacol Ther (2013) 2.64
Stress granules and cell signaling: more than just a passing phase? Trends Biochem Sci (2013) 2.01
The general phosphotransferase system proteins localize to sites of strong negative curvature in bacterial cells. MBio (2013) 0.81
How do disordered regions achieve comparable functions to structured domains? Protein Sci (2015) 0.81
Overcoming barriers and thresholds - signaling of oligomeric Aβ through the prion protein to Fyn. Mol Neurodegener (2013) 0.80
Very 'sticky' proteins - not too sticky after all? Cell Commun Signal (2012) 0.78
A Bayesian cluster analysis method for single-molecule localization microscopy data. Nat Protoc (2016) 0.77
What's in a loop? Cell Commun Signal (2012) 0.76
Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns. Blood (2012) 3.63
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2. Structure (2009) 1.89
Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76. EMBO J (2003) 1.38
Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes. J Cell Biol (2008) 1.35
Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix. J Biol Chem (2004) 1.21
GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol (2013) 1.19
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck. Biochemistry (2002) 1.17
Emerging roles of Abl family tyrosine kinases in microbial pathogenesis. Trends Biochem Sci (2008) 1.16
Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis. J Biol Chem (2010) 1.14
Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci U S A (2008) 1.13
A comprehensive structure-function comparison of hepatitis C virus strain JFH1 and J6 polymerases reveals a key residue stimulating replication in cell culture across genotypes. J Virol (2011) 1.07
Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells. Cell Commun Signal (2008) 1.05
Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation. Cancer Res (2009) 1.05
PI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitors. BMC Biol (2004) 1.04
Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells. Cell Commun Signal (2008) 1.03
The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal. Structure (2006) 1.01
Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts. J Immunol (2010) 1.00
Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers. Cell Commun Signal (2011) 0.99
Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer. Mol Cell Proteomics (2011) 0.95
Order and disorder in large multi-site docking proteins of the Gab family--implications for signalling complex formation and inhibitor design strategies. Mol Biosyst (2011) 0.95
ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63. Proc Natl Acad Sci U S A (2013) 0.94
An objective assessment of conformational variability in complexes of hepatitis C virus polymerase with non-nucleoside inhibitors. J Mol Biol (2011) 0.93
Role of the Kaposi's sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation. J Virol (2010) 0.91
Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration. Cell Res (2009) 0.89
Phosphotyrosine recognition domains: the typical, the atypical and the versatile. Cell Commun Signal (2012) 0.86
High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells. Cell Commun Signal (2010) 0.86
Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation. Gut (2013) 0.84
Self-organization and regulation of intrinsically disordered proteins with folded N-termini. PLoS Biol (2011) 0.82
Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy. Cell Commun Signal (2013) 0.81
Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. PLoS One (2013) 0.80
Prostaglandin-induced VASP phosphorylation controls alpha II-spectrin breakdown in apoptotic cells. Int Immunopharmacol (2007) 0.80
Application of ring-closing metathesis to Grb2 SH3 domain-binding peptides. Biopolymers (2011) 0.79
Signal transduction--receptors, mediators, and genes. Sci Signal (2009) 0.77
Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen. Bioorg Med Chem (2012) 0.76
Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies. BMC Cancer (2006) 0.75
Quantitative NMR analysis of Erk activity and inhibition by U0126 in a panel of patient-derived colorectal cancer cell lines. Biochim Biophys Acta (2013) 0.75
Signal transduction in the footsteps of goethe and schiller. Cell Commun Signal (2009) 0.75