Published in Anal Chem on April 01, 2010
Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research. Chem Rev (2013) 1.80
MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications. Histochem Cell Biol (2011) 1.12
MALDI Imaging Mass Spectrometry (MALDI-IMS)-application of spatial proteomics for ovarian cancer classification and diagnosis. Int J Mol Sci (2011) 1.12
Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact. Expert Rev Proteomics (2011) 0.99
MALDI imaging mass spectrometry--painting molecular pictures. Mol Oncol (2010) 0.96
Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry. PLoS One (2013) 0.88
Classification of astrocytomas and oligodendrogliomas from mass spectrometry data using sparse kernel machines. Conf Proc IEEE Eng Med Biol Soc (2011) 0.78
Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging. Conf Proc IEEE Eng Med Biol Soc (2012) 0.78
Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction. Sci Rep (2017) 0.75
The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol (2007) 49.11
Identification of human brain tumour initiating cells. Nature (2004) 38.87
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature (2006) 27.91
Identification of a cancer stem cell in human brain tumors. Cancer Res (2003) 24.02
Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS. Anal Chem (1997) 6.99
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res (2006) 6.77
Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nat Med (2001) 4.26
Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression. Clin Cancer Res (2004) 2.41
"Malignancy" in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer (1999) 2.40
Molecular imaging of proteins in tissues by mass spectrometry. Proc Natl Acad Sci U S A (2008) 2.38
Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res (2005) 2.06
Integrating histology and imaging mass spectrometry. Anal Chem (2004) 1.86
Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am J Pathol (2004) 1.76
Tissue profiling by mass spectrometry: a review of methodology and applications. Mol Cell Proteomics (2005) 1.64
Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. Clin Cancer Res (2005) 1.64
Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer Res (2004) 1.53
Assessing protein patterns in disease using imaging mass spectrometry. J Proteome Res (2004) 1.44
The accuracy of meningioma grading: a 10-year retrospective audit. Neuropathol Appl Neurobiol (2005) 1.22
The proteomic search for diagnostic biomarkers: lost in translation? Mol Cell Proteomics (2006) 1.18
Automated mass spectrometry imaging with a matrix-assisted laser desorption ionization time-of-flight instrument. J Am Soc Mass Spectrom (1999) 1.18
Matrix solution fixation: histology-compatible tissue preparation for MALDI mass spectrometry imaging. Anal Chem (2007) 1.05
Applications of SELDI-MS technology in oncology. J Cell Mol Med (2008) 0.98
Immunohistochemical analysis of p16INK4a, p14ARF, p18INK4c, p21CIP1, p27KIP1 and p73 expression in 271 meningiomas correlation with tumor grade and clinical outcome. Int J Cancer (2003) 0.92
Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature (2002) 15.36
Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med (2011) 12.76
Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res (2003) 8.06
Comparative analysis of algorithms for identifying amplifications and deletions in array CGH data. Bioinformatics (2005) 6.44
Localizing region-based active contours. IEEE Trans Image Process (2008) 4.39
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci (2010) 4.25
Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron (2012) 2.84
Image segmentation using active contours driven by the Bhattacharyya gradient flow. IEEE Trans Image Process (2007) 2.77
Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion. Proc Natl Acad Sci U S A (2011) 2.72
Epidemiology of intracranial meningioma. Neurosurgery (2005) 2.60
A 24-year-old woman with intractable seizures: review of surgery for epilepsy. JAMA (2008) 2.55
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas. J Clin Oncol (2004) 2.24
Benefit of ventriculoperitoneal cerebrospinal fluid shunting and intrathecal chemotherapy in neoplastic meningitis: a retrospective, case-controlled study. J Neurosurg (2011) 2.21
A soluble α-synuclein construct forms a dynamic tetramer. Proc Natl Acad Sci U S A (2011) 2.15
Automated identification of RNA conformational motifs: theory and application to the HM LSU 23S rRNA. Nucleic Acids Res (2003) 2.10
Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship. Proc Natl Acad Sci U S A (2010) 2.07
Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance. Cancer (2005) 1.97
A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs. Cancer Res (2011) 1.89
Neurosurgery certification in member societies of the WFNS: global overview. World Neurosurg (2011) 1.87
Flux driven automatic centerline extraction. Med Image Anal (2005) 1.84
Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency. Hum Mol Genet (2003) 1.79
Multiscale 3-D shape representation and segmentation using spherical wavelets. IEEE Trans Med Imaging (2007) 1.68
Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin. Hum Gene Ther (2003) 1.65
History of allergies and autoimmune diseases and risk of brain tumors in adults. Int J Cancer (2002) 1.62
Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival. PLoS Biol (2008) 1.61
Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth. Biochemistry (2008) 1.60
Targeting of melanoma brain metastases using engineered neural stem/progenitor cells. Neuro Oncol (2006) 1.57
A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma. Cancer Res (2006) 1.54
Knowledge-based 3D segmentation and reconstruction of coronary arteries using CT images. Conf Proc IEEE Eng Med Biol Soc (2004) 1.53
A framework for image segmentation using shape models and kernel space shape priors. IEEE Trans Pattern Anal Mach Intell (2008) 1.53
Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clin Cancer Res (2009) 1.52
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma. Neuro Oncol (2009) 1.51
Reproductive and hormonal factors and risk of brain tumors in adult females. Int J Cancer (2005) 1.50
Shape-Based Approach to Robust Image Segmentation using Kernel PCA. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit (2006) 1.50
Survival rates and patterns of care for patients diagnosed with supratentorial low-grade gliomas: data from the SEER program, 1973-2001. Cancer (2006) 1.49
A statistically based flow for image segmentation. Med Image Anal (2004) 1.48
Tracking deforming objects using particle filtering for geometric active contours. IEEE Trans Pattern Anal Mach Intell (2007) 1.45
Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression. Clin Cancer Res (2006) 1.44
Supratentorial low-grade glioma resectability: statistical predictive analysis based on anatomic MR features and tumor characteristics. Radiology (2006) 1.42
Non-rigid alignment of pre-operative MRI, fMRI, and DT-MRI with intra-operative MRI for enhanced visualization and navigation in image-guided neurosurgery. Neuroimage (2006) 1.41
In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas. Clin Cancer Res (2004) 1.40
Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy. Stem Cells (2009) 1.40
Neurosurgery certification in member societies of the WFNS: Europe. World Neurosurg (2011) 1.39
Immediate titanium mesh cranioplasty for treatment of postcraniotomy infections. World Neurosurg (2011) 1.39
Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes. Genome Res (2012) 1.39
Targeting rat brainstem glioma using human neural stem cells and human mesenchymal stem cells. Clin Cancer Res (2009) 1.38
The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth. J Biol Chem (2010) 1.38
Capturing intraoperative deformations: research experience at Brigham and Women's Hospital. Med Image Anal (2004) 1.35
A 3D interactive multi-object segmentation tool using local robust statistics driven active contours. Med Image Anal (2012) 1.33
Genetic polymorphisms in GSTM1, -P1, -T1, and CYP2E1 and the risk of adult brain tumors. Cancer Epidemiol Biomarkers Prev (2003) 1.28
Finsler tractography for white matter connectivity analysis of the cingulum bundle. Med Image Comput Comput Assist Interv (2007) 1.27
SNAI2/Slug promotes growth and invasion in human gliomas. BMC Cancer (2010) 1.26
Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers. Ann Neurol (2008) 1.26
Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis. J Neurochem (2004) 1.24
Lead, genetic susceptibility, and risk of adult brain tumors. Cancer Epidemiol Biomarkers Prev (2006) 1.23
NifS-mediated assembly of [4Fe-4S] clusters in the N- and C-terminal domains of the NifU scaffold protein. Biochemistry (2005) 1.21
Finsler active contours. IEEE Trans Pattern Anal Mach Intell (2008) 1.20
Exogenous hormone use and meningioma risk: what do we tell our patients? Cancer (2007) 1.20
Polymer Adsorption on Curved Surfaces: A Geometric Approach. J Phys Chem C Nanomater Interfaces (2007) 1.19
p53-dependent cell death signaling in neurons. Neurochem Res (2003) 1.19
Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma. Cancer Res (2007) 1.17
A generic framework for tracking using particle filter with dynamic shape prior. IEEE Trans Image Process (2007) 1.17
Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults. Cancer Epidemiol Biomarkers Prev (2007) 1.17
Development of stereotactic mass spectrometry for brain tumor surgery. Neurosurgery (2011) 1.16
Continuous intracranial administration of suberoylanilide hydroxamic acid (SAHA) inhibits tumor growth in an orthotopic glioma model. J Neurooncol (2007) 1.15
Image-guided neurosurgery at Brigham and Women's Hospital. IEEE Eng Med Biol Mag (2006) 1.14
Flattening maps for the visualization of multibranched vessels. IEEE Trans Med Imaging (2005) 1.14
Oxidative response gene polymorphisms and risk of adult brain tumors. Neuro Oncol (2008) 1.13
Blind deconvolution of medical ultrasound images: a parametric inverse filtering approach. IEEE Trans Image Process (2007) 1.13
Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging. Sci Rep (2013) 1.12
Despeckling of medical ultrasound images. IEEE Trans Ultrason Ferroelectr Freq Control (2006) 1.10
Statistical analysis of RNA backbone. IEEE/ACM Trans Comput Biol Bioinform (2006) 1.09
Sensitive and specific identification of wild type and variant proteins from 8 to 669 kDa using top-down mass spectrometry. Mol Cell Proteomics (2008) 1.09
PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model. Clin Cancer Res (2005) 1.08
A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop. J Biol Chem (2009) 1.08
Coronary vessel trees from 3D imagery: a topological approach. Med Image Anal (2006) 1.07
High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors. Int J Oncol (2010) 1.07
Single nucleotide RNA choreography. Nucleic Acids Res (2006) 1.06
Extent of intra-arterial calcification on head CT is predictive of the degree of intracranial atherosclerosis on digital subtraction angiography. Cerebrovasc Dis (2009) 1.06
Neural stem cell biology may be well suited for improving brain tumor therapies. Cancer J (2003) 1.05
Matrix solution fixation: histology-compatible tissue preparation for MALDI mass spectrometry imaging. Anal Chem (2007) 1.05
Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis. J Biol Chem (2007) 1.05
Genomic profiling reveals alternative genetic pathways of meningioma malignant progression dependent on the underlying NF2 status. Clin Cancer Res (2010) 1.04
Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche. Brain Res (2009) 1.03
Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers. Mol Cancer (2009) 1.03
Neurosurgery certification in member societies of the World Federation of Neurosurgical Societies: Asia. World Neurosurg (2011) 1.03
Techniques and complications of external lumbar drainage for normal pressure hydrocephalus. Neurosurgery (2008) 1.02
Specific genes expressed in association with progesterone receptors in meningioma. Cancer Res (2008) 1.02
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2010) 1.01
The Harvard Neurosurgical Service at the Children's Hospital Boston and Brigham & Women's Hospital, 1912-2007. Neurosurgery (2008) 1.00
Shape-driven 3D segmentation using spherical wavelets. Med Image Comput Comput Assist Interv (2006) 1.00
Solid-state NMR adiabatic TOBSY sequences provide enhanced sensitivity for multidimensional high-resolution magic-angle-spinning 1H MR spectroscopy. J Magn Reson (2008) 0.99
Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact. Expert Rev Proteomics (2011) 0.99